CVS DRUGS: Anti-arrythmic: Amiodarone Flecainide

Calcium channel blocker: Amlodipine:

Calcium channel blocker - modify ca ion mvmt across cell membs in bvs and cardiac mm; redu vasc sm mm contrac - vasodiln: redu TPR Hypertension; Angina; Caution: Liver/heart probs; angina @ rest; preg/brf SFX: HA; flushes; abdo pain; nausea; ankle oedema, fatigue, dizziness
Diltiazem Felodipine Nifedipine Veramapil

Anti-platelet drug: Asasantin Retard Aspirin:

Anti-platelet (inhibits thromboxane prod thus platelet aggrg; NSAID (inhibits COX1>2 irreversibly thus prostagln prod); antipyretic Pain (HA/tooth/period); Fever; Inflammatory dis;
Clopidogrel Dopyridamole

Beta blocker:

Atenolol:

Beta-adrenergic receptor blocker. Cardioselective for B1 receptors. Reduces heart rate/FOC. Hypertension; arrhythmias; angina SFX: Nausea; GIT probs; dizzy; fatigue; Rarer: cold ex; insom; hypotensn; impotence; red libido; CI: sinus node dysf; cardiogenic schock; pulm oed; Caut: abrupt withdrawal inc symp; mask hypothy
Propranolol Sotalol

Statin: Atorvastatin:

Statin. Inhibits HMG-CoA reductase enzyme inv'd in cholesterol synth in liver. Hypercholesterolaemia; hyperlipidaemia; CVSD prevention. Only used after diet/exx/weight reduction failed. SFX: MM ache/W; HA; Const/Diarr/Naus; Dizzy; tired; nosebleed; memory probs; depressn; sex probs. CI:Liver disease; Preg/BrF; Risk rhabdo.
Fluvastatin Pravastatin Simvastatin Rosuvastatin

Diuretic: Bendroflumethiazide (thiazide):

Thiazide diuretic; Red. NaCl resorpn in DCT, inc. water loss w. NaCl. Hypertension; Oedema fr heart failure

SFX: Gout (>3yrs); Nausea; Vomiting; GIT probs; Postural hypotension; Hypotension; Hyponatraemia/kalaemia; Hypercalcaemia
Bumetanide (loop) Furosemide (loop):

Loop diuretic: inhibits NaCl resorp in ascending Loop of Henle Hypertension; Oedema of congestive heart failure SFX: Nausea; GIT probs; Dry mouth; Postural hypotension; Blurred vision/HA/tiredness/photophobia; Hypokalaemia; Hyperglycaemia; Gout
Indapamine (thiazide)

Nitrate: Glyceril trinitrate (GTN) Isosobide mononitrate

Angiotensin- II receptor antagonist: Candesartan Irbesartan Losartan

Cardiac glycoside: Digoxin:

Cardiac glycoside - increases myocardial FoC & BP; decreases AV node conductivity; reduces HR Atrial fibrillation; atrial flutter Not first choice for congestive heart failure. SFX common (narrow therap. index): Dizzy; Blurred/yellow vision; Nausea/vomiting/diarr (inc GIT motility); Skin rash; Drowsy; insomn;

Angiotensin-converting enzyme (ACE) inhibitor: Enalapril Lisonopril Ramipril

Potassium channel activator: Nicorandil Oral anticoagulant: Warfarin

BLOOD: Drug used in megaloblastic anaemia-folate deficiency Folic acid Drug used in megaloblastic anaemia-pernicious anaemia Hydroxocobalamin (injection)