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PROPOSAL PROGRAM KREATIVITAS MAHASISWA

JUDUL PROGRAM
SECOPIN:
Scoparone dari Ekstrak Artemisia annua l.
sebagai Inhibitor Hepatotoksik Niasin dalam Minuman Berenergi

BIDANG KEGIATAN:
PKM PENELITIAN

Diusulkan oleh:
Pudyo Kriswhardani
Cicik Tri Juliani
Asis Fitriana
I Nyoman K Agratama
Sri Respati Ayunignsih

132010101028
132010101039
132010101005
142010101065
142210101082

Angkatan 2013
Angkatan 2013
Angkatan 2013
Angkatan 2014
Angkatan 2014

UNIVERSITAS JEMBER
JEMBER
2015

ii

DAFTAR ISI
Halaman

Halaman Sampul.........................................................................................................................i
Halaman Pengesahan...............................................................................................................ii
Daftar Isi......................................................................................................................................iii
Daftar Lampiran.......................................................................................................................iv
Ringkasan......................................................................................................................................v
BAB 1. PENDAHULUAN......................................................................................................1
1.1 Latar Belakang......................................................................................................................1
1.2 Rumusan Masalah................................................................................................................2
1.3 Tujuan......................................................................................................................................2
1.4 Luaran yang Diharapkan...................................................................................................2
1.5 Kegunaan................................................................................................................................2
BAB 2. TINJAUAN PUSTAKA...........................................................................................2
2.1 Malaria serebral.....................................................................................................................2
2.1.1 Histopatologi Otak....................................................................................................3
2.2 Zingiber cassumunar............................................................................................................4
2.2.1 Klasifikasi....................................................................................................................4
2.2.2 Kandungan Bahan Aktif Zingiber cassumunar...............................................4
2.2.3 Manfaat Zingiber cassumunar...............................................................................4
2.3 Brain Derived Neurotrophic Factor (BDNF)................................................................4
BAB 3. METODE PENILITIAN.........................................................................................4
3.1 Rancangan Penelitian...........................................................................................................4
3.2 Sample Penelitian..................................................................................................................5
3.3 Variabel Penelitian................................................................................................................5
3.4 Alur Kerja Penelitian............................................................................................................6
3.5 Prosedur Penelitian...............................................................................................................6
3.5.1 Ekstraksi Bangle (Zingiber cassumunar)..........................................................6
3.5.2 Perlakuan pada Hewan Coba................................................................................7
3.5.3 Pemeriksaan Kadar BDNF Darah dengan ELISA..........................................7
3.5.4 Pembuatan dan Pewarnaan Preparat Histopatologi........................................7
3.6 Analisis Data...........................................................................................................................8
BAB 4. BIAYA DAN JADWAL KEGIATAN..................................................................8
4.1 Anggaran Biaya
............................................................................................................. 8
4.2 Jadwal Kegiatan....................................................................................................................8
DAFTAR PUSTAKA................................................................................................................9
LAMPIRAN...............................................................................................................................11

4.2 Jadwal Kegiatan


No
1
2
3
4
5
6

Kegiatan
Pengumpulan
Zingiber Cassumunar
Ekstraksi Zingiber
Cassumunar
Pembelian,
Pengkodisian hewan
Uji
Perlakuan hewan uji
Hasil dan evaluasi hasil
Laporan akhir dan
publikasi

Bulan ke3

DAFTAR LAMPIRAN

Lampiran 1.
Lampiran 2.
Lampiran 3.
Lampiran 4.

Biodata Ketua, Anggota, dan Dosen Pembimbing,


Justifikasi Anggaran Biaya
Susunan Organisasi Tim Kegiatan dan Pembagian Tugas
Surat Pernyataan Ketua Peneliti/Pelaksana

Halaman
11
18
21
22

iv

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