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Intestines

Dr.Padmini Wijenayake

Objectives
Revise the structure and the function
Overview of malabsorption
Clinical manifestations and the
pathophysiology of intestinal
infections
Pathophysiology of inflammatory
intestinal diseases
Macroscopical and microscopical
features of intestinal tumors

Pathology
Changes are restricted to the small
intestinal mucosa
Increased rate of loss of epithelial
cells
resulting in progressive decrease in
height of villi (villous atrophy).
Immunologic studies show the
presence of anti-gliadin IgA
antibodies in the mucosa.