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BIOKIMIA

TATA NAMA ENZIM


DAN REAKSI YANG DIKATALISISNYA

Oleh:

Nama : I Gede Dwija Bawa Temaja


Nim : 0808505031

JURUSAN FARMASI
FAKULTAS MATEMATIKA DAN ILMU PENGETAHUAN ALAM
UNIVERSITAS UDAYANA
2010

TATA NAMA ENZIM


Enzim adalah protein yang berfungsi sebagai katalisator untuk reaksi-reaksi kimia didalam
sistem biologi. Katalisator mempercepat reaksi kimia. Walaupun katalisator ikut serta dalam
reaksi, ia kembali ke keadaan semula bila reeaksi telah selesai. Enzim adalah katalisator
protein untuk reaksi-reaksi kimia pasa sistem biologi. sebagian besar reaksi tersebut tidak
dikatalis oleh enzim.

Banyak enzim yang telah dinamakan secara konvensional dengan menambahkan akhiran –ase
kepada nama substratnya. Jadi, urease mengkatalisis hidrolisis urea, dan arginase
mengkatalisis hidrolisis arginin. Tetapi, banyak enzim yang telah diberikan nama dengan tidak
menerangkan substratnya seperti pepsin dan tripsin. Juga pada kenyataannya satu enzim yang
sama dikenal dengan dua atau lebih nama, atau bahwa dua enzim yang berbdeda telah
diberikan nama yang sama. Oleh karena itu dan karena hal-hal lain yang masih kabur, juga
dengan terus meningkatnya jumlah enzim baru yang ditemukan, maka suatu dasar penemuan
nomenklatur dan penggolongan enzim secara sistematis telah dikemukakan dalam persetujuan
internasional oleh “International Enzym Commision” dari IUB-MB (International Union of
Biochemistry Molecular Biology). Sistem nomenklatur ini menggolongkan enzim menjadi 6
golongan utama dan serangkaian sub golongan, berdasarkan jenis reaksi yang dikatalisisnya.
Setiap enzim diberikan satu nama rekomendasi (yang pendek dan praktis untuk penggunaan
sehari-hari), satu nama sistematik (yang mengidentifikasi reaksi yang dikatalisisnya), dan satu
nomor golongan (yang diperlukan apabila diperlukan identifikasi suatu enzim akurat,
misalnya dalam majalah penelitian internasional, abstrak atau indeks).

Gambaran utama sistem IUB (Internasional Union of Biochemistry) untuk klasifikasi enzim
sebagai berikut :
1. Reaksi-reaksi (dan enzim-enzim yang mengkatalisisnya) dibagi dalam 6 kelas utama,
masing-masing kelas dengan 4-13 sub-kelas. 6 kelas utama itu tersusun dibawah ini
dengan beberapa contoh sub-kelas yang penting. Nama yang terdapat dalam kurungan
adalah nama biasa yang lebih dikenal.
2. Nama enzim mempunya 2 bagian. Yang pertama adalah nama substrat atau substrat-
subtrat. Yang kedua, diakhiri dengan “ase”, menunjukan jenis reaksi yang dikatalisis.
Akiran “ase” tidak lagi tercantum langsung pada nama substrat.
3. Keterangan tambahan, bila diperlukan untuk menjelaskan sifat reaksi, dapat didikuti
kata atau kalimat yang diberi tanda kurung. Misalnya, enzim yang mengkatalisis reaksi
L-malat+ NAD+ + piruvat + CO2 + NADH + H = dikenal sebagai enzim malat,
dinamakan 1.1.137 L-malat: NAD oksidoreduktase (dekarboksilase).
4. Masing-masing enzim mempunyai nomer kade sistemik (E.C.). Nomer ini menunjukan
jenis reaksi sebagai kelas (digit pertama), sub-kelas(digit kedua), dan sub-kelas (digit
ketiga). Digit keempat adalah untuk nama enzim tertentu. Jadi, E.C. 2.7.1.1.
menyatakan kelas 2 (transferase), subkelas 7 (pemindahan fosfat), sub-kelas 1 (suatu
alkohol berfungsi sebagai akseptor fosfat). Digit yang terakhir menyatakan enzim,
heksokinase, atau ATP : D-heksosa-6-fosfotransferase, suatu enzim yang mengkatalis
pemindahan fosfat dari ATP kegugus hidroksil pada karbon 6 glikosa.
EC 1. Oxidoreductases
Mengkatalisis transfer atom-atom hidrogen atau oksigen atau elektron dari satu substrat ke
substrat lain. Biasa dikenal juga dengan nama oxidases, dehydrogenases, or reductases.
Karena melibatkan reaksi redoks maka donor/acceptor elektron juga sangat diperlukan untuk
melengkapi reaksi.

EC 1.1 Bekerja Pada Gugus CH-OH Sebagai Donor Elektron

EC 1.1.1 With NAD+ or NADP+ as acceptor

EC 1.1.1.1 alcohol dehydrogenase


EC 1.1.1.2 alcohol dehydrogenase (NADP+)
EC 1.1.1.3 homoserine dehydrogenase
EC 1.1.1.4 (R,R)-butanediol dehydrogenase
EC 1.1.1.5 acetoin dehydrogenase
EC 1.1.1.6 glycerol dehydrogenase
EC 1.1.1.7 propanediol-phosphate dehydrogenase
EC 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+)
EC 1.1.1.9 D-xylulose reductase
EC 1.1.1.10 L-xylulose reductase
EC 1.1.1.11 D-arabinitol 4-dehydrogenase
EC 1.1.1.12 L-arabinitol 4-dehydrogenase
EC 1.1.1.13 L-arabinitol 2-dehydrogenase
EC 1.1.1.14 L-iditol 2-dehydrogenase
EC 1.1.1.15 D-iditol 2-dehydrogenase
EC 1.1.1.16 galactitol 2-dehydrogenase
EC 1.1.1.17 mannitol-1-phosphate 5-dehydrogenase
EC 1.1.1.18 inositol 2-dehydrogenase
EC 1.1.1.19 glucuronate reductase
EC 1.1.1.20 glucuronolactone reductase
EC 1.1.1.21 aldehyde reductase
EC 1.1.1.22 UDP-glucose 6-dehydrogenase
EC 1.1.1.23 histidinol dehydrogenase
EC 1.1.1.24 quinate dehydrogenase
EC 1.1.1.25 shikimate dehydrogenase
EC 1.1.1.26 glyoxylate reductase
EC 1.1.1.27 L-lactate dehydrogenase
EC 1.1.1.28 D-lactate dehydrogenase
EC 1.1.1.29 glycerate dehydrogenase
EC 1.1.1.30 3-hydroxybutyrate dehydrogenase
EC 1.1.1.31 3-hydroxyisobutyrate dehydrogenase
EC 1.1.1.32 mevaldate reductase
EC 1.1.1.33 mevaldate reductase (NADPH)
EC 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
EC 1.1.1.36 acetoacetyl-CoA reductase
EC 1.1.1.37 malate dehydrogenase
EC 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
EC 1.1.1.39 malate dehydrogenase (decarboxylating)
EC 1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
EC 1.1.1.41 isocitrate dehydrogenase (NAD+)
EC 1.1.1.42 isocitrate dehydrogenase (NADP+)
EC 1.1.1.43 phosphogluconate 2-dehydrogenase
EC 1.1.1.44 phosphogluconate dehydrogenase (decarboxylating)
EC 1.1.1.45 L-gulonate 3-dehydrogenase
EC 1.1.1.46 L-arabinose 1-dehydrogenase
EC 1.1.1.47 glucose 1-dehydrogenase
EC 1.1.1.48 galactose 1-dehydrogenase
EC 1.1.1.49 glucose-6-phosphate dehydrogenase
EC 1.1.1.50 3α-hydroxysteroid dehydrogenase (B-specific)
EC 1.1.1.51 3(or 17)β-hydroxysteroid dehydrogenase
EC 1.1.1.52 3α-hydroxycholanate dehydrogenase
EC 1.1.1.53 3α(or 20β)-hydroxysteroid dehydrogenase
EC 1.1.1.54 allyl-alcohol dehydrogenase
EC 1.1.1.55 lactaldehyde reductase (NADPH)
EC 1.1.1.56 ribitol 2-dehydrogenase
EC 1.1.1.57 fructuronate reductase
EC 1.1.1.58 tagaturonate reductase
EC 1.1.1.59 3-hydroxypropionate dehydrogenase
EC 1.1.1.60 2-hydroxy-3-oxopropionate reductase
EC 1.1.1.61 4-hydroxybutyrate dehydrogenase
EC 1.1.1.62 estradiol 17β-dehydrogenase
EC 1.1.1.63 testosterone 17β-dehydrogenase
EC 1.1.1.64 testosterone 17β-dehydrogenase (NADP+)
EC 1.1.1.65 pyridoxine 4-dehydrogenase
EC 1.1.1.66 ω-hydroxydecanoate dehydrogenase
EC 1.1.1.67 mannitol 2-dehydrogenase
EC 1.1.1.68 now EC 1.7.99.5
EC 1.1.1.69 gluconate 5-dehydrogenase
EC 1.1.1.70 deleted, included in EC 1.2.1.3
EC 1.1.1.71 alcohol dehydrogenase [NAD(P)+]
EC 1.1.1.72 glycerol dehydrogenase (NADP+)
EC 1.1.1.73 octanol dehydrogenase
EC 1.1.1.74 deleted
EC 1.1.1.75 (R)-aminopropanal dehydrogenase
EC 1.1.1.76 (S,S)-butanediol dehydrogenase
EC 1.1.1.77 lactaldehyde reductase
EC 1.1.1.78 methylglyoxal reductase (NADH-dependent)
EC 1.1.1.79 glyoxylate reductase (NADP+)
EC 1.1.1.80 isopropanol dehydrogenase (NADP+)
EC 1.1.1.81 hydroxypyruvate reductase
EC 1.1.1.82 malate dehydrogenase (NADP+)
EC 1.1.1.83 D-malate dehydrogenase (decarboxylating)
EC 1.1.1.84 dimethylmalate dehydrogenase
EC 1.1.1.85 3-isopropylmalate dehydrogenase
EC 1.1.1.86 ketol-acid reductoisomerase
EC 1.1.1.87 homoisocitrate dehydrogenase
EC 1.1.1.88 hydroxymethylglutaryl-CoA reductase
EC 1.1.1.89 deleted, included in EC 1.1.1.86
EC 1.1.1.90 aryl-alcohol dehydrogenase
EC 1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
EC 1.1.1.92 oxaloglycolate reductase (decarboxylating)
EC 1.1.1.93 tartrate dehydrogenase
EC 1.1.1.94 glycerol-3-phosphate dehydrogenase [NAD(P)+]
EC 1.1.1.95 phosphoglycerate dehydrogenase
EC 1.1.1.96 diiodophenylpyruvate reductase
EC 1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
EC 1.1.1.98 (R)-2-hydroxy-fatty-acid dehydrogenase
EC 1.1.1.99 (S)-2-hydroxy-fatty-acid dehydrogenase
EC 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
EC 1.1.1.101 acylglycerone-phosphate reductase
EC 1.1.1.102 3-dehydrosphinganine reductase
EC 1.1.1.103 L-threonine 3-dehydrogenase
EC 1.1.1.104 4-oxoproline reductase
EC 1.1.1.105 retinol dehydrogenase
EC 1.1.1.106 pantoate 4-dehydrogenase
EC 1.1.1.107 pyridoxal 4-dehydrogenase
EC 1.1.1.108 carnitine 3-dehydrogenase
EC 1.1.1.109 now EC 1.3.1.28
EC 1.1.1.110 indolelactate dehydrogenase
EC 1.1.1.111 3-(imidazol-5-yl)lactate dehydrogenase
EC 1.1.1.112 indanol dehydrogenase
EC 1.1.1.113 L-xylose 1-dehydrogenase
EC 1.1.1.114 apiose 1-reductase
EC 1.1.1.115 ribose 1-dehydrogenase (NADP+)
EC 1.1.1.116 D-arabinose 1-dehydrogenase
EC 1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
EC 1.1.1.118 glucose 1-dehydrogenase (NAD+)
EC 1.1.1.119 glucose 1-dehydrogenase (NADP+)
EC 1.1.1.120 galactose 1-dehydrogenase (NADP+)
EC 1.1.1.121 aldose 1-dehydrogenase
EC 1.1.1.122 D-threo-aldose 1-dehydrogenase
EC 1.1.1.123 sorbose 5-dehydrogenase (NADP+)
EC 1.1.1.124 fructose 5-dehydrogenase (NADP+)
EC 1.1.1.125 2-deoxy-D-gluconate 3-dehydrogenase
EC 1.1.1.126 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
EC 1.1.1.127 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
EC 1.1.1.128 L-idonate 2-dehydrogenase
EC 1.1.1.129 L-threonate 3-dehydrogenase
EC 1.1.1.130 3-dehydro-L-gulonate 2-dehydrogenase
EC 1.1.1.131 mannuronate reductase
EC 1.1.1.132 GDP-mannose 6-dehydrogenase
EC 1.1.1.133 dTDP-4-dehydrorhamnose reductase
EC 1.1.1.134 dTDP-6-deoxy-L-talose 4-dehydrogenase
EC 1.1.1.135 GDP-6-deoxy-D-talose 4-dehydrogenase
EC 1.1.1.136 UDP-N-acetylglucosamine 6-dehydrogenase
EC 1.1.1.137 ribitol-5-phosphate 2-dehydrogenase
EC 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
EC 1.1.1.139 deleted, included in EC 1.1.1.21
EC 1.1.1.140 sorbitol-6-phosphate 2-dehydrogenase
EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+)
EC 1.1.1.142 D-pinitol dehydrogenase
EC 1.1.1.143 sequoyitol dehydrogenase
EC 1.1.1.144 perillyl-alcohol dehydrogenase
EC 1.1.1.145 3β-hydroxy-Δ5-steroid dehydrogenase
EC 1.1.1.146 11β-hydroxysteroid dehydrogenase
EC 1.1.1.147 16α-hydroxysteroid dehydrogenase
EC 1.1.1.148 estradiol 17α-dehydrogenase
EC 1.1.1.149 20α-hydroxysteroid dehydrogenase
EC 1.1.1.150 21-hydroxysteroid dehydrogenase (NAD+)
EC 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
EC 1.1.1.152 3α-hydroxy-5β-androstane-17-one 3α-dehydrogenase
EC 1.1.1.153 sepiapterin reductase
EC 1.1.1.154 ureidoglycolate dehydrogenase
EC 1.1.1.155 identical to EC 1.1.1.87
EC 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
EC 1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase
EC 1.1.1.158 UDP-N-acetylmuramate dehydrogenase
EC 1.1.1.159 7α-hydroxysteroid dehydrogenase
EC 1.1.1.160 dihydrobunolol dehydrogenase
EC 1.1.1.161 cholestanetetraol 26-dehydrogenase
EC 1.1.1.162 erythrulose reductase
EC 1.1.1.163 cyclopentanol dehydrogenase
EC 1.1.1.164 hexadecanol dehydrogenase
EC 1.1.1.165 2-alkyn-1-ol dehydrogenase
EC 1.1.1.166 hydroxycyclohexanecarboxylate dehydrogenase
EC 1.1.1.167 hydroxymalonate dehydrogenase
EC 1.1.1.168 2-dehydropantolactone reductase (A-specific)
EC 1.1.1.169 2-dehydropantoate 2-reductase
EC 1.1.1.170 3β-hydroxy-4α-methylcholestenecarboxylate 3-dehydrogenase
(decarboxylating)
EC 1.1.1.171 now EC 1.5.1.20
EC 1.1.1.172 2-oxoadipate reductase
EC 1.1.1.173 L-rhamnose 1-dehydrogenase
EC 1.1.1.174 cyclohexane-1,2-diol dehydrogenase
EC 1.1.1.175 D-xylose 1-dehydrogenase
EC 1.1.1.176 12α-hydroxysteroid dehydrogenase
EC 1.1.1.177 glycerol-3-phosphate 1-dehydrogenase (NADP+)
EC 1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
EC 1.1.1.179 D-xylose 1-dehydrogenase (NADP+)
EC 1.1.1.180 deleted, included in EC 1.1.1.131
EC 1.1.1.181 cholest-5-ene-3β,7α-diol 3β-dehydrogenase
EC 1.1.1.182 deleted, included in EC 1.1.1.198, EC 1.1.1.227 and EC 1.1.1.228
EC 1.1.1.183 geraniol dehydrogenase
EC 1.1.1.184 carbonyl reductase (NADPH)
EC 1.1.1.185 L-glycol dehydrogenase
EC 1.1.1.186 dTDP-galactose 6-dehydrogenase
EC 1.1.1.187 GDP-4-dehydro-D-rhamnose reductase
EC 1.1.1.188 prostaglandin-F synthase
EC 1.1.1.189 prostaglandin-E2 9-reductase
EC 1.1.1.190 indole-3-acetaldehyde reductase (NADH)
EC 1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
EC 1.1.1.192 long-chain-alcohol dehydrogenase
EC 1.1.1.193 5-amino-6-(5-phosphoribosylamino)uracil reductase
EC 1.1.1.194 coniferyl-alcohol dehydrogenase
EC 1.1.1.195 cinnamyl-alcohol dehydrogenase
EC 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
EC 1.1.1.198 (+)-borneol dehydrogenase
EC 1.1.1.199 (S)-usnate reductase
EC 1.1.1.200 aldose-6-phosphate reductase (NADPH)
EC 1.1.1.201 7β-hydroxysteroid dehydrogenase (NADP+)
EC 1.1.1.202 1,3-propanediol dehydrogenase
EC 1.1.1.203 uronate dehydrogenase
EC 1.1.1.204 now EC 1.17.1.4
EC 1.1.1.205 IMP dehydrogenase
EC 1.1.1.206 tropinone reductase I
EC 1.1.1.207 (-)-menthol dehydrogenase
EC 1.1.1.208 (+)-neomenthol dehydrogenase
EC 1.1.1.209 3(or 17)α-hydroxysteroid dehydrogenase
EC 1.1.1.210 3β(or 20α)-hydroxysteroid dehydrogenase
EC 1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase
EC 1.1.1.212 3-oxoacyl-[acyl-carrier-protein] reductase (NADH)
EC 1.1.1.213 3α-hydroxysteroid dehydrogenase (A-specific)
EC 1.1.1.214 2-dehydropantolactone reductase (B-specific)
EC 1.1.1.215 gluconate 2-dehydrogenase
EC 1.1.1.216 farnesol dehydrogenase
EC 1.1.1.217 benzyl-2-methyl-hydroxybutyrate dehydrogenase
EC 1.1.1.218 morphine 6-dehydrogenase
EC 1.1.1.219 dihydrokaempferol 4-reductase
EC 1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase
EC 1.1.1.221 vomifoliol 4'-dehydrogenase
EC 1.1.1.222 (R)-4-hydroxyphenyllactate dehydrogenase
EC 1.1.1.223 isopiperitenol dehydrogenase
EC 1.1.1.224 mannose-6-phosphate 6-reductase
EC 1.1.1.225 chlordecone reductase
EC 1.1.1.226 4-hydroxycyclohexanecarboxylate dehydrogenase
EC 1.1.1.227 (-)-borneol dehydrogenase
EC 1.1.1.228 (+)-sabinol dehydrogenase
EC 1.1.1.229 diethyl 2-methyl-3-oxosuccinate reductase
EC 1.1.1.230 3α-hydroxyglycyrrhetinate dehydrogenase
EC 1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
EC 1.1.1.232 15-hydroxyicosatetraenoate dehydrogenase
EC 1.1.1.233 N-acylmannosamine 1-dehydrogenase
EC 1.1.1.234 flavanone 4-reductase
EC 1.1.1.235 8-oxocoformycin reductase
EC 1.1.1.236 tropinone reductase II
EC 1.1.1.237 hydroxyphenylpyruvate reductase
EC 1.1.1.238 12β-hydroxysteroid dehydrogenase
EC 1.1.1.239 3α(17β)-hydroxysteroid dehydrogenase (NAD+)
EC 1.1.1.240 N-acetylhexosamine 1-dehydrogenase
EC 1.1.1.241 6-endo-hydroxycineole dehydrogenase
EC 1.1.1.242 now EC 1.3.1.69
EC 1.1.1.243 carveol dehydrogenase
EC 1.1.1.244 methanol dehydrogenase
EC 1.1.1.245 cyclohexanol dehydrogenase
EC 1.1.1.246 pterocarpin synthase
EC 1.1.1.247 codeinone reductase (NADPH)
EC 1.1.1.248 salutaridine reductase (NADPH)
EC 1.1.1.249 reinstated as EC 2.5.1.46
EC 1.1.1.250 D-arabinitol 2-dehydrogenase
EC 1.1.1.251 galactitol-1-phosphate 5-dehydrogenase
EC 1.1.1.252 tetrahydroxynaphthalene reductase
EC 1.1.1.253 now EC 1.5.1.33
EC 1.1.1.254 (S)-carnitine 3-dehydrogenase
EC 1.1.1.255 mannitol dehydrogenase
EC 1.1.1.256 fluoren-9-ol dehydrogenase
EC 1.1.1.257 4-(hydroxymethyl)benzenesulfonate dehydrogenase
EC 1.1.1.258 6-hydroxyhexanoate dehydrogenase
EC 1.1.1.259 3-hydroxypimeloyl-CoA dehydrogenase
EC 1.1.1.260 sulcatone reductase
EC 1.1.1.261 sn-glycerol-1-phosphate dehydrogenase
EC 1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase
EC 1.1.1.263 1,5-anhydro-D-fructose reductase
EC 1.1.1.264 L-idonate 5-dehydrogenase
EC 1.1.1.265 3-methylbutanal reductase
EC 1.1.1.266 dTDP-4-dehydro-6-deoxyglucose reductase
EC 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase
EC 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase
EC 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase
EC 1.1.1.270 3-keto-steroid reductase
EC 1.1.1.271 GDP-L-fucose synthase
EC 1.1.1.272 (R)-2-hydroxyacid dehydrogenase
EC 1.1.1.273 vellosimine dehydrogenase
EC 1.1.1.274 2,5-didehydrogluconate reductase
EC 1.1.1.275 (+)-trans-carveol dehydrogenase
EC 1.1.1.276 serine 3-dehydrogenase
EC 1.1.1.277 3β-hydroxy-5β-steroid dehydrogenase
EC 1.1.1.278 3β-hydroxy-5α-steroid dehydrogenase
EC 1.1.1.279 (R)-3-hydroxyacid ester dehydrogenase
EC 1.1.1.280 (S)-3-hydroxyacid ester dehydrogenase
EC 1.1.1.281 GDP-4-dehydro-6-deoxy-D-mannose reductase
EC 1.1.1.282 quinate/shikimate dehydrogenase
EC 1.1.1.283 methylglyoxal reductase (NADPH-dependent)
EC 1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase
EC 1.1.1.285 3"-deamino-3"-oxonicotianamine reductase
EC 1.1.1.286 isocitrate—homoisocitrate dehydrogenase
EC 1.1.1.287 D-arabinitol dehydrogenase (NADP+)
EC 1.1.1.288 xanthoxin dehydrogenase
EC 1.1.1.289 sorbose reductase
EC 1.1.1.290 4-phosphoerythronate dehydrogenase
EC 1.1.1.291 2-hydroxymethylglutarate dehydrogenase
EC 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
EC 1.1.1.293 deleted, identical to EC 1.1.1.206
EC 1.1.1.294 chlorophyll(ide) b reductase
EC 1.1.1.295 momilactone-A synthase
EC 1.1.1.296 dihydrocarveol dehydrogenase
EC 1.1.1.297 limonene-1,2-diol dehydrogenase
EC 1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)
EC 1.1.1.299 malate dehydrogenase [NAD(P)+]
EC 1.1.1.300 NADP-retinol dehydrogenase
EC 1.1.1.301 D-arabitol-phosphate dehydrogenase

EC 1.1.2 With a cytochrome as acceptor

EC 1.1.2.1 now EC 1.1.99.5


EC 1.1.2.2 mannitol dehydrogenase (cytochrome)
EC 1.1.2.3 L-lactate dehydrogenase (cytochrome)
EC 1.1.2.4 D-lactate dehydrogenase (cytochrome)
EC 1.1.2.5 D-lactate dehydrogenase (cytochrome c-553)

EC 1.1.3 With oxygen as acceptor


EC 1.1.3.1 deleted, included in EC 1.1.3.15
EC 1.1.3.2 now EC 1.13.12.4
EC 1.1.3.3 malate oxidase
EC 1.1.3.4 glucose oxidase
EC 1.1.3.5 hexose oxidase
EC 1.1.3.6 cholesterol oxidase
EC 1.1.3.7 aryl-alcohol oxidase
EC 1.1.3.8 L-gulonolactone oxidase
EC 1.1.3.9 galactose oxidase
EC 1.1.3.10 pyranose oxidase
EC 1.1.3.11 L-sorbose oxidase
EC 1.1.3.12 pyridoxine 4-oxidase
EC 1.1.3.13 alcohol oxidase
EC 1.1.3.14 catechol oxidase (dimerizing)
EC 1.1.3.15 (S)-2-hydroxy-acid oxidase
EC 1.1.3.16 ecdysone oxidase
EC 1.1.3.17 choline oxidase
EC 1.1.3.18 secondary-alcohol oxidase
EC 1.1.3.19 4-hydroxymandelate oxidase
EC 1.1.3.20 long-chain-alcohol oxidase
EC 1.1.3.21 glycerol-3-phosphate oxidase
EC 1.1.3.22 now EC 1.17.3.2
EC 1.1.3.23 thiamin oxidase
EC 1.1.3.24 now EC 1.3.3.12
EC 1.1.3.25 now included with EC 1.1.99.18
EC 1.1.3.26 now EC 1.21.3.2
EC 1.1.3.27 hydroxyphytanate oxidase
EC 1.1.3.28 nucleoside oxidase
EC 1.1.3.29 N-acylhexosamine oxidase
EC 1.1.3.30 polyvinyl-alcohol oxidase
EC 1.1.3.31 deleted
EC 1.1.3.32 now EC 1.14.21.1
EC 1.1.3.33 now EC 1.14.21.2
EC 1.1.3.34 now EC 1.14.21.3
EC 1.1.3.35 now EC 1.14.21.4
EC 1.1.3.36 now EC 1.14.21.5
EC 1.1.3.37 D-arabinono-1,4-lactone oxidase
EC 1.1.3.38 vanillyl-alcohol oxidase
EC 1.1.3.39 nucleoside oxidase (H2O2-forming)
EC 1.1.3.40 D-mannitol oxidase
EC 1.1.3.41 alditol oxidase
EC 1.1.4 With a disulfide as acceptor
EC 1.1.4.1 vitamin-K-epoxide reductase (warfarin-sensitive)
EC 1.1.4.2 vitamin-K-epoxide reductase (warfarin-insensitive)
EC 1.1.5 With a quinone or similar compound as acceptor
EC 1.1.5.1 deleted
EC 1.1.5.2 quinoprotein glucose dehydrogenase
EC 1.1.5.3 glycerol-3-phosphate dehydrogenase
EC 1.1.5.4 malate dehydrogenase (quinone)
EC 1.1.5.5 alcohol dehydrogenase (quinone)
EC 1.1.5.6 formate dehydrogenase-N
EC 1.1.5.7 cyclic alcohol dehydrogenase (quinone)
EC 1.1.99 With other acceptors
EC 1.1.99.1 choline dehydrogenase
EC 1.1.99.2 2-hydroxyglutarate dehydrogenase
EC 1.1.99.3 gluconate 2-dehydrogenase (acceptor)
EC 1.1.99.4 dehydrogluconate dehydrogenase
EC 1.1.99.5 now EC 1.1.5.3
EC 1.1.99.6 D-2-hydroxy-acid dehydrogenase
EC 1.1.99.7 lactate—malate transhydrogenase
EC 1.1.99.8 alcohol dehydrogenase (acceptor)
EC 1.1.99.9 pyridoxine 5-dehydrogenase
EC 1.1.99.10 glucose dehydrogenase (acceptor)
EC 1.1.99.11 fructose 5-dehydrogenase
EC 1.1.99.12 sorbose dehydrogenase
EC 1.1.99.13 glucoside 3-dehydrogenase
EC 1.1.99.14 glycolate dehydrogenase
EC 1.1.99.15 now EC 1.7.99.5
EC 1.1.99.16 transferred now EC 1.1.5.4
EC 1.1.99.17 now EC 1.1.5.2
EC 1.1.99.18 cellobiose dehydrogenase (acceptor)
EC 1.1.99.19 deleted
EC 1.1.99.20 alkan-1-ol dehydrogenase (acceptor)
EC 1.1.99.21 D-sorbitol dehydrogenase (acceptor)
EC 1.1.99.22 glycerol dehydrogenase (acceptor)
EC 1.1.99.23 polyvinyl-alcohol dehydrogenase (acceptor)
EC 1.1.99.24 hydroxyacid-oxoacid transhydrogenase
EC 1.1.99.25 quinate dehydrogenase (pyrroloquinoline-quinone)
EC 1.1.99.26 3-hydroxycyclohexanone dehydrogenase
EC 1.1.99.27 (R)-pantolactone dehydrogenase (flavin)
EC 1.1.99.28 glucose-fructose oxidoreductase
EC 1.1.99.29 pyranose dehydrogenase (acceptor)
EC 1.1.99.30 2-oxoacid reductase
EC 1.1.99.31 (S)-mandelate dehydrogenase
EC 1.1.99.32 L-sorbose 1-dehydrogenase
EC 1.1.99.33 formate dehydrogenase (acceptor)
EC 1.2 Acting on the aldehyde or oxo group of donors

