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GENOGRAM

HPN HPN DM

HPN

HPN HPN HPN HPN

LEGEND:
Male
Female
Deceased
HPN The Patient
HPN - Hypertension
DM DM - Diabetes Mellitus type 2
PATHOPHYSIOLOGY OF HYPERTENSION
NON MODIFIABLE:
• Age
• Genetics
MODIFIABLE
High Sodium Diet
Lifestyle
Stress

Stress
Genetic Alteration
Excess Na Intake
SNS overactivity RAAS activation & excess Cell membrane
alteration
Renal Na Retention
Functional constriction of
Increased vessels Functional
Contractility
Increased fluid volume constriction &
and venous constriction structural
Increased Peripheral Decreased blood
Increased CO hypertrophy
Resistance flow to organs
Increased Preload and
Contractility Increased
Compensation: Increased CO Dizziness Peripheral
Headache Resistance
Increased CO Blurring of Vision

Increased CO

Hypertension

Increased pressure stretches the walls of the heart

Cardiomegaly

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