osonsa Agen - cp, one Amgen From Wikipedia, the free encyclopedia Amgen (NASDAQ: AMGN (http//www.nasdaq.com/symboVamgn) , Amgen Inc. Type Public ‘Traded as NASDAQ: AMGN (http:!/www.nasdaq.com/symboVamgn) NASDAQ-100 Component S&P 500 Component Industry Biotechnology Founded 1980 Headquarters Thousand Oaks, California, U.S. Key people Kevin W. Sharer (Chairmen) Robert A. Bradway (President and CEO) Products Epogen, Aranesp, Kineret, Enbrel, Neulasta, Neupogen, Nplate, Vectibix, Prolia, Xgeva and Sensipar/Mimpara. Revenue 4 US$ 15.053 billion @o10)l!) Operating A US$ 5.545 billion (20103!) income Net income 4 US$ 4.627 billion (2010)!!! Total assets 4 US$ 43.486 billion (2010)! Total equity 4 US$ 23.294 billion (2010)! Employees 17,400 (December 2010)l!] Website Amgen.com (http:/www-amgen.com) (hitpz/www.hkex.comhk/eng/invest/company/quote_page_e.asp? WidColD=4332&WidCoAbbName=8Month=8clangcode=e) ) is an American-based multinational biopharmaceutical company headquartered in Thousand Oaks, California, Located in the Conejo Valley, Amgen is the world’s largest independent biotechnology firm, Epogen and Neupogen (the companys first products on the market) were the two most successful biopharmaceutical products at the time of their respective rel Amgen is the largest employer in Thousand Oaks and second only to the United States Navy in terms of number of people employed in Ventura County. BusinessWeek ranked Amgen first on the S&P 500 for being one of the most "future-oriented” of those five hundred corporations.! BusinessWeek ostensibly calculated the ratio of research and development spending, combined with capital spending, to total outlays; Amgen had the fourth highest ratio, at 506:1000. enwikipedia orgivikvAmgen 1aoaons2 Amgen Wikipedia, te fre eneylopedia ‘The company employs approximately 17,000 staff members. Its products include Epogen, Aranesp, Enbrel, Kineret, Neulasta, Neupogen, Sensipar/Mimpara, Nplate, Vectibix, Prolia and XGEVA. Amgen has several collaborative arrangements with Pfizer Inc, GlaxoSmithKline, Takeda Pharmaceutical Company, Kyowa Hakko Kirin, Daiichi Sankyo and Array BioPharma." It is a leading member of the U.S. Global Leadership Coalition, a coalition of over 400 companies and NGOs that promotes increased finding for US diplomatic and international development programs./4] In 2010, Amgen began sponsoring the Tour of California, one of only three major Union Cycliste Internationale events in the United States. Contents = 1 History = 2 Acquisition history = 3 Products = 4 Pre Clinical = 5 See ako = 6 References = 7 Extemal links History The word AMGen is a portmanteau of the company's original name, Applied Molecular Genetics, which became the official name of the company in 1983 (three years after incorporation and coincident with its initial public offering). The company's first chief executive officer, from 1980, was George B. Rathmam, followed by Gordon M. Binder in 1988, followed by Kevin W. Sharer in 2000. The company has made at least five major corporate acquisitions. Acquisition history AMGen Corporate Logo, 1983 1994 - Synergen, Inc, 2000 - Kinetix Pharmaceuticals, Inc. 2002 - Immunex Corporation!*! 2004 - Tularik, Inc. 2006 - Abgenix, Inc.