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  • Tubex Test

    Diunggah oleh

    Resky Maynora
    93 tayangan7 halaman
    The document describes a new serologic test called TUBEX that detects anti-Salmonella O9 antibodies to diagnose typhoid fever. TUBEX uses magnetic particles coated with S. Typhi LPS and latex particles carrying anti-O9 monoclonal antibodies; if a patient's sample contains the antibodies, it will inhibit binding of the particles, leaving the supernatant purplish blue and indicating a positive result. The test was found to have high sensitivity and specificity for detecting typhoid fever, with 80.36% of patients with 7-14 day fevers testing positive.

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    The document describes a new serologic test called TUBEX that detects anti-Salmonella O9 antibodies to diagnose typhoid fever. TUBEX uses magnetic particles coated with S. Typhi LPS and latex particles carrying anti-O9 monoclonal antibodies; if a patient's sample contains the antibodies, it will inhibit binding of the particles, leaving the supernatant purplish blue and indicating a positive result. The test was found to have high sensitivity and specificity for detecting typhoid fever, with 80.36% of patients with 7-14 day fevers testing positive.

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    Attribution Non-Commercial (BY-NC)
    Unduh sebagai PPT, PDF, TXT atau baca online dari Scribd
    Tandai sebagai konten tidak pantas
    93 tayangan7 halaman

    Tubex Test

    Diunggah oleh

    Resky Maynora
    The document describes a new serologic test called TUBEX that detects anti-Salmonella O9 antibodies to diagnose typhoid fever. TUBEX uses magnetic particles coated with S. Typhi LPS and latex particles carrying anti-O9 monoclonal antibodies; if a patient's sample contains the antibodies, it will inhibit binding of the particles, leaving the supernatant purplish blue and indicating a positive result. The test was found to have high sensitivity and specificity for detecting typhoid fever, with 80.36% of patients with 7-14 day fevers testing positive.

    Hak Cipta:

    Attribution Non-Commercial (BY-NC)
    Unduh sebagai PPT, PDF, TXT atau baca online dari Scribd
    Tandai sebagai konten tidak pantas
    dari 7

    1

    New serologic diagnosed test for typhoid fever


    TUBEX detects anti-Salmonella O9 (immunoglobulin

    M [IgM]) antibodies High sensitivity and high specifity 80,36 % positive in 7-14 days fever

    Coloured indicator latex particle carrying anti-O9

    monoclonal antibodies Magnetic particle coated with S. Typhi LPS (lipopolysacharide) Those two particle binds and sedimented leave the redish behind (red latex particle)

    If anti-O9 antibodies (+) in the reaction mixture

    inhibit the binding of the blue particles to the magnetic particles Consequently, the supernatant remains purplish blue (unchanged from the beginning) due to the presence of blue particles and also, in a lower concentration, of red particles.

    10 8 6

    KUANTITATIF HASIL POSITIF BILA > +4

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