Biostatistik
Biostatistik
SKILLAB BIOSTATISTIKA
Nama
NIM
: Ezi Septyandra
: 04011181320032
Tersedia data hasil penelitian profil lipid dan miokard infark sebnyak 250 sampel dengan
catatan sebagai berikut :
Pada variabel Genetik PJK 0 = Genetik PJK Negatif dan kode 1 = Genetik PJK positif.
Pada variabel PJK kode 0 = PJK Negatif dan kode 1 = PJK positif
Kadar gulam darah sewaktu >200 mg% dikategorikan sebagai DM
Klasifikasi propil lipid menunjukkan pada klasipikasi umum propil lipid (terlampir) kecuali
HDL bila < atau sama dengan 40 mg% tidak baik/faktor resiko sedangkan bila >40 mg%
baik/ faktor positif.
1. Buat tabel frekuensi distribusi umur dengan formula sturgess, sajikan dalam bentuk tabel
dan histogram (tiap kelas interval value diwakili oleh midpoin)!
Umur responden
Cumulative
Valid
22-28
Frequency
8
Percent
3.2
Valid Percent
3.2
29-35
24
9.6
9.6
12.8
36-42
37
14.8
14.8
27.6
45.00
51
20.4
20.4
48.0
50-56
40
16.0
16.0
64.0
57-63
44
17.6
17.6
81.6
64-70
34
13.6
13.6
95.2
71-77
2.4
2.4
97.6
78-84
2.4
2.4
100.0
250
100.0
100.0
Total
Percent
3.2
2. Buat variabel baru: IMT (BB/TB2). Buat kategori IMT sesuai ukuran orang asia!
IMT Asia
Cumulative
Valid
underweight
Healthy weight
overwight
heavily
Frequency
76
63
38
Percent
30.4
25.2
15.2
Valid Percent
30.4
25.2
15.2
43
17.2
17.2
88.0
30
12.0
12.0
100.0
250
100.0
100.0
overweight
obese
Total
Percent
30.4
55.6
70.8
df
Shapiro-Wilk
Sig.
Statistic
df
Sig.
IMT Asia
.211
250
.000
.864
250
.000
GDS
.249
250
.000
.556
250
.000
Total kolesterol
.080
250
.000
.942
250
.000
TG
.211
250
.000
.751
250
.000
HDL
.187
250
.000
.904
250
.000
LDL
.082
250
.000
.943
250
.000
P= 0.0005
Non DM
Percent
Valid Percent
Percent
230
92.0
92.0
92.0
DM
20
8.0
8.0
100.0
Total
250
100.0
100.0
10. Genetik PJK dalam bentuk bar diagram atau pie diagram!
Genetik PJK
Cumulative
Frequency
Valid
Percent
Valid Percent
Percent
198
79.2
79.2
79.2
52
20.8
20.8
100.0
250
100.0
100.0
Total
Percent
Valid Percent
Percent
PJK Negatif
180
72.0
72.0
72.0
PJK Positif
70
28.0
28.0
100.0
250
100.0
100.0
Total
12. Korelasi IMT dan kadar gula darah. Apakah korelasi bermakna?
Correlations
Kategori IMT
1.000
.128*
.043
250
250
Correlation Coefficient
.128*
1.000
Sig. (2-tailed)
.043
250
250
GDS
normal
Percent
Valid Percent
Percent
166
66.4
66.4
66.4
51
20.4
20.4
86.8
tinggi
33
13.2
13.2
100.0
Total
250
100.0
100.0
agak
tinggi
Normal
Percent
Valid Percent
Percent
190
76.0
76.0
76.0
Agak tinggi
24
9.6
9.6
85.6
tinggi
34
13.6
13.6
99.2
.8
.8
100.0
250
100.0
100.0
sangat tinggi
Total
Percent
Valid Percent
Percent
normal
71
28.4
28.4
28.4
agak tinggi
73
29.2
29.2
57.6
tinggi
54
21.6
21.6
79.2
sangat tinggi
38
15.2
15.2
94.4
lain-lain
14
5.6
5.6
100.0
250
100.0
100.0
Total
Percent
Valid Percent
Percent
rendah
178
71.2
71.2
71.2
normal
17
6.8
6.8
78.0
tidak terkategori
55
22.0
22.0
100.0
250
100.0
100.0
Total
Normal
PJK Positif
Total
118
48
166
Agak Tinggi
42
51
Tinggi
20
13
33
180
70
250
Total
Chi-Square Tests
Value
df
.086
5.030
.081
Linear-by-Linear Association
.193
.660
N of Valid Cases
250
Pearson Chi-Square
4.906
Likelihood Ratio
a. 0 cells (0.0%) have expected count less than 5. The minimum expected count is 9.24.
