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Apakah yang anda perlu tahu tentang

KENCING MANIS
Definisi, punca, pengawalan, risiko, rawatan, pencegahan
Disediakan oleh: Muhamad Ikhwan B Muhamad Sayuti Muhamad Saddam B. Mohd Shariff Mohamad Taufik B Yusof Penasihat: Prof Madya Dr. Mohamed Azmi Ahmad Hassali

Apakah tanda dan gejala?


Kerap membuang air kecil dan selalu dahaga

Penurunan berat badan

Berasa sgt letih sepanjang masa

manis?

UBAT-UBATAN UNTUK KENCING MANIS

Terdapat dua jenis asas ubat kencing manis:

Ubat oral kencing manis. Insulin

Ubat oral kencing manis


Ubat oral kencing manis digunakan dalam rawatan penyakit kencing manis Jenis 2. Ubat dalam kategori ini tergolong dalam beberapa kelas, seperti:

1. Biguanides

(Mengurangkan penghasilan

glukosa dan meningkatkan tindakan insulin dalam otot dan lemak)

Glucophage XR

Dos: Tablet 500mg, 1 biji sekali


sehari diambil dengan makan malam. Kesansampingan: Gangguan perut, gangguan rasa, penurunan kadar penyerapanVitamin B12 semasa penggunaan jangka panjang

2. Sulfonylureas

Amaryl

3. Perencat Alfa-Glukosida

(Mengurangkan
Glucobay

penyerapan usus terhadap kanji seterusnya mengurangkan peningkatan glukosa)

Dos: 50-100 mg tiga kali


sehari. Perlu diambil bersama makanan.

Kesan sampingan:
Kembung perut, cirit-birit, sakit perut.

4. Perencat dipeptidyl peptidase

Januvia

(Meningkatkan penghasilan insulin dan menurunkan paras glukosa. gabungan terapi; 100 mg setiap hari. Boleh diambil dengan makanan atau tanpa makanan

Dos: Monoterapi atau

Kesan sampingan: Sakit


perut, loya, muntah, ciritbirit.

5. Gabungan ubat-ubatan

Dos: Dos individual.


Janumet

Permulaan 50 mg/500 mg dua kali sehari. Perlu diambil bersama makanan.

Kesan sampingan:
Kembung perut, muntah, sakit kepala, sakit perut, hilang selera makan.

Insulin
Peranannya adalah untuk membantu selsel dalam badan menggunakan glukosa untuk tenaga.

1.Tindakan pantas Insulin lispro (Humalog) Insulin aspart (NovoLog)

2.Tindakan pendek Humulin R Novolin R 3.Ttindakan pertengahan Humulin N Novolin N

4. Tindakan berpanjangan Insulin glargine (Lantus) 5. Pracampuran Insulin lispro protamine/insulin lispro (HumalogMix50/50, Humalog Mix75/25) Insulin aspart protamine/insulin aspart (NovoLogMix 50/50, NovoLog Mix 70/30) NPH insulin/regular insulin (Humulin 70/30, Novolin70/30).

Dimana anda boleh mendapatkan bantuan tentang kencing manis? Bagaimana untuk mencari program tentang

Untuk mencari program atau maklumat


tentang diabetis, hubungi
The National Diabetes Institute (NADI) National Diabetes Institute (NADI)No. 1, Jalan SS 3/50,University Garden,47300 Petaling Jaya,Selangor, MalaysiaTelefon: 0378761676/78761677Fax: 03-7876167 E-mel: enquiry@nadidiabetes.com.myWebsite: www.diabetesmalaysia.com.my

kencing manis?

Bagaimana untuk mendapatkan maklumat Untuk mendapat maklumat dan penjagaan


kencing manis, hubungi:
Persatuan Diabetes Malaysia PDM Secretariat:No. 2, Lorong 11/4E,46200 Petaling JayaSelangor Darul Ehsan Telefon: 03-79574062 Fax: 0379604514Emel: info@diabetes.org.my Laman: www.diabetes.org.my

mengenai kencing manis?

Waktu operasi: Isnin-Jumaat: 9.00pg - 4.30ptg (rehat -1.00ptg to 2.00ptg)Sabtu: 9.00pg - 12.30ptg Tutup hari ahad dan cuti umum

Rujukan
1. Diabetes Information Hub. Can Diabetes Be Cured. [homepage on the Internet]. 2012 [cited 2012 Apr 24]. Available from: http://diabetesinformationhub.com/CanDiabetesBeCured.php 2. Malaysian Diabetes Association. What is Diabetes. [homepage on the Internet]. 2012 [cited 2012 Apr 24]. Available from: http://www.diabetes.org.my/article.php?aid=5 3. National Diabetes Institute. All About Diabetes. [homepage on the Internet]. 2012 [cited 2012 Apr 23]. Available from: http://www.diabetesmalaysia.com.my/section.php?sid=1

4. Ucsf Medical Center. Diabetes Mellitus Signs and Symptoms. [homepage on the Internet]. 2012 [cited 2012 Apr 23]. Available from: University of California San Francisco, Web site: http://www.ucsfhealth.org/conditions/diabetes_mellitus/signs_and_symptoms.html
5. Web Md. Risk Factors for Diabetes. [homepage on the Internet]. 2012 [cited 2012 Apr 24]. Available from: http://diabetes.webmd.com/risk-factors-for-diabetes

6. Ministry of Health Malaysia. Diabetes Mellitus. [homepage on the Internet]. 2010 [cited 2012 Apr 21]. Available from: http://www.myhealth.gov.my/myhealth/index.php/en/dewasa/01penyakit0102diseas e02/01kencing-manis0102diabetes-mellitus02

7. International Diabetes Federation. Complications of Diabetes. [homepage on the Internet]. 2011 [cited 2012 Apr 21]. Available from: http://www.idf.org/complicationsdiabetes 8. U.S. National Library of Medicine. Type 2 Diabetes: Risk factors. [homepage on the Internet]. 2012 [cited 2012 Apr 23]. Available from: National Institutes of Health, U.S. Department of Health and Human Services Web site: http://www.nlm.nih.gov/medlineplus/ency/article/002072.htm 9. MIMS Malaysia. Antidiabetic Agents. [database on the Internet]. 2011 [cited 2012 May 6]. Available from: National Institutes of Health, U.S. Department of Health and Human Services Web site: http://www.mims.com/ 10. MIMS. 127th ed. Malaysia: UBM Medica Asia Pte Ltd; 2011. 11. Hermans MP, Ahn SA, Rousseau MF. The multi-faceted outcomes of conjunct diabetes and cardiovascular familial history in type 2 diabetes. J Diabetes and its Complications 2012. 12. Kramer H, Cao G, Dugas L, Luke A, Copper R, Arvizu Rd. Increasing BMI and waist circumference and prevalence of obesity among adults with Type 2 diabetes: the National Health and Nutrition Examination Surveys. J Diabetes and its Complications 2010; 24(6):368-374. 13. Noto H, Osame K, Sasazuki T, Noda M. Substantially increased risk of cancer in patients with diabetes mellitus: A systematic review and meta-analysis of epidemiologic evidence in Japan. J Diabetes and its Complications 2010; 24(5):345 353. 14. Bruce DG, Davis WA, Cull CA. Diabetes education and knowledge in patients with type 2 diabetes from the community: The Fremantle Diabetes Study. J Diabetes and its Complications 2003; 17(2):82-89.