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Imiquimod cream - An immune response modifier approved for the treatment of external genital and perianal warts in adults,

imiquimod cream has been reported to be effective in the treatment of molluscum contagiosum[26, 27] ; imiquimod cream may be used in conjunction with cantharidin[28] Cantharidin - Several studies report that cantharidin, a chemovesicant that can be used in combination with imiquimod, is effective in treating molluscum contagiosum; to test the patient's response to therapy, treat only a few lesions on the initial visit[28] Tretinoin - This agent has reportedly been successful in the treatment of small molluscum contagiosum lesions Bichloracetic acid Trichloroacetic acid Salicylic acid Lactic acid Glycolic acid Silver nitrate

Tretinoin, cantharidin, and imiquimod may be dispensed to the patient with application instructions and close follow-up, although some recommend application in the office. Bichloracetic acid, trichloroacetic acid, salicylic acid, lactic acid, glycolic acid, and silver nitrate must be applied in the office by the physician. Topical podophyllotoxin 0.5% cream self-administered twice daily for 3 weeks has been reported effective in a placebo-controlled, double-blind study.[29] Reports have suggested that subcutaneous interferon alfa administered intralesionally may be useful in immunocompromised children. A case report noted the efficacy of topical cidofovir in the treatment of disseminated molluscum in immunodepressed patients.[6] Cidofovir diphosphate was reported to inhibit molluscum contagiosum virus DNA polymerase activity.[30] Previous Next Section: Benign Neglect