P = 0.086, karena P>alfa Ho gagal ditolak
Korelasi kolesterol dan PJK sebesar 8,6% tidak signifikan
Symmetric Measures
Asymp. Std. Errora
Value
Interval by Interval
Pearson's R
Ordinal by Ordinal
Spearman Correlation
Approx. Tb
Approx. Sig.
.028
.067
.439
.661c
-.001
.065
-.016
.987c
N of Valid Cases
250
Normal
PJK Positif
Total
143
47
190
Agak Tinggi
20
24
Tinggi
15
19
34
180
70
250
Sangat Tinggi
Total
Chi-Square Tests
Value
Pearson Chi-Square
Likelihood Ratio
df
16.422a
.001
15.606
.001
Linear-by-Linear Association
7.503
N of Valid Cases
.006
250
a. 2 cells (25.0%) have expected count less than 5. The minimum expected count is .56.
P = 0.001, karena P<alfa Ho ditolak
Korelasi kolesterol dan PJK sebesar 0,1% signifikan
Symmetric Measures
Value
Approx. Tb
Approx. Sig.
Interval by Interval
Pearson's R
.174
.069
2.776
.006c
Ordinal by Ordinal
Spearman Correlation
.151
.068
2.402
.017c
N of Valid Cases
250
PJK Positif
Total
Normal
51
20
71
Agak Tinggi
47
26
73
Tinggi
42
12
54
Sangat Tinggi
32
38
14
180
70
250
Lain-lain
Total
Chi-Square Tests
Value
df
7.339a
.119
7.501
.112
Linear-by-Linear Association
.538
.463
N of Valid Cases
250
Pearson Chi-Square
Likelihood Ratio
a. 1 cells (10.0%) have expected count less than 5. The minimum expected count is 3.92.
Symmetric Measures
Value
Approx. Tb
Approx. Sig.
Interval by Interval
Pearson's R
-.046
.064
-.733
.464c
Ordinal by Ordinal
Spearman Correlation
-.055
.062
-.870
.385c
N of Valid Cases
250
Total
PJK Negatif
kategori HDL
PJK Positif
rendah
131
47
178
normal
11
17
tidak terkategori
38
17
55
180
70
250
Total
Chi-Square Tests
Value
df
.904a
.636
Likelihood Ratio
.882
.643
Linear-by-Linear Association
.565
.452
N of Valid Cases
250
Pearson Chi-Square
a. 1 cells (16.7%) have expected count less than 5. The minimum expected count is 4.76.
Symmetric Measures
Asymp. Std. Errora
Value
Approx. Tb
Approx. Sig.
Interval by Interval
Pearson's R
.048
.064
.751
.453c
Ordinal by Ordinal
Spearman Correlation
.052
.064
.822
.412c
N of Valid Cases
250
18. Hubungan genetik PJK dan kejadian PJK. Gunakan chi square hitung korelasi
Genetik PJK * Penyakit Jantung Koroner Crosstabulation
Count
Penyakit Jantung Koroner
PJK Negatif
Genetik PJK
Total
PJK Positif
Total
171
27
198
43
52
180
70
250
Chi-Square Tests
Value
Pearson Chi-Square
Continuity Correction
df
Likelihood Ratio
sided)
sided)
sided)
.000
94.023
.000
90.831
.000
97.418
b
.000
97.029
.000
250
a. 0 cells (0.0%) have expected count less than 5. The minimum expected count is 14.56.
b. Computed only for a 2x2 table
P = 0.0005, karena P<alfa Ho ditolak
Korelasi kolesterol dan PJK sebesar 0,01% signifikan
.000
Symmetric Measures
Asymp. Std.
Errora
Value
Approx. Tb
Approx. Sig.
