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ASCARIASIS

EVA HERENCIA PURBA / 13.005

MORPHOLOGY

DIFFERENCES BETWEEN MALE AND


FEMALE

Female produces 240.000 eggs per day


Eggs can survive up to 15 years in the

environmental (being extremely hardy and


resistant to extreme temperatures and
desiccation)
Adult worms can live in host for 1-2 years
Getting adult for 9-11 weeks after infective
from egg
Infestation starts by eating the egg and
making 2 infections:
Larva migration through the lungs
GI tract by adult worms

LIFE CYCLE

CLINICAL MANIFESTATION ON
LUNGS
Manifestation can be seen 1-2 weeks after

infective from egg


Can induce an intense reaction due to migration
causes and a dramatic inflammatory
hypersensitivity response to the antigens
Migration causes:
Burning substrenal discomfort
Fever
Cough

hypersensitivity response:
Wheezing
Dyspnea
Increase eosinophil
Those symptoms call as eosinophilic

pneumonitis
(may last for 2 to 3 weeks and usually resolve
spontaneously)

CLINICAL MANIFESTATION ON GI
TRACT
Intestinal obstruction on children -> colicky

abdominal pain and vomitting


A large bolus of entangled worms can cause
pain and small-bowel obstruction

MANIFESTATION ON OTHER ORGAN


SYSTEM
Hepatobiliary and pancreatic ascariasis in

common adult

DIAGNOSIS
Microscopic examination of sample feces for

characteristic thick-shelled eggs


Increased eosinophil on blood test
Eosinophilic pnemonitis -> larva can be seen
on sputum test
Cannot diagnosed on identifications of ova in

feces because adult worms havent yet mature


to produce eggs

TREATMENT
Albendazole 400 mg once
Mebendazole 100 mg bid for 3 days
Ivermectin150-200 mikrogram/Kg once
Inhibits cytoplasmic microtubule formation

PREVENTION
Improvement of hygien
Drink aintihelmintic medication once for every

6 months such as albendazole or


mebendazole.

SOURCES
18th Edition Harrison Internal Medicine
Goldman-Cecil Internal Medicine