68 Registration No. : Centre of Exam. ‘QUESTION PAPER SERIES CODE A Name of Candidate + Signature of COMBINED ENTRANCE EXAMINATION, 2014 M.Tech. BIOTECHNOLOGY INSTRUCTIONS FOR CANDIDATES ‘Tae Question Paper consists of two Sections. Section—I is for those opting for oe Stream and Section—ll is for those opting for Science Stream. Depending updk J ‘grounds, candidates are required to attempt questions from ONE of the Sections ot ‘SECTION—1 TECHNOLOGY /ENGINEERING STREAM ( Part—A, Part—B, Part—C ) [ Field of Study Code : MTB } Time Allowed : 8 hours J cm Marks : 120 Candidates must read carefully the following instructions bef ping the/ Question Paper {) Wate your Name and Registation Number inthe spa eS urpose on the tp ofthis eon the Anewer She. Question Paper and in the Answer Sheet (i) Please darken the appropriate Circle of Question Ps (ii) The Question Paper is organized and answers are val(ed Ss Part—A Basic Engineering and Technology in macology {Marks : 45) Answer any 45 questions out of Note: (In case any candidate answers the required 45 questions, the first 45 questions attempted will by Part—B : Physics, Chemistry ang-Mat rks : 40) Answer all questions Part—C : Fundamentals of Life Seigces formatics (Marks : 95) Answer all questions Gv) Each question caries I mark. The tive marking and ¥ mark will be deducted for each wrong answer. law (¥) Answer the questions in the Ans (a) or (b) oF (c} or (¢) (as the (vi) Answers written by the (vii) Calculators and Loy (vill) Pages at the end ha Gr Rough Work, (ix) Return the Question *r Sheet to the Invigilator at the end of the entrance examination. DO a fs provided separately by darkening the correct choice, ie., bg) against each question in the corresponding circle. ‘the Question Paper will not be evaluated L. Use only Blye/ Ipoint Pen (do not use Pencil) to darken the appropriate Circle. 2. Please darken the\Yipole Circle 3. Darken ONLY ONE CIRCLE for each question as shown in example below Wrong | Wrong | Wrong | Correct @|GHOO|FOOG|OHOO|OOC® 4 change in the answer is allowed. Ph ni ce any stray marks on the Answer Sheet. leas?~ ‘This would represent what type of drug delivery? (a) Parenteral and local (b) Parenteral and syst {c) Enteral 6) (@)_ Enteralanthyys ¢) 81. The vn may b 1g modified to produce amoxicillin by attaching a/an O ° cn. ° gat dv sen, NH N. 00H b 4 ‘group (b) Nanitie Kee hydroxyl group and carboxylic group (68—-LA 2082. A patient has a serum potassium level of 6 mmol/L. The amount of potassium in milligram in a 20 mL sample of the patient’s serum is (relative atomic mass of potassium = 39) (a) 3-08 mg NR (b) 468 mg (ec) 308 mg {d) 468 mg 83. What is the unit of area under the plasma concentration-time © ic (a) mgt {bo} mgi7hr © (@) mgiMar! WG 84, Lignocaine has a pK, of 7-9 at pH 69. The kes fonized is (a) 5% (10% (50% (90% 85, Find out from the graph, wl rect about drug X, ¥ and Z. x oy z ° 8 z ° Tog dose ( lost potent and efficient drug potent and efficient drug the most potent and efficient drug /X and Z are both equally potent and efficient drugs 168A 21 [P.T.0.86. Indicate the anesthetic which is used intravenously. {a} Propofol (b) Halothane NS (c]_ Desflurane (a) Nitrous oxide 87. Select the drug which inhibits peristalsis. (a) Castor oil {b) Bisacodyl ) {c) Loperamide @ (@) Sorbitol 88. “Which of the following substances is synthesizgt\ witht vessel walls and inhibits thypmbogenesis? (a) Thromboxane Ay (TXA} (b) Prostacyclin (PGI) (c) Prostaglandin (PGE) (@) Misoprosto! 89. Indicate the drug rionsfe (gonists of heparin. (@) Aspirin (bo) Dicume co) ma (4) Protamid@sullate Oo 90. The je positive inotropic drug is dobutamine ) digitoxin /68-1-A 22PART—B. ( Marks : 40 ) { Physics, Chemistry and Mathematics ) RS Answer all questions 91. As a planet orbits the sun, which of the following must remain const fa) Velocity (b) Angular momentum 7 (c}_ Gravitational force (4) Radius of the orbit 92. An electric field can deflect e fa) X-rays ; (b) a-particles {)_ neutrons (a) rays 93. The horizontal range of a proj 2 whén the angle of projection is 30°. The value of another angle of projection forthe \aayhe range is (a) 60° (0) 50° (45° (@) 30° 94. A satelitets Goving und the earth, In order to make it move to infinity, its speed must, be incre Oo ( RS not possible to do so factor of 2 (681A 23 [P.T.O.95. A bullet is fired from a gun. The gun recoils, The KE of the recoil will be (a) greater than the KE of the bullet (b) equal to the KE of the bullet ()_ less than the KE of the bullet (a) four times that of the KE of the bullet re ground in 96. An object is projected