EC 1.2.1 With NAD or NADP as acceptor


EC 1.2.1.1 deleted, replaced by EC 1.1.1.284 and EC 4.4.1.22
EC 1.2.1.2 formate dehydrogenase
EC 1.2.1.3 aldehyde dehydrogenase (NAD+)
EC 1.2.1.4 aldehyde dehydrogenase (NADP+)
EC 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
EC 1.2.1.6 deleted
EC 1.2.1.7 benzaldehyde dehydrogenase (NADP+)
EC 1.2.1.8 betaine-aldehyde dehydrogenase
EC 1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
EC 1.2.1.10 acetaldehyde dehydrogenase (acetylating)
EC 1.2.1.11 aspartate-semialdehyde dehydrogenase
EC 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
EC 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
(phosphorylating)
EC 1.2.1.14 now EC 1.1.1.205
EC 1.2.1.15 malonate-semialdehyde dehydrogenase
EC 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
EC 1.2.1.17 glyoxylate dehydrogenase (acylating)
EC 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
EC 1.2.1.19 aminobutyraldehyde dehydrogenase
EC 1.2.1.20 glutarate-semialdehyde dehydrogenase
EC 1.2.1.21 glycolaldehyde dehydrogenase
EC 1.2.1.22 lactaldehyde dehydrogenase
EC 1.2.1.23 2-oxoaldehyde dehydrogenase (NAD+)
EC 1.2.1.24 succinate-semialdehyde dehydrogenase
EC 1.2.1.25 2-oxoisovalerate dehydrogenase (acylating)
EC 1.2.1.26 2,5-dioxovalerate dehydrogenase
EC 1.2.1.27 methylmalonate-semialdehyde dehydrogenase (acylating)
EC 1.2.1.28 benzaldehyde dehydrogenase (NAD+)
EC 1.2.1.29 aryl-aldehyde dehydrogenase
EC 1.2.1.30 aryl-aldehyde dehydrogenase (NADP+)
EC 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
EC 1.2.1.32 aminomuconate-semialdehyde dehydrogenase
EC 1.2.1.33 (R)-dehydropantoate dehydrogenase
EC 1.2.1.34 deleted, included in EC 1.1.1.131
EC 1.2.1.35 now EC 1.1.1.203
EC 1.2.1.36 retinal dehydrogenase
EC 1.2.1.37 now EC 1.1.1.204
EC 1.2.1.38 N-acetyl-γ-glutamyl-phosphate reductase
EC 1.2.1.39 phenylacetaldehyde dehydrogenase
EC 1.2.1.40 3α,7α,12α-trihydroxycholestan-26-al 26-oxidoreductase
EC 1.2.1.41 glutamate-5-semialdehyde dehydrogenase
EC 1.2.1.42 hexadecanal dehydrogenase (acylating)
EC 1.2.1.43 formate dehydrogenase (NADP+)
EC 1.2.1.44 cinnamoyl-CoA reductase
EC 1.2.1.45 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase
EC 1.2.1.46 formaldehyde dehydrogenase
EC 1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase
EC 1.2.1.48 long-chain-aldehyde dehydrogenase
EC 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
EC 1.2.1.50 long-chain-fatty-acyl-CoA reductase
EC 1.2.1.51 pyruvate dehydrogenase (NADP+)
EC 1.2.1.52 oxoglutarate dehydrogenase (NADP+)
EC 1.2.1.53 4-hydroxyphenylacetaldehyde dehydrogenase
EC 1.2.1.54 γ-guanidinobutyraldehyde dehydrogenase
EC 1.2.1.55 now EC 1.1.1.279
EC 1.2.1.56 now EC 1.1.1.280
EC 1.2.1.57 butanal dehydrogenase
EC 1.2.1.58 phenylglyoxylate dehydrogenase (acylating)
EC 1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P))
(phosphorylating)
EC 1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
EC 1.2.1.61 4-hydroxymuconic semialdehyde dehydrogenase
EC 1.2.1.62 4-formylbenzenesulfonate dehydrogenase
EC 1.2.1.63 6-oxohexanoate dehydrogenase
EC 1.2.1.64 4-hydroxybenzaldehyde dehydrogenase
EC 1.2.1.65 salicylaldehyde dehydrogenase
EC 1.2.1.66 mycothiol-dependent formaldehyde dehydrogenase
EC 1.2.1.67 vanillin dehydrogenase
EC 1.2.1.68 coniferyl-aldehyde dehydrogenase
EC 1.2.1.69 fluoroacetaldehyde dehydrogenase
EC 1.2.1.70 glutamyl-tRNA reductase
EC 1.2.1.71 succinylglutamate-semialdehyde dehydrogenase
EC 1.2.1.72 erythrose-4-phosphate dehydrogenase
EC 1.2.1.73 sulfoacetaldehyde dehydrogenase
EC 1.2.1.74 abietadienal dehydrogenase
EC 1.2.1.75 malonyl CoA reductase (malonate semialdehyde-forming)
EC 1.2.1.76 succinate-semialdehyde dehydrogenase (acetylating)
EC 1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
EC 1.2.2 With a cytochrome as acceptor
EC 1.2.2.1 formate dehydrogenase (cytochrome)
EC 1.2.2.2 pyruvate dehydrogenase (cytochrome)
EC 1.2.2.3 formate dehydrogenase (cytochrome-c-553)
EC 1.2.2.4 carbon-monoxide dehydrogenase (cytochrome-b-561)
EC 1.2.3 With oxygen as acceptor
EC 1.2.3.1 aldehyde oxidase
EC 1.2.3.2 now EC 1.1.3.22
EC 1.2.3.3 pyruvate oxidase
EC 1.2.3.4 oxalate oxidase
EC 1.2.3.5 glyoxylate oxidase
EC 1.2.3.6 pyruvate oxidase (CoA-acetylating)
EC 1.2.3.7 indole-3-acetaldehyde oxidase
EC 1.2.3.8 pyridoxal oxidase
EC 1.2.3.9 aryl-aldehyde oxidase
EC 1.2.3.10 deleted
EC 1.2.3.11 retinal oxidase
EC 1.2.3.12 now EC 1.14.13.82
EC 1.2.3.13 4-hydroxyphenylpyruvate oxidase
EC 1.2.3.14 abscisic aldehyde oxidase
EC 1.2.4 With a disulfide as acceptor
EC 1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EC 1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
EC 1.2.4.3 deleted, included in EC 1.2.4.4
EC 1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-
transferring)

EC 1.2.7 With an iron-sulfur protein as acceptor


EC 1.2.7.1 pyruvate synthase
EC 1.2.7.2 2-oxobutyrate synthase
EC 1.2.7.3 2-oxoglutarate synthase
EC 1.2.7.4 carbon-monoxide dehydrogenase (ferredoxin)
EC 1.2.7.5 aldehyde ferredoxin oxidoreductase
EC 1.2.7.6 glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)
EC 1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
EC 1.2.7.8 indolepyruvate ferredoxin oxidoreductase
EC 1.2.7.9 deleted, identical to EC 1.2.7.3
EC 1.2.99 With other acceptor
EC 1.2.99.1 now EC 1.17.99.4
EC 1.2.99.2 carbon-monoxide dehydrogenase (acceptor)
EC 1.2.99.3 aldehyde dehydrogenase (pyrroloquinoline-quinone)
EC 1.2.99.4 formaldehyde dismutase
EC 1.2.99.5 formylmethanofuran dehydrogenase
EC 1.2.99.6 carboxylate reductase
EC 1.2.99.7 aldehyde dehydrogenase (FAD-independent)
EC 1.3 Acting on the CH-CH group of donors
EC 1.3.1 With NAD or NADP as acceptor
EC 1.3.1.1 dihydrouracil dehydrogenase (NAD+)
EC 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
EC 1.3.1.3 Δ4-3-oxosteroid 5β-reductase
EC 1.3.1.4 cortisone α-reductase
EC 1.3.1.5 cucurbitacin Δ23-reductase
EC 1.3.1.6 fumarate reductase (NADH)
EC 1.3.1.7 meso-tartrate dehydrogenase
EC 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
EC 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
EC 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH2, B-specific)
EC 1.3.1.11 2-coumarate reductase
EC 1.3.1.12 prephenate dehydrogenase
EC 1.3.1.13 prephenate dehydrogenase (NADP+)
EC 1.3.1.14 orotate reductase (NADH)
EC 1.3.1.15 orotate reductase (NADPH)
EC 1.3.1.16 β-nitroacrylate reductase
EC 1.3.1.17 3-methyleneoxindole reductase
EC 1.3.1.18 kynurenate-7,8-dihydrodiol dehydrogenase
EC 1.3.1.19 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC 1.3.1.21 7-dehydrocholesterol reductase
EC 1.3.1.22 cholestenone 5α-reductase
EC 1.3.1.23 deleted now EC 1.3.1.3
EC 1.3.1.24 biliverdin reductase
EC 1.3.1.25 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
EC 1.3.1.26 dihydrodipicolinate reductase
EC 1.3.1.27 2-hexadecenal reductase
EC 1.3.1.28 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
EC 1.3.1.29 cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
EC 1.3.1.30 progesterone 5α-reductase
EC 1.3.1.31 2-enoate reductase
EC 1.3.1.32 maleylacetate reductase
EC 1.3.1.33 protochlorophyllide reductase
EC 1.3.1.34 2,4-dienoyl-CoA reductase (NADPH)
EC 1.3.1.35 phosphatidylcholine desaturase
EC 1.3.1.36 geissoschizine dehydrogenase
EC 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
EC 1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific)
EC 1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
EC 1.3.1.41 xanthommatin reductase
EC 1.3.1.42 12-oxophytodienoate reductase
EC 1.3.1.43 arogenate dehydrogenase
EC 1.3.1.44 trans-2-enoyl-CoA reductase (NAD+)
EC 1.3.1.45 2'-hydroxyisoflavone reductase
EC 1.3.1.46 biochanin-A reductase
EC 1.3.1.47 α-santonin 1,2-reductase
EC 1.3.1.48 15-oxoprostaglandin 13-oxidase
EC 1.3.1.49 cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
EC 1.3.1.50 now EC 1.1.1.252
EC 1.3.1.51 2'-hydroxydaidzein reductase
EC 1.3.1.52 2-methyl-branched-chain-enoyl-CoA reductase
EC 1.3.1.53 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate
dehydrogenase
EC 1.3.1.54 precorrin-6A reductase
EC 1.3.1.55 now EC 1.3.1.25
EC 1.3.1.56 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
EC 1.3.1.57 phloroglucinol reductase
EC 1.3.1.58 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
EC 1.3.1.59 deleted entry.
EC 1.3.1.60 dibenzothiophene dihydrodiol dehydrogenase
EC 1.3.1.61 deleted, identical to EC 1.3.1.53
EC 1.3.1.62 pimeloyl-CoA dehydrogenase
EC 1.3.1.63 2,4-dichlorobenzoyl-CoA reductase
EC 1.3.1.64 phthalate 4,5-cis-dihydrodiol dehydrogenase
EC 1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline
dehydrogenase
EC 1.3.1.66 cis-dihydroethylcatechol dehydrogenase
EC 1.3.1.67 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate
dehydrogenase
EC 1.3.1.68 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
EC 1.3.1.69 zeatin reductase
EC 1.3.1.70 Δ14-sterol reductase
EC 1.3.1.71 Δ24(24 )-sterol reductase
1

EC 1.3.1.72 Δ24-sterol reductase


EC 1.3.1.73 1,2-dihydrovomilenine reductase
EC 1.3.1.74 2-alkenal reductase
EC 1.3.1.75 divinyl chlorophyllide a 8-vinyl-reductase
EC 1.3.1.76 precorrin-2 dehydrogenase
EC 1.3.1.77 anthocyanidin reductase
EC 1.3.1.78 arogenate dehydrogenase (NADP+)
EC 1.3.1.79 arogenate dehydrogenase [NAD(P)+]
EC 1.3.1.80 red chlorophyll catabolite reductase
EC 1.3.1.81 (+)-pulegone reductase
EC 1.3.1.82 (–)-isopiperitenone reductase
EC 1.3.1.83 geranylgeranyl diphosphate reductase
EC 1.3.1.84 acrylyl-CoA reductase (NADPH)
EC 1.3.2 With a cytochrome as acceptor
EC 1.3.2.1 now EC 1.3.99.2
EC 1.3.2.2 now EC 1.3.99.3
EC 1.3.2.3 L-galactonolactone dehydrogenase
EC 1.3.3 With oxygen as acceptor
EC 1.3.3.1 dihydroorotate oxidase
EC 1.3.3.2 now EC 1.14.21.6
EC 1.3.3.3 coproporphyrinogen oxidase
EC 1.3.3.4 protoporphyrinogen oxidase
EC 1.3.3.5 bilirubin oxidase
EC 1.3.3.6 acyl-CoA oxidase
EC 1.3.3.7 dihydrouracil oxidase
EC 1.3.3.8 tetrahydroberberine oxidase
EC 1.3.3.9 secologanin synthase
EC 1.3.3.10 tryptophan α,β-oxidase
EC 1.3.3.11 pyrroloquinoline-quinone synthase
EC 1.3.3.12 L-galactonolactone oxidase
EC 1.3.5 With a quinone or related compound as acceptor
EC 1.3.5.1 succinate dehydrogenase (ubiquinone)
EC 1.3.5.2 dihydroorotate dehydrogenase
EC 1.3.7 With an iron-sulfur protein as acceptor
EC 1.3.7.1 6-hydroxynicotinate reductase
EC 1.3.7.2 15,16-dihydrobiliverdin:ferredoxin oxidoreductase
EC 1.3.7.3 phycoerythrobilin:ferredoxin oxidoreductase
EC 1.3.7.4 phytochromobilin:ferredoxin oxidoreductase
EC 1.3.7.5 phycocyanobilin:ferredoxin oxidoreductase
EC 1.3.7.6 phycoerythrobilin synthase
EC 1.3.99 With other acceptors
EC 1.3.99.1 succinate dehydrogenase
EC 1.3.99.2 butyryl-CoA dehydrogenase
EC 1.3.99.3 acyl-CoA dehydrogenase
EC 1.3.99.4 3-oxosteroid 1-dehydrogenase
EC 1.3.99.5 3-oxo-5α-steroid 4-dehydrogenase
EC 1.3.99.6 3-oxo-5β-steroid 4-dehydrogenase
EC 1.3.99.7 glutaryl-CoA dehydrogenase
EC 1.3.99.8 2-furoyl-CoA dehydrogenase
EC 1.3.99.9 now EC 1.21.99.1
EC 1.3.99.10 isovaleryl-CoA dehydrogenase
EC 1.3.99.11 now EC 1.3.5.2
EC 1.3.99.12 2-methylacyl-CoA dehydrogenase
EC 1.3.99.13 long-chain-acyl-CoA dehydrogenase
EC 1.3.99.14 cyclohexanone dehydrogenase
EC 1.3.99.15 benzoyl-CoA reductase
EC 1.3.99.16 isoquinoline 1-oxidoreductase
EC 1.3.99.17 quinoline 2-oxidoreductase
EC 1.3.99.18 quinaldate 4-oxidoreductase
EC 1.3.99.19 quinoline-4-carboxylate 2-oxidoreductase
EC 1.3.99.20 4-hydroxybenzoyl-CoA reductase
EC 1.3.99.21 (R)-benzylsuccinyl-CoA dehydrogenase
EC 1.3.99.22 coproporphyrinogen dehydrogenase
EC 1.3.99.23 all-trans-retinol 13,14-reductase
EC 1.3.99.24 2-amino-4-deoxychorismate dehydrogenase
EC 1.3.99.25 carvone reductase
EC 1.4 Acting on the CH-NH2 group of donors
EC 1.4.1 With NAD or NADP as acceptor
EC 1.4.1.1 alanine dehydrogenase
EC 1.4.1.2 glutamate dehydrogenase
EC 1.4.1.3 glutamate dehydrogenase [NAD(P)+]
EC 1.4.1.4 glutamate dehydrogenase (NADP+)
EC 1.4.1.5 L-amino-acid dehydrogenase
EC 1.4.1.6 deleted, included in EC 1.4.4.1
EC 1.4.1.7 serine 2-dehydrogenase
EC 1.4.1.8 valine dehydrogenase (NADP+)
EC 1.4.1.9 leucine dehydrogenase
EC 1.4.1.10 glycine dehydrogenase
EC 1.4.1.11 L-erythro-3,5-diaminohexanoate dehydrogenase
EC 1.4.1.12 2,4-diaminopentanoate dehydrogenase
EC 1.4.1.13 glutamate synthase (NADPH)
EC 1.4.1.14 glutamate synthase (NADH>)
EC 1.4.1.15 lysine dehydrogenase
EC 1.4.1.16 diaminopimelate dehydrogenase
EC 1.4.1.17 N-methylalanine dehydrogenase
EC 1.4.1.18 lysine 6-dehydrogenase
EC 1.4.1.19 tryptophan dehydrogenase
EC 1.4.1.20 phenylalanine dehydrogenase
EC 1.4.1.21 aspartate dehydrogenase
EC 1.4.1.22 deleted
EC 1.4.2 With a cytochrome as acceptor
EC 1.4.2.1 glycine dehydrogenase (cytochrome)
EC 1.4.3 With oxygen as acceptor
EC 1.4.3.1 D-aspartate oxidase
EC 1.4.3.2 L-amino-acid oxidase
EC 1.4.3.3 D-amino-acid oxidase
EC 1.4.3.4 amine oxidase
EC 1.4.3.5 pyridoxal 5'-phosphate synthase
EC 1.4.3.6 now EC 1.4.3.21 and EC 1.4.3.22
EC 1.4.3.7 D-glutamate oxidase
EC 1.4.3.8 ethanolamine oxidase
EC 1.4.3.9 deleted, included in EC 1.4.3.4
EC 1.4.3.10 putrescine oxidase
EC 1.4.3.11 L-glutamate oxidase
EC 1.4.3.12 cyclohexylamine oxidase
EC 1.4.3.13 protein-lysine 6-oxidase
EC 1.4.3.14 L-lysine oxidase
EC 1.4.3.15 D-glutamate(D-aspartate) oxidase
EC 1.4.3.16 L-aspartate oxidase
EC 1.4.3.17 now EC 1.3.3.10
EC 1.4.3.18 deleted, not approved.
EC 1.4.3.19 glycine oxidase
EC 1.4.3.20 L-lysine 6-oxidase
EC 1.4.3.21 primary-amine oxidase
EC 1.4.3.22 diamine oxidase
EC 1.4.3.23 7-chloro-L-tryptophan oxidase
EC 1.4.4 With a disulfide as acceptor
EC 1.4.4.1 now EC 1.21.4.1
EC 1.4.4.2 glycine dehydrogenase (decarboxylating)
EC 1.4.7 With an iron-sulfur protein as acceptor
EC 1.4.7.1 glutamate synthase (ferredoxin)
EC 1.4.99 With other acceptors
EC 1.4.99.1 D-amino-acid dehydrogenase
EC 1.4.99.2 taurine dehydrogenase
EC 1.4.99.3 amine dehydrogenase
EC 1.4.99.4 aralkylamine dehydrogenase
EC 1.4.99.5 glycine dehydrogenase (cyanide-forming)
EC 1.5 Acting on the CH-NH group of donors
EC 1.5.1 With NAD or NADP as acceptor
EC 1.5.1.1 pyrroline-2-carboxylate reductase
EC 1.5.1.2 pyrroline-5-carboxylate reductase
EC 1.5.1.3 dihydrofolate reductase
EC 1.5.1.4 deleted, included in EC 1.5.1.3
EC 1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
EC 1.5.1.6 formyltetrahydrofolate dehydrogenase
EC 1.5.1.7 saccharopine dehydrogenase (NAD+, L-lysine-forming)
EC 1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming)
EC 1.5.1.9 saccharopine dehydrogenase (NAD+, L-glutamate-forming)
EC 1.5.1.10 saccharopine dehydrogenase (NADP+, L-glutamate-forming)
EC 1.5.1.11 D-octopine dehydrogenase
EC 1.5.1.12 1-pyrroline-5-carboxylate dehydrogenase
EC 1.5.1.13 now EC 1.17.1.5
EC 1.5.1.14 deleted, included in EC 1.5.1.21
EC 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
EC 1.5.1.16 D-lysopine dehydrogenase
EC 1.5.1.17 alanopine dehydrogenase
EC 1.5.1.18 ephedrine dehydrogenase
EC 1.5.1.19 D-nopaline dehydrogenase
EC 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
EC 1.5.1.21 Δ1-piperideine-2-carboxylate reductase
EC 1.5.1.22 strombine dehydrogenase
EC 1.5.1.23 tauropine dehydrogenase
EC 1.5.1.24 N5-(carboxyethyl)ornithine synthase
EC 1.5.1.25 thiomorpholine-carboxylate dehydrogenase
EC 1.5.1.26 β-alanopine dehydrogenase
EC 1.5.1.27 1,2-dehydroreticulinium reductase (NADPH)
EC 1.5.1.28 opine dehydrogenase
EC 1.5.1.29 FMN reductase
EC 1.5.1.30 flavin reductase
EC 1.5.1.31 berberine reductase
EC 1.5.1.32 vomilenine reductase
EC 1.5.1.33 pteridine reductase
EC 1.5.1.34 6,7-dihydropteridine reductase
EC 1.5.1.35 deleted, same as EC 1.2.1.19
EC 1.5.3 With oxygen as acceptor
EC 1.5.3.1 sarcosine oxidase
EC 1.5.3.2 N-methyl-L-amino-acid oxidase
EC 1.5.3.3 deleted
EC 1.5.3.4 N6-methyl-lysine oxidase
EC 1.5.3.5 (S)-6-hydroxynicotine oxidase
EC 1.5.3.6 (R)-6-hydroxynicotine oxidase
EC 1.5.3.7 L-pipecolate oxidase
EC 1.5.3.8 deleted, included in EC 1.3.3.8
EC 1.5.3.9 now EC 1.21.3.3
EC 1.5.3.10 dimethylglycine oxidase
EC 1.5.3.11 deleted, now EC 1.5.3.13, EC 1.5.3.14, EC 1.5.3.15, EC 1.5.3.16 and
EC 1.5.3.17
EC 1.5.3.12 dihydrobenzophenanthridine oxidase
EC 1.5.3.13 N1-acetylpolyamine oxidase
EC 1.5.3.14 polyamine oxidase (propane-1,3-diamine-forming)
EC 1.5.3.15 N8-acetylspermidine oxidase (propane-1,3-diamine-forming)
EC 1.5.3.16 spermine oxidase
EC 1.5.3.17 non-specific polyamine oxidase
EC 1.5.4 With a disulfide as acceptor
EC 1.5.4.1 pyrimidodiazepine synthase
EC 1.5.5 With a quinone or similar compound as acceptor
EC 1.5.5.1 electron-transferring-flavoprotein dehydrogenase
EC 1.5.7 With an iron-sulfur protein as acceptor
EC 1.5.7.1 methylenetetrahydrofolate reductase (ferredoxin)
EC 1.5.8 With a flavin as acceptor
EC 1.5.8.1 dimethylamine dehydrogenase
EC 1.5.8.2 trimethylamine dehydrogenase
EC 1.5.99 With other acceptors
EC 1.5.99.1 sarcosine dehydrogenase
EC 1.5.99.2 dimethylglycine dehydrogenase
EC 1.5.99.3 L-pipecolate dehydrogenase
EC 1.5.99.4 nicotine dehydrogenase
EC 1.5.99.5 methylglutamate dehydrogenase
EC 1.5.99.6 spermidine dehydrogenase
EC 1.5.99.7 now EC 1.5.8.2
EC 1.5.99.8 proline dehydrogenase
EC 1.5.99.9 methylenetetrahydromethanopterin dehydrogenase
EC 1.5.99.10 now EC 1.5.8.1
EC 1.5.99.11 5,10-methylenetetrahydromethanopterin reductase
EC 1.5.99.12 cytokinin dehydrogenase
EC 1.6 Acting on NADH or NADPH
EC 1.6.1 With NAD or NADP as acceptor
EC 1.6.1.1 NAD(P)+ transhydrogenase (B-specific)
EC 1.6.1.2 NAD(P)+ transhydrogenase (AB-specific)
EC 1.6.2 With a heme protein as acceptor
EC 1.6.2.1 now EC 1.6.99.3
EC 1.6.2.2 cytochrome-b5 reductase
EC 1.6.2.3 deleted
EC 1.6.2.4 NADPH—hemoprotein reductase
EC 1.6.2.5 NADPH—cytochrome-c2 reductase
EC 1.6.2.6 leghemoglobin reductase
EC 1.6.3 With oxygen as acceptor
EC 1.6.3.1 NAD(P)H oxidase
EC 1.6.4 With a disulfide as acceptor
EC 1.6.4.1 now EC 1.8.1.6
EC 1.6.4.2 now EC 1.8.1.4
EC 1.6.4.3 now EC 1.8.1.7
EC 1.6.4.4 now EC 1.8.1.8
EC 1.6.4.5 now EC 1.8.1.9
EC 1.6.4.6 now EC 1.8.1.10
EC 1.6.4.7 now EC 1.8.1.11
EC 1.6.4.8 now EC 1.8.1.12
EC 1.6.4.9 now EC 1.8.1.13
EC 1.6.4.10 now EC 1.8.1.14
EC 1.6.5 With a quinone or similar compound as acceptor
EC 1.6.5.1 deleted
EC 1.6.5.2 NAD(P)H dehydrogenase (quinone)
EC 1.6.5.3 NADH dehydrogenase (ubiquinone)
EC 1.6.5.4 monodehydroascorbate reductase (NADH)
EC 1.6.5.5 NADPH:quinone reductase
EC 1.6.5.6 p-benzoquinone reductase (NADPH)
EC 1.6.5.7 2-hydroxy-1,4-benzoquinone reductase
EC 1.6.6 With a nitrogenous group as acceptor
EC 1.6.6.1 now EC 1.7.1.1
EC 1.6.6.2 now EC 1.7.1.2
EC 1.6.6.3 now EC 1.7.1.3
EC 1.6.6.4 now EC 1.7.1.4
EC 1.6.6.5 now EC 1.7.99.3
EC 1.6.6.6 now EC 1.7.1.5
EC 1.6.6.7 now EC 1.7.1.6
EC 1.6.6.8 now EC 1.7.1.7
EC 1.6.6.9 trimethylamine-N-oxide reductase
EC 1.6.6.10 now EC 1.7.1.9
EC 1.6.6.11 now EC 1.7.1.10
EC 1.6.6.12 now EC 1.7.1.11
EC 1.6.6.13 now EC 1.7.1.12
EC 1.6.7 With a iron-sulfur protein as acceptor
EC 1.6.7.1 now EC 1.18.1.2
EC 1.6.7.2 now EC 1.18.1.1
EC 1.6.7.3 now EC 1.18.1.2

