SPERMATOGENESIS

Spermatogenesis is the production of sperm from the basic germ cells Occur in the seminiferous tubules in the testes It begins at puberty

1. 2. 3. 4. 5. 6. 7. 8.

Basal lamina (membrane) (not recognizable) Myofibroblast Fibrocyte Sertoli's cell Spermatogonia Various stages of the germ cells during spermatogenesis Spermatozoon Lumen

The spermatogenesis can be subdivided into two successive sections

The first comprises the cells from the spermatogonium up to and including the secondary spermatocyte and is termed spermatocytogenesis The second one comprises the differentiation/ maturation of the sperm cell, starting with the spermatid phase and is termed spermiogenesis (or spermiohistogenesis).

Spermatocytogenesis and Spermiogenesis

(1) Spermatogonia are the basic germ cells. They are diploid (2n). (2) One of these spermatogonia undergoes MITOSIS, and it is called a primary spermatocyte. It is diploid (2n). (3) The primary spermatocyte undergoes MEIOSIS I to produce two secondary spermatocytes. These are now haploid (n (4) Each of these secondary spermatocytes undergoes MEIOSIS II to each produce two spermatids. Spermatids are haploid (n). The result is 4 total spermatids. (5) Spermatids mature into the sperm we know, and these sperm cells are called spermatozoa. They are then ready to leave the body and fertilize ovum

Spermatids sperm cells : spermiogenesis. Nuclear condensation. Acrosome formation Flagellum formation. Cytoplasma reduction

The approximate 64 day cycle of the spermatogenesis can be subdivided into four phases that last differing lengths of time:

Mitosis of the spermatogonia

16 days

Up to the primary spermatocytes

First meiosis

24 days

For the division of the primary spermatocytes to formsecondary spermatocytes

Second meiosis

A few hours

For engendering the spermatids

Spermiogenesis

24 days

Up to the completed sperm cells

Total

~64 days

TERIMA KASIH