Clinical Paper
Oral Surgery
Boworn Klongnoi,
Pariya Kaewpradub,
Kiatanant Boonsiriseth,
Natthamet Wongsirichat
Department of Oral & Maxillofacial Surgery,
Faculty of Dentistry, Mahidol University,
Thailand
Lower impacted third molar (LITM) surgical extraction usually causes complications such as dysaesthesia, severe
infection, bone fracture and dry
socket3. It may also cause facial swelling
and severe pain that may seem important
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# 2011 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
This study showed no postoperative infection and no complications from intramuscular injection of 8 mg dexamethasone.
No significant difference was found for
surgical times between the groups. Dexamethasone significantly reduced postoperative facial swelling after LITM
surgical extraction. The difference was
not significant immediately after LITM
surgical extraction but on postoperative
day 2 a significant difference was found
between the dexamethasone and control
groups in facial swelling; no significant
difference was observed on postoperative
day 7 (Table 2).
This study showed no significant difference between the groups in pain, measured
by visual analogue scale, immediately
after LITM surgical extraction, but dexamethasone was significantly effective in
reducing pain on postoperative days 2 and
Number
Horizontal LITM
Distoangular LITM
Mesioangular LITM
Difficult vertical LITM
10
1
7
2
377
378
Klongnoi et al.
Table 2. Facial swelling (increase in face length after surgery) immediately and on days 2 and 7 after LITM operation.
Time of facial swelling measurements (mm)
Dexamethasone group
Mean
Mean
Immediately postoperation
Day 2 postoperation
Day 7 postoperation
Std. deviation
4.8
8.0
2.8
3.02
5.49
3.5
6.4
16.35
7
p-Value
Std. deviation
5.58
15.37
9
0.48
0.02
0.09
Table 3. VAS of patients pain level immediately and on postoperative days 2 and 7.
Time of pain measurement VAS (mm)
Immediately postoperation
Day 2 postoperation
Day 7 postoperation
Dexamethasone group
Mean
Mean
Std. deviation
2.29
1.24
0.41
2.33
1.50
0.84
2.9
3.38
1.64
p-Value
Std. deviation
3.4
2.74
2.36
0.744
0.001
0.038
Dexamethasone group
Mean
Mean
Std. deviation
6.5
7.4
p-Value
Std. deviation
10.3
11.35
0.03
This study showed no significant difference in surgical times between the dexamethasone and control groups because
life threatening, makes the complete treatment cost higher. The cost of antibiotics in
the authors country is not high. The authors
did not aim to prevent adverse infection
effects from dexamethasone.
Many studies have used dexamethasone
in dentoalveolar surgery to reduce facial
swelling, pain and trismus. Many types,
dosages and times of administration have
been studied for dexamethasone1,6,7,10,9,8,
but no study of 1 h single-dose preoperative intramuscular injection of dexamethasone has been undertaken.
The results for facial swelling showed
that dexamethasone decreased postoperative facial swelling in LITM surgical
extraction, as reported in a previous
review1 by reducing the release of lymphokines, prostaglandins, serotonin and
bradykinin from injured tissue. FILHO
et al.5 reported a decrease in facial swelling on day 2 after operation using 4 and
8 mg dexamethasone, given preoperatively; 8 mg was more effective than
4 mg dexamethasone.
Table 5. Mean maximum mouth opening (interincisal distance) before surgery, immediately, and on postoperative days 2 and 7.
Time of measurement
Dexamethasone group
Mean (mm)
Preoperation
Immediately postoperation
Day 2 postoperation
Day 7 postoperation
Significance level: p < 0.05.
45.5
45.2
45.2
45.4
Mean (mm)
46
45.3
43.5
45.6
p-Value
Std. deviation
4.29
4.3
4.21
4.30
0.38
0.47
0.12
0.47
Funding
None.
Competing interests
None declared.
Ethical approval
7.
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379
Address:
Natthamet Wongsirichat
Department of Oral & Maxillofacial Surgery
Faculty of Dentistry
Mahidol University
6 Yothee Street
Rachathevee
Bangkok 10400
Thailand
Tel: +66 22036511 3; Fax: +66 22036495
E-mail: dtsrp@mahidol.ac.th