Skin

undergoes

Loss of
skin
elasticity

Signs and
symptoms:

Difficulty
of eating
Pain
upon
swallowi
ng
(pain
scale: 8
out of
10)
RR= 10
cpm
CR= 110

Tissue
degenerat
es and
becomes

Esophageal
dysfunction

Signs and
symptoms
:

Clubbin
g of
nails
Pale nail
beds
Low
capillary
refill (3

Aggregation
of
collagenous
material in
the intimal
lining of

Narrowing
and
thickening of
blood
Microvascula
r obstruction

Decreased
tissue
perfusion

Calcium
deposits on
skin

Small hard ,oval white

skin lesions.
Pain

Smooth
muscles
becomes
over
sensitive to

Increased
vasoconstric
tion in
response to
cold/stress

Raynauds
phenomenon
occurs

Hypoxia

Increased
influx of
calcium ions

Signs and symptoms:

Damages
the

Blood
vessels
becomes
less

Blood flow is
compromise

Calcinosis

Legend:
Pathological process.

Signs & Symptoms of decreased tissue perfusion

Signs & Symptoms of esophageal dysfunction.

Signs & Symptoms of Calcinosis.

Signs & Symptoms of increased collagen in skin.

Serological tests.

Signs & Symptoms of increased collagen in joints.

Precipitating factors.

Predisposing factors.