EC 1.6.8 With a flavin as acceptor


EC 1.6.8.1 now EC 1.5.1.29
EC 1.6.8.2 now EC 1.5.1.30
EC 1.6.99 With other acceptors
EC 1.6.99.1 NADPH dehydrogenase
EC 1.6.99.2 now EC 1.6.5.2
EC 1.6.99.3 NADH dehydrogenase
EC 1.6.99.4 now EC 1.18.1.2
EC 1.6.99.5 NADH dehydrogenase (quinone)
EC 1.6.99.6 NADPH dehydrogenase (quinone)
EC 1.6.99.7 now EC 1.5.1.34
EC 1.6.99.8 now EC 1.16.1.3
EC 1.6.99.9 now EC 1.16.1.4
EC 1.6.99.10 deleted, included in EC 1.5.1.34
EC 1.6.99.11 now EC 1.16.1.5
EC 1.6.99.12 now EC 1.16.1.6
EC 1.6.99.13 now EC 1.16.1.7
EC 1.7 Acting on other nitrogenous compounds as donors
EC 1.7.1 With NAD+ or NADP+ as acceptor
EC 1.7.1.1 nitrate reductase (NADH+)
EC 1.7.1.2 nitrate reductase [NAD(P)H+]
EC 1.7.1.3 nitrate reductase (NADPH+)
EC 1.7.1.4 nitrite reductase [NAD(P)H+]
EC 1.7.1.5 hyponitrite reductase
EC 1.7.1.6 azobenzene reductase
EC 1.7.1.7 GMP reductase
EC 1.7.1.8 deleted entry
EC 1.7.1.9 nitroquinoline-N-oxide reductase
EC 1.7.1.10 hydroxylamine reductase (NADH+)
EC 1.7.1.11 4-(dimethylamino)phenylazoxybenzene reductase
EC 1.7.1.12 N-hydroxy-2-acetamidofluorene reductase
EC 1.7.1.13 preQ1 reductase
EC 1.7.2 With a cytochrome as acceptor
EC 1.7.2.1 nitrite reductase (NO-forming)
EC 1.7.2.2 nitrite reductase (cytochrome; ammonia-forming)
EC 1.7.2.3 trimethylamine-N-oxide reductase (cytochrome c)

EC 1.7.3 With oxygen as acceptor


EC 1.7.3.1 nitroalkane oxidase
EC 1.7.3.2 acetylindoxyl oxidase
EC 1.7.3.3 urate oxidase
EC 1.7.3.4 hydroxylamine oxidase
EC 1.7.3.5 3-aci-nitropropanoate oxidase
EC 1.7.7 With an iron-sulfur protein as acceptor
EC 1.7.7.1 ferredoxin-nitrite reductase
EC 1.7.7.2 ferredoxin-nitrate reductase
EC 1.7.99 With other acceptors
EC 1.7.99.1 hydroxylamine reductase
EC 1.7.99.2 deleted
EC 1.7.99.3 included with EC 1.7.2.1
EC 1.7.99.4 nitrate reductase
EC 1.7.99.5 deleted, now included with EC 1.5.1.20
EC 1.7.99.6 nitrous-oxide reductase
EC 1.7.99.7 nitric-oxide reductase
EC 1.7.99.8 hydroxylamine oxidoreductase
EC 1.8 Acting on a sulfur group of donors
EC 1.8.1 With NAD or NADP as acceptor
EC 1.8.1.1 deleted
EC 1.8.1.2 sulfite reductase (NADPH)
EC 1.8.1.3 hypotaurine dehydrogenase
EC 1.8.1.4 dihydrolipoyl dehydrogenase
EC 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
EC 1.8.1.6 cystine reductase
EC 1.8.1.7 glutathione-disulfide reductase
EC 1.8.1.8 protein-disulfide reductase
EC 1.8.1.9 thioredoxin-disulfide reductase
EC 1.8.1.10 CoA-glutathione reductase
EC 1.8.1.11 asparagusate reductase
EC 1.8.1.12 trypanothione-disulfide reductase
EC 1.8.1.13 bis-γ-glutamylcystine reductase
EC 1.8.1.14 CoA-disulfide reductase
EC 1.8.1.15 mycothione reductase
EC 1.8.1.16 glutathione amide reductase

EC 1.8.2 With a cytochrome as acceptor


EC 1.8.2.1 sulfite dehydrogenase
EC 1.8.2.2 thiosulfate dehydrogenase
EC 1.8.3 With oxygen as acceptor
EC 1.8.3.1 sulfite oxidase
EC 1.8.3.2 thiol oxidase
EC 1.8.3.3 glutathione oxidase
EC 1.8.3.4 methanethiol oxidase
EC 1.8.3.5 prenylcysteine oxidase
EC 1.8.4 With a disulfide as acceptor
EC 1.8.4.1 glutathione-homocystine transhydrogenase
EC 1.8.4.2 protein-disulfide reductase (glutathione)
EC 1.8.4.3 glutathione-CoA-glutathione transhydrogenase
EC 1.8.4.4 glutathione-cystine transhydrogenase
EC 1.8.4.5 now EC 1.8.4.13 and EC 1.8.4.14
EC 1.8.4.6 now EC 1.8.4.11
EC 1.8.4.7 enzyme-thiol transhydrogenase (glutathione-disulfide)
EC 1.8.4.8 phosphoadenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.9 adenylyl-sulfate reductase (glutathione)
EC 1.8.4.10 adenylyl-sulfate reductase (thioredoxin)
EC 1.8.4.11 peptide-methionine (S)-S-oxide reductase
EC 1.8.4.12 peptide-methionine (R)-S-oxide reductase
EC 1.8.4.13 L-methionine (S)-S-oxide reductase
EC 1.8.4.14 L-methionine (R)-S-oxide reductase
EC 1.8.5 With a quinone or similar compound as acceptor
EC 1.8.5.1 glutathione dehydrogenase (ascorbate)
EC 1.8.5.2 thiosulfate dehydrogenase (quinone)
EC 1.8.6 With an nitrogenous group as acceptor
EC 1.8.6.1 deleted, included in EC 2.5.1.18
EC 1.8.7 With an iron-sulfur protein as acceptor
EC 1.8.7.1 sulfite reductase (ferredoxin)

EC 1.8.98 With other, known, acceptors


EC 1.8.98.1 CoB—CoM heterodisulfide reductase
EC 1.8.98.2 sulfiredoxin
EC 1.8.99 With other acceptors
EC 1.8.99.1 sulfite reductase
EC 1.8.99.2 adenylyl-sulfate reductase
EC 1.8.99.3 hydrogensulfite reductase
EC 1.8.99.4 now EC 1.8.4.8
EC 1.9 Acting on a heme group of donors
EC 1.9.3 With oxygen as acceptor
EC 1.9.3.1 cytochrome-c oxidase
EC 1.9.3.2 included with EC 1.7.2.1
EC 1.9.6 With a nitrogenous group as acceptor
EC 1.9.99 With other acceptors
EC 1.9.99.1 iron-cytochrome-c reductase
EC 1.10 Acting on diphenols and related substances as donors
EC 1.10.1 With NAD or NADP as acceptor
EC 1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase
EC 1.10.2 With a cytochrome as acceptor
EC 1.10.2.1 L-ascorbate—cytochrome-b5 reductase
EC 1.10.2.2 ubiquinol—cytochrome-c reductase
EC 1.10.3 With oxygen as acceptor
EC 1.10.3.1 catechol oxidase
EC 1.10.3.2 laccase
EC 1.10.3.3 L-ascorbate oxidase
EC 1.10.3.4 o-aminophenol oxidase
EC 1.10.3.5 3-hydroxyanthranilate oxidase
EC 1.10.3.6 rifamycin-B oxidase
EC 1.10.3.7 now EC 1.21.3.4
EC 1.10.3.8 now EC 1.21.3.5
EC 1.10.99 With other acceptors
EC 1.10.99.1 plastoquinol—plastocyanin reductase
EC 1.10.99.2 ribosyldihydronicotinamide dehydrogenase (quinone)
EC 1.10.99.3 violaxanthin de-epoxidase
EC 1.11 Acting on a peroxide as acceptor
EC 1.11.1 Peroxidases
EC 1.11.1.1 NADH peroxidase
EC 1.11.1.2 NADPH peroxidase
EC 1.11.1.3 fatty-acid peroxidase
EC 1.11.1.4 now EC 1.13.11.11
EC 1.11.1.5 cytochrome-c peroxidase
EC 1.11.1.6 catalase
EC 1.11.1.7 peroxidase
EC 1.11.1.8 iodide peroxidase
EC 1.11.1.9 glutathione peroxidase
EC 1.11.1.10 chloride peroxidase
EC 1.11.1.11 L-ascorbate peroxidase
EC 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase
EC 1.11.1.13 manganese peroxidase
EC 1.11.1.14 lignin peroxidase
EC 1.11.1.15 peroxiredoxin
EC 1.11.1.16 versatile peroxidase
EC 1.11.1.17 glutathione amide-dependent peroxidase
EC 1.12 Acting on hydrogen as donor
EC 1.12.1 With NAD or NADP as acceptor
EC 1.12.1.1 now EC 1.18.99.1
EC 1.12.1.2 hydrogen dehydrogenase
EC 1.12.1.3 hydrogen dehydrogenase (NADP+)
EC 1.12.2 With a cytochrome as acceptor
EC 1.12.2.1 cytochrome-c3 hydrogenase
EC 1.12.5 With a quinone or similar compound as acceptor
EC 1.12.5.1 hydrogen:quinone oxidoreductase

EC 1.12.7 With an iron-sulfur protein as acceptor


EC 1.12.7.1 now EC 1.18.99.1
EC 1.12.7.2 ferredoxin hydrogenase
EC 1.12.98 With other known acceptors
EC 1.12.98.1 coenzyme F420 hydrogenase
EC 1.12.98.2 5,10-methenyltetrahydromethanopterin hydrogenase
EC 1.12.98.3 Methanosarcina-phenazine hydrogenase
EC 1.12.99 With other acceptors
EC 1.12.99.1 now EC 1.12.98.1
EC 1.12.99.2 deleted
EC 1.12.99.3 now EC 1.12.5.1
EC 1.12.99.4 now EC 1.12.98.2
EC 1.12.99.5 deleted, identical to EC 1.13.11.47
EC 1.12.99.6 hydrogenase (acceptor)
EC 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
EC 1.13.1 (transferred to EC 1.13.11)
EC 1.13.1.1 now EC 1.13.11.1
EC 1.13.1.2 now EC 1.13.11.2
EC 1.13.1.3 now EC 1.13.11.3
EC 1.13.1.4 now EC 1.13.11.4
EC 1.13.1.5 now EC 1.13.11.5
EC 1.13.1.6 now EC 1.13.11.6
EC 1.13.1.7 now EC 1.13.11.7
EC 1.13.1.8 now EC 1.13.11.8
EC 1.13.1.9 now EC 1.13.11.9
EC 1.13.1.10 now EC 1.13.11.10
EC 1.13.1.11 now EC 1.13.99.1
EC 1.13.1.12 now EC 1.13.11.11
EC 1.13.1.13 now EC 1.13.11.12
EC 1.13.11 With incorporation of two atoms of oxygen
EC 1.13.11.1 catechol 1,2-dioxygenase
EC 1.13.11.2 catechol 2,3-dioxygenase
EC 1.13.11.3 protocatechuate 3,4-dioxygenase
EC 1.13.11.4 gentisate 1,2-dioxygenase
EC 1.13.11.5 homogentisate 1,2-dioxygenase
EC 1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase
EC 1.13.11.7 deleted
EC 1.13.11.8 protocatechuate 4,5-dioxygenase
EC 1.13.11.9 2,5-dihydroxypyridine 5,6-dioxygenase
EC 1.13.11.10 7,8-dihydroxykynurenate 8,8a-dioxygenase
EC 1.13.11.11 tryptophan 2,3-dioxygenase
EC 1.13.11.12 lipoxygenase
EC 1.13.11.13 ascorbate 2,3-dioxygenase
EC 1.13.11.14 2,3-dihydroxybenzoate 3,4-dioxygenase
EC 1.13.11.15 3,4-dihydroxyphenylacetate 2,3-dioxygenase
EC 1.13.11.16 3-carboxyethylcatechol 2,3-dioxygenase
EC 1.13.11.17 indole 2,3-dioxygenase
EC 1.13.11.18 sulfur dioxygenase
EC 1.13.11.19 cysteamine dioxygenase
EC 1.13.11.20 cysteine dioxygenase
EC 1.13.11.21 now EC 1.14.99.36
EC 1.13.11.22 caffeate 3,4-dioxygenase
EC 1.13.11.23 2,3-dihydroxyindole 2,3-dioxygenase
EC 1.13.11.24 quercetin 2,3-dioxygenase
EC 1.13.11.25 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-
dioxygenase
EC 1.13.11.26 peptide-tryptophan 2,3-dioxygenase
EC 1.13.11.27 4-hydroxyphenylpyruvate dioxygenase
EC 1.13.11.28 2,3-dihydroxybenzoate 2,3-dioxygenase
EC 1.13.11.29 stizolobate synthase
EC 1.13.11.30 stizolobinate synthase
EC 1.13.11.31 arachidonate 12-lipoxygenase
EC 1.13.11.32 transferred now EC 1.13.12.16
EC 1.13.11.33 arachidonate 15-lipoxygenase
EC 1.13.11.34 arachidonate 5-lipoxygenase
EC 1.13.11.35 pyrogallol 1,2-oxygenase
EC 1.13.11.36 chloridazon-catechol dioxygenase
EC 1.13.11.37 hydroxyquinol 1,2-dioxygenase
EC 1.13.11.38 1-hydroxy-2-naphthoate 1,2-dioxygenase
EC 1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase
EC 1.13.11.40 arachidonate 8-lipoxygenase
EC 1.13.11.41 2,4'-dihydroxyacetophenone dioxygenase
EC 1.13.11.42 deleted
EC 1.13.11.43 lignostilbene αβ-dioxygenase
EC 1.13.11.44 linoleate diol synthase
EC 1.13.11.45 linoleate 11-lipoxygenase
EC 1.13.11.46 4-hydroxymandelate synthase
EC 1.13.11.47 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
EC 1.13.11.48 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase
EC 1.13.11.49 chlorite O2-lyase
EC 1.13.11.50 acetylacetone-cleaving enzyme
EC 1.13.11.51 9-cis-epoxycarotenoid dioxygenase
EC 1.13.11.52 indoleamine 2,3-dioxygenase
EC 1.13.11.53 acireductone dioxygenase (Ni2+-requiring)
EC 1.13.11.54 acireductone dioxygenase [iron(II)-requiring]
EC 1.13.11.55 sulfur oxygenase/reductase
EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal
mixed function oxidases)
EC 1.13.12.1 arginine 2-monooxygenase
EC 1.13.12.2 lysine 2-monooxygenase
EC 1.13.12.3 tryptophan 2-monooxygenase
EC 1.13.12.4 lactate 2-monooxygenase
EC 1.13.12.5 Renilla-luciferin 2-monooxygenase
EC 1.13.12.6 Cypridina-luciferin 2-monooxygenase
EC 1.13.12.7 Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)
EC 1.13.12.8 Watasenia-luciferin 2-monooxygenase
EC 1.13.12.9 phenylalanine 2-monooxygenase
EC 1.13.12.10 deleted, reaction covered by EC 1.14.13.59
EC 1.13.12.11 now EC 1.14.13.8
EC 1.13.12.12 apo-β-carotenoid-14',13'-dioxygenase
EC 1.13.12.13 Oplophorus-luciferin 2-monooxygenase
EC 1.13.12.14 chlorophyllide a oxygenase
EC 1.13.12.15 3,4-dihydroxyphenylalanine oxidative deaminase
EC 1.13.12.16 nitronate monooxygenase
EC 1.13.12.17 dichloroarcyriaflavin A synthase
EC 1.13.99 Miscellaneous
EC 1.13.99.1 inositol oxygenase
EC 1.13.99.2 now EC 1.14.12.10
EC 1.13.99.3 tryptophan 2'-dioxygenase
EC 1.13.99.4 now EC 1.14.12.9
EC 1.13.99.5 now EC 1.13.11.47
EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
EC 1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)
EC 1.14.1.1 now EC 1.14.14.1
EC 1.14.1.2 now EC 1.14.13.9
EC 1.14.1.3 deleted, covered by EC 1.14.99.7, EC 5.4.99.7
EC 1.14.1.4 now EC 1.14.99.2
EC 1.14.1.5 now EC 1.14.13.5
EC 1.14.1.6 now EC 1.14.15.4
EC 1.14.1.7 now EC 1.14.99.9
EC 1.14.1.8 now EC 1.14.99.10
EC 1.14.1.9 deleted
EC 1.14.1.10 now EC 1.14.99.11
EC 1.14.1.11 deleted
EC 1.14.2 With ascorbate as one donor (deleted sub-subclass)
EC 1.14.2.1 now EC 1.14.17.1
EC 1.14.2.2 now EC 1.13.11.27
EC 1.14.3 With reduced pteridine as one donor (deleted sub-subclass)
EC 1.14.3.1 now EC 1.14.16.1
EC 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen
into both donors
EC 1.14.11.1 γ-butyrobetaine dioxygenase
EC 1.14.11.2 procollagen-proline dioxygenase
EC 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase
EC 1.14.11.4 procollagen-lysine 5-dioxygenase
EC 1.14.11.5 deleted, included in EC 1.14.11.6
EC 1.14.11.6 thymine dioxygenase
EC 1.14.11.7 procollagen-proline 3-dioxygenase
EC 1.14.11.8 trimethyllysine dioxygenase
EC 1.14.11.9 flavanone 3-dioxygenase
EC 1.14.11.10 pyrimidine-deoxynucleoside 1'-dioxygenase
EC 1.14.11.11 hyoscyamine (6S)-dioxygenase
EC 1.14.11.12 gibberellin-44 dioxygenase
EC 1.14.11.13 gibberellin 2β-dioxygenase
EC 1.14.11.14 6β-hydroxyhyoscyamine epoxidase
EC 1.14.11.15 gibberellin 3β-dioxygenase
EC 1.14.11.16 peptide-aspartate β-dioxygenase
EC 1.14.11.17 taurine dioxygenase
EC 1.14.11.18 phytanoyl-CoA dioxygenase
EC 1.14.11.19 leucocyanidin oxygenase
EC 1.14.11.20 deacetoxyvindoline 4-hydroxylase
EC 1.14.11.21 clavaminate synthase
EC 1.14.11.22 flavone synthase
EC 1.14.11.23 flavonol synthase
EC 1.14.11.24 2'-deoxymugineic-acid 2'-dioxygenase
EC 1.14.11.25 mugineic-acid 3-dioxygenase
EC 1.14.11.26 deacetoxycephalosporin-C hydroxylase
EC 1.14.11.27 [histone-H3]-lysine-36 demethylase
EC 1.14.11.28 proline 3-hydroxylase
EC 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen
into one donor
EC 1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
EC 1.14.12.2 now EC 1.14.13.35
EC 1.14.12.3 benzene 1,2-dioxygenase
EC 1.14.12.4 3-hydroxy-2-methylpyridinecarboxylate dioxygenase
EC 1.14.12.5 5-pyridoxate dioxygenase
EC 1.14.12.6 now EC 1.14.13.66
EC 1.14.12.7 phthalate 4,5-dioxygenase
EC 1.14.12.8 4-sulfobenzoate 3,4-dioxygenase
EC 1.14.12.9 4-chlorophenylacetate 3,4-dioxygenase
EC 1.14.12.10 benzoate 1,2-dioxygenase
EC 1.14.12.11 toluene dioxygenase
EC 1.14.12.12 naphthalene 1,2-dioxygenase
EC 1.14.12.13 2-chlorobenzoate 1,2-dioxygenase
EC 1.14.12.14 2-aminobenzenesulfonate 2,3-dioxygenase
EC 1.14.12.15 terephthalate 1,2-dioxygenase
EC 1.14.12.16 2-hydroxyquinoline 5,6-dioxygenase
EC 1.14.12.17 nitric oxide dioxygenase
EC 1.14.12.18 biphenyl 2,3-dioxygenase
EC 1.14.12.19 3-phenylpropionate dioxygenase
EC 1.14.12.20 pheophorbide a oxygenase
EC 1.14.12.21 benzoyl-CoA 2,3-dioxygenase
EC 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen
EC 1.14.13.1 salicylate 1-monooxygenase
EC 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
EC 1.14.13.3 4-hydroxyphenylacetate 3-monooxygenase
EC 1.14.13.4 melilotate 3-monooxygenase
EC 1.14.13.5 imidazoleacetate 4-monooxygenase
EC 1.14.13.6 orcinol 2-monooxygenase
EC 1.14.13.7 phenol 2-monooxygenase
EC 1.14.13.8 flavin-containing monooxygenase
EC 1.14.13.9 kynurenine 3-monooxygenase
EC 1.14.13.10 2,6-dihydroxypyridine 3-monooxygenase
EC 1.14.13.11 trans-cinnamate 4-monooxygenase
EC 1.14.13.12 benzoate 4-monooxygenase
EC 1.14.13.13 calcidiol 1-monooxygenase
EC 1.14.13.14 trans-cinnamate 2-monooxygenase
EC 1.14.13.15 cholestanetriol 26-monooxygenase
EC 1.14.13.16 cyclopentanone monooxygenase
EC 1.14.13.17 cholesterol 7α-monooxygenase
EC 1.14.13.18 4-hydroxyphenylacetate 1-monooxygenase
EC 1.14.13.19 taxifolin 8-monooxygenase
EC 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
EC 1.14.13.21 flavonoid 3'-monooxygenase
EC 1.14.13.22 cyclohexanone monooxygenase
EC 1.14.13.23 3-hydroxybenzoate 4-monooxygenase
EC 1.14.13.24 3-hydroxybenzoate 6-monooxygenase
EC 1.14.13.25 methane monooxygenase
EC 1.14.13.26 phosphatidylcholine 12-monooxygenase
EC 1.14.13.27 4-aminobenzoate 1-monooxygenase
EC 1.14.13.28 3,9-dihydroxypterocarpan 6a-monooxygenase
EC 1.14.13.29 4-nitrophenol 2-monooxygenase
EC 1.14.13.30 leukotriene-B4 20-monooxygenase
EC 1.14.13.31 2-nitrophenol 2-monooxygenase
EC 1.14.13.32 albendazole monooxygenase
EC 1.14.13.33 4-hydroxybenzoate 3-monooxygenase [NAD(P)H]
EC 1.14.13.34 leukotriene-E4 20-monooxygenase
EC 1.14.13.35 anthranilate 3-monooxygenase (deaminating)
EC 1.14.13.36 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
EC 1.14.13.37 methyltetrahydroprotoberberine 14-monooxygenase
EC 1.14.13.38 anhydrotetracycline monooxygenase
EC 1.14.13.39 nitric-oxide synthase
EC 1.14.13.40 anthraniloyl-CoA monooxygenase
EC 1.14.13.41 tyrosine N-monooxygenase
EC 1.14.13.42 hydroxyphenylacetonitrile 2-monooxygenase
EC 1.14.13.43 questin monooxygenase
EC 1.14.13.44 2-hydroxybiphenyl 3-monooxygenase
EC 1.14.13.45 now EC 1.14.18.2
EC 1.14.13.46 (-)-menthol monooxygenase
EC 1.14.13.47 (S)-limonene 3-monooxygenase
EC 1.14.13.48 (S)-limonene 6-monooxygenase
EC 1.14.13.49 (S)-limonene 7-monooxygenase
EC 1.14.13.50 pentachlorophenol monooxygenase
EC 1.14.13.51 6-oxocineole dehydrogenase
EC 1.14.13.52 isoflavone 3'-hydroxylase
EC 1.14.13.53 4'-methoxyisoflavone 2'-hydroxylase
EC 1.14.13.54 ketosteroid monooxygenase
EC 1.14.13.55 protopine 6-monooxygenase
EC 1.14.13.56 dihydrosanguinarine 10-monooxygenase
EC 1.14.13.57 dihydrochelirubine 12-monooxygenase
EC 1.14.13.58 benzoyl-CoA 3-monooxygenase
EC 1.14.13.59 L-lysine 6-monooxygenase (NADPH)
EC 1.14.13.60 27-hydroxycholesterol 7α-monooxygenase
EC 1.14.13.61 2-hydroxyquinoline 8-monooxygenase
EC 1.14.13.62 4-hydroxyquinoline 3-monooxygenase
EC 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase
EC 1.14.13.64 4-hydroxybenzoate 1-hydroxylase
EC 1.14.13.65 deleted
EC 1.14.13.66 2-hydroxycyclohexanone 2-monooxygenase
EC 1.14.13.67 quinine 3-monooxygenase
EC 1.14.13.68 4-hydroxyphenylacetaldehyde oxime monooxygenase
EC 1.14.13.69 alkene monooxygenase
EC 1.14.13.70 sterol 14-demethylase
EC 1.14.13.71 N-methylcoclaurine 3'-monooxygenase
EC 1.14.13.72 methylsterol monooxygenase
EC 1.14.13.73 tabersonine 16-hydroxylase
EC 1.14.13.74 7-deoxyloganin 7-hydroxylase
EC 1.14.13.75 vinorine hydroxylase
EC 1.14.13.76 taxane 10β-hydroxylase
EC 1.14.13.77 taxane 13α-hydroxylase
EC 1.14.13.78 ent-kaurene oxidase
EC 1.14.13.79 ent-kaurenoic acid oxidase
EC 1.14.13.80 (R)-limonene 6-monooxygenase
EC 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
EC 1.14.13.82 vanillate monooxygenase
EC 1.14.13.83 precorrin-3B synthase
EC 1.14.13.84 4-hydroxyacetophenone monooxygenase
EC 1.14.13.85 glyceollin synthase
EC 1.14.13.86 2-hydroxyisoflavanone synthase
EC 1.14.13.87 licodione synthase
EC 1.14.13.88 flavonoid 3',5'-hydroxylase
EC 1.14.13.89 isoflavone 2'-hydroxylase
EC 1.14.13.90 zeaxanthin epoxidase
EC 1.14.13.91 deoxysarpagine hydroxylase
EC 1.14.13.92 phenylacetone monooxygenase
EC 1.14.13.93 (+)-abscisic acid 8'-hydroxylase
EC 1.14.13.94 lithocholate 6β-hydroxylase
EC 1.14.13.95 7α-hydroxycholest-4-en-3-one 12α-hydroxylase
EC 1.14.13.96 5β-cholestane-3α,7α-diol 12α-hydroxylase
EC 1.14.13.97 taurochenodeoxycholate 6α-hydroxylase
EC 1.14.13.98 cholesterol 24-hydroxylase
EC 1.14.13.99 24-hydroxycholesterol 7α-hydroxylase
EC 1.14.13.100 25-hydroxycholesterol 7α-hydroxylase
EC 1.14.13.101 senecionine N-oxygenase
EC 1.14.13.102 psoralen synthase
EC 1.14.13.103 8-dimethylallylnaringenin 2'-hydroxylase
EC 1.14.13.104 (+)-menthofuran synthase
EC 1.14.13.105 monocyclic monoterpene ketone monooxygenase
EC 1.14.13.106 epi-isozizaene 5-monooxygenase
EC 1.14.13.107 limonene 1,2-monooxygenase
EC 1.14.13.108 abietadiene hydroxylase
EC 1.14.13.109 abietadienol hydroxylase
EC 1.14.13.110 geranylgeraniol 18-hydroxylase
EC 1.14.13.111 methanesulfonate monooxygenase
EC 1.14.13.112 3-epi-6-deoxocathasterone 23-monooxygenase
EC 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom
of oxygen
EC 1.14.14.1 unspecific monooxygenase
EC 1.14.14.2 deleted, included in EC 1.14.14.1
EC 1.14.14.3 alkanal monooxygenase (FMN-linked)
EC 1.14.14.4 deleted, identical to EC 1.14.15.7
EC 1.14.14.5 alkanesulfonate monooxygenase
EC 1.14.14.6 transferred now EC 1.14.13.111
EC 1.14.14.7 tryptophan 7-halogenase
EC 1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of
oxygen
EC 1.14.15.1 camphor 5-monooxygenase
EC 1.14.15.2 camphor 1,2-monooxygenase
EC 1.14.15.3 alkane 1-monooxygenase
EC 1.14.15.4 steroid 11β-monooxygenase
EC 1.14.15.5 corticosterone 18-monooxygenase
EC 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
EC 1.14.15.7 choline monooxygenase
EC 1.14.15.8 steroid 15β-monooxygenase
EC 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen
EC 1.14.16.1 phenylalanine 4-monooxygenase
EC 1.14.16.2 tyrosine 3-monooxygenase
EC 1.14.16.3 anthranilate 3-monooxygenase
EC 1.14.16.4 tryptophan 5-monooxygenase
EC 1.14.16.5 glyceryl-ether monooxygenase
EC 1.14.16.6 mandelate 4-monooxygenase
EC 1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen
EC 1.14.17.1 dopamine β-monooxygenase
EC 1.14.17.2 deleted, included in EC 1.14.18.1
EC 1.14.17.3 peptidylglycine monooxygenase
EC 1.14.17.4 aminocyclopropanecarboxylate oxidase
EC 1.14.18 With another compound as one donor, and incorporation of one atom of oxygen
EC 1.14.18.1 monophenol monooxygenase
EC 1.14.18.2 CMP-N-acetylneuraminate monooxygenase
EC 1.14.19 With oxidation of a pair of donors resulting in the reduction of molecular oxygen
to two molecules of water
EC 1.14.19.1 stearoyl-CoA 9-desaturase
EC 1.14.19.2 acyl-[acyl-carrier-protein] desaturase
EC 1.14.19.3 linoleoyl-CoA desaturase
EC 1.14.19.4 Δ8-fatty-acid desaturase
EC 1.14.19.5 Δ11-fatty-acid desaturase
EC 1.14.19.6 Δ12-fatty-acid desaturase
EC 1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
EC 1.14.20.1 deacetoxycephalosporin-C synthase
EC 1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated
EC 1.14.21.1 (S)-stylopine synthase
EC 1.14.21.2 (S)-cheilanthifoline synthase
EC 1.14.21.3 berbamunine synthase
EC 1.14.21.4 salutaridine synthase
EC 1.14.21.5 (S)-canadine synthase
EC 1.14.21.6 lathosterol oxidase
EC 1.14.21.7 biflaviolin synthase
EC 1.14.99 Miscellaneous
EC 1.14.99.1 prostaglandin-endoperoxide synthase
EC 1.14.99.2 kynurenine 7,8-hydroxylase
EC 1.14.99.3 heme oxygenase
EC 1.14.99.4 progesterone monooxygenase
EC 1.14.99.5 now EC 1.14.19.1
EC 1.14.99.6 now EC 1.14.19.2
EC 1.14.99.7 squalene monooxygenase
EC 1.14.99.8 deleted, included in EC 1.14.14.1
EC 1.14.99.9 steroid 17α-monooxygenase
EC 1.14.99.10 steroid 21-monooxygenase
EC 1.14.99.11 estradiol 6β-monooxygenase
EC 1.14.99.12 4-androstene-3,17-dione monooxygenase
EC 1.14.99.13 now EC 1.14.13.23
EC 1.14.99.14 progesterone 11α-monooxygenase
EC 1.14.99.15 4-methoxybenzoate monooxygenase (O-demethylating)
EC 1.14.99.16 now EC 1.14.13.72
EC 1.14.99.17 now EC 1.14.16.5
EC 1.14.99.18 deleted
EC 1.14.99.19 plasmanylethanolamine desaturase
EC 1.14.99.20 phylloquinone monooxygenase (2,3-epoxidizing)
EC 1.14.99.21 Latia-luciferin monooxygenase (demethylating)
EC 1.14.99.22 ecdysone 20-monooxygenase
EC 1.14.99.23 3-hydroxybenzoate 2-monooxygenase
EC 1.14.99.24 steroid 9α-monooxygenase
EC 1.14.99.25 now EC 1.14.19.3
EC 1.14.99.26 2-hydroxypyridine 5-monooxygenase
EC 1.14.99.27 juglone 3-monooxygenase
EC 1.14.99.28 linalool 8-monooxygenase
EC 1.14.99.29 deoxyhypusine monooxygenase
EC 1.14.99.30 carotene 7,8-desaturase
EC 1.14.99.31 myristoyl-CoA 11-(E) desaturase
EC 1.14.99.32 myristoyl-CoA 11-(Z) desaturase
EC 1.14.99.33 Δ12-fatty acid dehydrogenase
EC 1.14.99.34 monoprenyl isoflavone epoxidase
EC 1.14.99.35 thiophene-2-carbonyl-CoA monooxygenase
EC 1.14.99.36 β-carotene 15,15'-monooxygenase
EC 1.14.99.37 taxadiene 5α-hydroxylase
EC 1.14.99.38 cholesterol 25-hydroxylase
EC 1.14.99.39 ammonia monooxygenase
EC 1.15 Acting on superoxide radicals as acceptor
EC 1.15.1 (only sub-subclass identified to date)
EC 1.15.1.1 superoxide dismutase
EC 1.15.1.2 superoxide reductase
EC 1.16 Oxidising metal ions
EC 1.16.1 With NAD or NADP as acceptor
EC 1.16.1.1 mercury(II) reductase
EC 1.16.1.2 diferric-transferrin reductase
EC 1.16.1.3 aquacobalamin reductase
EC 1.16.1.4 cob(II)alamin reductase
EC 1.16.1.5 aquacobalamin reductase (NADPH)
EC 1.16.1.6 cyanocobalamin reductase (cyanide-eliminating)
EC 1.16.1.7 ferric-chelate reductase
EC 1.16.1.8 [methionine synthase] reductase
EC 1.16.3 With oxygen as acceptor
EC 1.16.3.1 ferroxidase

