HS-LS1-4. Use a model to illustrate the role of cellular division (mitosis) and differentiation in producing
and maintaining complex organisms. [Assessment Boundary: Assessment does not include specific gene control
mechanisms or rote memorization of the steps of mitosis.]
HS-LS3-1. Ask questions to clarify relationships about the role of DNA and chromosomes in coding the
instructions for characteristic traits passed from parents to offspring. [Assessment Boundary: Assessment
does not include the phases of meiosis or the biochemical mechanism of specific steps in the process.]
HS-LS3-2. Make and defend a claim based on evidence that inheritable genetic variations may result
from: (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or
(3) mutations caused by environmental factors. [Clarification Statement: Emphasis is on using data to support
arguments for the way variation occurs.] [Assessment Boundary: Assessment does not include the phases of
meiosis or the biochemical mechanism of specific steps in the process.]
In multicellular organisms individual cells grow and then divide via a process called mitosis, thereby allowing the
organism to grow. The organism begins as a single cell (fertilized egg) that divides successively to produce many
cells, with each parent cell passing identical genetic material (two variants of each chromosome pair) to both
daughter cells. Cellular division and differentiation produce and maintain a complex organism, composed of
systems of tissues and organs that work together to meet the needs of the whole organism.
In sexual reproduction, chromosomes can sometimes swap sections during the process of meiosis (cell division),
thereby creating new genetic combinations and thus more genetic variation. Although DNA replication is tightly
regulated and remarkably accurate, errors do occur and result in mutations, which are also a source of genetic
variation. Environmental factors can also cause mutations in genes, and viable mutations are inherited.
Environmental factors also affect expression of traits, and hence affect the probability of occurrences of traits in a
population. Thus the variation and distribution of traits observed depends on both genetic and environmental factors.
Performance Expectations
HS-LS1-4.
Use a model to illustrate the role of cellular division (mitosis) and differentiation in producing and maintaining complex
organisms.
HS-LS3-1.
Ask questions that arise from examining models or a theory to clarify relationships.
HS-LS3-2.
Make and defend a claim based on evidence that inheritable genetic variations may result from: (1) new genetic combinations
through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors.
Lesson 2: (Individual Summative Assessment): After the mitosis lab, students will answer questions on the graphic
organizer and turn it into the teacher. The teacher will hand back graded papers and re-teach material based on how they
students did with the questions.
Lesson 3: (Individual Summative Assessment): Graphic organizer implemented as an Exit Ticket. Students should be able
to individually fill out the Venn Diagram comparing the processes of mitosis and meiosis. This includes: the types of cells
involved, the purpose, the types of cells resulting, and an example involving a specific organism.
Lesson 4: (Individual Summative Assessment): Students will answer questions on an Exit Slip. During this, students will
make and defend claims based on evidence that answer various questions about different genetic and chromosomal mutations,
genetic engineering, and the process of argumentation.
Lesson 1 Cell Growth Cycle
Performance Expectation:
HS-LS1-4 Use a model to illustrate the role
of cellular division and differentiation in
producing and maintaining complex
organisms.
Lesson Objective:
Given an interactive online diagram of
cellular division, students will be able to
explain the steps in cellular division as well
as explain the main roles of each step.
Lesson 2 Mitosis
Performance Expectation:
HS-LS1-4 Use a model to illustrate the role
of cellular division (mitosis) and
differentiation in producing and
maintaining complex organisms.
Lesson Objective:
-Students will take part in a lab on the topic
of mitosis and be able to model mitosis
using pipe cleaners, yarn, and paper.
-Students will also be able to answer
questions on mitosis after completing the
lab.
Lesson 3 Meiosis
Performance Expectation:
HS-LS3-2 Make and defend a claim based
on evidence that inheritable genetic
variations may result from: (1) new genetic
combinations through meiosis, (2) viable
Acceptable Evidence:
-Students will cooperate with group members to correctly identify the purpose
of meiosis in writing.
-Students will complete a Venn Diagram that accurately depicts the similarities
and differences between mitosis and meiosis including, but not limited to: how
the resulting cells differ, which type of cells undergo each process, and the main
functions.
Lesson 4 - Mutations
Performance Expectation:
HS-LS3-1. Ask questions to clarify
relationships about the role of DNA and
chromosomes in coding the instructions for
characteristic traits passed from parents to
offspring
HS-LS3-2. Make and defend a claim
based on evidence that inheritable genetic
variations may result from: (1) new genetic
combinations through meiosis, (2) viable
errors occurring during replication, and/or
(3) mutations caused by environmental
factors.
Lesson Objective:
Students will be able to form arguments and
counter the arguments of others using cited
data from reliable sources.
Useful Websites:
Interactive Cell Cycle: http://media.hhmi.org/biointeractive/click/cellcycle/
Mitosis animation: http://www.johnkyrk.com/mitosis.html
Mitosis game: https://www.centreofthecell.org/learn-play/games/mitosis/
Meiosis animation: http://www.johnkyrk.com/meiosis.html
Meiosis interactive quiz: http://www.biomanbio.com/GamesandLabs/Genegames/snurfle_meiosis_and_genetics.html
Comparison of meiosis and mitosis:
https://highered.mheducation.com/sites/9834092339/student_view0/chapter11/comparison_of_meiosis_and_mitosis.html
Several Scientific Videos: https://www.youtube.com/
GM Humans Ethics: http://www.livescience.com/44087-designer-babies-ethics.html