ANEMIA BERDASAR PATOFISIOLOGI

DECREASED PRODUCTION INCREASED DESTRUCTION

DECREASED PRODUCTION
HEMOGLOBIN SYNTHESIS
IRON DEFICIENCY THALASSEMIA ANEMIA ON CHRONIC DISEASE

DNA SYNTHESIS
MEGALOBLASTIC ANEMIA

STEM CELL
APLASTIC ANEMIA MYELOPROLIFERATIVE LEUKEMIA

BONE MARROW INFILTRATION

CARCINOMA LYMPHOMA

INCREASED DESTRUCTION
BLOOD LOSS
CA COLON CA CERVIX GASTRITIS EROSIVA

HEMOLYSIS INTRINSIC
MEMBRAN : SPHEROCYTOSIS, ELLIPTOCYTOSIS HEMOGLOBIN : SICKLE CELL, UNSTABLE HEMOGLOBIN GLYCOLYSIS : PYRUVATE KINASE DEFICIENCY OXIDATION : G6PD DEFICIENCY

HEMOLYSIS EXTRINSIC
IMMUN : WARM ANTIBODY, COLD ANTIBODY MICROANGIOPATTHIC : TTP, HUS, MECHANICAL CARDIAC VALVE, INFECTION : ENDOCARDITIS, CLOSTRIDIAL HIPERSPLENISME

ANEMIA BERDASAR MCV

MICROCYTIC
DEFISIENSI BESI THALASSEMIA ANEMIA OF CHRONIC DISEASE RING SIDEROBLASTIC

MACROCYTIC MEGALOBLASTIC
VIT B12 DEFICIENCY FOLATE DEFICIENCY

MACROCYTIC NONMEGALOBLASTIC
MYELODISPLASIA CHEMOTERAPI LIVER DISEASE MIXODEMA

NORMOSITIC
ANEMIA APALSTIC LEUKEMIA DLL