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Periodontitis or periodontal disease are inflammation of the tissues supporting the teeth and is an irreversible lesion, which in time leads to loss of teeth in dental arches. .Periodontitis is evolutionary stage and / or complication gingivitis Apical periodontitis - inflammatory lesion or apical parodoniului dystrophy caused by local or .general factors Apical periodontitis, is a consequence of endodontic infection and manifests as a host defense reaction of microbes in the root canal system. This is viewed as an active struggle between infected radicular pulp and defenders host the damaged surface of infected radicular pulp and periodontal ligament, which leads to local inflammation, resorption of hard tissues, destruction of other periapical tissues, and eventual formation of various histopathological categories of apical periodontitis, called usually periapical lesions