Drug Data Classification Mechanism of Action Indication Contraindications Adverse Reaction Nursing Responsibilities

Generic Name Pharmacologic Enters target cells and binds -Replacement therapy Concentrations CNS: Vertigo, headache, Before
Hydrocortisone Class to cytoplasmic receptor; in adrenal cortical - Allergy to any paresthesias, insomnia, - Assess for contraindications.
component of the drug seizures, psychosis - Assess body weight, skin color,
Adrenal cortical initiates many complex insufficiency
- Fungal infections CV: Hypotension, shock, HPN V/S, urinalysis, serum electrolytes,
Trade Name steroid reactions that are responsible - Allergic states – and heart failure secondary to X-rays, CBC.
Cortef, Solu- Corticosteroid for its anti-inflammatory, severe or - Amebiasis fluid retention, - Arrange for increased dosage when
Cortef, Glucocorticoid immunosuppressive incapacitating allergic - Hepatitis B thromboembolism, patient is subject to unusual stress.
Hydrocortone, (glucocorticoid), and salt- conditions - Vaccinia or varicella thrombophlebitis, fat embolism, - Do not give live vaccines with
Cortenema Therapeutic retaining (mineralocorticoid) - Hematologic - Antibiotic-resistant cardiac arrhythmias immunosuppressive doses of
infections Dermatologic: Thin, fragile hydrocortisone.
Class actions. Some actions may disorders skin, petechiae, ecchymoses, - Observe the 15 rights of drug
- Immunosuppression
Content Hormone be undesirable, depending - Ulcerative colitis purpura, striae, subcutaneous administration.
Hydrocortisone on drug use. Precaution fat atrophy
Pregnancy - Kidney disease EENT: Cataracts, glaucoma, During
Dosage category increased IOP - Give daily before 9am to mimic
- Liver disease Endocrine: Amenorrhea, normal peak diurnal corticosteroid
20-240 mg/day in C - Cirrhosis irregular mens, growth levels.
single dose or - Hypothyroidism retardation, decreased - Space multiple doses evenly
divided doses - Ulcerative colitis with carbohydrate tolerance and throughout the day.
impending perforation DM, cushingoid state, HPA - Use minimal doses for minimal
Availability - Diverticulitis suppression systemic , duration to minimize adverse effects.
Tablets: 5, 10, 20 - Recent GI surgery hyperglycemia - Do not give IM injections if patient
- Active or latent peptic GI: Peptic or esophageal ulcer, has thrombocytopenic purpura.
mg;
pancreatitis, abdominal - Taper doses when discontinuing
Oral suspension: ulcer
distention, nausea, vomiting, high-dose or long-term therapy.
10 mg/5 mL; - Inflammatory bowel increased appetite and weight
Injection: 25, 50 disease gain After
mg/mL, 100, 200, - Hypertension Hematologic: Na and fluid - Monitor client for at least 30
500, 1,000 mg/vial - Heart failure retention, hypocalcemia, minutes.
- Thromboembolic increased blood sugar, - Educate client on the side effects of
tendencies increased serum cholesterol, the medication and what to expect.
- Osteoporosis decreased T3 and T4 levels - Instruct client to report pain at
- Convulsive disorders Hypersensitivity: injection site.
Anaphylactoid or - Instruct client to take drug exactly
- Metastatic carcinoma
hypersensitivity reactions as prescribed.
- Diabetes mellitus Musculoskeletal: Muscle - Dispose of used materials properly.
- TB weakness, steroid myopathy - Document that drug has been
- Lactation and loss of muscle mass, given.
osteoporosis, spontaneous
fractures
Other: Immunosuppression,
aggravation or masking of
infections, impaired wound
healing
Source: Source: Source: Source: Source: Source: Source:
Karch, Amy: 2009 Karch, Amy: 2009 Karch, Amy: 2009 Lippincott’s Nursing Karch, Amy: 2009 Lippincott’s Karch, Amy: 2009 Lippincott’s Karch, Amy: 2009 Lippincott’s Nursing Karch, Amy: 2009 Lippincott’s Nursing
Lippincott’s Nursing Drug Lippincott’s Nursing Drug Guide, p. 592 Nursing Drug Guide, p. 592 Nursing Drug Guide, p. 592 Drug Guide, p. 593-594 Drug Guide, p. 594-595
Guide, p. 592 Drug Guide, p. 592