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Energenetics, Inanovate Combine Next

Generation Proteins and Blood Assay
Technologies to Combat Worst Diseases
Energenetics, a biotech-food company based in Iowa, and Inanovate, Inc., a medical
technology company based in North Carolina, are collaborating to advance protein-based
diagnostics and therapeutics for faster recovery and survival from diseases, such as cancer,
HIV/AIDS, and Alzheimer's.
Fort Madison, IA, May 15, 2015 /PressReleasePing/ - Energenetics, a biotech-food
company based in Iowa, and Inanovate, Inc., a medical technology company based in North
Carolina, are collaborating to advance protein-based diagnostics and therapeutics for faster
recovery and survival from diseases, such as cancer, HIV/AIDS, and Alzheimer's.

The two companies plan to identify then produce plant--based "designer" botanical proteins in
new food product lines that will provide higher nutritional protein therapies that could result in
faster recovery and survival from many diseases. Diseases that will initially be targeted will
be HIV/AIDS and cancer patients suffering from cachexia and sarcopenia (muscle wasting
that usually causes a dramatic loss of weight and appetite).

These botanical proteins are mixtures of intact protein amino acid chains (Perfect Plant
Proteins) isolated from specialty, non-GMO grains, ancient grains, and seeds, and other
botanical sources without denaturation (damage that occurs to protein amino acids due to
cooking and steeping in harsh acids for days which causes an unraveling of the protein amino
acid chains, leading to spoilage, off-tastes, and odors).

When these special botanical proteins are mixed in specific proportions, a higher level of
nutrition can be achieved that is superior to animal proteins but without the negative side
effects of animal proteins (high cholesterol and saturated fats). Because Perfect Plant
Proteins are totally natural and organic, they can be incorporated into many food product lines
for example, cereals, pastas, cookies, mixes, spreads, and breads -- to replace animalbased proteins. These Perfect Plant Protein foods can also be used to combat diseases
associated with malnutrition throughout the world.

Inanovate/Energenetics Synergies
Inanovate was introduced to Energenetics disease fighting activities (HIV patient treatment)
by Inanovate advisor and investor Glen Wegner who lives in Boston. Wegner, a doctor and a
lawyer, immediately recognized the potential synergy between the two companies respective
technologies.

Inanovate is capable of detecting diseases such as cancer in their earliest stages by

screening multiple protein biomarkers simultaneously from a single blood sample, says
Wegner. The Inanovate platform (called the Bio-ID) will be used to help identify and select
the Perfect Plant Proteins that will achieve the highest therapeutic value, as well as develop
companion diagnostic tests that can help optimally target the developed therapies.

There is a vital need to develop faster and more accurate medical diagnostics that can
provide earlier detection and improved tracking of cancer and other diseases says David Ure,
President and CEO of Inanovate. Each cancer and disease exhibits a unique set of protein
biomarkers in the bloodstream that may appear at different times and in different
concentrations. A more rapid and accurate method to assay these biomarkers will not only
lead to earlier detection of these diseases, but can aid in the development and targeting of
novel nutritional protein therapies based on mixtures of plant-based botanical proteins and
their amino acids that are non-animal based that can lead to the earlier treatment and
recovery from such diseases. The Inanovate Technology Platform can also monitor the
patient immune system during afflictions from diseases and this is where the Perfect Plant
Proteins can be targeted to provide not only the highest nutritional levels, but used to
strengthen the immune system.

Inanovate has received approximately six million dollars in start-up funding to date from both
private investors as well has high profile medical research entities and the US Government
and is now raising an additional two million dollars that will lead to the commercial launch
of their Bio-ID platform.

Blood Assay Technologies

The team of medical scientists at Inanovate (www.inanovate.com ), Inc has developed a
faster and more accurate blood assay platform that can simultaneously screen for multiple
biomarkers from a single minute blood sample. The worldwide biomarker market is presently
estimated at $20 billion annually, growing to a forecasted $40 billion by 2018 [Biomarkers
Market Global Trends & Forecasts (2013 2018)]. 40% of this market ($8 billion annually) is
related to the discovery, validation and clinical use of biomarkers for complex diseases like
cancer and heart disease. The benefits of the Inanovate platform are specifically designed to
address the needs of these complex diseases, wherein the accurate measurement of multiple
different biomarkers in one low cost test is key.

This platform can lead to the rapid detection of the unique biomarkers exhibited by each
disease, for example, breast, ovarian, prostate, lung, and pancreatic cancers, and other
diseases such as cachexia, sarcopenia (muscle wasting) HIV/AIDS, diabetes, MS,
Alzheimer's, autism. The earlier detection of these diseases and/or their recurrences can lead
to increased chances of treatment and survival of such diseases. Presently under
development on the Inanovate platform is a monitoring test that can detect breast cancer
recurrence in its earliest stage when treatment may still be curative. And more recently, the
Inanovate platform can also be used to monitor the immune system through protein
biomarkers in both the bloodstream and saliva. The unique capability of the Inanovate
platform to accurately detect and measure multiple biomarkers across a near unlimited
concentration range in one single low cost test enables a new generation of more sensitive
and specific diagnostic tests for complex multi-variant diseases such as cancer (any assay,
one multiplex, one run, one dilution). The savings in cost, time and sample use delivered
through the platform mean the Inanovate technology can be utilized worldwide in detection
and combating disease.

The Inanovate Bio-ID is a new generation of blood screening technology that provides
users with accurate, highly sensitive kinetic data on multiple biomarkers in real-time
for the rapid detection of disease.