|) 2006 - Avidia, Ine. 2007 - Ilypsa, Ine. 2007 - Alantos Pharmaceuticals Holdings, Ine. 2011 - BioVex Group, Inc. ‘Amgen's corporate Gulfstream V 2012 - Micromet, Inc. departs Fox Field, Lancaster, 2012 - Mustafa Nevzat ilag!7] California Products As of August 9, 201 1, Amgen had twelve approved drugs or therapeutic biologicals for seventeen conditions enwikipedia orgivikvAmgen 28osor.t2 Amgen Wikipedia, te fre eneylopedia (conditions lists are highly generalized; see each article for more detail): = Aranesp (darbepoetin alfa) (for anemia) = Enbrel (Etanercept) (for various forms of arthritis) = Epogen (Epoetin) (also known as Procrit; for anemia) = Kepivance (Palifermin) (for oral mucositis) ® Kineret (Anakinra) (for rheumatoid arthritis) = Neupogen (Granulocyte-Colony Stimulating Factor) (for neutropenia) = Neulasta (PEG Gramilocyte-Colony Stinmlating Factor or "Pegtilgrastim’) (for neutropenia) = Vectibix (Panitumumab) (for colon cancer) = Sensipar/Mimpara (Cinacalcet) (for Primary & Secondary hyperparathyroidism, a mineral metabolism complication common in patients with kidney failure) = Nplate (Romiplostim) (for chronic immune thrombocytopenic purpura) = Prolia (denosumab) (for postmenopausal osteoporosis) = XGEVA (denosumab) (for the prevention of skeletal related events (SREs) (pathological fracture, radiation to bone, spinal cord compression or surgery to bone in adults with bone metastases from solid tumors) Pre Clinical In other drug discovery phases (Phases I, Il, III and in preclinical development), the company has twenty-three pharmacologic agents for twenty-eight conditions; nineteen of the candidates are not currently approved for any indication. See also = Kirin Amgen v Hoechst Marion Roussel, a UK patent case decided by the House of Lords References 1, #44 eF~910 Form 10-K, Amgen Inc." (http:/www.sec, gow/Archives/edgar/data/318154/00009501231 1018800/vS71 13e10vk.htm) . U.S. Securities and Exchange Commission, https/iwww.sec. gov/Archives/edgar/data/3 181 54/00009501231 1018800/v57113e10vk.htm, 2. * Coy, Peter (2004-10-11), "The Search for Tomorrow" (http://www. businessweek.com/@ @UPQMF oUQ96PcERW A/magazine/content/04_41/b3903476 htm) BusinessWeek. hitpv/www.businessweck.com/@ @UPQMFoUQ96PcERw Aimagazine/content/04_41/b3903476.htm, access to article requires free registration on site 3. * Dineen, J.K; Leuty, Ron (August 12, 2007). "Amgen Slows its Bay Area Expansion" (http://www. bizjournals.com/sanfrancisco/stories/2007/08/13/story html) . San Francisco Business Times web site. http:/www.bizjournals.com/sanfrancisco/stories/2007/08/13/story1 html, Retrieved August 14, 2007. 4. http:/iwww.usgle.org/about/our-coalition 5. * Amgen Completes Acquisition Of IMMUNEX (bttps/www.amgen.com/media/media_pr_detailjsp? year=2002&releaseID=515163) 6. * Amgen Completes Acquisition of Abgenix; Acquisition Provides Amgen with Full Ownership of Panitumumab and Eliminates a Denosumab Royalty (https//wwwext.amgen.com/media/media_pr_detail sp? year=2006&releaselD=837754) 7. * httpyswww. hurriyet.com. tr/ekonomi/2041567 1 asp enwikipedia orgivikvAmgen sia95.07.12 ‘Amgen - Wikpedia, the free encyclopedia External links = Official website (httpy/Avww.amgen.com) = Company Profile at Pharmaceutical Business Review (http//Avwwpharmaceutical-business- review.com/companies/amgen_inc) = Amgen Inc. Company Profil (http:/finance. google.com/finance?q=amgn&btnG=Search) Profile at Google Finance. = Businessweek.com (http:/nvesting businessweek.comvresearch’stocks/snapshot/snapshot.asp? ticker-AMGN:US) Retrieved from "hitp2/en. wikipedia. org/w/index. php ttleAmgen&oldid=495798743" Categories: Companies in the NASDAQ-100 Index | Amgen | Companies established in 1980 Companies in the NASDAQ Biotechnology Index | Biotechnology companies of the United States Pharmaceutical companies of the United States | Companies based in Ventura County, California Companies based in Thousand Oaks, California = This page was last modified on 3 June 2012 at 17:14. = Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. See Terms of use for detail. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization. enwikipedia orgivikvAmgen aa