Materials & Streams Report

April 11, 2014

for lab 3
1. OVERALL PROCESS DATA
Annual Operating Time
Recipe Batch Time
Recipe Cycle Time
Number of Batches per Year
MP = Undefined

7,907.49h
54.71h
33.56h
235.00

- Page 1 -

2.1 STARTING MATERIAL REQUIREMENTS (per Section)

Section

Starting Material Active Product

Amount
Needed
(kg
Sin/kg
MP)

Main Section

(none)

Unknown Unknown Unknown Unknown

(none)

Molar
Yield
(%)

Mass
Yield
(%)

Gross
Mass
Yield
(%)

Sin = Section Starting Material, Aout = Section Active Product

2.2 BULK MATERIALS (Entire Process)

Material

kg/yr

kg/batch

Biomass
Media
Water
Air
Acetone
Glycine
Urea
Methanol
TOTAL

11,750
105,750
2,350,000
2,278,266
1,501,229
561,475
469,504
2
7,277,977

50.000
450.000
10,000.000
9,694.750
6,388.209
2,389.256
1,997.891
0.010
30,970.115

kg/yr

kg/batch

11,750
105,750
2,350,000
2,278,266
1,501,229
561,475
469,504
2
7,277,977

50.000
450.000
10,000.000
9,694.750
6,388.209
2,389.256
1,997.891
0.010
30,970.115

kg/kg MP

2.3 BULK MATERIALS (per Section)

SECTIONS IN: Main Branch
Main Section
Material
Biomass
Media
Water
Air
Acetone
Glycine
Urea
Methanol
TOTAL

kg/kg MP

- Page 2 -

2.4 BULK MATERIALS (per Material)

Biomass
Procedure
Main Section (Main Branch)
P-1
TOTAL

Media
Procedure
Main Section (Main Branch)
P-1
TOTAL

Water
Procedure
Main Section (Main Branch)
P-1
TOTAL

Air
Procedure
Main Section (Main Branch)
P-1
TOTAL

Acetone
Procedure
Main Section (Main Branch)
P-3
TOTAL

Glycine
Procedure
Main Section (Main Branch)
P-3
TOTAL

Urea
Procedure
Main Section (Main Branch)
P-3
TOTAL

% Total

kg/yr

kg/batch

100.00
100.00

11,750
11,750

50.000
50.000

% Total

kg/yr

kg/batch

100.00
100.00

105,750
105,750

450.000
450.000

% Total

kg/yr

kg/batch

100.00
100.00

2,350,000
2,350,000

10,000.000
10,000.000

% Total

kg/yr

kg/batch

100.00
100.00

2,278,266
2,278,266

9,694.750
9,694.750

% Total

kg/yr

kg/batch

100.00
100.00

1,501,229
1,501,229

6,388.209
6,388.209

% Total

kg/yr

kg/batch

100.00
100.00

561,475
561,475

2,389.256
2,389.256

% Total

kg/yr

kg/batch

100.00
100.00

469,504
469,504

1,997.891
1,997.891

kg/kg MP

kg/kg MP

kg/kg MP

kg/kg MP

kg/kg MP

kg/kg MP

kg/kg MP

- Page 3 -

Methanol
Procedure
Main Section (Main Branch)
P-4
TOTAL

% Total

kg/yr

kg/batch

100.00
100.00

2
2

0.010
0.010

kg/kg MP

2.5 BULK MATERIALS: SECTION TOTALS (kg/batch)

Raw Material
Biomass
Media
Water
Air
Acetone
Glycine
Urea
Methanol
TOTAL

Main Section
50.000
450.000
10,000.000
9,694.750
6,388.209
2,389.256
1,997.891
0.010
30,970.115

2.6 BULK MATERIALS: SECTION TOTALS (kg/yr)

Raw Material
Biomass
Media
Water
Air
Acetone
Glycine
Urea
Methanol
TOTAL

Main Section
11,750
105,750
2,350,000
2,278,266
1,501,229
561,475
469,504
2
7,277,977

