Perbandingan Efek Air Rebusan Daun Salam (Syzygium

polyanthum (Wight) Walp) dan Daun Seledri(Apium graviolens

L. ) terhadap Peningkatan Kadar HDL Darah
Tikus Wistar Model Dislipidemia
(The Comparison of Bay (Syzygium polyanthum (Wight) Walp)
Leaf and Celery (Apium graviolens L.) Leaf Infusion Effect on
Increasing HDL Level in Dyslipidemic Wistar Rats Model)
Abstract
Dyslipidemia is a condition in which there is abnormal blood lipid profiles, including
decreasing HDL level. Flavonoids are substances containing antidislipidemia effects
that can be found in the bay and celery leaves. The aim of this study was to explore
bay leaf and celery leaf infusion effect on increasing HDL level in dyslipidemic rat
model. The type of this study was true experimental research using pre-post test
control group design with 24 wistar rat (Rattus novergicus) as the sample. The rats
were induced by high fat diet and PTU for two weeks then each group were treasted
either simvastatin (K+), bay leaf infusion (P1), celery leaf infusion (P2), or aquadest
(K-) for a week. HDL was measured pre induction, pre treatment, and post treatment
used endpoint method with Mikrolab 300. Delta of HDL levels in group K+ was 0.68
mg/dl, in group P1 was -1.72 mg/dl, in group P2 was 1.97 mg/dl, and in group K+
was 2.05 mg/dl. Paired T-test data analysis showed p=0.745 in group K+, p=0.420 in
group P1, p=0.309 in group P2, p=0.057 in group K+, and one way ANOVA data
analysis showed p=0.745. The study concluded that there was no difference between
bay leaf infusion and celery leaf infusion on increasing HDL levels in wistar rats.
Keywords: dyslipidemia, HDL, bay leaf infusion, celery leaf infusion, wistar rats