DAFTAR ISI

Halaman
HALAMAN JUDUL

HALAMAN PENGESAHAN

ii

DAFTAR ISI

iii

DAFTAR GAMBAR

vi

DAFTAR TABEL

vii

BAB I PENDAHULUAN...................................................................................
A
B
C
D

Latar Belakang Masalah...................................................................

Perumusan Masalah .........................................................................
Tujuan Penelitian...............................................................................
Manfaat Penelitian............................................................................

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3
4
4

BAB II TINJAUAN PUSTAKA.........................................................................

A Tanaman Kayu Manis (Cinnamomum burmanni Nees ex BI.).........

1 Sistematika tanaman....................................................................
2 Nama daerah................................................................................
3 Kegunaan tanaman......................................................................
4 Kandungan kimia........................................................................
B Tanaman Pepaya (Carica Papaya L.)...............................................
1 Sistematika tanaman....................................................................
2 Nama daerah................................................................................
3 Kegunaan tanaman......................................................................
4 Kandungan kimia........................................................................
C Ekstraksi............................................................................................
1 Pengertian ekstraksi....................................................................
2 Pelarut.........................................................................................
D Hewan Percobaan..............................................................................
1 Sistematika tikus putih................................................................
2 Karakteristik................................................................................
3 Jenis kelamin...............................................................................
E Landasan Teori..................................................................................
F Hipotesis............................................................................................

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BAB III METODE PENELITIAN...................................................................... 28

3

A Populasi dan Sampel.........................................................................

B Variabel Utama..................................................................................
1 Identifikasi variabel utama..........................................................
2 Klasifikasi variabel utama...........................................................
3 Definisi operasional variabel utama............................................
C Alat, Bahan, dan Hewan Percobaan..................................................
1 Alat..............................................................................................
2 Bahan...........................................................................................
3 Hewan Percobaan........................................................................
D Jalannya Penelitian............................................................................
1. Determinasi tanaman...................................................................
2. Pembuatan serbuk........................................................................
3. Penetapan susut pengeringan.......................................................
4. Pembuatan suspensi ....................................................................
4.1. Larutan CMC 0,5%..............................................................
4.2. Suspensi simvastatin.............................................................
5. Pembuatan ekstrak etanol 96% kulit kayu manis........................
6. Pemeriksaan bebas alkohol..........................................................
7. Pembuatan ekstrak air daun pepaya............................................
8. Identifikasi senyawa....................................................................
8.1. Uji alkaloid...........................................................................
8.2. Uji saponin............................................................................
8.3. Uji flavonoid.........................................................................
8.4. Uji senyawa fenolat (Tanin) ................................................
9. Pembuatan pakan diet tinggi lemak.............................................
10. Perlakuan terhadap hewan uji......................................................
11. Penetapan dosis sediaan..............................................................
12. Prosedur kerja perlakuan hewan uji............................................
13. Penentuan kadar HDL dan LDL serum darah tikus.....................
E Analisis Data.......................................................................................
F Jadwal Kegiatan Penelitian.................................................................

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DAFTAR PUSTAKA.......................................................................................... 42