upwards with a velocity of 100 m/s. It approximately (g = 10 m/s”) KS f@ 10s (b) 20s 15s AWS (@ 5s S 97. Two particles A and B initial it 7 ards each other under a mutual force of attraction. At the instant fther eed of Ais Vand the speed of Bis 2V, the speed of the centre of mass of the stem (a) zero o) Vv (ESV (4) 3v ° 98. During the mete of a slab of ice at 273 K at atmospheric pressure & ROsifive work is done by the ice-water system on the atmosphere \o the internal energy of the ice-water system increases (i) the internal energy of the ice-water system decreases work is done by the ice-water system on the atmosphere 168—-LA 2499. Ice starts forming in a lake with water at 0 °C when the atmospheric temperature is - 10°C. If the time taken for 1 cm of ice to be formed is 7 hours, the time taken fort thickness of ice to change from 1 cm to 2 cm is (@) 7hr (b) <7hr () > 14hr (@) > 7 hr but <14 hr a 100, An open pot is filled with air at 60 °C. What is the temperati heat so that th. part of this air goes outside? fa) i71°c tb) 100°e 0 (a) ~73°C 101. A litre of an ideal gas at 27 approximately equal to \eagechat constant pressure to 297 °C. Final volume is (a) 1-2 litres (b) 1-9 litres (c) 19 litres 102. A gas at 300K, enclosed in a container, is placed in a fast-moving train. When the train is in motion, the jWnperature of the gas (@) = e300 K ins unchanged becomes unsteady /68—1-A 25 [P.T.0.103. A man inside an artificial satellite feels weightlessness, because the force of attraction due to the earth is (a) zero at that place {b) balanced by the force of attraction due to the moon () equal to the centripetal force (@) non-effective due to particular design of the satellite 104. A thermodynamic cycle of diesel engine works at (a) constant pressure (b) constant volume S [c) constant temperature @ (a) constant heat 105. Two point charges q, and qo are separated by gdistadiee ;/What happens to the force on qq) if the charge on q, is doubled? {a} It is doubled oe Y {c) It is quadrupled {d) It becomes ‘th of the o1 106. Refractive index of materi oximately equal to square root of a) electrical permi {b) magnetic ()_ electridah pernittivity X-ragnetic permeability (@)_electgicat Reg jty magnetic permeability 107. Amo Ging acids, which has the lowest pXq value? H een CH,CH,COOH /68—-A 26108. 109. 110. ‘The highest electrical conductivity of the following aqueous solutions is of (a) 0:1 M acetic acid (b) 0:1 M chloroacetic acid (6) 0-1 M fluoroacetic acid (2) 0-1 M diftuoroacetic acid Which type of isomerism is shown by 2,3-dichlorobutane? (2) Diastereo (>) Optical e {c) Geometric Y (4) Structural . Which of the following is fully fluorinated SS (a) Neoprene (b) Teflon (6) Thiokol (@ pve octahedral complex with 111, How many EDTA (ethylened peri \cetic acid) molecules are required to make an fey) 2 @ si (b) Three {e) One ieee {d) Eight ° visible light has the highest energy? /68—1-A 27 [P.T.O.113... Of the following, which radiation has the longest wavelength and which radiation has the greatest energy? (a) Ultraviolet, gamma BR (©) Visible, ultraviolet (9) Gamma, gamma {d) Visible, gamma 114, What color of visible light has the longest wavelength? a S (b) Violet {e) Red @) (@) Yellow 115, Gold and platinum group metals are found in fatire iiypttallic form, because they are {a) solids at room temperature ee Y (©) telatively inert (@) relatively abundant 116, A mineral is (a) a solid inors .pOURG that contains one or more metals (b) a source fc) a metahin ith\elementsiorm (a) a trensitidg\ metal ion purpose of adding EDTA to prepared foods? Jes & ions such as Ca?* in solution so the foods look good eS Fe lla ‘To complex iron (Ill) ions so they can catalyze protein decomposition on cooking (4) To aid in browning of the surface during cooking /68—1-A 28118. A complex that absorbs light at 700 nm will appear (a) ted RS (b) green (o) yellow (4) orange 119, Ametal complex absorbs ight mainly at 420 nm, What is the colopa the cpmibiex? (a) Green (b) Yellow (o) Red 120. The attraction of a metal to a neutral ligan (b) hydrophobic interaction (c) _ ion-dipole interaction (d) dipote-dipole interactio: 121. Which of the following at can form rings, long yrotein structure that involves interactions between the side chains of the ther than the interactions between molecules within the backbone is 168A 29 [P.T.0.123. An amino acid has the form shown at — KR NH (a) a pH greater than its isoelectric point (b) a pH less than its isoelectric point (ec) any pH other than 70 ° (@)__ its isoelectric point S 124, Which one of the following microorganisms is come Qs iological