EC 1.16.8 With flavin as acceptor


EC 1.16.8.1 cob(II)yrinic acid a,c-diamide reductase
EC 1.17 Acting on CH or CH2 groups
EC 1.17.1 With NAD or NADP as acceptor
EC 1.17.1.1 CDP-4-dehydro-6-deoxyglucose reductase
EC 1.17.1.2 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
EC 1.17.1.3 leucoanthocyanidin reductase
EC 1.17.1.4 xanthine dehydrogenase
EC 1.17.1.5 nicotinate dehydrogenase
EC 1.17.1.6 now EC 1.17.99.5
EC 1.17.3 With oxygen as acceptor
EC 1.17.3.1 pteridine oxidase
EC 1.17.3.2 xanthine oxidase
EC 1.17.3.3 6-hydroxynicotinate dehydrogenase
EC 1.17.4 With a disulfide as acceptor
EC 1.17.4.1 ribonucleoside-diphosphate reductase
EC 1.17.4.2 ribonucleoside-triphosphate reductase
EC 1.17.4.3 transferred now EC 1.17.7.1
EC 1.17.5 With a quinone or similar compound as acceptor
EC 1.17.5.1 phenylacetyl-CoA dehydrogenase
EC 1.17.7 With an iron-sulfur protein as acceptor
EC 1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase
EC 1.17.99 With other acceptors
EC 1.17.99.1 4-cresol dehydrogenase (hydroxylating)
EC 1.17.99.2 ethylbenzene hydroxylase
EC 1.17.99.3 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase
EC 1.17.99.4 uracil/thymine dehydrogenase
EC 1.17.99.5 bile-acid 7α-dehydroxylase
EC 1.18 Acting on iron-sulfur proteins as donors
EC 1.18.1 With NAD+ or NADP+ as acceptor
EC 1.18.1.1 rubredoxin—NAD+ reductase
EC 1.18.1.2 ferredoxin—NADP+ reductase
EC 1.18.1.3 ferredoxin—NAD+ reductase
EC 1.18.1.4 rubredoxin—NAD(P)+ reductase
EC 1.18.2 With dinitrogen as acceptor (transferred to EC 1.18.6)
EC 1.18.2.1 now EC 1.18.6.1
EC 1.18.3 With H+ as acceptor
EC 1.18.3.1 now EC 1.18.99.1
EC 1.18.6 With dinitrogen as acceptor
EC 1.18.6.1 nitrogenase
EC 1.18.96 With other, known, acceptors
EC 1.18.96.1 now EC 1.15.1.2
EC 1.18.99 With H+ as acceptor
EC 1.18.99.1 now EC 1.12.7.2
EC 1.19 Acting on reduced flavodoxin as donor
EC 1.19.6 With dinitrogen as acceptor
EC 1.19.6.1 nitrogenase (flavodoxin)
EC 1.20 Acting on phosphorus or arsenic in donors
EC 1.20.1 Acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor
EC 1.20.1.1 phosphonate dehydrogenase
EC 1.20.4 Acting on phosphorus or arsenic in donors, with disulfide as acceptor
EC 1.20.4.1 arsenate reductase (glutaredoxin)
EC 1.20.4.2 methylarsonate reductase
EC 1.20.98 Acting on phosphorus or arsenic in donors, with other, known acceptors
EC 1.20.98.1 arsenate reductase (azurin)
EC 1.20.99 Acting on phosphorus or arsenic in donors, with other acceptors
EC 1.20.99.1 arsenate reductase (donor)
EC 1.21 Acting on X-H and Y-H to form an X-Y bond
EC 1.21.3 With oxygen as acceptor
EC 1.21.3.1 isopenicillin-N synthase
EC 1.21.3.2 columbamine oxidase
EC 1.21.3.3 reticuline oxidase
EC 1.21.3.4 sulochrin oxidase [(+)-bisdechlorogeodin-forming]
EC 1.21.3.5 sulochrin oxidase [(-)-bisdechlorogeodin-forming]
EC 1.21.3.6 aureusidin synthase
EC 1.21.4 With a disulfide as acceptor
EC 1.21.4.1 D-proline reductase (dithiol)
EC 1.21.4.2 glycine reductase
EC 1.21.4.3 sarcosine reductase
EC 1.21.4.4 betaine reductase
EC 1.21.99 With other acceptors
EC 1.21.99.1 β-cyclopiazonate dehydrogenase
EC 1.97 Other oxidoreductases
EC 1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses
EC 1.97.1.1 chlorate reductase
EC 1.97.1.2 pyrogallol hydroxyltransferase
EC 1.97.1.3 sulfur reductase
EC 1.97.1.4 [formate-C-acetyltransferase]-activating enzyme
EC 1.97.1.5 now EC 1.20.4.1
EC 1.97.1.6 now EC 1.20.99.1
EC 1.97.1.7 now EC 1.20.4.2
EC 1.97.1.8 tetrachloroethene reductive dehalogenase
EC 1.97.1.9 selenate reductase
EC 1.97.1.10 thyroxine 5'-deiodinase
EC 1.97.1.11 thyroxine 5-deiodinase
EC 2 Transferases
Enzim-enzim yang mengkatalisis pemindahan suatu gugus, G (lain dari hidrogen), antara
sepasang substrat S dan S’.
S-G + S’ = S’-G + S
EC 2.1 Transferring one-carbon groups
EC 2.1.1 Methyltransferases
EC 2.1.1.1 nicotinamide N-methyltransferase
EC 2.1.1.2 guanidinoacetate N-methyltransferase
EC 2.1.1.3 thetin—homocysteine S-methyltransferase
EC 2.1.1.4 acetylserotonin O-methyltransferase
EC 2.1.1.5 betaine—homocysteine S-methyltransferase
EC 2.1.1.6 catechol O-methyltransferase
EC 2.1.1.7 nicotinate N-methyltransferase
EC 2.1.1.8 histamine N-methyltransferase
EC 2.1.1.9 thiol S-methyltransferase
EC 2.1.1.10 homocysteine S-methyltransferase
EC 2.1.1.11 magnesium protoporphyrin IX methyltransferase
EC 2.1.1.12 methionine S-methyltransferase
EC 2.1.1.13 methionine synthase
EC 2.1.1.14 5-methyltetrahydropteroyltriglutamate—homocysteine S-
methyltransferase
EC 2.1.1.15 fatty-acid O-methyltransferase
EC 2.1.1.16 methylene-fatty-acyl-phospholipid synthase
EC 2.1.1.17 phosphatidylethanolamine N-methyltransferase
EC 2.1.1.18 polysaccharide O-methyltransferase
EC 2.1.1.19 trimethylsulfonium—tetrahydrofolate N-methyltransferase
EC 2.1.1.20 glycine N-methyltransferase
EC 2.1.1.21 methylamine—glutamate N-methyltransferase
EC 2.1.1.22 carnosine N-methyltransferase
EC 2.1.1.23 now covered by EC 2.1.1.124, EC 2.1.1.125 and EC 2.1.1.126
EC 2.1.1.24 now covered by EC 2.1.1.77, EC 2.1.1.80 and EC 2.1.1.100
EC 2.1.1.25 phenol O-methyltransferase
EC 2.1.1.26 iodophenol O-methyltransferase
EC 2.1.1.27 tyramine N-methyltransferase
EC 2.1.1.28 phenylethanolamine N-methyltransferase
EC 2.1.1.29 tRNA (cytosine-5-)-methyltransferase
EC 2.1.1.30 deleted
EC 2.1.1.31 tRNA (guanine-N1-)-methyltransferase
EC 2.1.1.32 tRNA (guanine-N2-)-methyltransferase
EC 2.1.1.33 tRNA (guanine-N7-)-methyltransferase
EC 2.1.1.34 tRNA guanosine-2'-O-methyltransferase
EC 2.1.1.35 tRNA (uracil-5-)-methyltransferase
EC 2.1.1.36 tRNA (adenine-N1-)-methyltransferase
EC 2.1.1.37 DNA (cytosine-5-)-methyltransferase
EC 2.1.1.38 O-demethylpuromycin O-methyltransferase
EC 2.1.1.39 inositol 3-methyltransferase
EC 2.1.1.40 inositol 1-methyltransferase
EC 2.1.1.41 sterol 24-C-methyltransferase
EC 2.1.1.42 luteolin O-methyltransferase
EC 2.1.1.43 histone-lysine N-methyltransferase
EC 2.1.1.44 dimethylhistidine N-methyltransferase
EC 2.1.1.45 thymidylate synthase
EC 2.1.1.46 isoflavone 4'-O-methyltransferase
EC 2.1.1.47 indolepyruvate C-methyltransferase
EC 2.1.1.48 rRNA (adenine-N6-)-methyltransferase
EC 2.1.1.49 amine N-methyltransferase
EC 2.1.1.50 loganate O-methyltransferase
EC 2.1.1.51 rRNA (guanine-N1-)-methyltransferase
EC 2.1.1.52 rRNA (guanine-N2-)-methyltransferase
EC 2.1.1.53 putrescine N-methyltransferase
EC 2.1.1.54 deoxycytidylate C-methyltransferase
EC 2.1.1.55 tRNA (adenine-N6-)-methyltransferase
EC 2.1.1.56 mRNA (guanine-N7-)-methyltransferase
EC 2.1.1.57 mRNA (nucleoside-2'-O-)-methyltransferase
EC 2.1.1.58 deleted, included in EC 2.1.1.57
EC 2.1.1.59 [cytochrome c]-lysine N-methyltransferase
EC 2.1.1.60 calmodulin-lysine N-methyltransferase
EC 2.1.1.61 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase
EC 2.1.1.62 mRNA (2'-O-methyladenosine-N6-)-methyltransferase
EC 2.1.1.63 methylated-DNA—[protein]-cysteine S-methyltransferase
EC 2.1.1.64 3-demethylubiquinone-9 3-O-methyltransferase
EC 2.1.1.65 licodione 2'-O-methyltransferase
EC 2.1.1.66 rRNA (adenosine-2'-O-)-methyltransferase
EC 2.1.1.67 thiopurine S-methyltransferase
EC 2.1.1.68 caffeate O-methyltransferase
EC 2.1.1.69 5-hydroxyfuranocoumarin 5-O-methyltransferase
EC 2.1.1.70 8-hydroxyfuranocoumarin 8-O-methyltransferase
EC 2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase
EC 2.1.1.72 site-specific DNA-methyltransferase (adenine-specific)
EC 2.1.1.73 deleted
EC 2.1.1.74 methylenetetrahydrofolate—tRNA-(uracil-5-)-methyltransferase
(FADH2-oxidizing)
EC 2.1.1.75 apigenin 4'-O-methyltransferase
EC 2.1.1.76 quercetin 3-O-methyltransferase
EC 2.1.1.77 protein-L-isoaspartate(D-aspartate) O-methyltransferase
EC 2.1.1.78 isoorientin 3'-O-methyltransferase
EC 2.1.1.79 cyclopropane-fatty-acyl-phospholipid synthase
EC 2.1.1.80 protein-glutamate O-methyltransferase
EC 2.1.1.81 deleted, included in EC 2.1.1.49
EC 2.1.1.82 3-methylquercetin 7-O-methyltransferase
EC 2.1.1.83 3,7-dimethylquercetin 4'-O-methyltransferase
EC 2.1.1.84 methylquercetagetin 6-O-methyltransferase
EC 2.1.1.85 protein-histidine N-methyltransferase
EC 2.1.1.86 tetrahydromethanopterin S-methyltransferase
EC 2.1.1.87 pyridine N-methyltransferase
EC 2.1.1.88 8-hydroxyquercetin 8-O-methyltransferase
EC 2.1.1.89 tetrahydrocolumbamine 2-O-methyltransferase
EC 2.1.1.90 methanol—5-hydroxybenzimidazolylcobamide Co-methyltransferase
EC 2.1.1.91 isobutyraldoxime O-methyltransferase
EC 2.1.1.92 deleted, now EC 2.1.1.69
EC 2.1.1.93 deleted, identical to EC 2.1.1.70
EC 2.1.1.94 tabersonine 16-O-methyltransferase
EC 2.1.1.95 tocopherol O-methyltransferase
EC 2.1.1.96 thioether S-methyltransferase
EC 2.1.1.97 3-hydroxyanthranilate 4-C-methyltransferase
EC 2.1.1.98 diphthine synthase
EC 2.1.1.99 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase
EC 2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase
EC 2.1.1.101 macrocin O-methyltransferase
EC 2.1.1.102 demethylmacrocin O-methyltransferase
EC 2.1.1.103 phosphoethanolamine N-methyltransferase
EC 2.1.1.104 caffeoyl-CoA O-methyltransferase
EC 2.1.1.105 N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase
EC 2.1.1.106 tryptophan 2-C-methyltransferase
EC 2.1.1.107 uroporphyrinogen-III C-methyltransferase
EC 2.1.1.108 6-hydroxymellein O-methyltransferase
EC 2.1.1.109 demethylsterigmatocystin 6-O-methyltransferase
EC 2.1.1.110 sterigmatocystin 8-O-methyltransferase
EC 2.1.1.111 anthranilate N-methyltransferase
EC 2.1.1.112 glucuronoxylan 4-O-methyltransferase
EC 2.1.1.113 site-specific DNA-methyltransferase (cytosine-N4-specific)
EC 2.1.1.114 hexaprenyldihydroxybenzoate methyltransferase
EC 2.1.1.115 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase
EC 2.1.1.116 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase
EC 2.1.1.117 (S)-scoulerine 9-O-methyltransferase
EC 2.1.1.118 columbamine O-methyltransferase
EC 2.1.1.119 10-hydroxydihydrosanguinarine 10-O-methyltransferase
EC 2.1.1.120 12-hydroxydihydrochelirubine 12-O-methyltransferase
EC 2.1.1.121 6-O-methylnorlaudanosoline 5'-O-methyltransferase
EC 2.1.1.122 (S)-tetrahydroprotoberberine N-methyltransferase
EC 2.1.1.123 [cytochrome c]-methionine S-methyltransferase
EC 2.1.1.124 [cytochrome c]-arginine N-methyltransferase
EC 2.1.1.125 histone-arginine N-methyltransferase
EC 2.1.1.126 [myelin basic protein]-arginine N-methyltransferase
EC 2.1.1.127 [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase
EC 2.1.1.128 (RS)-norcoclaurine 6-O-methyltransferase
EC 2.1.1.129 inositol 4-methyltransferase
EC 2.1.1.130 precorrin-2 C20-methyltransferase
EC 2.1.1.131 precorrin-3B C17-methyltransferase
EC 2.1.1.132 precorrin-6Y C5,15-methyltransferase (decarboxylating)
EC 2.1.1.133 precorrin-4 C11-methyltransferase
EC 2.1.1.134 now with EC 2.1.1.129
EC 2.1.1.135 now EC 1.16.1.8
EC 2.1.1.136 chlorophenol O-methyltransferase
EC 2.1.1.137 arsenite methyltransferase
EC 2.1.1.138 deleted
EC 2.1.1.139 3'-demethylstaurosporine O-methyltransferase
EC 2.1.1.140 (S)-coclaurine-N-methyltransferase
EC 2.1.1.141 jasmonate O-methyltransferase
EC 2.1.1.142cycloartenol 24-C-methyltransferase
EC 2.1.1.14324-methylenesterol C-methyltransferase
EC 2.1.1.144 trans-aconitate 2-methyltransferase
EC 2.1.1.145 trans-aconitate 3-methyltransferase
EC 2.1.1.146 (iso)eugenol O-methyltransferase
EC 2.1.1.147 corydaline synthase
EC 2.1.1.148 thymidylate synthase (FAD)
EC 2.1.1.149 myricetin O-methyltransferase
EC 2.1.1.150 isoflavone 7-O-methyltransferase
EC 2.1.1.151 cobalt-factor II C20-methyltransferase
EC 2.1.1.152 precorrin-6A synthase (deacetylating)
EC 2.1.1.153 vitexin 2"-O-rhamnoside 7-O-methyltransferase
EC 2.1.1.154 isoliquiritigenin 2'-O-methyltransferase
EC 2.1.1.155 kaempferol 4'-O-methyltransferase
EC 2.1.1.156 glycine/sarcosine N-methyltransferase
EC 2.1.1.157 sarcosine/dimethylglycine N-methyltransferase
EC 2.1.1.158 7-methylxanthosine synthase
EC 2.1.1.159 theobromine synthase
EC 2.1.1.160 caffeine synthase
EC 2.1.1.161 dimethylglycine N-methyltransferase
EC 2.1.1.162 glycine/sarcosine/dimethylglycine N-methyltransferase
EC 2.1.1.163 demethylmenaquinone methyltransferase
EC 2.1.1.164 demethylrebeccamycin-D-glucose O-methyltransferase
EC 2.1.1.165 methyl halide transferase
EC 2.1.2 Hydroxymethyl-, Formyl- and Related Transferases
EC 2.1.2.1 glycine hydroxymethyltransferase
EC 2.1.2.2 phosphoribosylglycinamide formyltransferase
EC 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
EC 2.1.2.4 glycine formiminotransferase
EC 2.1.2.5 glutamate formiminotransferase
EC 2.1.2.6 deleted, included in EC 2.1.2.5
EC 2.1.2.7 D-alanine 2-hydroxymethyltransferase
EC 2.1.2.8 deoxycytidylate 5-hydroxymethyltransferase
EC 2.1.2.9 methionyl-tRNA formyltransferase
EC 2.1.2.10 aminomethyltransferase
EC 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase
EC 2.1.2.12 now EC 2.1.1.74
EC 2.1.3 Carboxyl- and Carbamoyltransferases
EC 2.1.3.1 methylmalonyl-CoA carboxyltransferase
EC 2.1.3.2 aspartate carbamoyltransferase
EC 2.1.3.3 ornithine carbamoyltransferase
EC 2.1.3.4 deleted
EC 2.1.3.5 oxamate carbamoyltransferase
EC 2.1.3.6 putrescine carbamoyltransferase
EC 2.1.3.7 3-hydroxymethylcephem carbamoyltransferase
EC 2.1.3.8 lysine carbamoyltransferase
EC 2.1.3.9 N-acetylornithine carbamoyltransferase
EC 2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase
EC 2.1.3.11 N-succinylornithine carbamoyltransferase
EC 2.1.4 Amidinotransferases
EC 2.1.4.1 glycine amidinotransferase
EC 2.1.4.2 scyllo-inosamine-4-phosphate amidinotransferase
EC 2.2 Transferring aldehyde or ketonic groups

EC 2.2.1 Transketolases and Transaldolases

EC 2.2.1.1 transketolase
EC 2.2.1.2 transaldolase
EC 2.2.1.3 formaldehyde transketolase
EC 2.2.1.4 acetoin—ribose-5-phosphate transaldolase
EC 2.2.1.5 2-hydroxy-3-oxoadipate synthase
EC 2.2.1.6 acetolactate synthase
EC 2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase
EC 2.2.1.8 fluorothreonine transaldolase
EC 2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid
synthase