- Page 4 -

3. STREAM DETAILS
Stream Name
Source
Destination
Stream Properties

Feed
INPUT
P-1

water
INPUT
P-1

Air
INPUT
P-1

Vent
P-1
OUTPUT

Activity (U/ml)
Temperature (C)
Pressure (bar)
Density (g/L)
Total Enthalpy (kW-h)
Specific Enthalpy (kcal/kg)
Heat Capacity (kcal/kg-C)

0.00
25.00
1.01
999.97
0.00
0.00
1.00

0.00
25.00
1.01
994.70
0.00
0.00
1.00

0.00
25.00
1.01
1.18
0.00
0.00
0.24

0.00
37.00
1.01
1.14
43.14
3.82
0.24

50.000
0.000
450.000
0.000
0.000
0.000
500.000
500.015

0.000
0.000
0.000
0.000
0.000
10,000.000
10,000.000
10,053.239

0.000
0.000
0.000
7,437.016
2,257.734
0.000
9,694.750
8,221,312.821

0.000
314.902
0.000
7,446.672
1,945.764
0.000
9,707.338
8,494,958.001

Broth
P-1
P-2

Liquid
P-2
P-3

Solids
P-2
OUTPUT

Acetone
INPUT
P-3

0.00
5.00
0.87
1,002.76
- 243.64
- 19.96
1.00

0.00
11.31
1.01
999.69
- 147.98
- 13.67
1.00

0.00
11.31
1.01
1,006.87
- 18.81
- 13.67
1.00

0.00
25.00
1.01
786.58
0.00
0.00
0.52

0.000
176.000
45.000
9.000
10,270.000
10,500.000
10,471.071

0.000
0.000
40.608
8.122
9,267.551
9,316.280
9,319.125

0.000
176.000
4.392
0.878
1,002.449
1,183.720
1,175.647

6,388.209
0.000
0.000
0.000
0.000
6,388.209
8,121.515

Component Flowrates (kg/batch)

Biomass
Carb. Dioxide
Media
Nitrogen
Oxygen
Water
TOTAL (kg/batch)
TOTAL (L/batch)

Stream Name
Source
Destination
Stream Properties
Activity (U/ml)
Temperature (C)
Pressure (bar)
Density (g/L)
Total Enthalpy (kW-h)
Specific Enthalpy (kcal/kg)
Heat Capacity (kcal/kg-C)

Component Flowrates (kg/batch)

Acetone
Biomass
Impurity
MAB
Water
TOTAL (kg/batch)
TOTAL (L/batch)

- Page 5 -

Stream Name
Source
Destination
Stream Properties

Glycine
INPUT
P-3

Urea
INPUT
P-3

Waste Liquid
P-3
OUTPUT

MAB
P-3
P-4

Activity (U/ml)
Temperature (C)
Pressure (bar)
Density (g/L)
Total Enthalpy (kW-h)
Specific Enthalpy (kcal/kg)
Heat Capacity (kcal/kg-C)

0.00
25.00
1.01
1,470.94
0.00
0.00
0.43

0.00
25.00
1.01
1,230.00
0.00
0.00
0.48

0.00
11.31
1.01
999.69
- 147.85
- 13.67
1.00

0.00
25.00
1.01
994.70
0.00
0.00
1.00

2,389.256
0.000
0.000
0.000
0.000
2,389.256
1,624.303

0.000
0.000
0.000
1,997.891
0.000
1,997.891
1,624.303

0.000
40.608
0.000
0.000
9,267.551
9,308.158
9,311.001

0.000
0.000
8.040
0.000
0.000
8.040
8.083

Other solids
P-3
OUTPUT

Methanol
INPUT
P-4

0.00
25.00
1.01
947.69
0.00
0.00
0.49

0.00
25.00
1.01
789.61
0.00
0.00
0.61

0.00
5.00
8.87
1,001.70
- 0.19
- 19.95
1.00

0.00
12.00
8.87
802.08
- 0.00
- 7.91
0.61

6,388.209
2,389.256
0.081
0.000
0.000
1,997.891
10,775.437
11,370.203

0.000
0.000
0.000
0.000
0.010
0.000
0.010
0.013

0.000
0.000
0.804
7.236
0.010
0.000
8.050
8.037

0.000
0.000
0.000
0.000
0.010
0.000
0.010
0.012

Component Flowrates (kg/batch)

