ICROS-SICE International Joint Conference 2009 August 18-21, 2009, Fukuoka International Congress Center, Japan

Start

( x1 + x2 ) + x5 ( x3 x4 )

Initialization

+ +
x1

Fitness calculation

*
x2

Selection

Crossover

x3

x5

Mutation

x4

Max. Generation?

Finish

- 3679 -

PR0002/09/0000-3679 400 2009 SICE

Protein expression levels Normalization

Physiological Activities Normalization

Synthesis

Synthesis

Discarding data in both tails

Discarding data in both tails

Corresponding

300M

10M P.A. : Physiological Activity

- 3680 -

 2
+ 10

+ 2

- 3681 -

1.5

ESTIMATED VALUE

0.5 2

0 0 0.5 1 MESURED VALUE 1.5 2 1.5

ESTIMATED VALUE

G1

ERK2

G2

0.5

Survivin

G3
0
TXNRD1

0.5

G4

1 MESURED VALUE

1.5

G6
ERK2 TXNRD1 p53

G5

TXNRD1

1.5

ESTIMATED VALUE

0.5

0 0 0.5 1 MESURED VALUE 1.5 2

- 3682 -

1.6

1.4

1.2

ESTIMATED VALUE

0.8

0.6

0.4

0.2

0 0 0.2 0.4 0.6 0.8 MESURED VALUE 1 1.2 1.4 1.6

G1

G7

G2

ERK2

HSP90

G6
MxA HSP70 p53

G3

G4

Survivin

G5

Survivin

ERK2

- 3683 -

- 3684 -