Malaria - History

Alphonse Laveran

Sir Patrick Manson

Sir Ronald Ross

Giovanni Grassi

Malaria Geographic distribution

Malaria United States

Malaria transmission 1957-1994

Malaria Life cycle

Malaria - Vectors

Anopheles freeborni

Malaria Vectors (cont.)

Anopheles balabacensis

A. gambiae

A. freeborni

A. stephensi

Malaria Vectors (cont.)

Malaria - Sporogony

Malaria - Sporogony

Plasmodium falciparum Sporozoites and liver schizonts

Malaria - Merozoite

Malaria Red blood cell invasion

Malaria Red blood cell invasion

P. falciparum Blood stages

Uninfected RBC

4 hr.

2 hr.

12 hr.

Malaria Blood stages (cont.)

Malaria Blood stages (cont.)

Malaria - Cytoadherence

Malaria and Sickle cell anemia

Malaria

Malaria - Immunity

Malaria Immunity (cont.)

Malaria - Vaccination

Malaria - Diagnosis

Malaria Diagnosis (cont.)

Po

Pf Pv Pm

Immunofluorescent antibody Malaria PCR

Malaria - Treatment

Artemisinin

Malaria - Prevention