Sample is a portion of the population A sample must representative for the population. Sampling Error 5% = 0.05 (1). Random (2). Equal probability
The idea of sampling is to study a part of the population in order to gain information about the whole population.
Advantages of a sample : 1. Reduce finance, personnel, material, lower cost 2. Results more quickly, shorter time 3. Better accuracy 4. More comprehensive data
Sample size depends on : 1. Study design 2. Estimated magnitude of the parameter being studied ( = p ) 3. Variability of the parameter being studied (s) 4. Level or Error ( = ) 5. Level of precision ( L ) 6. Data analysis plan 7. Practical consideration
1. Longitudinal study design requires larger sample than cross-sectional study Cluster sampling design requires larger sample than simple random sampling 2. p = prevalence being studied, q = 1 p when p = 0.5 then maximun sample size is reached
3. The rarer the variable being studied, the larger the sample size
4. The more heterogeneous the variable in the population, the larger the sample size. 5.The higher the level of precision desired, the larger the sample size.
6. Multivariate data analysis required larger sample size than univariate analysis. 7. Practical consideration : money, man power, time allocation.
Besar sampel tergantung desain penelitian 1. Desain prevalensi (survei), cross sectional a). Data kategori b). Data numerik 2. Desain membandingkan dua mean a). t-independent b). t-berpasangan 3. Desain korelasi 4. Desain kohort atau eksperimen 5. Desain kasus-kontrol
n2 = n1 + 10%
n2 = sampel akhir.
Tabel Distribusi Normal Z ------------------------Semakin kecil 0.05 1.960 maka semakin besar 0.025 2.248* nilai Z nya. 0.020 2.326 0.01 2.576 semakin besar 0.005 2.813* ukuran sampelnya. 0.001 3.291 ------------------------- Rujuk Table A3
(Z) 2 p q n = ---------------L2
n2 = n1 + 10%
n2 = sampel akhir.
n2 = 58 + (10%)(58) = 64
= 0.50
n = 96
N = 666
Key : n = 89
N = 666
Rumus Sample Size utk Survei / prevalensi Data Numerik. Contoh : Kadar HB bumil. ( gram/dL ). Z (s) n = { ----------- } 2 d = Tingkat kemaknaan / kesalahan type I. s = Simpang baku = Standard deviation. d = Presisi.
Contoh :
Studi survei tentang kadar Hb bumil di Cemp Putih Barat, waktu .. th ..
Dari jurnal dikertahui simpang baku = 0.45 g/dL Presisi = 10 % dan = 5 % Berapa besar sampel yg diperlukan ?
Z (s) n = { ----------- } 2 d
Uji t-independent
(Z + Z) 2 s 2 n = 2 ---------------------------(mean1 mean2) 2
n = besar sampel minimal. = kesalahan tipe I. = kesalahan tipe II. s = standard deviation gabungan.
Tabel Beta
( 1 ) = Power penelitian.
s = 1.5 mean1 mean2 = 1 g/dL alpha = 5% Power = 80% Sample size = ? (Z + Z) 2 s 2 n = 2 ---------------------------(mean1 mean2) 2 (1.96 + 0.842) 2 (1.5) 2 n = 2 ---------------------------------- = 35 (1 ) 2 for each group
T-test pairs
(Z + Z) 2 s 2 n = -----------------------(mean dif) 2
s =1.2 g/dL mean dif = 0.5 g/dL Power = 80% (1.96 + 0.842) 2 (1.2)2 n = -------------------------------- = 45 ( 0.5) 2 = 5%
5. Rumus Sample Size Studi Case-control. 1. 2. 3. 4. Proporsi kontrol = p2, misal = 0.10 Perkiraan besar OR, misal = 3.0 Besar Besar presisi = e p2 (OR) maka p1 = ---------------------(1-p2) + p2(OR) p1 = Proporsi kasus.
Perbedaan antara Log dg Ln. 1. Log 2 = 0.3010 2. Log 3 = 0.4771 3. Log 4 = 0.6021 Ln 2 = 0.6931 Ln 3 = 1.0986 Ln 4 = 1.3863
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