Glycine
Impurity
MAB
Urea
Water
TOTAL (kg/batch)
TOTAL (L/batch)

Stream Name
Source
Destination
Stream Properties
Activity (U/ml)
Temperature (C)
Pressure (bar)
Density (g/L)
Total Enthalpy (kW-h)
Specific Enthalpy (kcal/kg)
Heat Capacity (kcal/kg-C)

MAB Crystal Waste Methanol

P-4
P-5
P-5
OUTPUT

Component Flowrates (kg/batch)

Acetone
Glycine
MAB
MAB Crystal
Methanol
Urea
TOTAL (kg/batch)
TOTAL (L/batch)

- Page 6 -

Stream Name
Source
Destination
Stream Properties
Activity (U/ml)
Temperature (C)
Pressure (bar)
Density (g/L)
Total Enthalpy (kW-h)
Specific Enthalpy (kcal/kg)
Heat Capacity (kcal/kg-C)

MAB Product
P-5
OUTPUT
0.00
12.00
8.87
999.44
- 0.12
- 12.98
1.00

Component Flowrates (kg/batch)

MAB
MAB Crystal
TOTAL (kg/batch)
TOTAL (L/batch)

0.804
7.236
8.040
8.045

- Page 7 -

4. OVERALL COMPONENT BALANCE (kg/batch)

COMPONENT
Acetone
Biomass
Carb. Dioxide
Glycine
Impurity
MAB
MAB Crystal
Media
Methanol
Nitrogen
Oxygen
Urea
Water
TOTAL

INITIAL

INPUT

OUTPUT

FINAL

IN-OUT

0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
0.000
11.994
3.641
0.000
0.000
15.635

6,388.209
50.000
0.000
2,389.256
0.000
0.000
0.000
450.000
0.010
7,437.016
2,257.734
1,997.891
10,000.000
30,970.115

6,388.209
176.000
314.902
2,389.256
45.000
1.764
7.236
0.000
0.010
7,446.672
1,945.764
1,997.891
10,270.000
30,982.703

0.000
0.000
0.098
0.000
0.000
0.000
0.000
0.000
0.000
2.337
0.611
0.000
0.000
3.047

0.000
- 126.000
- 315.000
0.000
- 45.000
- 1.764
- 7.236
450.000
0.000
0.000
315.000
0.000
- 270.000
0.000

- Page 8 -

5. EQUIPMENT CONTENTS
FR-101
Procedure

Operation

P-1
P-1
P-1
P-1
P-1
P-1
P-1

START
CHARGE-1 (Charge)
CHARGE-2 (Charge)
HEAT-1 (Batch Heating)
FERMENT-1 (Batch Kinetic Fermentation)
COOL-1 (Batch Cooling)
TRANSFER-OUT-1 (Transfer Out)

C-101
Procedure

Operation

P-3

P-3
P-3
P-3

START
AFTER AUTO-INIT
EQUILIBRATE-1 (Column Equilibration
(Simplified))
LOAD-1 (EBA Column Loading)
ELUTE-1 (Column Elution (Simplified))
WASH-1 (Column Wash (Simplified))

R-101
Procedure

Operation

P-4
P-4
P-4
P-4
P-4

START
TRANSFER-IN-1 (Transfer In)
CHARGE-1 (Charge)
REACT-1 (Batch Stoich. Reaction)
TRANSFER-OUT-1 (Transfer Out)

FDR-101
Procedure

Operation

P-3

P-5
P-5
P-5

START
AFTER AUTO-INIT
DRY-1 (Freeze Drying)
TRANSFER-OUT-1 (Transfer Out)

Time (in h)

Volume (in L)

0.000
1.167
2.926
3.409
27.409
28.559
33.559

0.000
500.015
10,553.253
10,599.654
10,592.424
10,471.071
0.000

Time (in h)

Volume (in L)

28.559
28.559

0.000
9,319.125

29.059

9,319.125

29.633
29.733
29.833

0.000
0.000
0.000

Time (in h)

Volume (in L)

29.833
29.933
30.183
42.183
42.446

0.000
8.083
8.096
8.037
0.000

Time (in h)

Volume (in L)

42.446
42.446
54.446
54.709

0.000
8.037
8.045
0.000

- Page 9 -