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  • Transcription Factors and Gene Regulation

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    Transcription factors are proteins that bind to DNA at promoter regions and regulate the initiation of transcription. They work by either activating or repressing gene expression. Transcription factors form transcription initiation complexes that recruit RNA polymerase to start transcription. Some factors are present constitutively in cells while others are activated at specific developmental stages or in response to hormones and growth factors.

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    Transcription Factors

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    Transcription factors are proteins that bind to DNA at promoter regions and regulate the initiation of transcription. They work by either activating or repressing gene expression. Transcription factors form transcription initiation complexes that recruit RNA polymerase to start transcription. Some factors are present constitutively in cells while others are activated at specific developmental stages or in response to hormones and growth factors.

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    47 tayangan6 halaman

    Transcription Factors and Gene Regulation

    Diunggah oleh

    burhan
    Transcription factors are proteins that bind to DNA at promoter regions and regulate the initiation of transcription. They work by either activating or repressing gene expression. Transcription factors form transcription initiation complexes that recruit RNA polymerase to start transcription. Some factors are present constitutively in cells while others are activated at specific developmental stages or in response to hormones and growth factors.

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    © All Rights Reserved
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    dari 6

    Transcription Factors

    A2 Biology Topic 7

    Transcription is initiated by RNA polymerase and


    protein transcription factors binding to DNA
    RNA polymerase

    Promotor region
    DNA

    Gene

    Transcription factors

    Gene is switched on by formation of the transcription


    initiation complex binding to the promotor region

    RNA synthesis

    DNA

    Transcription initiation complex

    Gene

    Transcription factors

    Some are present in all cells


    Some are present in particular cells

    Most created in an inactive


    form and activated by
    hormones or growth factors

    Some are present at a particular


    stage of development

    Activator molecules stimulate


    the binding of the transcription
    initiation complex

    Genes are switched off by repressor molecules


    Repressor molecule binds
    to promotor region

    Repressor molecule

    promotor

    gene

    Repressor molecule binds


    to transcription factors

    Repressor molecule
    (Inactive transcription
    factor)
    promotor

    gene

    Repressor molecule

    Repressor molecules prevent the formation of the


    transcription initiation complex

    Activity 7.21

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