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Math1010

DrugFilteringLab

Thepurposeofthislabistocomeupwithacontinuousmodelforexponentialdecay.

Dotassumesthatherkidneyscanfilterout25%ofadruginherbloodevery4hours.Sheknows
thatshewillneedtotakeadrugtestforaninterviewinacoupleofdays.Sheplansontakingone
1000milligramdoseofthedrugtohelpmanageherpain.

1.) Fillinthetableshowingtheamountofthedruginyourbloodasafunctionoftimeandround
eachvaluetothenearestmilligram.Thefirsttwodatapointsarealreadycompleted.

TIMESINCE
TAKING
THEDRUG(HR)
0
4
8
12
16
20
24
28
32
36
40
44
48
52
56
60
64
68

Whatmightamodelforthisdatalooklike?
y=a(1r)^t/4

AMOUNTOF
DRUG
INHERBLOOD
(MG)
1000
750
563
422
317
238
178
134
100
75
56
42
32
24
28
14
11
8

2.) Useagraphingutilitytomakeaplotoftheabovedata.Labelaxesappropriately.

3.) Basedonyourgraph,whatcanyousayaboutthedata?Forexample,isthereapattern?Is
thereconstantslope?Thereisaconstantslope,andthatisitbeingnegative.Itsaconstant
downwardslope,andthepatternisthatitloses25%ofitsvalueevery4hours.

4.) HowmanymilligramsofthedrugareinDotsbloodafter2days?32milligramsareleftinDots
bloodafter2days.

5.) HowmanymilligramsofthedrugareinDotsbloodafter5days?After5daystherewillbe.2
milligramsleftinDotsbloodofthedrug.

6.) HowmanymilligramsofthedrugareinDotsblood30hoursaftershetookthedrug?Explain
yourreasoning.Therewillbe117milligramsofthedruginDotsbloodafter30hours.The
reasoningbehindthisisthat30hoursishalfwaybetween28and32bothbeingpointsonthe
graphalready.Halfwaybetweenbothofthosepointswouldbe117,or12.5%oftheprevious
number.

7.) Abloodtestisabletodetectthepresenceofthisdrugifthereisatleast0.1mginapersons
blood.Howmanydayswillittakebeforethetestwillcomebacknegative?Explainyour
answer.Thefirsttimeitwillbebelow.1milligramwillbeafter5daysand8hours.ThewayI
cametothisansweristhatIwentthroughthegraphcontinuallyuntilIcametolessthan.1,
andthatwasat128hours.128hoursbeing5days8hours.

8.) Willthedrugeverbecompletelyremovedfromhersystem?Explainyourreasoning.What
complicationsmightarisefromhavingexcessamountsinhersystem?Usingthelogicbehind
thisprojectIcanassumethatthedrugwillneverbecompletelyremovedfromherbody.Ifthe
drugsdecayrateis25%everytime,leaving75%behind,thenthenumbercanneverreach0.
Itwillforevergetsmaller,butneverbecompletelyremoved.Somecomplicationswithexcess
amountsinhersystemwouldbethattherateatwhichitdecaysisslowerthanasbeforeI
wouldassume.

9.) Sincethereisaconstantrateofdecay,acontinuousexponentialdecaymodelcanbeusedto
determinehowmuchdrugisinhersystematanytime.
A
(t)=Ao^e^kt

ExponentialDecayModel

WhereA(t)isamountofdruginbloodattimetinhours,
A
istheinitialamountofdrug,and
0
kistherateofdecay(itwillbeanegativenumber)

Youwillhavetofindthe
actual
valueofkthatworksforthismodel.Writedownthe
exponentialdecaymodelfortheamountofdruginDotsbloodasafunctionoftime:

Model:

Nowusethatmodeltofillinthefollowingtable:

TIMESINCE
TAKING
THEDRUG(HR)
0
4
8
12
16
20
24

AMOUNTOF
DRUG
INHERBLOOD
(MG)
1000
750
562.5
421.88
316.41
237.3
177.99

28
32
36
40
44
48
52
56
60
64
68

133.49
100.11
75.09
56.31
42.24
31.68
23.76
17.82
13.36
10.02
7.52

10.) Interprettheparametersofthisexponentialmodelintermsofthecontextoftheproblem.
Theparametersarethatthedrugwilldecaytoacertainpointofnotevenbeingnoticeable,but
itwillalwaysbeinherbloodstream.

11.) Compareyourvalueswiththeestimatedvaluesinthemodel.Howclosewerethey?Why
mighttheybedifferent?Theywereincrediblyclose,andthereasonIthinkthatmakesthem
differentisthatthefirstgraphisroundedwhereasthisoneisprecise.

12.) Useagraphingutilitytographtheoriginaldataalongwithagraphofthemodelonthe
samesetofaxes.


13.) Wereyouexpectingahorizontalasymptote?Whatmightthatmeaninthecontextofthe
problem?YesIwas,becauseofhowIsetupthegraph.Whatthatmeansthough,isthatthis
graphismuchmoreaccuratethanthelattergraph.Thisoneisexact,andtheothergraphis
approximated.

14.) Usingyourmodel,howmuchdrugisinhersystem17hoursaftertakingthedrug?Thereis
294.45milligramsleftinherbodyafter17hours.

15.) Usingyourmodel,howlongwillittakeforexactlyonehalfofthedrugtoremaininher
system?Itwouldtakealittlelessthan10hoursforhalfthedrugtoremaininhersystem.1000
milligrams/2=500milligrams.492.5milligramsappearsat10hours,soroughlybeforethatis
whenhalfthedrugwouldremaininhersysem.

16.) Usingthismodel,howlongwillittakefor0.1mgofthedrugtoremaininhersystem?5
daysand8hours,thesameasabovewillbethetimerequirementofthedrugtobe.1mgin
hersystem.

17.) Doyouthinkthecontinuousdecaymodelismoreaccurateforpredictingtheamountof
druginherblood?Why?Orwhynot?Indeed,Ithinkthecontinuousmodelismoreaccurate
forpredictingtheamountofdruginherblood.Thereasonforthatisthatthecontinuousdrug
modelistheonethatisnotrounded.Itsanexactamountwhereasthestandardmodelis
roundedtothenearestwholenumber.

18.) Whatotherfactorsshouldbeconsideredincomingupwithamorerealisticmodel?Some
thingstobeconsideredwouldbe:didthepatienttakeotherdrugsbesidestheexampleone?
Hasthepersonhadtherequiredamountofsleepandintakentheproperamountofwaterso
thattheirkidneysareworkingatthestandardrate?

19.) Reflectivewriting:Didthisprojectchangethewayyouthinkabouthowmathcanbeapplied
totherealworld?Writeoneparagraphstatingwhatideaschangedandwhy.Ifthisprojectdid
notchangethewayyouthink,writehowthisprojectgavefurtherevidencetosupportyour
existingopinionaboutapplyingmath.Bespecific.Thereasonthisprojectdidntchangemy
viewsonhowmathcanbeappliedtotherealworld,isthatIvedoneprojectslikethisbeforein
highschool.Ialreadyhavebelievedthatmathcanbeeasilyapplicabletotherealworld
almosttoanythinginfact.TheZeroGprojecthelpedmebelievethesamething,inthat
everythingcanbeappliedtomathinonewayoranother.

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