Brand Name: Anestacon, Dermaflex

Generic Name: Lidocaine

Indications: Cardiac arrythmias, Ventricular ectopy, ventricular tachycardia,
Ventricular fibrillation
Drug Classification: Local Anesthetic
Mechanism of Action: Class IB antiarrhythmic; suppresses automaticity of
conduction tissue, by increasing electrical stimulation threshold of ventricle,
HIS-Purkinje system, and spontaneous depolarization of the ventricles during
diastole by a direct action on the tissues; blocks both the initiation and
conduction of nerve impulses by decreasing the neuronal membrane’s
permeability to sodium ions, which results in inhibition of depolarization with
resultant blockade of conduction
Dosage: Adult: not more than 200-300 mg lidocaine administered during a 1-hr period.
Children 30 mcg/kg/min by infusion, following appropriate bolus administration
(1 mg/kg).
Special Precaution: Renal, cardiac or hepatic failure; sinus bradycardia; diabetes
mellitus; digitalis toxicity w/ AV block.
Pregnancy Risk Category: B (per manufacturer);C (based on expert analysis)
Adverse Reactions: CV: Hypotension. CNS: Positional headache. Miscellaneous:
Shivering
Contraindications:
 Known hypersensitivity to amide-type local anesthetics
 Patients with Adams-Stoke syndrome or with severe degree of S-A, A-V
 Intraventricular heart block (without a pacemaker)
Form: INJ – 1g/250 mL
Nursing Responsibilities:
 Monitor fluid balance
 Assess IV site
 Monitor blood pressure, heart rate & pulse