indicator in autoclave? (a) Bacilius megaterium NMS (b) Pseudomonas aeruginosa S (c) Bacillus stearothermophilus Y (@) Staphylococcus aureus 128. Which pair of amino acids iopié interactions? (a) Glutamic acid and s =) (0) Glycine and aspétapin® () Leuci el @ as asin! ° 126. The sf wigtp protein primary structure is destroyed, thus destroying the other ary ») structure, is ied io) ~ esterified (4) hydrolyzed (68—-1-A 30127. Good sources of carbohydrate are WR (a) fats, oils, butter and margarine (©) fish, eggs, beef, pork and poultry (c) cereals, fruits, vegetables and milk (€)green-leafy vegetables, seafood and water C ° 128. Cooked starch is more digestible, because KS (a) it has been partially hydrolyzed during cooking @ (b) the amylopectin is converted to amylo: 2 akihg (@)_ the enzymes that hydrolyze the starch(&e tive when the starch is hot (4) the starch granules take up water, Ce more accessible to the enzymes 129. What are the selection rules xfTi® tion? fa) Absorption only occur rical molecules (6) Absorption only o dipole change (0) Absorption\tear vibrational quantum number (allot abo Oo 130. In what-region afplie spectrum does infrared radiation occur? energy end ) en te visible and ultraviolet regions tween the visible and microwave regions Between the visible and X-ray regions /68—1-A 31 [P.-T.0.PART—C ( Marks : 35 ) Re ( Fundamentals of Life Sciences and Informatics ) Answer all questions 131, ‘The respiratory quotient during cellular respiration depends upon (a) nature of substrate (b) nature of enzyme (c) amount of CO, released E ) {a) amount of oxygen utilized 132, Which blood vessel brings oxygenated blood? (a) Pulmonary artery (b) Right ventricle (©) Superior vena cava (4) Pulmonary vein 133. Sodium and potassium balance is r A) (a) aldosterone (0) testosterone () estradiol (4) cholesterol 194, If two black rappits GEepssed ten black and three white rabbits result. The parents are (a) homofgou! (b) het 8 (c) _ incogpletel)\dominant 338. sibling (4) phenocopy 168—1-A 32136. Loci carried on the same chromosome are called (@) alleles IN {b) non-allelic (9 linked (2) recombinants 137. Trisomy 21 is also referred to as Oo (a) Edward’s syndrome {b) David's syndrome ES (4) Patan’ syndrome YQ (a) Down's syndrome (a) phosphates S (b) antisense Y (nonsense (d) start codons: 139. ing genes can be obtained from (b) SNP (9 retrovis (@) RFLP O° 140. In whieg following, recombination does ‘not occur? es igh »phila males (d)/ Drosophila females (68-1-A 33 [P.T.0.141, Cancer drug methotrexate (a) inhibits dihydrofolate reductase Ro {b) inhibits meiosis (c) causes Byy deficiency (a) inhibits uric acid formation 142. Which of the following enzymes does aspirin inhibit? Oo (a) Dehydrogenase (b} Protease ()_Cyclooxygenase (4) Acetylase 143, Which of the following coenzymes is requir(@ for-qneéarbon transfer? (a) NAD* {b) FAD (c} Tetrahydrofolate (@) Biotin 144, Nitrogen in terrestrial Gap estar as @) ion id tol\aci O° amin (b) uric allant urea) pmmunity, the primary consumers are © () ) omnivores (a) detritivores /68—1-A 34146. The major plant hormone important in regulating plant's response towards salt stre (b) abscisic acid (6) gibberellin (d) cytokinin 147. Water loss through the stomata of leaves is termed as {a) transpiration Oo (b) translocation (c} osmosis KS {d) evaporation ¢ 248. The net number of ATP generated from one jpolegate.) oe by the process of glycolysis is fa) 16 ) 2 @ 8 (a) 32 Y 149. In the electron transport systé ‘ceptor of proton is (@) cytochrome b (0) cytochrome ay (6) oxygen {€) ubiquinone 150. Most vitaming fubgtion v) (a) tubricants\or adtive rt (b) 2 foundatioh\or bdilding bones (4) transport moldsles within plasma membranes (0 ) ol (@ co ° 151. wn ate from 0 aS issovers. ene flow nondisjunction /68—-L-A 35 {P.T.0.152. Which one of the following does involve genetic engineering? nea KR (bo) Deamination (4) Cloning (@) Mutation 183. T cells mature in the KS (a) thyfoid gland Y {b) spleen = SO (4) lymph nodes ee 154. Initiation of new strand of replication requires (a) DNA primer {b) RNA primer () RNA (a) DNA! oO 155. Plasmidg arq7) jreular DNA segments in bacteria .