Acidosis
Group Members
PROBLEM STATEMENT
Lactic Acidosis
CAUSES
It can be divided by 2:
1. Can be prove clinically
eg: left ventricular failure
2. Cannot be prove clinically
Underlying diseases - eg: chronic kidney diseases, diabetes, cancer
Drug - alcohol, aspirin
Inborn errors of metabolism - metabolism errors
Extra Info
This New Drug(DCA) Appears to Cause Cancer Cells to Self-Destruct, however, whether it can reverse
tumor growth without harming you in other ways remains to be seen.
In a test of using DCA in the treatment of lactic acidosis patient, it is observed that dichloroacetate decreased
the lactate concentrations in the treated patients but had no beneficial effects on outcomes. The authors
concluded that dichloroacetate treatment of patients with severe lactic acidosis results in statistically
significant but clinically unimportant changes in arterial blood lactate concentrations and pH and fails to alter
either hemodynamics or survival rates.