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I - , , .

, ,
-, , 2011.


5-
57.1%
93.5% ( ) 29.5% ()
-
25-60% 15-25%
Ries LAG, Young JL et al., (editors). SEER Survival Monograph: Cancer Survival
Among Adults: U.S. SEER Program, 1988-2001, Patient and Tumor Characteristics.
National Cancer Institute, SEER Program, NIH Pub. No. 07-6215, Bethesda, MD,
2007.




+/
III-IVA-B .
- / +

(salvage surgery).


( )

22%
-12%
+ 6%
5%


II .
III-IV- .
10% ( < 0.01)
.
13,145 ( : 55% - II .,
84% - III-IV .)
. Gandey et al. Adjuvant radiotherapy for H&N cancers. Surveillance,
Epidemiology, and End Results [SEER] American Society of Clinical
Oncology 43rd Annual Meeting: Abstract 6087. Presented June 4, 2007.

ICRU
International Commission on Radiation Units
and measurements

GTV CTV

GTV V ( )
V Vkm ( )
PTV Vp ( )
Treated Volume Vt ( )
Irradiated Volume Vo ( )

.., .. . . .
-, 2008


:
GTV - 60-66 1, 66-70 2 .
V 50-54 (boost)
60-66
:
V 50-54 (boost)
60-66
L.W. Brady, H.-P. Heilmann et al. Radiation Oncology. An Evidence-Based Approach.
2008, Springer Verlag, Berlin, Heidelberg.
Eric K. Hansen, Mack Roach III. Handbook of Evidence-Based Radiation Oncology 2nd
Edition Springer Science + Business Media, 2010
NCCN Clinical Practice Guidelines in Oncology. Head & Neck Cancers. Version 2.2011.

/ ( )

/ ( )



(DRR) .
3 .

32

11 ( 3 30)


5
PTV 90%
98.8 0.6%,
95.6 1.4% (p = 0.02)
86.2%
(
45 ) 78.8%
,
-


1.

, ,

,
.
2. 5

3D CRT
(IMRT).

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