Struktur Kulit dan Jaringan Subkutan

Organ terbesar menutupi are 1.5-2 m2 15% BB

2 lapisan - stratified squamous epithelium - epidermis

- deeper connective tissue layer dermis

hypodermis 1 - 2 mm (kelopak mata -- bahu) Tebal-tipis epidermis (stratum korneum) Hanya kelenjar keringat

Epidermis
Epitel pipih berlapis

berkeratin Ujung saraf 4 zona (5)

Avascular

Stratum Basale
Selapis epitel sel kuboid/

low columnar epithel 3 tipe 1. keratinosit 2. Melanosit 3. Sel Merkel

Stratum Spinosum

Keratinosit Sel dendritik desmosom

Stratum Granulosum
2- 3 lapis keratinosit pipih(> tebal
kerato-hyalin granule membrane-coating vesicles

Stratum Lucidum
Lapisan transluscent (tebal) Eleidin Tidak ada nukleus/organel

Stratum Corneum
30 lapis sel keratinosit mati

Stratum corneum

Stratum lucidum
Stratum granulosum Stratum spinosum

Stratum basale

Dermis
0.2-4 mm
Serabut kolagen, elastin, retikuler Pembuluh darah, kelenjar keringat, kelenjar sebasea,

folikel rambut dan akar kuku Ujung saraf sensorik jaringan otot Papilla dermal area sensitive

 2 lapisan Lapisarn papiler jaringan ikat areolar -- imun Lapisan retikuler jaringan ikat padat

Reseptor sensorik kulit

Meissner's corpuscle Free nerve ending

Pacinian corpuscle

Hair follicle receptor (root hair plexus)

Spinal cord

Histology

External Internal

hipodermis
Jaringan subkutan, fasia superfisial
Reservoar energi, insulator

Skin Color
Hemoglobin
Melanin Karoten

Fungsi
Barier
Sintesis vit D Fungsi sensorik

Termoregulasi

Rambut
Organ asesoris
Keratin keras ikatan disulfida Pillus pili

Filamen tipis sel keratin

Folikel Hampir di seluruh tubuh

Struktur Rambut dan Folikel

3 jenis : lanugo, velus, rambut tipe terminal 3 zona 1. Bulb 2. Akar 3. shaft Papil 3 lapisan 1. Medulla 2. Korteks 3. kutikula

Hair Bulb Hair Shaft (visible hair) Hair Root (embedded)

Folikel
Tabung diagonal tertanam dlm

dermis hipodermis 2 lapisan epithelial root sheath connective tissue root sheath. Serat saraf dan otot Stem cell

Hair Root

Hair Follicle

Hair Bulb

Hair Papilla

Hair follicle

(smooth muscle)

Sebaceous (oil) gland

Kuku
Sel keratin
1 mm/mig

Kelenjar keringat
Merokrin(ekrin)
Apokrin Kelenjar tubulus sederhana Duktus: sel epitel kuboid berlapis(dermis)

keratinosit(epidermis)
Sel mioepitel -- parasimpatis

Sweat Glands

Sudoriferous (sweat) glands Cross section

Low magnification

High magnification

Kelenjar sebasea