Waktu

(menit)
0
10
20
30
40
50
60

x1
0
0.796
0.786
0.783
0.774
0.772
0.770

x2
0
0.863
0.788
0.778
0.781
0.778
0.773

x3
C1 (mg/mL)C2 (mg/mL)C3 (mg/mL)
0
0
0
0
0.784
3.455
3.801
3.393
0.790
3.403
3.413
3.424
0.785
3.387
3.362
3.398
0.775
3.341
3.377
3.346
0.775
3.331
3.362
3.346
0.769
3.320
3.336
3.315

rerata
0
3.549
3.413
3.382
3.355
3.346
3.324

Q (mg)
0
709.848
682.645
676.446
670.937
669.215
664.738

Kurva Profil Pelepasan Obat

Waktu VS %Terlepas
200
y = 1.6628x + 73.883
R = 0.4315

150

kurva profil pelepasan

obat

100

Linear (kurva profil

pelepasan obat)

50
0
0

20

40

60

80

Fk
Qtot (mg) %terlepas[AUC]tn-1--tn [AUC]0-tn Luas segi4
0
0
0
0
0
0
0.000 709.848 141.970 3549.242
3549.242
5000.000
17.746 700.391 140.078 7051.197 10600.439
10000.000
34.812 711.259 142.252 7058.247 17658.686
15000.000
51.723 722.660 144.532 7169.594 24828.280
20000.000
68.497 737.712 147.542 7301.860 32130.139
25000.000
85.227 749.966 149.993 7438.387 39568.526
30000.000
4331.835

n Obat

kurva profil pelepasan

obat
Linear (kurva profil
pelepasan obat)

DE

0
70.985
106.004
117.725
124.141
128.521
131.895