Interval by Interval
Pearson's R
.624
.056
12.583
.000c
Ordinal by Ordinal
Spearman Correlation
.624
.056
12.583
.000c
N of Valid Cases
250
19. Hubungan IMT dan kejadian PJK. Gunakan chi square hitung korelasi
Kategori IMT * Penyakit Jantung Koroner Crosstabulation
Count
Penyakit Jantung Koroner
PJK Negatif
Kategori IMT
PJK Positif
Total
Underweight
57
19
76
Healthy Weight
50
13
63
Overweight
20
18
38
Heavily Overweight
37
43
Obese
16
14
30
180
70
250
Total
Chi-Square Tests
Value
Pearson Chi-Square
df
18.499a
.001
18.074
.001
2.123
.145
Likelihood Ratio
Linear-by-Linear Association
N of Valid Cases
250
a. 0 cells (0.0%) have expected count less than 5. The minimum expected count is 8.40.
P = 0.001, karena P<alfa Ho ditolak
Korelasi kolesterol dan PJK sebesar 0,1% signifikan
Symmetric Measures
Asymp. Std.
Value
Errora
Approx. Tb
Approx. Sig.
Interval by Interval
Pearson's R
.092
.065
1.460
.145c
Ordinal by Ordinal
Spearman Correlation
.088
.064
1.394
.165c
N of Valid Cases
250
20. Hubungan umur dan kejadian PJK. Gunakan chi square hitung korelasi
Umur Responden * Penyakit Jantung Koroner Crosstabulation
Count
Penyakit Jantung Koroner
PJK Negatif
Umur Responden
PJK Positif
Total
22 - 28
29 - 35
16
24
36 - 42
24
13
37
43 - 49
39
12
51
50 - 56
28
12
40
57 - 63
37
44
64 - 70
21
13
34
71 - 77
78 - 84
180
70
250
Total
Chi-Square Tests
Value
df
7.318a
.503
7.597
.474
Linear-by-Linear Association
.145
.703
N of Valid Cases
250
Pearson Chi-Square
Likelihood Ratio
a. 5 cells (27.8%) have expected count less than 5. The minimum expected count is 1.68.
P = 0.503, karena P>alfa Ho gagal ditolak
Korelasi kolesterol dan PJK sebesar 50.3% tidak signifikan
Symmetric Measures
Asymp. Std.
Errora
Value
Approx. Tb
Approx. Sig.
Interval by Interval
Pearson's R
-.024
.065
-.380
.704c
Ordinal by Ordinal
Spearman Correlation
-.029
.065
-.452
.652c
N of Valid Cases
250
21. Perbedaan kadar gula darah antar kelompok IMT. Gunakan ANOVA grafik mean
ANOVA
Gula Darah Sewaktu
Sum of Squares
Between Groups
df
Mean Square
8732.748
2183.187
Within Groups
1032254.776
245
4213.285
Total
1040987.524
249
Sig.
.518
.722
22. Perbedaan kadar gula darah antar kelompok umur. Gunakan ANOVA grafik mean
ANOVA
Gula Darah Sewaktu
Sum of Squares
Between Groups
df
Mean Square
39161.066
4895.133
Within Groups
1001826.458
241
4156.956
Total
1040987.524
249
F
1.178
Sig.
.313
23. Perbedaan kadar masing-masing profil lipid berdasarkan JK. Gunakan T student test
independent, buat kesimpulan
24.
Independent Samples Test
Levene's Test
for Equality of
Variances
Sig.
F
Kategori
Equal
Kolesterol
variances
6.585
Sig.
Difference
(2-
Mean
Std. Error
tailed)
Difference
Difference
248
.057
.17296
.09044 -.00517
.35108
1.900 235.606
.059
.17296
.09104 -.00640
.35231
.047
.18850
.09429
.37421
.011 1.912
df
Lower
Upper
assumed
Equal
variances
not
assumed
Kategori
Equal
Trigliserid
variances
assumed
14.524
.000 1.999
248
.00279
Equal
variances
1.972 221.012
not
.050
.18850
.09557
.00015
.37685
248
.650
.06947
.15304 -.23196
.37089
.452 238.256
.652
.06947
.15382 -.23355
.37248
.009
248
.993
.00090
.10566 -.20720
.20899
.008 243.420
.993
.00090
.10580 -.20750
.20930
assumed
Kategori
Equal
LDL
variances
1.283
.259
.454
assumed
Equal
variances
not
assumed
kategori
Equal
HDL
variances
.111
.739
assumed
Equal
variances
not
assumed
Kesimpulan :
Kolesterol, P=0,011 P<alfa Ho ditolak equal variances not assumed. Perbedaan
antara kolesterol dan JK sebesar 0.059 (tidak signifikan)
Trigliserid, P=0,0005 P<alfa Ho ditolak equal variances not assumed. Perbedaan
antara trigliseride dan JK sebesar 0.050 (tidak signifikan)
LDL, P=0,259 P>alfa Ho gagal ditolak equal variances assumed. Perbedaan antara
LDL dan JK sebesar 0.650 (tidak signifikan)
HDL, P=,739 P>alfa Ho gagal ditolak equal variances assumed. Perbedaan antara
HDL dan JK sebesar 0.993(tidak signifikan)
25. Perbedaan kadar masing-masing profil lipid berdasarkan genetik PJK. Gunakan T student
test independent, buat kesimpulan
Independent Samples Test
Levene's Test
for Equality of
Variances
Sig.
