Humoral & cellular

immune responses

Molecules involved for

antigen recognition

B cell receptor & product

T cell receptor (TCR)

antibodies (Abs): immunoglobulin (Ig)

TCR /

Major histocompatibility complex

(MHC)/HLA

Class I
Class II

Immune responses

Natural/innate/nonspecific

Humoral: type I IFN (IFNlysozyme

Cellular: phagocytes, NK cells

Adaptif/acquired/specific

Humoral: Abs: IgM, IgG, IgA, IgE, IgD

Cellular: T cells:

CD4+ Th, CD8+CTL, CD4+CD25+ T reg.

Ab molecule: structure of
immunoglobulin

Immunoglobulin classes

IgM (pentamer)
IgG (monomer):

IgA (monomer and polymer/dimer):

IgG1, IgG2, IgG3, & IgG4 subclasses

IgA1, IgA2 subclasses

IgE (monomer)
IgD (monomer)

Hypersensitivity reactions:

Classification