-replicating DNA molecules in bacteria made of RNA (a) necessary for bacteria to reproduce 168A 36156. What protocol is used for file transfer? (a) TELNET (ob) FTP RB (HTTP (a) UDP. 157. The UNIX command used to search files for lines matching a regular expreseion is called as oO (a) sort (>) grep jose Y (search 188. TCP/IP protocol used for remote terminal copffiBbtion ypevice is (a) TELNET @ (o) FIP (o HTTP (@) UDP 159, The Linux command grep ee wt (a) join two files txt (0) search the\Ne ines containing the text string gccatg (6) append he texk gccaths6/ina. txt (a) overwpite dna txtvith gecatg 160. The I Gana used to count the number of chafacters in a given file is (68—1-A 37 [P:T.0,161. The Linux command used to convert a group of files into an archive is fa) find () cat IS () tar (a) grep 162. A device used to forward data packets between computer networks and operajy6 at the OSI model network layer is (a) router (b) connector 163. The internet protocol for sending e-mail m: S “ {bus éy (d)_ bridge SS fa) FTP () HTTP (SMTP (4) TELNET 164. The SQL command used privileges on a given database objects to the users is Ss (2) revoke (b) grant, () comm’ {d) update 165. Th Sfand Select * from protein where pdbid = 2apl will display i columns which are having pdbid 2apl a thy Yecords of the table protein all the records which are having a * symbol )) all the records which are having pdbid 2apt /68—1-A 3868 eee (cal I | QUESTION PAPER Centre of Exam. : _ ‘SERIES CODE A Name of Candidate : Signature of COMBINED ENTRANCE EXAMINATION, 2014 M.Tech. BIOTECHNOLOGY INSTRUCTIONS FOR CANDIDATES ° SECTION—II SCIENCE STREAM ( Part—A, Part—B, Part—C ) [ Field of Study Code : MTB } Time Allowed : 3 hours sum Marks : 120 Candidates must read carefully the following instructions before attemy{ pf the) piestion Paper (i) Write your Name and Registration Number in the space provided fo) se on the top of this Question Paper and in the Answer Sheet. lil) Please darken the appropriate Circle of Question Pa| the Answer Sheet. (ii) The Question Paper is organized and answers are valued xg YQllo Part—A : Life Sciences (Marks : 50) Answer any 50 questions out of 60 q Note: (In case any candidate answers Tag thY required 50 questions, the first 50 questions attempted will be ) Part—B Physics and Chemistry (Marks Answer all questions Part-C : Mathematics, Compu Answer alll questions fix) Bach question carries 1 mark. There each wrong answer. (Answer the questions in the Ang(érShQyt vided separately by darkening the correct choice, ice, (a) or {b) oF () oF (a) (as the efh ba) against cach question in the corresponding circle. ation Sciences {Marks : 30) galive marking and ¥. mark will be deducted for (vi) Answer written by the candig the Question Paper will not be evaluated. (vi) Calculators and Log Tabley-tex, Dewar (viii) Pages at the end fe prdpided for Rough Work. (ix) Return the Questios x 2. Please daGBen We\ghole Circle 3. Darkep ONLY ONBICIRCLE for each question as shown in example below e Wrong Wrong Wrong Correct @|FOHOO|POOE|OOO8|O@HOO 4 }0 change in the answer is allowed. Pl Ropfnake any stray marks on the Answer Sheet. leape don't do any rough work on the Answer Sheet. your answer only in the appropriate space against the number corresponding to the restion, 8 )Fasure that you ha ‘the Answer Sheet. darkens the appropriate Circle of Question Paper Series Code on (681A [P.T.0.SECTION—I (SCIENCE STREAM } PART—A KR ( Marks : 50 ) { Life Sciences ) Answer any fifty questions 1. An allele is best defined as (a) an alternative form of gene S {b) the position of a gene on a chromosome {¢) a cellular structure composed of DNA and protein @) (d) the place on a chromosome where spindle fibres att a 2. Upon which two major features of chromosomes depend? ‘ological identification (a) Length of chromosome and position of (>) Amount of DNA and intensity of st ff (c) Numbers of nucleoli and centro (@) Number of chromatids angen, If an individual of genotype AaB] re iNjeferossed, how many different phenotypes can appear in their offspring? 3 © 6 @ 8 (a) 16 UAG is described as fen used to induce polyploidy experimentally in plants is /68—0-A 43 {P.T.0.6. If during synapsis a certain kind of abnormal chromosome is always forced to bulge away from its normal homologue, the abnormality is classified as (2) an inversion IS (b) a duplication: {ce} an isochromosome (d) a deficiency 7. If four chromosomes synapse into @ cross-shaped configurasign during meiotic prophase, the organism is heterozygous for a (a) pericentric inversion ers psciaa Y (@) paracentric inversion 8. The physiologically receptive state in which ter ill is able to be transformed is called (a) sensitized Y (b) activated {c) competence (4) lysogenic 9. The distances between lgenes, as determined from interrupted conjugation experiments, are mga, its of (a) morgan’ {b) nucledtide\Pairs (minute (@ migdmet oO Ke correct, statement on stability of nucleic acids. Ke js Jabile in alkali but DNA is not (BNA ¥ labile in alkali but RNA is not Both RNA and DNA are labile in alkali 10. (a) Neither RNA nor DNA is labile in alkali /681-A 4411. 