F
Sig.
df
(2-
Mean
Std. Error
tailed)
Difference
Difference
Difference
Lower
Upper
Kategori
Equal
Kolesterol
variances
14.077
.000
assumed
248
.148
-.16181
.11158 -.38158
.05796
67.779
.216
-.16181
.12960 -.42045
.09683
248
.027
-.25777
.11575 -.48575
-.02979
68.357
.057
-.25777
.13322 -.52359
.00805
248
.606
.09732
.18821 -.27338
.46802
.474 72.149
.637
.09732
.20522
-.31176
.50640
248
.156
-.18415
.12943 -.43906
.07076
75.485
.178
-.18415
.13551 -.45407
.08577
1.450
Equal
variances
not
1.248
assumed
Kategori
Equal
Trigliserid
variances
15.898
.000
assumed
2.227
Equal
variances
not
1.935
assumed
Kategori
Equal
LDL
variances
1.760
.186
.517
assumed
Equal
variances
not
assumed
kategori
Equal
HDL
variances
3.024
assumed
.083
1.423
Equal
variances
not
1.359
assumed
.249
df
Shapiro-Wilk
Sig.
250
.000
Statistic
.556
df
Sig.
250
.000
a.
df
.155
Shapiro-Wilk
Sig.
250
Statistic
.000
df
.899
Sig.
250
.000
Correlations
Correlations
Gula Darah
Hematokrit
Hematokrit
Pearson Correlation
Sewaktu
1
Sig. (2-tailed)
.041
.521
250
250
Pearson Correlation
.041
Sig. (2-tailed)
.521
250
250
Non DM
DM
Total
PJK Positif
Total
166
64
230
14
20
180
70
250
PJK Positif
Total
43.0-43.5
24
13
37
43.6-44.1
28
13
41
44.8-45.3
26
10
36
46-46.5
33
42
46.6-47.1
33
10
43
47.8-48.3
36
15
51
180
70
250
Total
Chi-Square Tests
Asymp. Sig. (2Value
df
sided)
.755
2.665
.752
Linear-by-Linear Association
.881
.348
N of Valid Cases
250
Pearson Chi-Square
2.645
Likelihood Ratio
P=0,755
= 0,05
P> Ho gagal ditolak hematocrit dan PJK memiliki korelasi yang tidak signifikan
30. Korelasi TD sistolik dan kadar LDL
Correlations
Tekanan Darah
Sistolik
Spearman's rho
Correlation Coefficient
1.000
.098
.121
250
250
Correlation Coefficient
.098
1.000
Sig. (2-tailed)
.121
250
250
Sig. (2-tailed)
Kategori LDL
Kategori LDL
IMT P = 0,001
TD Sistolik P = 0,002
TD Diastolik P = 0,0005
Trigliiserida P = 0,001
32. Buat model prediksi LDL dari seluruh variabel yang relevan
Coefficientsa
Standardized
Unstandardized Coefficients
Model
1
Coefficients
Std. Error
(Constant)
Beta
.610
.120
Kategori Kolesterol
1.222
.073
(Constant)
1.031
.132
Kategori Kolesterol
1.321
.070
Kategori Trigliserid
-.406
.068
t
5.098
.000
16.685
.000
7.806
.000
.786
18.738
.000
-.252
-6.014
.000
.727
33. Buat model regresi logistik kejadian PJK dari seluruh variabel yang relevan
Case Processing Summary
Unweighted Cases
Selected Cases
N
Included in Analysis
Missing Cases
Total
Unselected Cases
Total
Percent
250
100.0
.0
250
100.0
.0
250
100.0
Sig.