1.

Tinjauan kimia
a. Monografi zat aktif
Nama IUPAC : 1 - [fenil-(4-phenylphenyl) metil]-1H-imidazol
CAS Number: 60628-96-8
Rumus : C
22
H
18
N
2

b. Identifikasi
Ultra violet spectrophotometry
Bifonazole (200 mg) was taken in a 100 ml volumetric flask and volume was made up
with methanol. One ml of the solution was pipetted out and diluted to 100 ml with
methanol. Examined between 200-400nm.The solution showed maximum absorption at
254,4nm
2. Tinjauan farmakologi
a. Farmakokinetik
b. farmakodinamik
3. Alasan pemilihan
4. Tinjauan formulasi
a. Preformulasi
b. Formula standar
c. Sediaan yang beredar
Mycospor : 1 gram krim mengandung 10 mg bifonazol, 1 ml cairan mengandung 10 mg
bifonazol (mengadung alkohol). PT Bayer Indonesia
d. Formula yang direncanakan
e. Alasan pengambilan bahan
f. Formula akhir
g. Cara kerja
5. Etiket brosur
6. Etiket kemasan obat
7. Etiket kotak