Brand name: Metformin

Generic name: Metformin HCl

Indication: Management of type 2 DM
Drug classification: Antidiabetic, Biguanides
Mechanism of action: decreases hepatic glucose production, decreasing intestinal
absorption of glucose and improves insulin sensitivity (increases peripheral
glucose uptake and utilization)
Dosage: 500mg bid
Special precaution: concurrent renal disease, geriatric patients, chronic alcohol abuse,
serious medical conditions, patients undergoing stress, hypoxia,
hyperthyroidism, pregnancy, lactation, children <10 yrs old
Pregnancy risk category: C
Adverse reaction: GI: abdominal bloating, diarrhea, nausea, vomiting, unpleasant
metallic taste Endo: hypoglycemia others: lactic acidosis, decreased cobalamin
level
Contraindicated in: hypersensitivity, metabolic acidosis, dehydration, sepsis,
hypoxemia, hepatic impairment, excessive alcohol use, renal dysfunction
Form: Tablet 400 mg
Nursing responsibilities:
 Assess clients diseases such as renal disease and liver diseases
 Monitor client’s glucose level
 Ask client whether his an alcoholic or not