Equally important is the development of new therapeutic proteins developed by Energenetics (

www.egembrs.com ) which can be used in the treatment of diseases (proteohomeostasis).
The new protein isolation process developed by Energenetics, in conjunction with the USDA,
recovers intact protein amino acid chains from many botanical and grain sources without
denaturation. Energenetics believes that mixtures of these natural protein isolate amino acids
can be used to target nutritional protein therapies for specific diseases as well as used to
strengthen the immune system during afflictions from disease.

These new botanical Perfect Plant Proteins and amino acids can also be incorporated into
many palate pleasing consumer food products, such as cereals, pastas, cookies, shakes,
imitation cheeses, and spreads that will provide protein replenishment and nourishment at the
cellular level that will allow for faster muscle recovery and help sustain the human body during
recovery from many diseases. Scientists also believe these highly nutritious "medical foods"
can be used to replace the vile and horrible tasting animal and synthetic-based feeding tube
applications now used to achieve patient nutritional therapy through the use of such Perfect
Plant Protein Products which are nutraceuticals (proteonutraceuticals or proteohomeostasis-the use of proteins in the treatment of treat disease).

Energenetics (www.egembers.com) has worked in conjunction with the USDA to develop

these new protein isolate extraction technologies. Its new Corn Protein Isolates that are

produced from the USDA's Heart Friendly Corn contains ninety-five percent pure protein and
have been successfully tested in many consumer products such as breads and cookies. The
Natick US Army R&D Command Center over all meals worldwide for all military services, has
expressed interest in this produce in their Meals Ready to Eat (MREs), which could provide
our servicemen with faster muscle recovery, especially in critical combat zones.

Energenetics has had queries from major food processors interested in fortifying such
products as breads, cookies, cheeses, ice creams, yogurts, potato chips, cereals and even
beer with its Corn Protein Isolates that could benefit from protein fortification and the
substitution of protein for fat and other high-caloric ingredients. In essence, these products
will be fortified by Energenetics' "medical or therapeutic proteins" allowing these same
proteins to become available for the diet of everyday consumers. The company has also
developed resistant starches and plant-based omega 3/6/9 essential oils, that, when
combined with their protein isolates, will result in guilt-free consumption of pastas, breads,
snacks and cheeses by weight-conscious consumers. The company has recently made an
indirect proposal through the United Nation's World Food Programme, the world's largest
humanitarian agency fighting hunger worldwide which reaches more than 97 million people
suffering from the devastating "kwashiorkor disease" (malnutrition from starvation) where over
3 million children die from such debilitating diseases each year.

Furthermore, Energenetics protein isolates represent an ideal alternative to conventional

meat proteins because it is healthier to consume and has the potential to sharply accelerate a
shift to vegetable protein substitutes for beef, pork and poultry. This shift could free up
considerable arable land resources currently used for expensive animal husbandry, it would
result in a far more efficient and environmentally sustainable way of producing food protein
from crops such as corn, rice, soy, canola, barley, tomatoes, and potatoes. One study
showed that if quality plant-based proteins could be produced that would be comparable to
animal protein (reducing our reliance on the hog, the cow, or the chicken) this would result in
a 1000% increase in the availability of food protein to feed our starving planet, and, it would
better help protect our planet's natural resources.

A Not for Profit Foundation to Sponsor Clinical Trials

The two companies plan to establish a non-profit foundation
(see: http://www.proteintherapeuticsfoundation.org)
and enter into an alliance agreement to collaborate in conducting a series of clinical trials at a
number of major medical institutions to test their combined platforms for the early detection of
many diseases where feedback from the Inanovate Platform will validate the efficacies of
Energenetics protein therapies that will be critical in the development of nutritional and
therapeutic protein treatments of such diseases.

One trial that will be sponsored by Energenetics is a clinical trial to determine the efficacy of
that will test Energenetic's Perfect Protein Products and the Inanovate Platform for combating
cachexia and sarcopenia (muscle wasting) in cancer and HIV/AIDS patients. These patients
sometimes suffer from dramatic loss of weight and appetite due to these afflictions.
Energenetics hopes to garner interest from several high-profile non-profit funding groups
interested in alleviating malnutrition and its resulting diseases on a worldwide basis.

We are excited to collaborate with Energenetics through to help develop, optimize and target
new protein enhanced food products that have the potential of treating a broad range of
diseases from cancer to HIV, says Ure. Our platform, the Bio-ID, is a great match for
Energenetics' needs as it uniquely enables users to accurately screen across an almost
unlimited range of proteins in a single, low-cost test, using a patented process called
Longitudinal Assay Screening (LAS). Ure points out that this process can be thought of as
extreme time-lapse photography for protein detection.

Unlike other protein detection tools and platforms, which take a single photo or image of
target proteins within a sample, our technology takes many such images (photos) throughout
the course of a test, says Ure.

This gives us a much richer and informative insight into the presence and concentration of
each target protein with the sample. Leveraging this unique advantage by working with
Energenetics will help to identify and validate new protein isolates for potential therapeutic use
within food products, Ure emphasizes, adding, Building on this foundation, we will use our
platform to screen the candidate protein isolates to validate their therapeutic efficacy and track
identified protein biomarkers that can be used to help better target these new therapies.

Contact:
Inanovate, Inc.
David Ure, CEO

Energenetics Energies LLC

Sammy Mayfield Pierce, CEO

dure@inanovate.com

smp.ege@gmail.com

www.inanovate.com
2 Davis Drive, STE 13169,

www.egembrs.com
PO Box 845, Keokuk, IA 52632

RTP, NC 27709

Ph. 319-535-0760

Ph:617-610-1712

###
PO Box 845, Keokuk, Iowa 52632
Sammy Mayfield Pierce
Energenetics
319-535-0760
smp.ege@gmail.com
www.proteintherapeuticsfoundation.org
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