EC 2.3 Acyltransferases

EC 2.3.1 Transferring groups other than amino-acyl groups


EC 2.3.1.1 amino-acid N-acetyltransferase
EC 2.3.1.2 imidazole N-acetyltransferase
EC 2.3.1.3 glucosamine N-acetyltransferase
EC 2.3.1.4 glucosamine-phosphate N-acetyltransferase
EC 2.3.1.5 arylamine N-acetyltransferase
EC 2.3.1.6 choline O-acetyltransferase
EC 2.3.1.7 carnitine O-acetyltransferase
EC 2.3.1.8 phosphate acetyltransferase
EC 2.3.1.9 acetyl-CoA C-acetyltransferase
EC 2.3.1.10 hydrogen-sulfide S-acetyltransferase
EC 2.3.1.11 thioethanolamine S-acetyltransferase
EC 2.3.1.12 dihydrolipoyllysine-residue acetyltransferase
EC 2.3.1.13 glycine N-acyltransferase
EC 2.3.1.14 glutamine N-phenylacetyltransferase
EC 2.3.1.15 glycerol-3-phosphate O-acyltransferase
EC 2.3.1.16 acetyl-CoA C-acyltransferase
EC 2.3.1.17 aspartate N-acetyltransferase
EC 2.3.1.18 galactoside O-acetyltransferase
EC 2.3.1.19 phosphate butyryltransferase
EC 2.3.1.20 diacylglycerol O-acyltransferase
EC 2.3.1.21 carnitine O-palmitoyltransferase
EC 2.3.1.22 2-acylglycerol O-acyltransferase
EC 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase
EC 2.3.1.24 sphingosine N-acyltransferase
EC 2.3.1.25 plasmalogen synthase
EC 2.3.1.26 sterol O-acyltransferase
EC 2.3.1.27 cortisol O-acetyltransferase
EC 2.3.1.28 chloramphenicol O-acetyltransferase
EC 2.3.1.29 glycine C-acetyltransferase
EC 2.3.1.30 serine O-acetyltransferase
EC 2.3.1.31 homoserine O-acetyltransferase
EC 2.3.1.32 lysine N-acetyltransferase
EC 2.3.1.33 histidine N-acetyltransferase
EC 2.3.1.34 D-tryptophan N-acetyltransferase
EC 2.3.1.35 glutamate N-acetyltransferase
EC 2.3.1.36 D-amino-acid N-acetyltransferase
EC 2.3.1.37 5-aminolevulinate synthase
EC 2.3.1.38 [acyl-carrier-protein] S-acetyltransferase
EC 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
EC 2.3.1.40 acyl-[acyl-carrier-protein]—phospholipid O-acyltransferase
EC 2.3.1.41 β-ketoacyl-acyl-carrier-protein synthase I
EC 2.3.1.42 glycerone-phosphate O-acyltransferase
EC 2.3.1.43 phosphatidylcholine—sterol O-acyltransferase
EC 2.3.1.44 N-acetylneuraminate 4-O-acetyltransferase
EC 2.3.1.45 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase
EC 2.3.1.46 homoserine O-succinyltransferase
EC 2.3.1.47 8-amino-7-oxononanoate synthase
EC 2.3.1.48 histone acetyltransferase
EC 2.3.1.49 deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase
EC 2.3.1.50 serine C-palmitoyltransferase
EC 2.3.1.51 1-acylglycerol-3-phosphate O-acyltransferase
EC 2.3.1.52 2-acylglycerol-3-phosphate O-acyltransferase
EC 2.3.1.53 phenylalanine N-acetyltransferase
EC 2.3.1.54 formate C-acetyltransferase
EC 2.3.1.55 now EC 2.3.1.82
EC 2.3.1.56 aromatic-hydroxylamine O-acetyltransferase
EC 2.3.1.57 diamine N-acetyltransferase
EC 2.3.1.58 2,3-diaminopropionate N-oxalyltransferase
EC 2.3.1.59 gentamicin 2'-N-acetyltransferase
EC 2.3.1.60 gentamicin 3'-N-acetyltransferase
EC 2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
EC 2.3.1.62 2-acylglycerophosphocholine O-acyltransferase
EC 2.3.1.63 1-alkylglycerophosphocholine O-acyltransferase
EC 2.3.1.64 agmatine N4-coumaroyltransferase
EC 2.3.1.65 bile acid-CoA:amino acid N-acyltransferase
EC 2.3.1.66 leucine N-acetyltransferase
EC 2.3.1.67 1-alkylglycerophosphocholine O-acetyltransferase
EC 2.3.1.68 glutamine N-acyltransferase
EC 2.3.1.69 monoterpenol O-acetyltransferase
EC 2.3.1.70 deleted
EC 2.3.1.71 glycine N-benzoyltransferase
EC 2.3.1.72 indoleacetylglucose—inositol O-acyltransferase
EC 2.3.1.73 diacylglycerol—sterol O-acyltransferase
EC 2.3.1.74 naringenin-chalcone synthase
EC 2.3.1.75 long-chain-alcohol O-fatty-acyltransferase
EC 2.3.1.76 retinol O-fatty-acyltransferase
EC 2.3.1.77 triacylglycerol—sterol O-acyltransferase
EC 2.3.1.78 heparan-α-glucosaminide N-acetyltransferase
EC 2.3.1.79 maltose O-acetyltransferase
EC 2.3.1.80 cysteine-S-conjugate N-acetyltransferase
EC 2.3.1.81 aminoglycoside N3'-acetyltransferase
EC 2.3.1.82 aminoglycoside N6'-acetyltransferase
EC 2.3.1.83 phosphatidylcholine—dolichol O-acyltransferase
EC 2.3.1.84 alcohol O-acetyltransferase
EC 2.3.1.85 fatty-acid synthase
EC 2.3.1.86 fatty-acyl-CoA synthase
EC 2.3.1.87 aralkylamine N-acetyltransferase
EC 2.3.1.88 peptide α-N-acetyltransferase
EC 2.3.1.89 tetrahydrodipicolinate N-acetyltransferase
EC 2.3.1.90 β-glucogallin O-galloyltransferase
EC 2.3.1.91 sinapoylglucose—choline O-sinapoyltransferase
EC 2.3.1.92 sinapoylglucose—malate O-sinapoyltransferase
EC 2.3.1.93 13-hydroxylupinine O-tigloyltransferase
EC 2.3.1.94 6-deoxyerythronolide-B synthase
EC 2.3.1.95 trihydroxystilbene synthase
EC 2.3.1.96 glycoprotein N-palmitoyltransferase
EC 2.3.1.97 glycylpeptide N-tetradecanoyltransferase
EC 2.3.1.98 chlorogenate—glucarate O-hydroxycinnamoyltransferase
EC 2.3.1.99 quinate O-hydroxycinnamoyltransferase
EC 2.3.1.100 [myelin-proteolipid] O-palmitoyltransferase
EC 2.3.1.101 formylmethanofuran—tetrahydromethanopterin N-formyltransferase
EC 2.3.1.102 N6-hydroxylysine O-acetyltransferase
EC 2.3.1.103 sinapoylglucose—sinapoylglucose O-sinapoyltransferase
EC 2.3.1.104 1-alkenylglycerophosphocholine O-acyltransferase
EC 2.3.1.105 alkylglycerophosphate 2-O-acetyltransferase
EC 2.3.1.106 tartronate O-hydroxycinnamoyltransferase
EC 2.3.1.107 deacetylvindoline O-acetyltransferase
EC 2.3.1.108 α-tubulin N-acetyltransferase
EC 2.3.1.109 arginine N-succinyltransferase
EC 2.3.1.110 tyramine N-feruloyltransferase
EC 2.3.1.111 mycocerosate synthase
EC 2.3.1.112 D-tryptophan N-malonyltransferase
EC 2.3.1.113 anthranilate N-malonyltransferase
EC 2.3.1.114 3,4-dichloroaniline N-malonyltransferase
EC 2.3.1.115 isoflavone-7-O-β-glucoside 6"-O-malonyltransferase
EC 2.3.1.116 flavonol-3-O-β-glucoside O-malonyltransferase
EC 2.3.1.117 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
EC 2.3.1.118 N-hydroxyarylamine O-acetyltransferase
EC 2.3.1.119 icosanoyl-CoA synthase
EC 2.3.1.120 deleted
EC 2.3.1.121 1-alkenylglycerophosphoethanolamine O-acyltransferase
EC 2.3.1.122 trehalose O-mycolyltransferase
EC 2.3.1.123 dolichol O-acyltransferase
EC 2.3.1.124 deleted
EC 2.3.1.125 1-alkyl-2-acetylglycerol O-acyltransferase
EC 2.3.1.126 isocitrate O-dihydroxycinnamoyltransferase
EC 2.3.1.127 ornithine N-benzoyltransferase
EC 2.3.1.128 ribosomal-protein-alanine N-acetyltransferase
EC 2.3.1.129 acyl-[acyl-carrier-protein]—UDP-N-acetylglucosamine O-
acyltransferase
EC 2.3.1.130 galactarate O-hydroxycinnamoyltransferase
EC 2.3.1.131 glucarate O-hydroxycinnamoyltransferase
EC 2.3.1.132 glucarolactone O-hydroxycinnamoyltransferase
EC 2.3.1.133 shikimate O-hydroxycinnamoyltransferase
EC 2.3.1.134 galactolipid O-acyltransferase
EC 2.3.1.135 phosphatidylcholine—retinol O-acyltransferase
EC 2.3.1.136 polysialic-acid O-acetyltransferase
EC 2.3.1.137 carnitine O-octanoyltransferase
EC 2.3.1.138 putrescine N-hydroxycinnamoyltransferase
EC 2.3.1.139 ecdysone O-acyltransferase
EC 2.3.1.140 rosmarinate synthase
EC 2.3.1.141 galactosylacylglycerol O-acyltransferase
EC 2.3.1.142 glycoprotein O-fatty-acyltransferase
EC 2.3.1.143 β-glucogallin—tetrakisgalloylglucose O-galloyltransferase
EC 2.3.1.144 anthranilate N-benzoyltransferase
EC 2.3.1.145 piperidine N-piperoyltransferase
EC 2.3.1.146 pinosylvin synthase
EC 2.3.1.147 glycerophospholipid arachidonoyl-transferase (CoA-independent)
EC 2.3.1.148 glycerophospholipid acyltransferase (CoA-dependent)
EC 2.3.1.149 platelet-activating factor acetyltransferase
EC 2.3.1.150 salutaridinol 7-O-acetyltransferase
EC 2.3.1.151 benzophenone synthase
EC 2.3.1.152 alcohol O-cinnamoyltransferase
EC 2.3.1.153 anthocyanin 5-aromatic acyltransferase
EC 2.3.1.154 propionyl-CoA C2-trimethyltridecanoyltransferase
EC 2.3.1.155 acetyl-CoA C-myristoyltransferase
EC 2.3.1.156 phloroisovalerophenone synthase
EC 2.3.1.157 glucosamine-1-phosphate N-acetyltransferase
EC 2.3.1.158 phospholipid:diacylglycerol acyltransferase
EC 2.3.1.159 acridone synthase
EC 2.3.1.160 vinorine synthase
EC 2.3.1.161 lovastatin nonaketide synthase
EC 2.3.1.162 taxadien-5α-ol O-acetyltransferase
EC 2.3.1.163 10-hydroxytaxane O-acetyltransferase
EC 2.3.1.164 isopenicillin-N N-acyltransferase
EC 2.3.1.165 6-methylsalicylic acid synthase
EC 2.3.1.166 2α-hydroxytaxane 2-O-benzoyltransferase
EC 2.3.1.167 10-deacetylbaccatin III 10-O-acetyltransferase
EC 2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
EC 2.3.1.169 CO-methylating acetyl-CoA synthase
EC 2.3.1.170 6'-deoxychalcone synthase
EC 2.3.1.171 anthocyanin 6"-O-malonyltransferase
EC 2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase
EC 2.3.1.173 flavonol-3-O-triglucoside O-coumaroyltransferase
EC 2.3.1.174 3-oxoadipyl-CoA thiolase
EC 2.3.1.175 deacetylcephalosporin-C acetyltransferase
EC 2.3.1.176 propanoyl-CoA C-acyltransferase
EC 2.3.1.177 biphenyl synthase
EC 2.3.1.178 diaminobutyrate acetyltransferase
EC 2.3.1.179 β-ketoacyl-acyl-carrier-protein synthase II
EC 2.3.1.180 β-ketoacyl-acyl-carrier-protein synthase III
EC 2.3.1.181 lipoyl(octanoyl) transferase
EC 2.3.1.182 (R)-citramalate synthase
EC 2.3.1.183 phosphinothricin acetyltransferase
EC 2.3.1.184 acyl-homoserine-lactone synthase
EC 2.3.1.185 tropine acyltransferase
EC 2.3.1.186 pseudotropine acyltransferase
EC 2.3.1.187 acetyl-S-ACP:malonate ACP transferase
EC 2.3.1.188 ω-hydroxypalmitate O-feruloyl transferase
EC 2.3.1.189 mycothiol synthase
EC 2.3.2 Aminoacyltransferases
EC 2.3.2.1 D-glutamyltransferase
EC 2.3.2.2 γ-glutamyltransferase
EC 2.3.2.3 lysyltransferase
EC 2.3.2.4 γ-glutamylcyclotransferase
EC 2.3.2.5 glutaminyl-peptide cyclotransferase
EC 2.3.2.6 leucyltransferase
EC 2.3.2.7 aspartyltransferase
EC 2.3.2.8 arginyltransferase
EC 2.3.2.9 agaritine γ-glutamyltransferase
EC 2.3.2.10 UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase
EC 2.3.2.11 alanylphosphatidylglycerol synthase
EC 2.3.2.12 peptidyltransferase
EC 2.3.2.13 protein-glutamine γ-glutamyltransferase
EC 2.3.2.14 D-alanine γ-glutamyltransferase
EC 2.3.2.15 glutathione γ-glutamylcysteinyltransferase
EC 2.3.3 Acyl groups converted into alkyl on transfer
EC 2.3.3.1 citrate (Si)-synthase
EC 2.3.3.2 decylcitrate synthase
EC 2.3.3.3 citrate (Re)-synthase
EC 2.3.3.4 decylhomocitrate synthase
EC 2.3.3.5 2-methylcitrate synthase
EC 2.3.3.6 2-ethylmalate synthase
EC 2.3.3.7 3-ethylmalate synthase
EC 2.3.3.8 ATP citrate synthase
EC 2.3.3.9 malate synthase
EC 2.3.3.10 hydroxymethylglutaryl-CoA synthase
EC 2.3.3.11 2-hydroxyglutarate synthase
EC 2.3.3.12 3-propylmalate synthase
EC 2.3.3.13 2-isopropylmalate synthase
EC 2.3.3.14 homocitrate synthase
EC 2.3.3.15 sulfoacetaldehyde acetyltransferase
EC 2.4 Glycosyltransferases
EC 2.4.1 Hexosyltransferases
EC 2.4.1.1 phosphorylase
EC 2.4.1.2 dextrin dextranase
EC 2.4.1.3 deleted, included in EC 2.4.1.25
EC 2.4.1.4 amylosucrase
EC 2.4.1.5 dextransucrase
EC 2.4.1.6 deleted
EC 2.4.1.7 sucrose phosphorylase
EC 2.4.1.8 maltose phosphorylase
EC 2.4.1.9 inulosucrase
EC 2.4.1.10 levansucrase
EC 2.4.1.11 glycogen(starch) synthase
EC 2.4.1.12 cellulose synthase (UDP-forming)
EC 2.4.1.13 sucrose synthase
EC 2.4.1.14 sucrose-phosphate synthase
EC 2.4.1.15 α,α-trehalose-phosphate synthase (UDP-forming)
EC 2.4.1.16 chitin synthase
EC 2.4.1.17 glucuronosyltransferase
EC 2.4.1.18 1,4-α-glucan branching enzyme
EC 2.4.1.19 cyclomaltodextrin glucanotransferase
EC 2.4.1.20 cellobiose phosphorylase
EC 2.4.1.21 starch synthase
EC 2.4.1.22 lactose synthase
EC 2.4.1.23 sphingosine β-galactosyltransferase
EC 2.4.1.24 1,4-α-glucan 6-α-glucosyltransferase
EC 2.4.1.25 4-α-glucanotransferase
EC 2.4.1.26 DNA α-glucosyltransferase
EC 2.4.1.27 DNA β-glucosyltransferase
EC 2.4.1.28 glucosyl-DNA β-glucosyltransferase
EC 2.4.1.29 cellulose synthase (GDP-forming)
EC 2.4.1.30 1,3-β-oligoglucan phosphorylase
EC 2.4.1.31 laminaribiose phosphorylase
EC 2.4.1.32 glucomannan 4-β-mannosyltransferase
EC 2.4.1.33 alginate synthase
EC 2.4.1.34 1,3-β-glucan synthase
EC 2.4.1.35 phenol β-glucosyltransferase
EC 2.4.1.36 α,α-trehalose-phosphate synthase (GDP-forming)
EC 2.4.1.37 fucosylgalactoside 3-α-galactosyltransferase
EC 2.4.1.38 β-N-acetylglucosaminylglycopeptide β-1,4-galactosyltransferase
EC 2.4.1.39 steroid N-acetylglucosaminyltransferase
EC 2.4.1.40 glycoprotein-fucosylgalactoside α-N-acetylgalactosaminyltransferase
EC 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase
EC 2.4.1.42 deleted, included in EC 2.4.1.17
EC 2.4.1.43 polygalacturonate 4-α-galacturonosyltransferase
EC 2.4.1.44 lipopolysaccharide 3-α-galactosyltransferase
EC 2.4.1.45 2-hydroxyacylsphingosine 1-β-galactosyltransferase
EC 2.4.1.46 monogalactosyldiacylglycerol synthase
EC 2.4.1.47 N-acylsphingosine galactosyltransferase
EC 2.4.1.48 heteroglycan α-mannosyltransferase
EC 2.4.1.49 cellodextrin phosphorylase
EC 2.4.1.50 procollagen galactosyltransferase
EC 2.4.1.51 now covered by EC 2.4.1.101, EC 2.4.1.143, EC 2.4.1.144 and EC
2.4.1.145
EC 2.4.1.52 poly(glycerol-phosphate) α-glucosyltransferase
EC 2.4.1.53 poly(ribitol-phosphate) β-glucosyltransferase
EC 2.4.1.54 undecaprenyl-phosphate mannosyltransferase
EC 2.4.1.55 now EC 2.7.8.14
EC 2.4.1.56 lipopolysaccharide N-acetylglucosaminyltransferase
EC 2.4.1.57 phosphatidylinositol α-mannosyltransferase
EC 2.4.1.58 lipopolysaccharide glucosyltransferase I
EC 2.4.1.59 deleted, included in EC 2.4.1.17
EC 2.4.1.60 abequosyltransferase
EC 2.4.1.61 deleted, included in EC 2.4.1.17
EC 2.4.1.62 ganglioside galactosyltransferase
EC 2.4.1.63 linamarin synthase
EC 2.4.1.64 α,α-trehalose phosphorylase
EC 2.4.1.65 3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase
EC 2.4.1.66 procollagen glucosyltransferase
EC 2.4.1.67 galactinol—raffinose galactosyltransferase
EC 2.4.1.68 glycoprotein 6-α-L-fucosyltransferase
EC 2.4.1.69 galactoside 2-α-L-fucosyltransferase
EC 2.4.1.70 poly(ribitol-phosphate) N-acetylglucosaminyltransferase
EC 2.4.1.71 arylamine glucosyltransferase
EC 2.4.1.72 now EC 2.4.2.24
EC 2.4.1.73 lipopolysaccharide glucosyltransferase II
EC 2.4.1.74 glycosaminoglycan galactosyltransferase
EC 2.4.1.75 deleted entry
EC 2.4.1.76 deleted, included in EC 2.4.1.17
EC 2.4.1.77 deleted, included in EC 2.4.1.17
EC 2.4.1.78 phosphopolyprenol glucosyltransferase
EC 2.4.1.79 globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase
EC 2.4.1.80 ceramide glucosyltransferase
EC 2.4.1.81 flavone 7-O-β-glucosyltransferase
EC 2.4.1.82 galactinol—sucrose galactosyltransferase
EC 2.4.1.83 dolichyl-phosphate β-D-mannosyltransferase
EC 2.4.1.84 deleted, included in EC 2.4.1.17
EC 2.4.1.85 cyanohydrin β-glucosyltransferase
EC 2.4.1.86 glucosaminylgalactosylglucosylceramide β-galactosyltransferase
EC 2.4.1.87 N-acetyllactosaminide 3-α-galactosyltransferase
EC 2.4.1.88 globoside α-N-acetylgalactosaminyltransferase
EC 2.4.1.89 deleted, included in EC 2.4.1.69
EC 2.4.1.90 N-acetyllactosamine synthase
EC 2.4.1.91 flavonol 3-O-glucosyltransferase
EC 2.4.1.92 (N-acetylneuraminyl)-galactosylglucosylceramide N-
acetylgalactosaminyltransferase
EC 2.4.1.93 now EC 4.2.2.18
EC 2.4.1.94 protein N-acetylglucosaminyltransferase
EC 2.4.1.95 bilirubin-glucuronoside glucuronosyltransferase
EC 2.4.1.96 sn-glycerol-3-phosphate 1-galactosyltransferase
EC 2.4.1.97 1,3-β-D-glucan phosphorylase
EC 2.4.1.98 deleted, included in EC 2.4.1.90
EC 2.4.1.99 sucrose:sucrose fructosyltransferase
EC 2.4.1.100 2,1-fructan:2,1-fructan 1-fructosyltransferase
EC 2.4.1.101 α-1,3-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase
EC 2.4.1.102 β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,6-N-
acetylglucosaminyltransferase
EC 2.4.1.103 alizarin 2-β-glucosyltransferase
EC 2.4.1.104 o-dihydroxycoumarin 7-O-glucosyltransferase
EC 2.4.1.105 vitexin β-glucosyltransferase
EC 2.4.1.106 isovitexin β-glucosyltransferase
EC 2.4.1.107 deleted, included in EC 2.4.1.17
EC 2.4.1.108 deleted, included in EC 2.4.1.17
EC 2.4.1.109 dolichyl-phosphate-mannose-protein mannosyltransferase
EC 2.4.1.110 tRNA-queuosine β-mannosyltransferase
EC 2.4.1.111 coniferyl-alcohol glucosyltransferase
EC 2.4.1.112 deleted now EC 2.4.1.186
EC 2.4.1.113 α-1,4-glucan-protein synthase (ADP-forming)
EC 2.4.1.114 2-coumarate O-β-glucosyltransferase
EC 2.4.1.115 anthocyanidin 3-O-glucosyltransferase
EC 2.4.1.116 cyanidin 3-O-rutinoside 5-O-glucosyltransferase
EC 2.4.1.117 dolichyl-phosphate β-glucosyltransferase
EC 2.4.1.118 cytokinin 7-β-glucosyltransferase
EC 2.4.1.119 dolichyl-diphosphooligosaccharide—protein glycotransferase
EC 2.4.1.120 sinapate 1-glucosyltransferase
EC 2.4.1.121 indole-3-acetate β-glucosyltransferase
EC 2.4.1.122 glycoprotein-N-acetylgalactosamine 3-β-galactosyltransferase
EC 2.4.1.123 inositol 3-α-galactosyltransferase
EC 2.4.1.124 now included with EC 2.4.1.87
EC 2.4.1.125 sucrose—1,6-α-glucan 3(6)-α-glucosyltransferase
EC 2.4.1.126 hydroxycinnamate 4-β-glucosyltransferase
EC 2.4.1.127 monoterpenol β-glucosyltransferase
EC 2.4.1.128 scopoletin glucosyltransferase
EC 2.4.1.129 peptidoglycan glycosyltransferase
EC 2.4.1.130 dolichyl-phosphate-mannose—glycolipid α-mannosyltransferase
EC 2.4.1.131 glycolipid 2-α-mannosyltransferase
EC 2.4.1.132 glycolipid 3-α-mannosyltransferase
EC 2.4.1.133 xylosylprotein 4-β-galactosyltransferase
EC 2.4.1.134 galactosylxylosylprotein 3-β-galactosyltransferase
EC 2.4.1.135 galactosylgalactosylxylosylprotein 3-β-glucuronosyltransferase
EC 2.4.1.136 gallate 1-β-glucosyltransferase
EC 2.4.1.137 sn-glycerol-3-phosphate 2-α-galactosyltransferase
EC 2.4.1.138 mannotetraose 2-α-N-acetylglucosaminyltransferase
EC 2.4.1.139 maltose synthase
EC 2.4.1.140 alternansucrase
EC 2.4.1.141 N-acetylglucosaminyldiphosphodolichol N-
acetylglucosaminyltransferase
EC 2.4.1.142 chitobiosyldiphosphodolichol β-mannosyltransferase
EC 2.4.1.143 α-1,6-mannosyl-glycoprotein 2-β-N-acetylglucosaminyltransferase
EC 2.4.1.144 β-1,4-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
EC 2.4.1.145 α-1,3-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
EC 2.4.1.146 β-1,3-galactosyl-O-glycosyl-glycoprotein β-1,3-N-
acetylglucosaminyltransferase
EC 2.4.1.147 acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,3-N-
acetylglucosaminyltransferase
EC 2.4.1.148 acetylgalactosaminyl-O-glycosyl-glycoprotein β-1,6-N-
acetylglucosaminyltransferase
EC 2.4.1.149 N-acetyllactosaminide β-1,3-N-acetylglucosaminyltransferase
EC 2.4.1.150 N-acetyllactosaminide β-1,6-N-acetylglucosaminyl-transferase
EC 2.4.1.151 included with EC 2.4.1.87
EC 2.4.1.152 galactoside 3-fucosyltransferase
EC 2.4.1.153 dolichyl-phosphate α-N-acetylglucosaminyltransferase
EC 2.4.1.154 now EC 2.4.1.79
EC 2.4.1.155 α-1,6-mannosyl-glycoprotein 6-β-N-acetylglucosaminyltransferase
EC 2.4.1.156 indolylacetyl-myo-inositol galactosyltransferase
EC 2.4.1.157 1,2-diacylglycerol 3-glucosyltransferase
EC 2.4.1.158 13-hydroxydocosanoate 13-β-glucosyltransferase
EC 2.4.1.159 flavonol-3-O-glucoside L-rhamnosyltransferase
EC 2.4.1.160 pyridoxine 5'-O-β-D-glucosyltransferase
EC 2.4.1.161 oligosaccharide 4-α-D-glucosyltransferase
EC 2.4.1.162 aldose β-D-fructosyltransferase
EC 2.4.1.163 β-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,3-
acetylglucosaminyltransferase
EC 2.4.1.164 galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,6-N-
acetylglucosaminyltransferase
EC 2.4.1.165 N-acetylneuraminylgalactosylglucosylceramide β-1,4-N-
acetylgalactosaminyltransferase
EC 2.4.1.166 raffinose—raffinose α-galactosyltransferase
EC 2.4.1.167 sucrose 6F-α-galactosyltransferase
EC 2.4.1.168 xyloglucan 4-glucosyltransferase
EC 2.4.1.169 now EC 2.4.2.39
EC 2.4.1.170 isoflavone 7-O-glucosyltransferase
EC 2.4.1.171 methyl-ONN-azoxymethanol β-D-glucosyltransferase
EC 2.4.1.172 salicyl-alcohol β-D-glucosyltransferase
EC 2.4.1.173 sterol 3β-glucosyltransferase
EC 2.4.1.174 glucuronylgalactosylproteoglycan 4-β-N-
acetylgalactosaminyltransferase
EC 2.4.1.175 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-β-N-
acetylgalactosaminyltransferase
EC 2.4.1.176 gibberellin β-D-glucosyltransferase
EC 2.4.1.177 cinnamate β-D-glucosyltransferase
EC 2.4.1.178 hydroxymandelonitrile glucosyltransferase
EC 2.4.1.179 lactosylceramide β-1,3-galactosyltransferase
EC 2.4.1.180 lipopolysaccharide N-acetylmannosaminouronosyltransferase
EC 2.4.1.181 hydroxyanthraquinone glucosyltransferase
EC 2.4.1.182 lipid-A-disaccharide synthase
EC 2.4.1.183 α-1,3-glucan synthase
EC 2.4.1.184 galactolipid galactosyltransferase
EC 2.4.1.185 flavanone 7-O-β-glucosyltransferase
EC 2.4.1.186 glycogenin glucosyltransferase
EC 2.4.1.187 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-β-D-
mannosaminyltransferase
EC 2.4.1.188 N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase
EC 2.4.1.189 luteolin 7-O-glucuronosyltransferase
EC 2.4.1.190 luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase
EC 2.4.1.191 luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase
EC 2.4.1.192 nuatigenin 3β-glucosyltransferase
EC 2.4.1.193 sarsapogenin 3β-glucosyltransferase
EC 2.4.1.194 4-hydroxybenzoate 4-O-β-D-glucosyltransferase
EC 2.4.1.195 N-hydroxythioamide S-β-glucosyltransferase
EC 2.4.1.196 nicotinate glucosyltransferase
EC 2.4.1.197 high-mannose-oligosaccharide β-1,4-N-acetylglucosaminyltransferase
EC 2.4.1.198 phosphatidylinositol N-acetylglucosaminyltransferase
EC 2.4.1.199 β-mannosylphosphodecaprenol—mannooligosaccharide 6-
mannosyltransferase
EC 2.4.1.200 now EC 4.2.2.17
EC 2.4.1.201 α-1,6-mannosyl-glycoprotein 4-β-N-acetylglucosaminyltransferase
EC 2.4.1.202 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2 -D-
glucosyltransferase
EC 2.4.1.203 trans-zeatin O-β-D-glucosyltransferase
EC 2.4.1.204 now EC 2.4.2.40
EC 2.4.1.205 galactogen 6β-galactosyltransferase
EC 2.4.1.206 lactosylceramide 1,3-N-acetyl-β-D-glucosaminyltransferase
EC 2.4.1.207 xyloglucan:xyloglucosyl transferase
EC 2.4.1.208 diglucosyl diacylglycerol synthase
EC 2.4.1.209 cis-p-coumarate glucosyltransferase
EC 2.4.1.210 limonoid glucosyltransferase
EC 2.4.1.211 1,3-β-galactosyl-N-acetylhexosamine phosphorylase
EC 2.4.1.212 hyaluronan synthase
EC 2.4.1.213 glucosylglycerol-phosphate synthase
EC 2.4.1.214 glycoprotein 3-α-L-fucosyltransferase
EC 2.4.1.215 cis-zeatin O-β-D-glucosyltransferase
EC 2.4.1.216 trehalose 6-phosphate phosphorylase
EC 2.4.1.217 mannosyl-3-phosphoglycerate synthase
EC 2.4.1.218 hydroquinone glucosyltransferase
EC 2.4.1.219 vomilenine glucosyltransferase
EC 2.4.1.220 indoxyl-UDPG glucosyltransferase
EC 2.4.1.221 peptide-O-fucosyltransferase
EC 2.4.1.222 O-fucosylpeptide 3-β-N-acetylglucosaminyltransferase
EC 2.4.1.223 glucuronyl-galactosyl-proteoglycan 4-α-N-
acetylglucosaminyltransferase
EC 2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-α-N-
acetylglucosaminyltransferase
EC 2.4.1.225 N-acetylglucosaminyl-proteoglycan 4-β-glucuronosyltransferase
EC 2.4.1.226 N-acetylgalactosaminyl-proteoglycan 3-β-glucuronosyltransferase
EC 2.4.1.227 undecaprenyldiphospho-muramoylpentapeptide β-N-
acetylglucosaminyltransferase
EC 2.4.1.228 lactosylceramide 4-α-galactosyltransferase
EC 2.4.1.229 [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase
EC 2.4.1.230 kojibiose phosphorylase
EC 2.4.1.231 α,α-trehalose phosphorylase (configuration-retaining)
EC 2.4.1.232 glycolipid 6-α-mannosyltransferase
EC 2.4.1.233 deleted now EC 2.4.1.115
EC 2.4.1.234 kaempferol 3-O-galactosyltransferase
EC 2.4.1.235 now EC 2.4.1.116
EC 2.4.1.236 flavanone 7-O-glucoside 2"-O-β-L-rhamnosyltransferase
EC 2.4.1.237 flavonol 7-O-β-glucosyltransferase
EC 2.4.1.238 anthocyanin 3'-O-β-glucosyltransferase
EC 2.4.1.239 flavonol-3-O-glucoside glucosyltransferase
EC 2.4.1.240 flavonol-3-O-glycoside glucosyltransferase
EC 2.4.1.241 digalactosyldiacylglycerol synthase
EC 2.4.1.242 NDP-glucose—starch glucosyltransferase
EC 2.4.1.243 6G-fructosyltransferase
EC 2.4.1.244 N-acetyl-β-glucosaminyl-glycoprotein 4-β-N-
acetylgalactosaminyltransferase
EC 2.4.1.245 α,α-trehalose synthase
EC 2.4.1.246 mannosylfructose-phosphate synthase
EC 2.4.1.247 β-D-galactosyl-(1→4)-L-rhamnose phosphorylase
EC 2.4.1.248 cycloisomaltooligosaccharide glucanotransferase
EC 2.4.1.249 delphinidin 3',5'-O-glucosyltransferase
EC 2.4.1.250 D-inositol-3-phosphate glycosyltransferase
EC 2.4.2 Pentosyltransferases
EC 2.4.2.1 purine-nucleoside phosphorylase
EC 2.4.2.2 pyrimidine-nucleoside phosphorylase
EC 2.4.2.3 uridine phosphorylase
EC 2.4.2.4 thymidine phosphorylase
EC 2.4.2.5 nucleoside ribosyltransferase
EC 2.4.2.6 nucleoside deoxyribosyltransferase
EC 2.4.2.7 adenine phosphoribosyltransferase
EC 2.4.2.8 hypoxanthine phosphoribosyltransferase
EC 2.4.2.9 uracil phosphoribosyltransferase
EC 2.4.2.10 orotate phosphoribosyltransferase
EC 2.4.2.11 nicotinate phosphoribosyltransferase
EC 2.4.2.12 nicotinamide phosphoribosyltransferase
EC 2.4.2.13 now EC 2.5.1.6
EC 2.4.2.14 amidophosphoribosyltransferase
EC 2.4.2.15 guanosine phosphorylase
EC 2.4.2.16 urate-ribonucleotide phosphorylase
EC 2.4.2.17 ATP phosphoribosyltransferase
EC 2.4.2.18 anthranilate phosphoribosyltransferase
EC 2.4.2.19 nicotinate-nucleotide diphosphorylase (carboxylating)
EC 2.4.2.20 dioxotetrahydropyrimidine phosphoribosyltransferase
EC 2.4.2.21 nicotinate-nucleotide—dimethylbenzimidazole
phosphoribosyltransferase
EC 2.4.2.22 xanthine phosphoribosyltransferase
EC 2.4.2.23 deoxyuridine phosphorylase
EC 2.4.2.24 1,4-β-D-xylan synthase
EC 2.4.2.25 flavone apiosyltransferase
EC 2.4.2.26 protein xylosyltransferase
EC 2.4.2.27 dTDP-dihydrostreptose—streptidine-6-phosphate
dihydrostreptosyltransferase
EC 2.4.2.28 S-methyl-5'-thioadenosine phosphorylase
EC 2.4.2.29 tRNA-guanine transglycosylase
EC 2.4.2.30 NAD+ ADP-ribosyltransferase
EC 2.4.2.31 NAD+—protein-arginine ADP-ribosyltransferase
EC 2.4.2.32 dolichyl-phosphate D-xylosyltransferase
EC 2.4.2.33 dolichyl-xylosyl-phosphate—protein xylosyltransferase
EC 2.4.2.34 indolylacetylinositol arabinosyltransferase
EC 2.4.2.35 flavonol-3-O-glycoside xylosyltransferase
EC 2.4.2.36 NAD+—diphthamide ADP-ribosyltransferase
EC 2.4.2.37 NAD+—dinitrogen-reductase ADP-D-ribosyltransferase
EC 2.4.2.38 glycoprotein 2-β-D-xylosyltransferase
EC 2.4.2.39 xyloglucan 6-xylosyltransferase
EC 2.4.2.40 zeatin O-β-D-xylosyltransferase
EC 2.4.2.41 xylogalacturonan β-1,3-xylosyltransferase
EC 2.4.2.42 UDP-D-xylose:β-D-glucoside α-1,3-D-xylosyltransferase
EC 2.4.99 Transferring other glycosyl groups
EC 2.4.99.1 β-galactoside α-2,6-sialyltransferase
EC 2.4.99.2 monosialoganglioside sialyltransferase
EC 2.4.99.3 α-N-acetylgalactosaminide α-2,6-sialyltransferase
EC 2.4.99.4 β-galactoside α-2,3-sialyltransferase
EC 2.4.99.5 galactosyldiacylglycerol α-2,3-sialyltransferase
EC 2.4.99.6 N-acetyllactosaminide α-2,3-sialyltransferase
EC 2.4.99.7 (α-N-acetylneuraminyl-2,3-β-galactosyl-1,3)-N-acetyl-galactosaminide
6-α-sialyltransferase
EC 2.4.99.8 α-N-acetylneuraminate α-2,8-sialyltransferase
EC 2.4.99.9 lactosylceramide α-2,3-sialyltransferase