12. 13. 14. 18. 16. /68—1-A 45 Restriction-modification systems of bacteria exist to a) protect bacteria from invading foreign DNA {c) help the bacterial chromosome replicate {d) promote complementation ‘Among all known phages reproducing vegetatively, the only one that nejthec killy Aor lyses its host cell is (a) M13 ) 14 (9 Mu @ PL Bacterial cells are rendered more permeable to uptake fa) heat (b) calcium chloride () alkali (@) ultrasound ‘The melting temperature of a BNA pele: Actermined by using (a) electrophoresis (b) change in electrical conch {)_spectrophotometric stp (a) ultracentrifugation Which of the fog ¥)fesentiates eukaryotic DNA replication from prokaryotic replication?, (a) Muttiphe\gri (b) Bidirectio tion forks (0 Use Ponty\Qye DNA polymerase a) of @NA primer jerprinting process involves FLPs chain termination 4) cDNA [P-T.0.17. Hormones are thought to regulate gene activity primarily at the level of (a) transcription Ro {b) mRNA processing (9 translation (@) post-translation processing of protein 18. Which of the following molecules moves regularly from the nucleusio the eesplasmn? (a) Glycogen (b) RNA (e) DNA (a) Cholesterol 19. DNA migrates in an electric field, because SS (a) it is positively charged (b) it is negatively charged @ ) () it carries both negative-and plgitivechatg {@)_ it is neutral es at different locations 20. Which of the following is; Cy tercellular junction between animal cells? (a) Middle tametta b) (e) Plasmodéeyna (c) Des me (a) oN O° ) Simple diffusion f) Sodium-potassitim pump /68—1-A. 4622, How many carbon atoms are in an oxaloacetic acid molecule, which join with an acetyl group step I of the Krebs citric acid cycle? @ 2 IN 3 fb} i) 4 id) 6 (0) cytochrome a3 {o) oxygen’ 23. In the electron transport system, the final acceptor of proton is O (a) cytochrome b KS (@) ubiquinone (b} intermembrane space 24, The place in the mitochondrion where the pHi lowesi/s the (a) ribosomal complex 2 {e) cytosol (4) matrix 25. In a eukaryotic cell, glycol 5 ‘place (a) within the nucl (0) on the rodgh & reticulum (c)_ in the Sieplay, budledtside the organelles (a) withip,the\Qajtocondria 26. billion years 500 million years /68—1-A 47 [P.T.0.27. An isolated population of humans with approximately equal numbers of blue-eyed and brown-eyed individuals was decimated by an earthquake. Only a few brown-eyed people remained to form the next generation. This kind of change in the gene pool is calle: (a) Hardy-Weinberg equilibrium (b) blocked gene flow (6) bottleneck effect (d) founder effect ° 28, The regions of an antibody that determine its general role or eff ion, are its (a) variable (V) regions {b) constant (C) regions {c) mutated (M) regions (a) bifurcated (B) regions NS Lymphocytes that activate B cells and T c (a) activator B cells (b) cytotoxic T cells (macrophages (a) helper T cells 30. An allergic reaction is (ey) antibodies of the SZ a) IgG groy fb) IgM grou; {Tea gre {d) IgE@roup) le) 31. s of an allergic reaction develop in response to NS. KS rk ins S . histamine (d) complement (68-ILA 4832, The virus that causes acquired immunodeficiency syndrome (AIDS) parasitizes (a) B cells {b) cytotoxic T cells {o) helper T cells (@)_ the membranes of lymph nodes 33. White blood celis that are non-specific killers of microbes are (2) B cells S 7 i phacnyte KS (ce) killer T cells Y (a) helper T cells (a) lubricants for active transport {b) 4 foundation for building bones () transport molecules witifin piésina ranes (4) coenzymes 35. About how many nephrot re in each kidney of a human? fa) 160 {bo} 2000 fe) 10000) @ 1 0 Ce ‘Sowing statements is not true? UeRatype determines phenotype 36. Whi (DQ pneipspe is the physical appearance of a trait in an organism yhenotype determines genotype j Alleles are different forms of the same gene /68—1-A. 49 [P.7.0.37. A large rise in body temperature of a human is corrected mainly by (a) constricting the skin arteries and sweating (©) constricting the skin arteries and shivering (c) dilating the skin arteries and sweating (@) dilating the skin arteries and shivering 38. The wobble effect is the (a) lack of precision in pairing with regard to the third base in the\coddy/and anticodon (b) instability of the DNA molecule when unwound ° (©) instability of pairing when a purine pairs with another (@) undulating movements of mRNA 39. The Northern technique involves (a) the detection of RNA fragments on membranes by sbeffic :\dfoactive DNA probe (b) the detection of DNA fragments on membré foactive DNA probe (c)_ the detection of proteins on membranes a Padjéactive DNA probe (@) the detection of proteins on membraneg“Ysin3\Spetific radioactive antibodies 40. Restriction endonuclease generated DNA frazmefit3)separated by gel electrophoresis and blot transferred onto a membran¢—fHte probed with a radioactive DNA fragment. This procedure is called (a) gene cloning (b) the Souther technigu ()_ the polymerase chain rei (d) recombinant DNA 41, ‘Gene library’ is a term, (a) a computerize jown DNA sequences (b) faining DNA fragments representing the majority of the ati plant or animal © ooks\UBdut recombinant DNA technology (a) 1e amino acid sequences of protein coding genes 42, One significant discoveries, which allowed the development of reco! technology, was (a) overy of antibiotics used for selecting transformed bacteria dentification and isolation of restriction endonucleases permitting specific ring the discovery of DNA and RNA polymerase allowing workers to synthesize any ws somuenee the development of the polymerase chain reaction /68—1-A so43. A key feature of insertional mutagenesis for the identification of plasmids containing recombinant DNA is (a) the production of nutritional auxotrophs {b) the DNA sequencing of recombinant plasmids (the production of restriction endonuclease maps of recombinant plasmi (@) the disruption of a gene on the plasmid by the serted recom 44, Ifa particular DNA molecule has 20% adenine (A), what is the percentage o} € (C) in the same molecule? fa) 10% ° (b) 20% (@) 40% 45. Bacterial resistance to antibiotic is a genetic fhe bacterial (a) plasmid (b) chromosome {) intron (4) centromere 46. Klenow fragment of DNA Pol((lacf3 which vf the following activities? (e) 5’ +3" exonuclease (b) 3’ 5’ exonuclease (5+ polymerase (@) 3°45" polymer 47. (a) {b) ©) /68—1-A 51 [P.-T.0.49. Which of the following are not found in DNA binding protein? (a]_Homeodomains (c) Leucine zippers (a) CpG islands 50. The strength of a typical hydrogen bond in DNA is about (a) 2-3 kcal/mole (b) 10-15 kcal/mole O° () 23ev @ is 5-10 eV 51. The unique property of the Taq DNA polymerase enzyme| the polymerase chain reaction is {a} processivity (b) ability to make phosphodiester bonds E lutely essential for (c) ability to repair mistakes (4) thermostability 52. The polymerase chain reactioy 8 n (a) cutting DNA into many Bm (b) allowing restriction enzynfNQxcut 'ONA at palindromes (6) ° creating recombinant, (4) making many copii i! amount of DNA 53. Of the 64 codddg, de for amino acids? (a) 20 (bo) 22 © 30 @) 6 oO 54. Jan hormone produced by recombinant DNA technology was esi me G en insulin /68—1-A 5255. 56. 87. 88. 59. 60. (681A 53 Which of the following statements is incorrect in the context of CpG island? (a) - It frequently occurs in the promoter regions of mammalian genes (b) A large number of mammalian genes have CpG islands Ro () The G residue is generally methylated at position 5 (@) It has often been associated with cancer and aging In SDS-PAGE, the proteins are separated according to their {a) charge density ° {b) amino acid composition aaa S {d) isoelectric point ©) Which one of the following amino acids has only one ct (a) Glycine (b) Alanine (c]_ Arginine (a) Methionine In DNA replication, the helix is unwoGnd ich type of enzyme? {a} Topoisomerase (o} Primase (c) DNA polymerase () Helicase DNA from degradation by restriction endonucleases by 2 iée after formation from the genome 1A at the sites that the enzyme recognizes’ yy restriction endonucleases [P.T.0.61, 62. PART—B ( Marks : 40 ) ( Physics and Chemistry ) Answer all questions As a planet orbits the sun, which of the following must remain con: {a} Velocity oO (b) Angular momentum (co) Gravitational force < (a) Radius of the orbit When yellow light is incident on a surface, fel €mitted while green light can emit. If red light is incident on the surfate, then {a) no electrons are emitted (b) photons are emitted (c)_ electrons of higher energy are emitted (a) electrons of lower ener ted The horizontal range of @ ps ,, when the angle of projection is 30°, The value same range is (2) 60" {b) 50° (45°65. A bullet is fired from a gun. The gun recoils. The KE of the recoil will be (a) greater than the KE of the bullet BR {>) equal to the KE of the bullet {c) less than the KE of the bullet (a) four times that of the KE of the bullet fe) 66. An object is projected upwards with a velocity of 100 m/s. It fe ground in approximately (g = 10 m/s?) fe) 108 ) 205 ( 158 @ 58 67. Two particles A and B initiallysat pQgt, MOVE towards each other under a mutual force of attraction. At the instakt w} speed