Rx
Pilocarpine nitrate 0.3g
Sod. Chloride
q.s.
Purified Water
30ml
Make isotonic solution
= MWNaCl x
i med
iNaCl
MWmed
E=0.23
0.3g in 30ml
c in 100ml
c = 1%
NaCl
c% = % strength of
medicament
c% = % strength of
medicament
= 0.67% w/v
0.67g in 100ml
b in 30ml
Sod. Chloride = 0.201g
Cl -
Na-
Mg2+
K-
Ca2+
Example
A 200ml volume of a 2% solution of glucose for IV
injection is to be made isotonic by the addition of NaCl.
Stock Available
Example
w = 0.52 (2 x 0.1)
Rx
Prepare 500ml of
12.5% Dextrose
0.576
So, NaCl required = 0.56g x 2
= 1.1g
Answer
Example
Rate =
V(ml)
Time(min)
= drops
Time(min)
= V(ml) x Drip set (drops/ml)
Time(min)
1.5
1.5mg
/ml
0 mg/ml
100mg = 500ml
2mg
y
10ml = 1 min
500ml
z
23.5
z = 50min
Acyclovir
1.5 = x ml
23.5 500ml
Example
1. 100mg of metaraminol are added to 500ml of
saline infusion. What should be the rate of
infusion to give a dose of 2 mg per minute?
How long will the infusion take?
D10
500ml
31.9mL
NS
500
ml
Vfinal=531.9ml
D50
1.
2.
3.
D50
1.
1500ml for first 20 kg + 20ml/kg,
for wt beyond 20kg.
(Vfinal ml)
BMI= kg2
m
Health BMI=18-25
= 25kcal/kg/day
2.
1 cm = 0.01m
= 0.4 inch
1000mg
23.23mmol
in
100ml
Answer
Vfinal = 2400ml
BMI = 23
Wt used = 65kg
Protein
369.75 kcal
92.44 g
CHO
1109.25 kcal
326.25 g
Lipid
739.5 kcal
82.17 g
462.2ml
385.2mOsm/L
652.5ml
679.69mOsm/L
410.8ml
51.35mOsm/L
65
Ca2+
65mmol
130mEq
24
Stock Available
279.8ml
108.3mOsm/L
2218.51
100
Electrolyte
Ca2+ = 1 mmol/kg/day
326.25
92.44
82.17
594.7ml