EC 2.4.99.10 neolactotetraosylceramide α-2,3-sialyltransferase
EC 2.4.99.11 lactosylceramide α-2,6-N-sialyltransferase
EC 2.5 Transferring alkyl or aryl groups, other than methyl groups
EC 2.5.1 Transferring Alkyl or Aryl Groups, Other than Methyl Groups
EC 2.5.1.1 dimethylallyltranstransferase
EC 2.5.1.2 thiamine pyridinylase
EC 2.5.1.3 thiamine-phosphate diphosphorylase
EC 2.5.1.4 adenosylmethionine cyclotransferase
EC 2.5.1.5 galactose-6-sulfurylase
EC 2.5.1.6 methionine adenosyltransferase
EC 2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase
EC 2.5.1.8 transferred now EC 2.5.1.75
EC 2.5.1.9 riboflavin synthase
EC 2.5.1.10 geranyltranstransferase
EC 2.5.1.11 trans-octaprenyltranstransferase
EC 2.5.1.12 deleted, included in EC 2.5.1.18
EC 2.5.1.13 deleted, included in EC 2.5.1.18
EC 2.5.1.14 deleted, included in EC 2.5.1.18
EC 2.5.1.15 dihydropteroate synthase
EC 2.5.1.16 spermidine synthase
EC 2.5.1.17 cob(I)yrinic acid a,c-diamide adenosyltransferase
EC 2.5.1.18 glutathione transferase
EC 2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase
EC 2.5.1.20 rubber cis-polyprenylcistransferase
EC 2.5.1.21 squalene synthase
EC 2.5.1.22 spermine synthase
EC 2.5.1.23 sym-norspermidine synthase
EC 2.5.1.24 discadenine synthase
EC 2.5.1.25 tRNA-uridine aminocarboxypropyltransferase
EC 2.5.1.26 alkylglycerone-phosphate synthase
EC 2.5.1.27 adenylate dimethylallyltransferase
EC 2.5.1.28 dimethylallylcistransferase
EC 2.5.1.29 farnesyltranstransferase
EC 2.5.1.30 trans-hexaprenyltranstransferase
EC 2.5.1.31 di-trans,poly-cis-decaprenylcistransferase
EC 2.5.1.32 phytoene synthase
EC 2.5.1.33 trans-pentaprenyltranstransferase
EC 2.5.1.34 tryptophan dimethylallyltransferase
EC 2.5.1.35 aspulvinone dimethylallyltransferase
EC 2.5.1.36 trihydroxypterocarpan dimethylallyltransferase
EC 2.5.1.37 now EC 4.4.1.20
EC 2.5.1.38 isonocardicin synthase
EC 2.5.1.39 4-hydroxybenzoate nonaprenyltransferase
EC 2.5.1.40 now EC 4.2.3.9
EC 2.5.1.41 phosphoglycerol geranylgeranyltransferase
EC 2.5.1.42 geranylgeranylglycerol-phosphate geranylgeranyltransferase
EC 2.5.1.43 nicotianamine synthase
EC 2.5.1.44 homospermidine synthase
EC 2.5.1.45 homospermidine synthase (spermidine-specific)
EC 2.5.1.46 deoxyhypusine synthase
EC 2.5.1.47 cysteine synthase
EC 2.5.1.48 cystathionine γ-synthase
EC 2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase
EC 2.5.1.50 zeatin 9-aminocarboxyethyltransferase
EC 2.5.1.51 β-pyrazolylalanine synthase
EC 2.5.1.52 L-mimosine synthase
EC 2.5.1.53 uracilylalanine synthase
EC 2.5.1.54 3-deoxy-7-phosphoheptulonate synthase
EC 2.5.1.55 3-deoxy-8-phosphooctulonate synthase
EC 2.5.1.56 N-acetylneuraminate synthase
EC 2.5.1.57 N-acylneuraminate-9-phosphate synthase
EC 2.5.1.58 protein farnesyltransferase
EC 2.5.1.59 protein geranylgeranyltransferase type I
EC 2.5.1.60 protein geranylgeranyltransferase type II
EC 2.5.1.61 hydroxymethylbilane synthase
EC 2.5.1.62 chlorophyll synthase
EC 2.5.1.63 adenosyl-fluoride synthase
EC 2.5.1.64 transferred to EC 2.2.1.9 and EC 4.2.99.20
EC 2.5.1.65 O-phosphoserine sulfhydrylase
EC 2.5.1.66 N2-(2-carboxyethyl)arginine synthase
EC 2.5.1.67 chrysanthemyl diphosphate synthase
EC 2.5.1.68 Z-farnesyl diphosphate synthase
EC 2.5.1.69 lavandulyl diphosphate synthase
EC 2.5.1.70 naringenin 8-dimethylallyltransferase
EC 2.5.1.71 leachianone G 2"-dimethylallyltransferase
EC 2.5.1.72 quinolinate synthase
EC 2.5.1.73 O-phospho-L-seryl-tRNA:Cys-tRNA synthase
EC 2.5.1.74 1,4-dihydroxy-2-naphthoate polyprenyltransferase
EC 2.5.1.75 tRNA dimethylallyltransferase
EC 2.5.1.76 cysteate synthase
EC 2.6 Transferring nitrogenous groups
EC 2.6.1 Transaminases
EC 2.6.1.1 aspartate transaminase
EC 2.6.1.2 alanine transaminase
EC 2.6.1.3 cysteine transaminase
EC 2.6.1.4 glycine transaminase
EC 2.6.1.5 tyrosine transaminase
EC 2.6.1.6 leucine transaminase
EC 2.6.1.7 kynurenine—oxoglutarate transaminase
EC 2.6.1.8 2,5-diaminovalerate transaminase
EC 2.6.1.9 histidinol-phosphate transaminase
EC 2.6.1.10 deleted, included in EC 2.6.1.21
EC 2.6.1.11 acetylornithine transaminase
EC 2.6.1.12 alanine—oxo-acid transaminase
EC 2.6.1.13 ornithine aminotransferase
EC 2.6.1.14 asparagine—oxo-acid transaminase
EC 2.6.1.15 glutamine—pyruvate transaminase
EC 2.6.1.16 glutamine—fructose-6-phosphate transaminase (isomerizing)
EC 2.6.1.17 succinyldiaminopimelate transaminase
EC 2.6.1.18 β-alanine—pyruvate transaminase
EC 2.6.1.19 4-aminobutyrate transaminase
EC 2.6.1.20 deleted
EC 2.6.1.21 D-amino acid transaminase
EC 2.6.1.22 (S)-3-amino-2-methylpropionate transaminase
EC 2.6.1.23 4-hydroxyglutamate transaminase
EC 2.6.1.24 diiodotyrosine transaminase
EC 2.6.1.25 deleted, included in EC 2.6.1.24
EC 2.6.1.26 thyroid-hormone transaminase
EC 2.6.1.27 tryptophan transaminase
EC 2.6.1.28 tryptophan—phenylpyruvate transaminase
EC 2.6.1.29 diamine transaminase
EC 2.6.1.30 pyridoxamine—pyruvate transaminase
EC 2.6.1.31 pyridoxamine—oxaloacetate transaminase
EC 2.6.1.32 valine—3-methyl-2-oxovalerate transaminase
EC 2.6.1.33 dTDP-4-amino-4,6-dideoxy-D-glucose transaminase
EC 2.6.1.34 UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase
EC 2.6.1.35 glycine—oxaloacetate transaminase
EC 2.6.1.36 L-lysine 6-transaminase
EC 2.6.1.37 (2-aminoethyl)phosphonate—pyruvate transaminase
EC 2.6.1.38 histidine transaminase
EC 2.6.1.39 2-aminoadipate transaminase
EC 2.6.1.40 (R)-3-amino-2-methylpropionate—pyruvate transaminase
EC 2.6.1.41 D-methionine—pyruvate transaminase
EC 2.6.1.42 branched-chain-amino-acid transaminase
EC 2.6.1.43 aminolevulinate transaminase
EC 2.6.1.44 alanine—glyoxylate transaminase
EC 2.6.1.45 serine—glyoxylate transaminase
EC 2.6.1.46 diaminobutyrate—pyruvate transaminase
EC 2.6.1.47 alanine—oxomalonate transaminase
EC 2.6.1.48 5-aminovalerate transaminase
EC 2.6.1.49 dihydroxyphenylalanine transaminase
EC 2.6.1.50 glutamine—scyllo-inositol transaminase
EC 2.6.1.51 serine—pyruvate transaminase
EC 2.6.1.52 phosphoserine transaminase
EC 2.6.1.53 now EC 1.4.1.13
EC 2.6.1.54 pyridoxamine-phosphate transaminase
EC 2.6.1.55 taurine—2-oxoglutarate transaminase
EC 2.6.1.56 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase
EC 2.6.1.57 aromatic-amino-acid transaminase
EC 2.6.1.58 phenylalanine(histidine) transaminase
EC 2.6.1.59 dTDP-4-amino-4,6-dideoxygalactose transaminase
EC 2.6.1.60 aromatic-amino-acid—glyoxylate transaminase
EC 2.6.1.61 identical to EC 2.6.1.40
EC 2.6.1.62 adenosylmethionine—8-amino-7-oxononanoate transaminase
EC 2.6.1.63 kynurenine—glyoxylate transaminase
EC 2.6.1.64 glutamine—phenylpyruvate transaminase
EC 2.6.1.65 N6-acetyl-β-lysine transaminase
EC 2.6.1.66 valine—pyruvate transaminase
EC 2.6.1.67 2-aminohexanoate transaminase
EC 2.6.1.68 ornithine(lysine) transaminase
EC 2.6.1.69 now EC 2.6.1.11
EC 2.6.1.70 aspartate—phenylpyruvate transaminase
EC 2.6.1.71 lysine—pyruvate 6-transaminase
EC 2.6.1.72 D-4-hydroxyphenylglycine transaminase
EC 2.6.1.73 methionine—glyoxylate transaminase
EC 2.6.1.74 cephalosporin-C transaminase
EC 2.6.1.75 cysteine-conjugate transaminase
EC 2.6.1.76 diaminobutyrate—2-oxoglutarate transaminase
EC 2.6.1.77 taurine—pyruvate aminotransferase
EC 2.6.1.78 aspartate—prephenate aminotransferase
EC 2.6.1.79 glutamate—prephenate aminotransferase
EC 2.6.1.80 nicotianamine aminotransferase
EC 2.6.1.81 succinylornithine transaminase
EC 2.6.1.82 putrescine aminotransferase
EC 2.6.1.83 LL-diaminopimelate aminotransferase
EC 2.6.1.84 arginine—pyruvate transaminase
EC 2.6.1.85 aminodeoxychorismate synthase
EC 2.6.1.86 2-amino-4-deoxychorismate synthase
EC 2.6.2 Amidinotransferases
EC 2.6.2.1 now EC 2.1.4.1
EC 2.6.3 Oximinotransaminases
EC 2.6.3.1 oximinotransferase
EC 2.6.99 Transferring Other Nitrogenous Groups
EC 2.6.99.1 dATP(dGTP)—DNA purinetransferase
EC 2.6.99.2 pyridoxine 5'-phosphate synthase
EC 2.7 Transferring phosphorus-containing groups
EC 2.7.1 Phosphotransferases with an alcohol group as acceptor
EC 2.7.1.1 hexokinase
EC 2.7.1.2 glucokinase
EC 2.7.1.3 ketohexokinase
EC 2.7.1.4 fructokinase
EC 2.7.1.5 rhamnulokinase
EC 2.7.1.6 galactokinase
EC 2.7.1.7 mannokinase
EC 2.7.1.8 glucosamine kinase
EC 2.7.1.9 deleted
EC 2.7.1.10 phosphoglucokinase
EC 2.7.1.11 6-phosphofructokinase
EC 2.7.1.12 gluconokinase
EC 2.7.1.13 dehydrogluconokinase
EC 2.7.1.14 sedoheptulokinase
EC 2.7.1.15 ribokinase
EC 2.7.1.16 ribulokinase
EC 2.7.1.17 xylulokinase
EC 2.7.1.18 phosphoribokinase
EC 2.7.1.19 phosphoribulokinase
EC 2.7.1.20 adenosine kinase
EC 2.7.1.21 thymidine kinase
EC 2.7.1.22 ribosylnicotinamide kinase
EC 2.7.1.23 NAD+ kinase
EC 2.7.1.24 dephospho-CoA kinase
EC 2.7.1.25 adenylyl-sulfate kinase
EC 2.7.1.26 riboflavin kinase
EC 2.7.1.27 erythritol kinase
EC 2.7.1.28 triokinase
EC 2.7.1.29 glycerone kinase
EC 2.7.1.30 glycerol kinase
EC 2.7.1.31 glycerate kinase
EC 2.7.1.32 choline kinase
EC 2.7.1.33 pantothenate kinase
EC 2.7.1.34 pantetheine kinase
EC 2.7.1.35 pyridoxal kinase
EC 2.7.1.36 mevalonate kinase
EC 2.7.1.37 now divided into EC 2.7.11.1, EC 2.7.11.8, EC 2.7.11.9, EC 2.7.11.10,
EC 2.7.11.11, EC 2.7.11.12, EC 2.7.11.13, EC 2.7.11.21, EC 2.7.11.22, EC
2.7.11.24, EC 2.7.11.25, EC 2.7.11.30 and EC 2.7.12.1
EC 2.7.1.38 now EC 2.7.11.19
EC 2.7.1.39 homoserine kinase
EC 2.7.1.40 pyruvate kinase
EC 2.7.1.41 glucose-1-phosphate phosphodismutase
EC 2.7.1.42 riboflavin phosphotransferase
EC 2.7.1.43 glucuronokinase
EC 2.7.1.44 galacturonokinase
EC 2.7.1.45 2-dehydro-3-deoxygluconokinase
EC 2.7.1.46 L-arabinokinase
EC 2.7.1.47 D-ribulokinase
EC 2.7.1.48 uridine kinase
EC 2.7.1.49 hydroxymethylpyrimidine kinase
EC 2.7.1.50 hydroxyethylthiazole kinase
EC 2.7.1.51 L-fuculokinase
EC 2.7.1.52 fucokinase
EC 2.7.1.53 L-xylulokinase
EC 2.7.1.54 D-arabinokinase
EC 2.7.1.55 allose kinase
EC 2.7.1.56 1-phosphofructokinase
EC 2.7.1.57 deleted
EC 2.7.1.58 2-dehydro-3-deoxygalactonokinase
EC 2.7.1.59 N-acetylglucosamine kinase
EC 2.7.1.60 N-acylmannosamine kinase
EC 2.7.1.61 acyl-phosphate—hexose phosphotransferase
EC 2.7.1.62 phosphoramidate—hexose phosphotransferase
EC 2.7.1.63 polyphosphate—glucose phosphotransferase
EC 2.7.1.64 inositol 3-kinase
EC 2.7.1.65 scyllo-inosamine 4-kinase
EC 2.7.1.66 undecaprenol kinase
EC 2.7.1.67 1-phosphatidylinositol 4-kinase
EC 2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase
EC 2.7.1.69 protein-Nπ-phosphohistidine—sugar phosphotransferase
EC 2.7.1.70 identical to EC 2.7.1.37.
EC 2.7.1.71 shikimate kinase
EC 2.7.1.72 streptomycin 6-kinase
EC 2.7.1.73 inosine kinase
EC 2.7.1.74 deoxycytidine kinase
EC 2.7.1.75 now EC 2.7.1.21
EC 2.7.1.76 deoxyadenosine kinase
EC 2.7.1.77 nucleoside phosphotransferase
EC 2.7.1.78 polynucleotide 5'-hydroxyl-kinase
EC 2.7.1.79 diphosphate—glycerol phosphotransferase
EC 2.7.1.80 diphosphate—serine phosphotransferase
EC 2.7.1.81 hydroxylysine kinase
EC 2.7.1.82 ethanolamine kinase
EC 2.7.1.83 pseudouridine kinase
EC 2.7.1.84 alkylglycerone kinase
EC 2.7.1.85 β-glucoside kinase
EC 2.7.1.86 NADH kinase
EC 2.7.1.87 streptomycin 3"-kinase
EC 2.7.1.88 dihydrostreptomycin-6-phosphate 3'α-kinase
EC 2.7.1.89 thiamine kinase
EC 2.7.1.90 diphosphate—fructose-6-phosphate 1-phosphotransferase
EC 2.7.1.91 sphinganine kinase
EC 2.7.1.92 5-dehydro-2-deoxygluconokinase
EC 2.7.1.93 alkylglycerol kinase
EC 2.7.1.94 acylglycerol kinase
EC 2.7.1.95 kanamycin kinase
EC 2.7.1.96 deleted, included in EC 2.7.1.86
EC 2.7.1.97 deleted, identical to EC 2.7.1.125
EC 2.7.1.98 deleted
EC 2.7.1.99 now EC 2.7.11.2
EC 2.7.1.100 S-methyl-5-thioribose kinase
EC 2.7.1.101 tagatose kinase
EC 2.7.1.102 hamamelose kinase
EC 2.7.1.103 viomycin kinase
EC 2.7.1.104 now EC 2.7.99.1
EC 2.7.1.105 6-phosphofructo-2-kinase
EC 2.7.1.106 glucose-1,6-bisphosphate synthase
EC 2.7.1.107 diacylglycerol kinase
EC 2.7.1.108 dolichol kinase
EC 2.7.1.109 now EC 2.7.11.31
EC 2.7.1.110 now EC 2.7.11.3
EC 2.7.1.111 now EC 2.7.1.128
EC 2.7.1.112 now EC 2.7.10.1 and EC 2.7.10.2
EC 2.7.1.113 deoxyguanosine kinase
EC 2.7.1.114 AMP—thymidine kinase
EC 2.7.1.115 now EC 2.7.11.4
EC 2.7.1.116 now EC 2.7.11.5
EC 2.7.1.117 now EC 2.7.11.18
EC 2.7.1.118 ADP—thymidine kinase
EC 2.7.1.119 hygromycin-B 7"-O-kinase
EC 2.7.1.120 now part of EC 2.7.11.17
EC 2.7.1.121 phosphoenolpyruvate—glycerone phosphotransferase
EC 2.7.1.122 xylitol kinase
EC 2.7.1.123 now part of EC 2.7.11.17
EC 2.7.1.124 now EC 2.7.11.6
EC 2.7.1.125 now EC 2.7.11.14
EC 2.7.1.126 now EC 2.7.11.15
EC 2.7.1.127 inositol-trisphosphate 3-kinase
EC 2.7.1.128 now EC 2.7.11.27
EC 2.7.1.129 now EC 2.7.11.7
EC 2.7.1.130 tetraacyldisaccharide 4'-kinase
EC 2.7.1.131 now EC 2.7.11.29
EC 2.7.1.132 now EC 2.7.11.28
EC 2.7.1.133 now with EC 2.7.1.134
EC 2.7.1.134 inositol-tetrakisphosphate 1-kinase
EC 2.7.1.135 now EC 2.7.11.26
EC 2.7.1.136 macrolide 2'-kinase
EC 2.7.1.137 phosphatidylinositol 3-kinase
EC 2.7.1.138 ceramide kinase
EC 2.7.1.139 now with EC 2.7.1.134
EC 2.7.1.140 inositol-tetrakisphosphate 5-kinase
EC 2.7.1.141 now EC 2.7.11.23
EC 2.7.1.142 glycerol—3-phosphate-glucose phosphotransferase
EC 2.7.1.143 diphosphate-purine nucleoside kinase
EC 2.7.1.144 tagatose-6-phosphate kinase
EC 2.7.1.145 deoxynucleoside kinase
EC 2.7.1.146 ADP-dependent phosphofructokinase
EC 2.7.1.147 ADP-dependent glucokinase
EC 2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
EC 2.7.1.149 1-phosphatidylinositol-5-phosphate 4-kinase
EC 2.7.1.150 1-phosphatidylinositol-3-phosphate 5-kinase
EC 2.7.1.151 inositol-polyphosphate multikinase
EC 2.7.1.152 now EC 2.7.4.21
EC 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase
EC 2.7.1.154 phosphatidylinositol-4-phosphate 3-kinase
EC 2.7.1.155 now EC 2.7.4.24
EC 2.7.1.156 adenosylcobinamide kinase
EC 2.7.1.157 N-acetylgalactosamine kinase
EC 2.7.1.158 inositol-pentakisphosphate 2-kinase
EC 2.7.1.159 inositol-1,3,4-trisphosphate 5/6-kinase
EC 2.7.1.160 2'-phosphotransferase
EC 2.7.1.161 CTP-dependent riboflavin kinase
EC 2.7.1.162 N-acetylhexosamine 1-kinase
EC 2.7.1.163 hygromycin B 4-O-kinase
EC 2.7.1.164 O-phosphoseryl-tRNASec kinase
EC 2.7.2 Phosphotransferases with a carboxy group as acceptor
EC 2.7.2.1 acetate kinase
EC 2.7.2.2 carbamate kinase
EC 2.7.2.3 phosphoglycerate kinase
EC 2.7.2.4 aspartate kinase
EC 2.7.2.5 now EC 6.3.4.16
EC 2.7.2.6 formate kinase
EC 2.7.2.7 butyrate kinase
EC 2.7.2.8 acetylglutamate kinase
EC 2.7.2.9 now EC 6.3.5.5
EC 2.7.2.10 phosphoglycerate kinase (GTP)
EC 2.7.2.11 glutamate 5-kinase
EC 2.7.2.12 acetate kinase (diphosphate)
EC 2.7.2.13 glutamate 1-kinase
EC 2.7.2.14 branched-chain-fatty-acid kinase
EC 2.7.2.15 propionate kinase
EC 2.7.3 Phosphotransferases with a nitrogenous group as acceptor
EC 2.7.3.1 guanidinoacetate kinase
EC 2.7.3.2 creatine kinase
EC 2.7.3.3 arginine kinase
EC 2.7.3.4 taurocyamine kinase
EC 2.7.3.5 lombricine kinase
EC 2.7.3.6 hypotaurocyamine kinase
EC 2.7.3.7 opheline kinase
EC 2.7.3.8 ammonia kinase
EC 2.7.3.9 phosphoenolpyruvate—protein phosphotransferase
EC 2.7.3.10 agmatine kinase
EC 2.7.3.11 now EC 2.7.13.1
EC 2.7.3.12 now EC 2.7.13.2
EC 2.7.4 Phosphotransferases with a phosphate group as acceptor
EC 2.7.4.1 polyphosphate kinase
EC 2.7.4.2 phosphomevalonate kinase
EC 2.7.4.3 adenylate kinase
EC 2.7.4.4 nucleoside-phosphate kinase
EC 2.7.4.5 deleted, included in EC 2.7.4.14
EC 2.7.4.6 nucleoside-diphosphate kinase
EC 2.7.4.7 phosphomethylpyrimidine kinase
EC 2.7.4.8 guanylate kinase
EC 2.7.4.9 dTMP kinase
EC 2.7.4.10 nucleoside-triphosphate—adenylate kinase
EC 2.7.4.11 (deoxy)adenylate kinase
EC 2.7.4.12 T2-induced deoxynucleotide kinase
EC 2.7.4.13 (deoxy)nucleoside-phosphate kinase
EC 2.7.4.14 cytidylate kinase
EC 2.7.4.15 thiamine-diphosphate kinase
EC 2.7.4.16 thiamine-phosphate kinase
EC 2.7.4.17 3-phosphoglyceroyl-phosphate—polyphosphate phosphotransferase
EC 2.7.4.18 farnesyl-diphosphate kinase
EC 2.7.4.19 5-methyldeoxycytidine-5'-phosphate kinase
EC 2.7.4.20 dolichyl-diphosphate—polyphosphate phosphotransferase
EC 2.7.4.21 inositol-hexakisphosphate kinase
EC 2.7.4.22 UMP kinase
EC 2.7.4.23 ribose 1,5-bisphosphate phosphokinase
EC 2.7.4.24 diphosphoinositol-pentakisphosphate kinase
EC 2.7.5 Phosphotransferases with regeneration of donors, apparently catalysing
intramolecular transfers
EC 2.7.5.1 now EC 5.4.2.2
EC 2.7.5.2 now EC 5.4.2.3
EC 2.7.5.3 now EC 5.4.2.1
EC 2.7.5.4 now EC 5.4.2.4
EC 2.7.5.5 now EC 5.4.2.5
EC 2.7.5.6 now EC 5.4.2.7
EC 2.7.5.7 now EC 5.4.2.8
EC 2.7.6 Diphosphotransferases
EC 2.7.6.1 ribose-phosphate diphosphokinase
EC 2.7.6.2 thiamine diphosphokinase
EC 2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
EC 2.7.6.4 nucleotide diphosphokinase
EC 2.7.6.5 GTP diphosphokinase
EC 2.7.7 Nucleotidyltransferases
EC 2.7.7.1 nicotinamide-nucleotide adenylyltransferase
EC 2.7.7.2 FAD synthetase
EC 2.7.7.3 pantetheine-phosphate adenylyltransferase
EC 2.7.7.4 sulfate adenylyltransferase
EC 2.7.7.5 sulfate adenylyltransferase (ADP)
EC 2.7.7.6 DNA-directed RNA polymerase
EC 2.7.7.7 DNA-directed DNA polymerase
EC 2.7.7.8 polyribonucleotide nucleotidyltransferase
EC 2.7.7.9 UTP—glucose-1-phosphate uridylyltransferase
EC 2.7.7.10 UTP—hexose-1-phosphate uridylyltransferase
EC 2.7.7.11 UTP—xylose-1-phosphate uridylyltransferase
EC 2.7.7.12 UDP-glucose—hexose-1-phosphate uridylyltransferase
EC 2.7.7.13 mannose-1-phosphate guanylyltransferase
EC 2.7.7.14 ethanolamine-phosphate cytidylyltransferase
EC 2.7.7.15 choline-phosphate cytidylyltransferase
EC 2.7.7.16 now EC 3.1.27.5
EC 2.7.7.17 now EC 3.1.27.1
EC 2.7.7.18 nicotinate-nucleotide adenylyltransferase
EC 2.7.7.19 polynucleotide adenylyltransferase
EC 2.7.7.20 deleted
EC 2.7.7.21 tRNA cytidylyltransferase
EC 2.7.7.22 mannose-1-phosphate guanylyltransferase (GDP)
EC 2.7.7.23 UDP-N-acetylglucosamine diphosphorylase
EC 2.7.7.24 glucose-1-phosphate thymidylyltransferase
EC 2.7.7.25 tRNA adenylyltransferase
EC 2.7.7.26 now EC 3.1.27.3
EC 2.7.7.27 glucose-1-phosphate adenylyltransferase
EC 2.7.7.28 nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase
EC 2.7.7.29 identical to EC 2.7.7.28
EC 2.7.7.30 fucose-1-phosphate guanylyltransferase
EC 2.7.7.31 DNA nucleotidylexotransferase
EC 2.7.7.32 galactose-1-phosphate thymidylyltransferase
EC 2.7.7.33 glucose-1-phosphate cytidylyltransferase
EC 2.7.7.34 glucose-1-phosphate guanylyltransferase
EC 2.7.7.35 ribose-5-phosphate adenylyltransferase
EC 2.7.7.36 aldose-1-phosphate adenylyltransferase
EC 2.7.7.37 aldose-1-phosphate nucleotidyltransferase
EC 2.7.7.38 3-deoxy-manno-octulosonate cytidylyltransferase
EC 2.7.7.39 glycerol-3-phosphate cytidylyltransferase
EC 2.7.7.40 D-ribitol-5-phosphate cytidylyltransferase
EC 2.7.7.41 phosphatidate cytidylyltransferase
EC 2.7.7.42 [glutamate—ammonia-ligase] adenylyltransferase
EC 2.7.7.43 N-acylneuraminate cytidylyltransferase
EC 2.7.7.44 glucuronate-1-phosphate uridylyltransferase
EC 2.7.7.45 guanosine-triphosphate guanylyltransferase
EC 2.7.7.46 gentamicin 2"-nucleotidyltransferase
EC 2.7.7.47 streptomycin 3"-adenylyltransferase
EC 2.7.7.48 RNA-directed RNA polymerase
EC 2.7.7.49 RNA-directed DNA polymerase
EC 2.7.7.50 mRNA guanylyltransferase
EC 2.7.7.51 adenylyl-sulfate—ammonia adenylyltransferase
EC 2.7.7.52 RNA uridylyltransferase
EC 2.7.7.53 ATP adenylyltransferase
EC 2.7.7.54 phenylalanine adenylyltransferase
EC 2.7.7.55 anthranilate adenylyltransferase
EC 2.7.7.56 tRNA nucleotidyltransferase
EC 2.7.7.57 N-methylphosphoethanolamine cytidylyltransferase
EC 2.7.7.58 (2,3-dihydroxybenzoyl)adenylate synthase
EC 2.7.7.59 [protein-PII] uridylyltransferase
EC 2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
EC 2.7.7.61 citrate lyase holo-[acyl-carrier protein] synthase
EC 2.7.7.62 adenosylcobinamide-phosphate guanylyltransferase
EC 2.7.7.63 lipoate—protein ligase
EC 2.7.7.64 UTP-monosaccharide-1-phosphate uridylyltransferase
EC 2.7.7.65 diguanylate cyclase
EC 2.7.7.66 malonate decarboxylase holo-[acyl-carrier protein] synthase
EC 2.7.7.67 CDP-archaeol synthase
EC 2.7.7.68 2-phospho-L-lactate guanylyltransferase
EC 2.7.8 Transferases for other substituted phosphate groups
EC 2.7.8.1 ethanolaminephosphotransferase
EC 2.7.8.2 diacylglycerol cholinephosphotransferase
EC 2.7.8.3 ceramide cholinephosphotransferase
EC 2.7.8.4 serine-phosphoethanolamine synthase
EC 2.7.8.5 CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase
EC 2.7.8.6 undecaprenyl-phosphate galactose phosphotransferase
EC 2.7.8.7 holo-[acyl-carrier-protein] synthase
EC 2.7.8.8 CDP-diacylglycerol—serine O-phosphatidyltransferase
EC 2.7.8.9 phosphomannan mannosephosphotransferase
EC 2.7.8.10 sphingosine cholinephosphotransferase
EC 2.7.8.11 CDP-diacylglycerol—inositol 3-phosphatidyltransferase
EC 2.7.8.12 CDP-glycerol glycerophosphotransferase
EC 2.7.8.13 phospho-N-acetylmuramoyl-pentapeptide-transferase
EC 2.7.8.14 CDP-ribitol ribitolphosphotransferase
EC 2.7.8.15 UDP-N-acetylglucosamine—dolichyl-phosphate N-
acetylglucosaminephosphotransferase
EC 2.7.8.16 deleted, included in EC 2.7.8.2
EC 2.7.8.17 UDP-N-acetylglucosamine—lysosomal-enzyme N-
acetylglucosaminephosphotransferase
EC 2.7.8.18 UDP-galactose—UDP-N-acetylglucosamine galactose
phosphotransferase
EC 2.7.8.19 UDP-glucose—glycoprotein glucose phosphotransferase
EC 2.7.8.20 phosphatidylglycerol—membrane-oligosaccharide
glycerophosphotransferase
EC 2.7.8.21 membrane-oligosaccharide glycerophosphotransferase
EC 2.7.8.22 1-alkenyl-2-acylglycerol choline phosphotransferase
EC 2.7.8.23 carboxyvinyl-carboxyphosphonate phosphorylmutase
EC 2.7.8.24 phosphatidylcholine synthase
EC 2.7.8.25 triphosphoribosyl-dephospho-CoA synthase
EC 2.7.8.26 adenosylcobinamide-GDP ribazoletransferase
EC 2.7.8.27 sphingomyelin synthase
EC 2.7.8.28 2-phospho-L-lactate transferase
EC 2.7.9 Phosphotransferases with paired acceptors
EC 2.7.9.1 pyruvate, phosphate dikinase
EC 2.7.9.2 pyruvate, water dikinase
EC 2.7.9.3 selenide, water dikinase
EC 2.7.9.4 α-glucan, water dikinase
EC 2.7.9.5 phosphoglucan, water dikinase
EC 2.7.10 Protein-tyrosine kinases
EC 2.7.10.1 receptor protein-tyrosine kinase
EC 2.7.10.2 non-specific protein-tyrosine kinase
EC 2.7.11 Protein-serine/threonine kinases
EC 2.7.11.1 non-specific serine/threonine protein kinase
EC 2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase
EC 2.7.11.3 dephospho-[reductase kinase] kinase
EC 2.7.11.4 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase
EC 2.7.11.5 [isocitrate dehydrogenase (NADP+)] kinase
EC 2.7.11.6 [tyrosine 3-monooxygenase] kinase
EC 2.7.11.7 myosin-heavy-chain kinase
EC 2.7.11.8 Fas-activated serine/threonine kinase
EC 2.7.11.9 Goodpasture-antigen-binding protein kinase
EC 2.7.11.10 IκB kinase
EC 2.7.11.11 cAMP-dependent protein kinase
EC 2.7.11.12 cGMP-dependent protein kinase
EC 2.7.11.13 protein kinase C
EC 2.7.11.14 rhodopsin kinase
EC 2.7.11.15 β-adrenergic-receptor kinase
EC 2.7.11.16 G-protein-coupled receptor kinase
EC 2.7.11.17 Ca2+/calmodulin-dependent protein kinase
EC 2.7.11.18 myosin-light-chain kinase
EC 2.7.11.19 phosphorylase kinase
EC 2.7.11.20 elongation factor 2 kinase
EC 2.7.11.21 polo kinase
EC 2.7.11.22 cyclin-dependent kinase
EC 2.7.11.23 [RNA-polymerase]-subunit kinase
EC 2.7.11.24 mitogen-activated protein kinase
EC 2.7.11.25 mitogen-activated protein kinase kinase kinase
EC 2.7.11.26 tau-protein kinase
EC 2.7.11.27 [acetyl-CoA carboxylase] kinase
EC 2.7.11.28 tropomyosin kinase
EC 2.7.11.29 low-density-lipoprotein receptor kinase
EC 2.7.11.30 receptor protein serine/threonine kinase
EC 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
EC 2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
EC 2.7.12.1 dual-specificity kinase
EC 2.7.12.2 mitogen-activated protein kinase kinase
EC 2.7.13 Protein-histidine kinases
EC 2.7.13.1 protein-histidine pros-kinase
EC 2.7.13.2 protein-histidine tele-kinase
EC 2.7.13.3 histidine kinase
EC 2.7.99 Other protein kinases
EC 2.7.99.1 triphosphate—protein phosphotransferase
EC 2.8 Transferring sulfur-containing groups
EC 2.8.1 Sulfurtransferases
EC 2.8.1.1 thiosulfate sulfurtransferase
EC 2.8.1.2 3-mercaptopyruvate sulfurtransferase
EC 2.8.1.3 thiosulfate—thiol sulfurtransferase
EC 2.8.1.4 tRNA sulfurtransferase
EC 2.8.1.5 thiosulfate—dithiol sulfurtransferase
EC 2.8.1.6 biotin synthase
EC 2.8.1.7 cysteine desulfurase
EC 2.8.1.8 lipoyl synthase
EC 2.8.2 Sulfotransferases
EC 2.8.2.1 aryl sulfotransferase
EC 2.8.2.2 alcohol sulfotransferase
EC 2.8.2.3 amine sulfotransferase
EC 2.8.2.4 estrone sulfotransferase
EC 2.8.2.5 chondroitin 4-sulfotransferase
EC 2.8.2.6 choline sulfotransferase
EC 2.8.2.7 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase
EC 2.8.2.8 desulfoheparin sulfotransferase
EC 2.8.2.9 tyrosine-ester sulfotransferase
EC 2.8.2.10 Renilla-luciferin sulfotransferase
EC 2.8.2.11 galactosylceramide sulfotransferase
EC 2.8.2.12 deleted, identical to EC 2.8.2.8
EC 2.8.2.13 psychosine sulfotransferase
EC 2.8.2.14 bile-salt sulfotransferase
EC 2.8.2.15 steroid sulfotransferase
EC 2.8.2.16 thiol sulfotransferase
EC 2.8.2.17 chondroitin 6-sulfotransferase
EC 2.8.2.18 cortisol sulfotransferase
EC 2.8.2.19 triglucosylalkylacylglycerol sulfotransferase
EC 2.8.2.20 protein-tyrosine sulfotransferase
EC 2.8.2.21 keratan sulfotransferase
EC 2.8.2.22 aryl-sulfate sulfotransferase
EC 2.8.2.23 [heparan sulfate]-glucosamine 3-sulfotransferase 1
EC 2.8.2.24 desulfoglucosinolate sulfotransferase
EC 2.8.2.25 flavonol 3-sulfotransferase
EC 2.8.2.26 quercetin-3-sulfate 3'-sulfotransferase
EC 2.8.2.27 quercetin-3-sulfate 4'-sulfotransferase
EC 2.8.2.28 quercetin-3,3'-bissulfate 7-sulfotransferase
EC 2.8.2.29 [heparan sulfate]-glucosamine 3-sulfotransferase 2
EC 2.8.2.30 [heparan sulfate]-glucosamine 3-sulfotransferase 3
EC 2.8.2.31 petromyzonol sulfotransferase
EC 2.8.2.32 scymnol sulfotransferase
EC 2.8.2.33 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase
EC 2.8.2.34 glycochenodeoxycholate sulfotransferase
EC 2.8.3 CoA-transferases
EC 2.8.3.1 propionate CoA-transferase
EC 2.8.3.2 oxalate CoA-transferase
EC 2.8.3.3 malonate CoA-transferase
EC 2.8.3.4 deleted
EC 2.8.3.5 3-oxoacid CoA-transferase
EC 2.8.3.6 3-oxoadipate CoA-transferase
EC 2.8.3.7 succinate—citramalate CoA-transferase
EC 2.8.3.8 acetate CoA-transferase
EC 2.8.3.9 butyrate—acetoacetate CoA-transferase
EC 2.8.3.10 citrate CoA-transferase
EC 2.8.3.11 citramalate CoA-transferase
EC 2.8.3.12 glutaconate CoA-transferase
EC 2.8.3.13 succinate—hydroxymethylglutarate CoA-transferase
EC 2.8.3.14 5-hydroxypentanoate CoA-transferase
EC 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase
EC 2.8.3.16 formyl-CoA transferase
EC 2.8.3.17 cinnamoyl-CoA:phenyllactate CoA-transferase
EC 2.8.4 Transferring alkylthio groups
EC 2.8.4.1 coenzyme-B sulfoethylthiotransferase
EC 2.9 Transferring selenium-containing groups
EC 2.9.1 Selenotransferases
EC 2.9.1.1 L-seryl-tRNASec selenium transferase
EC 2.9.1.2 O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase

EC 3 Hydrolases
Enzim-enzim yang mengkatalisi hidrolisis ikatan-ikatn ester, eter, peptida, glikosil, anhidrida
asam, C-C, C-halida, atau P-N.
EC 3.1 Acting on ester bonds
EC 3.1.1 Carboxylic Ester Hydrolases
EC 3.1.1.1 carboxylesterase
EC 3.1.1.2 arylesterase
EC 3.1.1.3 triacylglycerol lipase
EC 3.1.1.4 phospholipase A2
EC 3.1.1.5 lysophospholipase
EC 3.1.1.6 acetylesterase
EC 3.1.1.7 acetylcholinesterase
EC 3.1.1.8 cholinesterase
EC 3.1.1.9 deleted
EC 3.1.1.10 tropinesterase
EC 3.1.1.11 pectinesterase
EC 3.1.1.12 deleted
EC 3.1.1.13 sterol esterase
EC 3.1.1.14 chlorophyllase
EC 3.1.1.15 L-arabinonolactonase
EC 3.1.1.16 deleted, mixture of EC 5.3.3.4 and EC 3.1.1.24
EC 3.1.1.17 gluconolactonase
EC 3.1.1.18 deleted, included in EC 3.1.1.17
EC 3.1.1.19 uronolactonase
EC 3.1.1.20 tannase
EC 3.1.1.21 retinyl-palmitate esterase
EC 3.1.1.22 hydroxybutyrate-dimer hydrolase
EC 3.1.1.23 acylglycerol lipase
EC 3.1.1.24 3-oxoadipate enol-lactonase
EC 3.1.1.25 1,4-lactonase
EC 3.1.1.26 galactolipase
EC 3.1.1.27 4-pyridoxolactonase
EC 3.1.1.28 acylcarnitine hydrolase
EC 3.1.1.29 aminoacyl-tRNA hydrolase
EC 3.1.1.30 D-arabinonolactonase
EC 3.1.1.31 6-phosphogluconolactonase
EC 3.1.1.32 phospholipase A1
EC 3.1.1.33 6-acetylglucose deacetylase
EC 3.1.1.34 lipoprotein lipase
EC 3.1.1.35 dihydrocoumarin hydrolase
EC 3.1.1.36 limonin-D-ring-lactonase
EC 3.1.1.37 steroid-lactonase
EC 3.1.1.38 triacetate-lactonase
EC 3.1.1.39 actinomycin lactonase
EC 3.1.1.40 orsellinate-depside hydrolase
EC 3.1.1.41 cephalosporin-C deacetylase
EC 3.1.1.42 chlorogenate hydrolase
EC 3.1.1.43 α-amino-acid esterase
EC 3.1.1.44 4-methyloxaloacetate esterase
EC 3.1.1.45 carboxymethylenebutenolidase
EC 3.1.1.46 deoxylimonate A-ring-lactonase
EC 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase
EC 3.1.1.48 fusarinine-C ornithinesterase
EC 3.1.1.49 sinapine esterase
EC 3.1.1.50 wax-ester hydrolase
EC 3.1.1.51 phorbol-diester hydrolase
EC 3.1.1.52 phosphatidylinositol deacylase
EC 3.1.1.53 sialate O-acetylesterase
EC 3.1.1.54 acetoxybutynylbithiophene deacetylase
EC 3.1.1.55 acetylsalicylate deacetylase
EC 3.1.1.56 methylumbelliferyl-acetate deacetylase
EC 3.1.1.57 2-pyrone-4,6-dicarboxylate lactonase
EC 3.1.1.58 N-acetylgalactosaminoglycan deacetylase
EC 3.1.1.59 juvenile-hormone esterase
EC 3.1.1.60 bis(2-ethylhexyl)phthalate esterase
EC 3.1.1.61 protein-glutamate methylesterase
EC 3.1.1.62 now EC 3.5.1.47
EC 3.1.1.63 11-cis-retinyl-palmitate hydrolase
EC 3.1.1.64 all-trans-retinyl-palmitate hydrolase
EC 3.1.1.65 L-rhamnono-1,4-lactonase
EC 3.1.1.66 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase
EC 3.1.1.67 fatty-acyl-ethyl-ester synthase
EC 3.1.1.68 xylono-1,4-lactonase
EC 3.1.1.69 now EC 3.5.1.89
EC 3.1.1.70 cetraxate benzylesterase
EC 3.1.1.71 acetylalkylglycerol acetylhydrolase
EC 3.1.1.72 acetylxylan esterase
EC 3.1.1.73 feruloyl esterase
EC 3.1.1.74 cutinase
EC 3.1.1.75 poly(3-hydroxybutyrate) depolymerase
EC 3.1.1.76 poly(3-hydroxyoctanoate) depolymerase
EC 3.1.1.77 acyloxyacyl hydrolase
EC 3.1.1.78 polyneuridine-aldehyde esterase
EC 3.1.1.79 hormone-sensitive lipase
EC 3.1.1.80 acetylajmaline esterase
EC 3.1.1.81 quorum-quenching N-acyl-homoserine lactonase
EC 3.1.1.82 pheophorbidase
EC 3.1.1.83 monoterpene ε-lactone hydrolase