of Ais V and the speed of Bis 2V, the speed of the centre of mass ONT sys! (@) zero ov () sv (@ 3v : ° : 68. During the melting\bf a slab of ice at 273 K at atmospheric pressure jork is done by the ice-water system on the atmosphere s ork is done by the ice-water system on the atmosphere je internal energy of the ice-water system increases \ Q vy the internal energy of the ice-water system decreases /68—I-A 55 [P.T.0.69. Ice starts forming in a lake with water at 0 *C when the atmospheric temperature is 10°C. If the time taken for 1 cm of ice to be formed is 7 hours, the time taken for the thickness of ice to change from 1 cm to 2 cm is (a) Thr (ob) <7br (> 14¢hr (@) > 7 hr but < 16 br ° 70. An open pot is filled with air at 60°C. What is the tempfrature 8iheating so that vath part of this air goes outside? fa) 171°C (&) 100°C ( orc (a) 73°C 71. A litre of an ideal gas at 27 “Kis at constant pressure to 297 °C. Final volume is approximately equal to fa) 1-2 litres (b) 1-9 litres (9) 19 hit (a) zero 72. Agas at $00 K, Wlosed in a container, is placed in a fast-moving train. When the train is ion, @e temperature of the gas ve 300 K INS is 300 K remains unchanged (a) becomes unsteady /68—I-A 5673. A man inside an artificial satellite feels weightlessness, because the force of attraction 74. 75. 76. due to the earth is (a) zero at that place (b) balanced by the force of attraction due to the moon () equal to the centripetal force (4) non-effective due to particular design of the satellite A thermodynamic cycle of diesel engine works at (b) constant volume (@) constant heat ‘Two point charges q, and q are separated eS . What happens to the force ‘on dp, if the charge on q, is doubled? (a) It is doubled Y (©) It is halved (0) It is quadrupled (d) It becomes ¥éth of the ong (a) electrical permit {b) magnetic pextye: (electrical vity rm) fagnetic permeability (4) electriGal_penittivity/magnetic permeability ° /681-A 87 [P.T.0.78. Fast neutrons can easily be slowed down by (a) the use of lead shielding (b) passing them through water {c) clastic collisions with heavy nuclei (a) applying a strong electric field 79. A magnet moves into a coil of wire inducing a current in the wire. If the ma: ulled back out of the coil in the opposite direction as it went into thgcoil, whidH of the following will occur? fa) ‘There will be current produced in the coil in the same irectign #s before (b) There will be current produced in the coil in the o ingction as before {No current will be generated since the direction of (yftior))oMthe magnet cancels out (@)_ Instead of current being produced on HeQil(of Wie Zt will be produced on the magnet 80. An electric lamp is marked 220 V and 1 @)jesistance of its filament is fa) 484 ohm (b) 484 ohm (9 484 ohm (@) 0-484 ohm 81. Among the following a@a! has the lowest pK, value? (a) CHgoO fe) HCO (6) (CHg),CQQH (@ cufex,c ° 82. 7 (b) (a) (681A electrical conductivity of the following aqueous solutions is of tic acid loroacetic acid 0-1 M fluoroacetic acid 0-1 M difluoroacetic acid 5883. Which type of isomerism is shown by 2,3-dichlorobutane? {a} Diastereo RS {b) Optical () Geometric (4) Structural 84. Which of the following is fully fluorinated polymer? Se (@) Neoprene Y () Teflon (6) Thiokol MS (@ Pvc S 85. How many EDTA me molecules are required to make an octahedral complex with a Ca&¢/ion’ (a) Six (b) Three () One (d) Eight \ 86. What colo ng light has the highest energy? w ihe) ) Green /68—1-A 59 [P.7.0,87. Of the following, which radiation has the longest wavelength and which radiation has the greatest energy? {a) Ultraviolet, gamma BR (©) Visible, ultraviolet () Gamma, gamma {d) Visible, gamma 88, What color of visible light has the longest wavelength? (a) Blue ) (0) Violet @ {c) Red (a) Yellow ~~ 89. Gold and platinum group metals are found esy etallic form, because they are (a) solids at room temperature (0) highly reactive {c)__ relatively inert {d) relatively abundant 90. A mineral is fa) a solid fares \d that contains one or more metals 91 purpose of adding EDTA to prepared foods? ions such as Ca2* in solution so the foods look good Xe To complex trace metal ions that catalyze decomposition reactions fc) Tocomplex iron (Il ions so they can catalyze protein decomposition on cooking (@) To aid in browning of the surface, during cooking /68—-A 6092. A complex that absorbs light at 700 nm will appear (a) red SN (©) green MY (©) yellow (4) orange KS 93. A metal complex absorbs light mainly at 420 nm. What is the coloy 1e co@plex? (@) Green (b) Yellow (Rea (@) Orange Y 94. The attraction of a metal to a neutral may (@) ionic interaction S lectrons available for covalent bonding and wie bonds—making it the building block of the plecules? {b) hydrophobic interaction (©) _ion-dipole interaction {d) dipole-dipole interaction 95, Which of the following atoms has can form rings, long chain/anava ‘most versatile complex biol fa) Carbon ) () ° 96. The lev /68—1-A 61 [P.T.0.97. An amino acid has the form shown at oe (a) a pH greater than its isoelectric point (b) a pH less than its isoclectric point {o) any pH other than 7:0 {4)__ its isoelectric point x 98. Which amino acid can form covalent sulfur-sulfur =) (a) Phenylalanine {b) Cysteine : (¢) Proline (4) Methionine 99. Which pair of amino acids caljStae iohj/ interactions? a) Glutamic acid and (b) Glycine and asy {Leucine (a) Asparal lysi Oo 100, The state in wpe protein primary structure is destroyed, thus destroying the other aspe; ture, is Se 7 (eo) ( esterified (a) hydrolyzed /68—1-A 62PART—C ( Marks : 30) KR ( Mathematics, Computer and Information Sciences ) Answer all questions @ 101. If f(x)= =*—, O<.x sm /4, where xis measured in radians, then in this integV/as x is decreased, f(x) is (a) constant (ob) decreasing ()_ increasing (4) oscillating 102. If f(x) = x9 ~ 3x -2 in [-2, 3) by the ose) 5 then the value of C is fa) +vB RS ) 2/773 wo : &% 103. A tube is 3 such\eway that its edge is changing at a rate of 5 cm/s. If its edge is 4 theh the rate of change of its volume is 1poem?/sO) 2 Is. om" /s 240 em3/s /68—1-A 63 [P.7.0.104. The value of integral [*/ i x3sin4 xdx is fa) n/4 {b) 0 ( m/2 (@) 2m 105. The area bounded by the curve y=2x- x? fa) 9/2 sq. unit {b) 10/3 sq. unit Y (7/8 sq. unit (a) 5n/2 sq. unit © /68—1-A 64107. The vectors 2i~ 3, and ai + 5 are perpendicular to each other. Then the value a fa) -3 fb) 15/2 ) -5 @ 0 108. The differential equation y= xBeg 1 S fa) order 2, degree 2 iS (bo) order 2, degree 1 ) (0 order 1, degree 2 (a) order 1, degree 1 109, The integrating factor of differential eq eS = (tan! y- xjdy is fy? y (by) 110, tial equation SY =e 4 x2er¥ ig hy Ye-yre™ ec /68—I-A 65 [P.-T.0.qi. 112. 113. 114. 115. ‘The SQL command to modify the contents of records in a database table is a} change (b) update (o) modify (d) alter Which of the following are a set of data control language commapds in SQ] ° (a) Insert, Delete, Select {b) Drop, Alter, Create (c) Grant, Commit, Rollback YM () Delete, Commit, Create ‘The integrity of each entity in a database > ined through (2) primary key & (0) foreign key Y {c) duplicate key (4) Not null constraint In PERL programming k infalar values are stored in the following kind of variable (a) Arrays {b) Lists . =\C (@) Scaggs116. 117, lis. 119. 120. im Linux operating system, the output of one command can become the input of another command through (@) pipe Re (b) grep (©) listing (4) comm ‘The output of the Linux command grep “Atest” fl.txt is Oo {a) lines matching the pattern test in the file f1 xt (b) lines not matching the pattern test in the file fl.txt (c) lines beginning with the pattern test in the file @ {d) lines matching the pattern test in the file fl.sxt digplaypl along with the line number The following Linux command takes you to S ‘ectory from any directory in the system fa) cd (b) chd home (©) chdir home (@) home You can login and execute| cc Is in remote computers through fa) ftp () rtp () telnet (d)_ remotettp oO id€essing system that connects a domain name to a specified numeric {681A 67 [ P.T.O.tai. 122. 123. 124, ‘The number system which uses a positional notation with a radix of 2 is (a) octal (b) decimal (9 binary (d) hexadecimal The SQL command Select * from protein where pdbid = 2apl wiJ\display {a) all the columns which are having pdbid 2apl {b) all the records of the table protein ()_ all the records which are having a + symbol (a) all the records which are having pdbid/2apl ‘The SQL command to remove a record from/@stabl (a) Erase (&) Delete YM (Alter {d)_ Drop In relational model, dat ented in the form of a) entities and ps (b) objects {c) tables (a) netweprke Tunction used to find out whether two strings are identical is126. 127. 128. 129. 130. What will be the output of the following C program segment? for = 1; j <= 4; j++) printi"%d”, j); @) 4 (b) 123 @) 5 (a) 1234 ; Oo In C language switch-case control statement, case keyword will lowed by (a) float value (b) integer value (c) constant expression (@) character value WS In C language, the output of the expression fs I be fa) 0 - Y fo 2 (d) 3 In Java, the keyword used eis fa) this {b) upper {c) extends (a) inherit Oo In Jay used to define a class is tke /68—ILA 69 [P.T.0.