Mechanism of Action
Indication
Contraindication
Side-Effects
Nursing Responsibilities
Generic Name:
Ceftriaxone Sodium
Lowers respiratory infections caused by Streptococcus pneumonia, Staphylococcus aureus, Haemophilus influenza, E. coli, Enterobacter aerogenes. Intra-abdominal infections caused by E.coli, Klebsiella pneumoniae
Contraindicated with allergy to cephalosporins or penicillins. Use cautiously with renal failure, lactation, pregnancy
GI: Nausea, vomiting, diarrhea, anorexia, Increase bleeding pseudomembranous effects with oral colitis anticoagulants HEMATOLOGIC: bone marrow depression dec. WBC, platelets, Hct LOCAL: pain, inflammation of IV Site OTHER: superinfections, disulfiram-like reaction with alcohol Disulfiram-like reactions may occur if alcohol is taken
BEFORE: Do Skin Testing into the intradermal area Protect Drug from light Do not mix ceftriaxone with other antimicrobial drug DURING: Use a separate syringe when giving this drug Have Vitamin K available in case of hypoprothrombinemia occurs AFTER: Discontinue if hypersensitivity occurs Monitor Blood levels in patients taking this drug