Holding Tube Feeds for Residuals: How Much is Too Much? Feb 1997 a study from Cedars-Sinai Medical Center shows that at commonly encountered rates of formula delivery and gastric emptying, the gastric residual volume would plateau at a volume well within that found in the post prandial stomach. Nov 2008 Am J Crit Care publishes study stating no consistent relationship between aspiration and GRVs. Aug 2012 South Med J survey study concluded the decision to withhold NGT feeding varied significantly among the nursing staff A.S.P.E.N.- 500mL or greater Cleveland Clinic- 400mL or greater ADA Guidelines (c. 2008)- 250mL or greater American Gastroenterology Association (c. 1995)- 200mL or greater It all depends on your care team consensus In a review article, Measurement of Gastric Residual Volume: State of the Science, published in 2000 in MEDSURG Nursing, Edwards and Metheny reported that the literature contained a variety of recommendations for what is considered a high GRV, ranging from 100 to 500 mL. Some sources have even (incorrectly) suggested holding tube feedings for a GRV of greater than 30 mL, or 1.5 times the flow rate, or even one half of the hourly flow rate. -Todays Dietitian June 2010 Reignier J, Mercier E, Le Gouge A, et al. Effect of not monitoring residual gastric volume on risk of ventilator-associated pneumonia in adults receiving mechanical ventilation and early enteral feeding: a randomized controlled trial. JAMA. 2013;309(3):249-56 In terms of protection against Ventilator Assocated Pneumonia (VAP), a protocol of enteral nutrition management without Gastric Residual Volume (GRV) monitoring is not inferior to a similar protocol including GRV monitoring.