EC 3.1.2 Thioester Hydrolases


EC 3.1.2.1 acetyl-CoA hydrolase
EC 3.1.2.2 palmitoyl-CoA hydrolase
EC 3.1.2.3 succinyl-CoA hydrolase
EC 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase
EC 3.1.2.5 hydroxymethylglutaryl-CoA hydrolase
EC 3.1.2.6 hydroxyacylglutathione hydrolase
EC 3.1.2.7 glutathione thiolesterase
EC 3.1.2.8 deleted, included in EC 3.1.2.6
EC 3.1.2.9 deleted
EC 3.1.2.10 formyl-CoA hydrolase
EC 3.1.2.11 acetoacetyl-CoA hydrolase
EC 3.1.2.12 S-formylglutathione hydrolase
EC 3.1.2.13 S-succinylglutathione hydrolase
EC 3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase
EC 3.1.2.15 ubiquitin thiolesterase
EC 3.1.2.16 citrate lyase deacetylase
EC 3.1.2.17 (S)-methylmalonyl-CoA hydrolase
EC 3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase
EC 3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase
EC 3.1.2.20 acyl-CoA hydrolase
EC 3.1.2.21 dodecanoyl-[acyl-carrier protein] hydrolase
EC 3.1.2.22 palmitoyl[protein] hydrolase
EC 3.1.2.23 4-hydroxybenzoyl-CoA thioesterase
EC 3.1.2.24 now EC 3.13.1.3
EC 3.1.2.25 phenylacetyl-CoA hydrolase
EC 3.1.2.26 bile-acid-CoA hydrolase
EC 3.1.2.27 choloyl-CoA hydrolase
EC 3.1.3 Phosphoric Monoester Hydrolases
EC 3.1.3.1 alkaline phosphatase
EC 3.1.3.2 acid phosphatase
EC 3.1.3.3 phosphoserine phosphatase
EC 3.1.3.4 phosphatidate phosphatase
EC 3.1.3.5 5'-nucleotidase
EC 3.1.3.6 3'-nucleotidase
EC 3.1.3.7 3'(2'),5'-bisphosphate nucleotidase
EC 3.1.3.8 3-phytase
EC 3.1.3.9 glucose-6-phosphatase
EC 3.1.3.10 glucose-1-phosphatase
EC 3.1.3.11 fructose-bisphosphatase
EC 3.1.3.12 trehalose-phosphatase
EC 3.1.3.13 bisphosphoglycerate phosphatase
EC 3.1.3.14 methylphosphothioglycerate phosphatase
EC 3.1.3.15 histidinol-phosphatase
EC 3.1.3.16 phosphoprotein phosphatase
EC 3.1.3.17 [phosphorylase] phosphatase
EC 3.1.3.18 phosphoglycolate phosphatase
EC 3.1.3.19 glycerol-2-phosphatase
EC 3.1.3.20 phosphoglycerate phosphatase
EC 3.1.3.21 glycerol-1-phosphatase
EC 3.1.3.22 mannitol-1-phosphatase
EC 3.1.3.23 sugar-phosphatase
EC 3.1.3.24 sucrose-phosphate phosphatase
EC 3.1.3.25 inositol-phosphate phosphatase
EC 3.1.3.26 4-phytase
EC 3.1.3.27 phosphatidylglycerophosphatase
EC 3.1.3.28 ADPphosphoglycerate phosphatase
EC 3.1.3.29 N-acylneuraminate-9-phosphatase
EC 3.1.3.30 deleted, included in EC 3.1.3.31
EC 3.1.3.31 nucleotidase
EC 3.1.3.32 polynucleotide 3'-phosphatase
EC 3.1.3.33 polynucleotide 5'-phosphatase
EC 3.1.3.34 deoxynucleotide 3'-phosphatase
EC 3.1.3.35 thymidylate 5'-phosphatase
EC 3.1.3.36 phosphoinositide 5-phosphatase
EC 3.1.3.37 sedoheptulose-bisphosphatase
EC 3.1.3.38 3-phosphoglycerate phosphatase
EC 3.1.3.39 streptomycin-6-phosphatase
EC 3.1.3.40 guanidinodeoxy-scyllo-inositol-4-phosphatase
EC 3.1.3.41 4-nitrophenylphosphatase
EC 3.1.3.42 [glycogen-synthase-D] phosphatase
EC 3.1.3.43 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase
EC 3.1.3.44 [acetyl-CoA carboxylase]-phosphatase
EC 3.1.3.45 3-deoxy-manno-octulosonate-8-phosphatase
EC 3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase
EC 3.1.3.47 [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase
EC 3.1.3.48 protein-tyrosine-phosphatase
EC 3.1.3.49 [pyruvate kinase]-phosphatase
EC 3.1.3.50 sorbitol-6-phosphatase
EC 3.1.3.51 dolichyl-phosphatase
EC 3.1.3.52 [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase
EC 3.1.3.53 [myosin-light-chain] phosphatase
EC 3.1.3.54 fructose-2,6-bisphosphate 6-phosphatase
EC 3.1.3.55 caldesmon-phosphatase
EC 3.1.3.56 inositol-polyphosphate 5-phosphatase
EC 3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase
EC 3.1.3.58 sugar-terminal-phosphatase
EC 3.1.3.59 alkylacetylglycerophosphatase
EC 3.1.3.60 phosphoenolpyruvate phosphatase
EC 3.1.3.61 deleted
EC 3.1.3.62 multiple inositol-polyphosphate phosphatase
EC 3.1.3.63 2-carboxy-D-arabinitol-1-phosphatase
EC 3.1.3.64 phosphatidylinositol-3-phosphatase
EC 3.1.3.65 now with EC 3.1.3.64
EC 3.1.3.66 phosphatidylinositol-3,4-bisphosphate 4-phosphatase
EC 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
EC 3.1.3.68 2-deoxyglucose-6-phosphatase
EC 3.1.3.69 glucosylglycerol 3-phosphatase
EC 3.1.3.70 mannosyl-3-phosphoglycerate phosphatase
EC 3.1.3.71 2-phosphosulfolactate phosphatase
EC 3.1.3.72 5-phytase
EC 3.1.3.73 α-ribazole phosphatase
EC 3.1.3.74 pyridoxal phosphatase
EC 3.1.3.75 phosphoethanolamine/phosphocholine phosphatase
EC 3.1.3.76 lipid-phosphate phosphatase
EC 3.1.3.77 acireductone synthase
EC 3.1.3.78 phosphatidylinositol-4,5-bisphosphate 4-phosphatase
EC 3.1.3.79 mannosylfructose-phosphate phosphatase
EC 3.1.3.80 2,3-bisphosphoglycerate 3-phosphatase
EC 3.1.4 Phosphoric Diester Hydrolases
EC 3.1.4.1 phosphodiesterase I
EC 3.1.4.2 glycerophosphocholine phosphodiesterase
EC 3.1.4.3 phospholipase C
EC 3.1.4.4 phospholipase D
EC 3.1.4.5 now EC 3.1.21.1
EC 3.1.4.6 now EC 3.1.22.1
EC 3.1.4.7 now EC 3.1.31.1
EC 3.1.4.8 now EC 3.1.27.3
EC 3.1.4.9 now EC 3.1.30.2
EC 3.1.4.10 now EC 4.6.1.13
EC 3.1.4.11 phosphoinositide phospholipase C
EC 3.1.4.12 sphingomyelin phosphodiesterase
EC 3.1.4.13 serine-ethanolaminephosphate phosphodiesterase
EC 3.1.4.14 [acyl-carrier-protein] phosphodiesterase
EC 3.1.4.15 adenylyl-[glutamate—ammonia ligase] hydrolase
EC 3.1.4.16 2',3'-cyclic-nucleotide 2'-phosphodiesterase
EC 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
EC 3.1.4.18 now EC 3.1.16.1
EC 3.1.4.19 now EC 3.1.13.3
EC 3.1.4.20 now EC 3.1.13.1
EC 3.1.4.21 now EC 3.1.30.1
EC 3.1.4.22 now EC 3.1.27.5
EC 3.1.4.23 now EC 3.1.27.1
EC 3.1.4.24 deleted
EC 3.1.4.25 now EC 3.1.11.1
EC 3.1.4.26 deleted
EC 3.1.4.27 now EC 3.1.11.2
EC 3.1.4.28 now EC 3.1.11.3
EC 3.1.4.29 deleted
EC 3.1.4.30 now EC 3.1.21.2
EC 3.1.4.31 now EC 3.1.11.4
EC 3.1.4.32 deleted
EC 3.1.4.33 deleted
EC 3.1.4.34 deleted
EC 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
EC 3.1.4.36 now with EC 3.1.4.43
EC 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase
EC 3.1.4.38 glycerophosphocholine cholinephosphodiesterase
EC 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase
EC 3.1.4.40 CMP-N-acylneuraminate phosphodiesterase
EC 3.1.4.41 sphingomyelin phosphodiesterase D
EC 3.1.4.42 glycerol-1,2-cyclic-phosphate 2-phosphodiesterase
EC 3.1.4.43 glycerophosphoinositol inositolphosphodiesterase
EC 3.1.4.44 glycerophosphoinositol glycerophosphodiesterase
EC 3.1.4.45 N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase
EC 3.1.4.46 glycerophosphodiester phosphodiesterase
EC 3.1.4.47 now EC 4.6.1.14
EC 3.1.4.48 dolichylphosphate-glucose phosphodiesterase
EC 3.1.4.49 dolichylphosphate-mannose phosphodiesterase
EC 3.1.4.50 glycosylphosphatidylinositol phospholipase D
EC 3.1.4.51 glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase
EC 3.1.4.52 cyclic-guanylate-specific phosphodiesterase
EC 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
EC 3.1.5 Triphosphoric Monoester Hydrolases
EC 3.1.5.1 dGTPase
EC 3.1.6 Sulfuric Ester Hydrolases
EC 3.1.6.1 arylsulfatase
EC 3.1.6.2 steryl-sulfatase
EC 3.1.6.3 glycosulfatase
EC 3.1.6.4 N-acetylgalactosamine-6-sulfatase
EC 3.1.6.5 deleted
EC 3.1.6.6 choline-sulfatase
EC 3.1.6.7 cellulose-polysulfatase
EC 3.1.6.8 cerebroside-sulfatase
EC 3.1.6.9 chondro-4-sulfatase
EC 3.1.6.10 chondro-6-sulfatase
EC 3.1.6.11 disulfoglucosamine-6-sulfatase
EC 3.1.6.12 N-acetylgalactosamine-4-sulfatase
EC 3.1.6.13 iduronate-2-sulfatase
EC 3.1.6.14 N-acetylglucosamine-6-sulfatase
EC 3.1.6.15 N-sulfoglucosamine-3-sulfatase
EC 3.1.6.16 monomethyl-sulfatase
EC 3.1.6.17 D-lactate-2-sulfatase
EC 3.1.6.18 glucuronate-2-sulfatase
EC 3.1.7 Diphosphoric Monoester Hydrolases
EC 3.1.7.1 prenyl-diphosphatase
EC 3.1.7.2 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
EC 3.1.7.3 monoterpenyl-diphosphatase
EC 3.1.7.4 sclareol cyclase
EC 3.1.7.5 geranylgeranyl diphosphate diphosphatase
EC 3.1.8 Phosphoric Triester Hydrolases
EC 3.1.8.1 aryldialkylphosphatase
EC 3.1.8.2 diisopropyl-fluorophosphatase
EC 3.1.11 Exodeoxyribonucleases Producing 5'-Phosphomonoesters
EC 3.1.11.1 exodeoxyribonuclease I
EC 3.1.11.2 exodeoxyribonuclease III
EC 3.1.11.3 exodeoxyribonuclease (lambda-induced)
EC 3.1.11.4 exodeoxyribonuclease (phage SP3-induced)
EC 3.1.11.5 exodeoxyribonuclease V
EC 3.1.11.6 exodeoxyribonuclease VII
EC 3.1.13 Exoribonucleases Producing 5'-Phosphomonoesters
EC 3.1.13.1 exoribonuclease II
EC 3.1.13.2 exoribonuclease H
EC 3.1.13.3 oligonucleotidase
EC 3.1.13.4 poly(A)-specific ribonuclease
EC 3.1.13.5 ribonuclease D
EC 3.1.14 Exoribonucleases Producing 3'-Phosphomonoesters
EC 3.1.14.1 yeast ribonuclease
EC 3.1.15 Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing
5'-Phosphomonoesters
EC 3.1.15.1 venom exonuclease
EC 3.1.16 Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing
3'-Phosphomonoesters
EC 3.1.16.1 spleen exonuclease
EC 3.1.21 Endodeoxyribonucleases Producing 5'-Phosphomonoesters
EC 3.1.21.1 deoxyribonuclease I
EC 3.1.21.2 deoxyribonuclease IV (phage-T4-induced)
EC 3.1.21.3 type I site-specific deoxyribonuclease
EC 3.1.21.4 type II site-specific deoxyribonuclease
EC 3.1.21.5 type III site-specific deoxyribonuclease
EC 3.1.21.6 CC-preferring endodeoxyribonuclease
EC 3.1.21.7 deoxyribonuclease V
EC 3.1.22 Endodeoxyribonucleases Producing 3'-Phosphomonoesters
EC 3.1.22.1 deoxyribonuclease II
EC 3.1.22.2 Aspergillus deoxyribonuclease K1
EC 3.1.22.3 now EC 3.1.21.7
EC 3.1.22.4 crossover junction endodeoxyribonuclease
EC 3.1.22.5 deoxyribonuclease X
EC 3.1.23 Site Specific Endodeoxyribonucleases: Cleavage is Sequence Specific
(discontinued)
EC 3.1.24 Site Specific Endodeoxyribonucleases: Cleavage is not Sequence Specific
(discontinued)
EC 3.1.25 Site-Specific Endodeoxyribonucleases Specific for Altered Bases
EC 3.1.25.1 deoxyribonuclease (pyrimidine dimer)
EC 3.1.25.2 now EC 4.2.99.18
EC 3.1.26 Endoribonucleases Producing 5'-Phosphomonoesters
EC 3.1.26.1 Physarum polycephalum ribonuclease
EC 3.1.26.2 ribonculease alpha
EC 3.1.26.3 ribonuclease III
EC 3.1.26.4 calf thymus ribonuclease H
EC 3.1.26.5 ribonuclease P
EC 3.1.26.6 ribonuclease IV
EC 3.1.26.7 ribonuclease P4
EC 3.1.26.8 ribonuclease M5
EC 3.1.26.9 ribonuclease [poly-(U)-specific]
EC 3.1.26.10 ribonuclease IX
EC 3.1.26.11 tRNase Z
EC 3.1.26.12 ribonuclease E
EC 3.1.26.13 retroviral ribonuclease H
EC 3.1.27 Endoribonucleases Producing 3'-Phosphomonoesters
EC 3.1.27.1 ribonuclease T2
EC 3.1.27.2 Bacillus subtilis ribonuclease
EC 3.1.27.3 ribonuclease T1
EC 3.1.27.4 riblonuclease U2
EC 3.1.27.5 pancreatic ribonuclease
EC 3.1.27.6 Enterobacter ribonuclease
EC 3.1.27.7 ribonuclease F
EC 3.1.27.8 ribonuclease V
EC 3.1.27.9 tRNA-intron endonuclease
EC 3.1.27.10 rRNA endonuclease
EC 3.1.30 Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and
Producing 5'-Phosphomonoesters
EC 3.1.30.1 Aspergillus nuclease S1
EC 3.1.30.2 Serratia marcescens nuclease
EC 3.1.31 Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and
Producing 3'-Phosphomonoesters
EC 3.1.31.1 micrococcal nuclease
EC 3.2 Glycosylases
EC 3.2.1 Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
EC 3.2.1.1 α-amylase
EC 3.2.1.2 β-amylase
EC 3.2.1.3 glucan 1,4-α-glucosidase
EC 3.2.1.4 cellulase
EC 3.2.1.5 deleted
EC 3.2.1.6 endo-1,3(4)-β-glucanase
EC 3.2.1.7 inulinase
EC 3.2.1.8 endo-1,4-β-xylanase
EC 3.2.1.9 deleted
EC 3.2.1.10 oligo-1,6-glucosidase
EC 3.2.1.11 dextranase
EC 3.2.1.12 deleted, included in EC 3.2.1.54
EC 3.2.1.13 deleted, included in EC 3.2.1.54
EC 3.2.1.14 chitinase
EC 3.2.1.15 polygalacturonase
EC 3.2.1.16 deleted
EC 3.2.1.17 lysozyme
EC 3.2.1.18 exo-α-sialidase
EC 3.2.1.19 deleted
EC 3.2.1.20 α-glucosidase
EC 3.2.1.21 β-glucosidase
EC 3.2.1.22 α-galactosidase
EC 3.2.1.23 β-galactosidase
EC 3.2.1.24 α-mannosidase
EC 3.2.1.25 β-mannosidase
EC 3.2.1.26 β-fructofuranosidase
EC 3.2.1.27 deleted
EC 3.2.1.28 α,α-trehalase
EC 3.2.1.29 deleted, included in EC 3.2.1.52
EC 3.2.1.30 deleted, included in EC 3.2.1.52
EC 3.2.1.31 β-glucuronidase
EC 3.2.1.32 xylan endo-1,3-β-xylosidase
EC 3.2.1.33 amylo-1,6-glucosidase
EC 3.2.1.34 deleted, included in EC 3.2.1.35
EC 3.2.1.35 hyaluronoglucosaminidase
EC 3.2.1.36 hyaluronoglucuronidase
EC 3.2.1.37 xylan 1,4-β-xylosidase
EC 3.2.1.38 β-D-fucosidase
EC 3.2.1.39 glucan endo-1,3-β-D-glucosidase
EC 3.2.1.40 α-L-rhamnosidase
EC 3.2.1.41 pullulanase
EC 3.2.1.42 GDP-glucosidase
EC 3.2.1.43 β-L-rhamnosidase
EC 3.2.1.44 fucoidanase
EC 3.2.1.45 glucosylceramidase
EC 3.2.1.46 galactosylceramidase
EC 3.2.1.47 galactosylgalactosylglucosylceramidase
EC 3.2.1.48 sucrose α-glucosidase
EC 3.2.1.49 α-N-acetylgalactosaminidase
EC 3.2.1.50 α-N-acetylglucosaminidase
EC 3.2.1.51 α-L-fucosidase
EC 3.2.1.52 β-L-N-acetylhexosaminidase
EC 3.2.1.53 β-N-acetylgalactosaminidase
EC 3.2.1.54 cyclomaltodextrinase
EC 3.2.1.55 α-N-arabinofuranosidase
EC 3.2.1.56 glucuronosyl-disulfoglucosamine glucuronidase
EC 3.2.1.57 isopullulanase
EC 3.2.1.58 glucan 1,3-β-glucosidase
EC 3.2.1.59 glucan endo-1,3-α-glucosidase
EC 3.2.1.60 glucan 1,4-α-maltotetraohydrolase
EC 3.2.1.61 mycodextranase
EC 3.2.1.62 glycosylceramidase
EC 3.2.1.63 1,2-α-L-fucosidase
EC 3.2.1.64 2,6-β-fructan 6-levanbiohydrolase
EC 3.2.1.65 levanase
EC 3.2.1.66 quercitrinase
EC 3.2.1.67 galacturan 1,4-α-galacturonidase
EC 3.2.1.68 isoamylase
EC 3.2.1.69 deleted, included in EC 3.2.1.41
EC 3.2.1.70 glucan 1,6-α-glucosidase
EC 3.2.1.71 glucan endo-1,2-β-glucosidase
EC 3.2.1.72 xylan 1,3-β-xylosidase
EC 3.2.1.73 licheninase
EC 3.2.1.74 glucan 1,4-β-glucosidase
EC 3.2.1.75 glucan endo-1,6-β-glucosidase
EC 3.2.1.76 L-iduronidase
EC 3.2.1.77 mannan 1,2-(1,3)-α-mannosidase
EC 3.2.1.78 mannan endo-1,4-β-mannosidase
EC 3.2.1.79 deleted, included in EC 3.2.1.55
EC 3.2.1.80 fructan β-fructosidase
EC 3.2.1.81 β-agarase
EC 3.2.1.82 exo-poly-α-galacturonosidase
EC 3.2.1.83 κ-carrageenase
EC 3.2.1.84 glucan 1,3-α-glucosidase
EC 3.2.1.85 6-phospho-β-galactosidase
EC 3.2.1.86 6-phospho-β-glucosidase
EC 3.2.1.87 capsular-polysaccharide endo-1,3-α-galactosidase
EC 3.2.1.88 β-L-arabinosidase
EC 3.2.1.89 arabinogalactan endo-1,4-β-galactosidase
EC 3.2.1.90 deleted, not sufficiently characterised.
EC 3.2.1.91 cellulose 1,4-β-cellobiosidase
EC 3.2.1.92 peptidoglycan β-N-acetylmuramidase
EC 3.2.1.93 α,α-phosphotrehalase
EC 3.2.1.94 glucan 1,6-α-isomaltosidase
EC 3.2.1.95 dextran 1,6-α-isomaltotriosidase
EC 3.2.1.96 mannosyl-glycoprotein endo-β-N-acetylglucosaminidase
EC 3.2.1.97 glycopeptide α-N-acetylgalactosaminidase
EC 3.2.1.98 glucan 1,4-α-maltohexaosidase
EC 3.2.1.99 arabinan endo-1,5-α-L-arabinosidase
EC 3.2.1.100 mannan 1,4-mannobiosidase
EC 3.2.1.101 mannan endo-1,6-α-mannosidase
EC 3.2.1.102 blood-group-substance endo-1,4-β-galactosidase
EC 3.2.1.103 keratan-sulfate endo-1,4-β-galactosidase
EC 3.2.1.104 steryl-β-glucosidase
EC 3.2.1.105 strictosidine β-glucosidase
EC 3.2.1.106 mannosyl-oligosaccharide glucosidase
EC 3.2.1.107 protein-glucosylgalactosylhydroxylysine glucosidase
EC 3.2.1.108 lactase
EC 3.2.1.109 endogalactosaminidase
EC 3.2.1.110 deleted identical to EC 3.2.1.97
EC 3.2.1.111 1,3-α-L-fucosidase
EC 3.2.1.112 2-deoxyglucosidase
EC 3.2.1.113 mannosyl-oligosaccharide 1,2-α-mannosidase
EC 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-α-mannosidase
EC 3.2.1.115 branched-dextran exo-1,2-α-glucosidase
EC 3.2.1.116 glucan 1,4-α-maltotriohydrolase
EC 3.2.1.117 amygdalin β-glucosidase
EC 3.2.1.118 prunasin β-glucosidase
EC 3.2.1.119 vicianin β-glucosidase
EC 3.2.1.120 oligoxyloglucan β-glycosidase
EC 3.2.1.121 polymannuronate hydrolase
EC 3.2.1.122 maltose-6'-phosphate glucosidase
EC 3.2.1.123 endoglycosylceramidase
EC 3.2.1.124 3-deoxy-2-octulosonidase
EC 3.2.1.125 raucaffricine β-glucosidase
EC 3.2.1.126 coniferin β-glucosidase
EC 3.2.1.127 1,6-α-L-fucosidase
EC 3.2.1.128 glycyrrhizinate β-glucuronidase
EC 3.2.1.129 endo-α-sialidase
EC 3.2.1.130 glycoprotein endo-α-1,2-mannosidase
EC 3.2.1.131 xylan α-1,2-glucuronosidase
EC 3.2.1.132 chitosanase
EC 3.2.1.133 glucan 1,4-α-maltohydrolase
EC 3.2.1.134 difructose-anhydride synthase
EC 3.2.1.135 neopullulanase
EC 3.2.1.136 glucuronoarabinoxylan endo-1,4-β-xylanase
EC 3.2.1.137 mannan exo-1,2-1,6-α-mannosidase
EC 3.2.1.138 now EC 4.2.2.15
EC 3.2.1.139 α-glucuronidase
EC 3.2.1.140 lacto-N-biosidase
EC 3.2.1.141 4-α-D-{(1 4)-α-D-glucano}trehalose trehalohydrolase
EC 3.2.1.142 limit dextrinase
EC 3.2.1.143 poly(ADP-ribose) glycohydrolase
EC 3.2.1.144 3-deoxyoctulosonase
EC 3.2.1.145 galactan 1,3-β-galactosidase
EC 3.2.1.146 β-galactofuranosidase
EC 3.2.1.147 thioglucosidase
EC 3.2.1.148 now EC 4.4.1.21
EC 3.2.1.149 β-primeverosidase
EC 3.2.1.150 oligoxyloglucan reducing-end-specific cellobiohydrolase
EC 3.2.1.151 xyloglucan-specific endo-β-1,4-glucanase
EC 3.2.1.152 mannosylglycoprotein endo-β-mannosidase
EC 3.2.1.153 fructan β-(2,1)-fructosidase
EC 3.2.1.154 fructan β-(2,6)-fructosidase
EC 3.2.1.155 xyloglucan-specific exo-β-1,4-glucanase
EC 3.2.1.156 oligosaccharide reducing-end xylanase
EC 3.2.1.157 ι-carrageenase
EC 3.2.1.158 α-agarase
EC 3.2.1.159 α-neoagaro-oligosaccharide hydrolase
EC 3.2.1.160 deleted, identical to EC 3.2.1.155
EC 3.2.1.161 β-apiosyl-β-glucosidase
EC 3.2.1.162 λ-carrageenase
EC 3.2.1.163 1,6-α-D-mannosidase
EC 3.2.1.164 galactan endo-1,6-β-galactosidase
EC 3.2.1.165 exo-1,4-β-D-glucosaminidase
EC 3.2.2 Hydrolysing N-Glycosyl Compounds
EC 3.2.2.1 purine nucleosidase
EC 3.2.2.2 inosine nucleosidase
EC 3.2.2.3 uridine nucleosidase
EC 3.2.2.4 AMP nucleosidase
EC 3.2.2.5 NAD+ nucleosidase
EC 3.2.2.6 NAD(P)+ nucleosidase
EC 3.2.2.7 adenosine nucleosidase
EC 3.2.2.8 ribosylpyrimidine nucleosidase
EC 3.2.2.9 adenosylhomocysteine nucleosidase
EC 3.2.2.10 pyrimidine-5'-nucleotide nucleosidase
EC 3.2.2.11 β-aspartyl-N-acetylglucosaminidase
EC 3.2.2.12 inosinate nucleosidase
EC 3.2.2.13 1-methyladenosine nucleosidase
EC 3.2.2.14 NMN nucleosidase
EC 3.2.2.15 DNA-deoxyinosine glycosylase
EC 3.2.2.16 methylthioadenosine nucleosidase
EC 3.2.2.17 deoxyribodipyrimidine endonucleosidase
EC 3.2.2.18 deleted, included in EC 3.5.1.52
EC 3.2.2.19 ADP-ribosylarginine hydrolase
EC 3.2.2.20 DNA-3-methyladenine glycosylase I
EC 3.2.2.21 DNA-3-methyladenine glycosylase II
EC 3.2.2.22 rRNA N-glycosylase
EC 3.2.2.23 DNA-formamidopyrimidine glycosylase
EC 3.2.2.24 ADP-ribosyl-[dinitrogen reductase] hydrolase
EC 3.2.2.25 N-methyl nucleosidase
EC 3.2.2.26 futalosine hydrolase
EC 3.2.2.27 uracil-DNA glycosylase
EC 3.2.2.28 double-stranded uracil-DNA glycosylase
EC 3.2.2.29 thymine-DNA glycosylase
EC 3.2.3 Hydrolysing S-Glycosyl Compounds (discontinued)
EC 3.3 Acting on ether bonds
EC 3.3.1 Thioether and trialkylsulfonium hydrolases
EC 3.3.1.1 adenosylhomocysteinase
EC 3.3.1.2 adenosylmethionine hydrolase
EC 3.3.1.3 now EC 3.2.1.148 ribosylhomocysteinase
EC 3.3.2 Ether hydrolases
EC 3.3.2.1 isochorismatase
EC 3.3.2.2 alkenylglycerophosphocholine hydrolase
EC 3.3.2.3 now
EC 3.3.2.4 trans-epoxysuccinate hydrolase
EC 3.3.2.5 alkenylglycerophosphoethanolamine hydrolase
EC 3.3.2.6 leukotriene-A4 hydrolase
EC 3.3.2.7 hepoxilin-epoxide hydrolase
EC 3.3.2.8 limonene-1,2-epoxide hydrolase
EC 3.3.2.9 microsomal epoxide hydrolase
EC 3.3.2.10 soluble epoxide hydrolase
EC 3.3.2.11 cholesterol-5,6-oxide hydrolase
EC 3.4 Acting on peptide bonds (peptidases)
EC 3.4.1 a-Amino-Acyl-Peptide Hydrolases (now in EC 3.4.11)
EC 3.4.2 Peptidyl-Amino-Acid Hydrolases (now in EC 3.4.17)
EC 3.4.3 Dipeptide Hydrolases (now in EC 3.4.13)
EC 3.4.4 Peptidyl Peptide Hydrolases (now reclassified within EC 3.4)
EC 3.4.11 Aminopeptidases
EC 3.4.11.1 leucyl aminopeptidase
EC 3.4.11.2 membrane alanyl aminopeptidase
EC 3.4.11.3 cystinyl aminopeptidase
EC 3.4.11.4 tripeptide aminopeptidase
EC 3.4.11.5 prolyl aminopeptidase
EC 3.4.11.6 arginyl aminopeptidase
EC 3.4.11.7 glutamyl aminopeptidase
EC 3.4.11.8 now EC 3.4.19.3
EC 3.4.11.9 Xaa-Pro aminopeptidase
EC 3.4.11.10 bacterial leucyl aminopeptidase
EC 3.4.11.11 deleted
EC 3.4.11.12 deleted (Supplement 4)
EC 3.4.11.13 clostridial aminopeptidase
EC 3.4.11.14 cytosol alanyl aminopeptidase
EC 3.4.11.15 lysyl aminopeptidase
EC 3.4.11.16 Xaa-Trp aminopeptidase
EC 3.4.11.17 tryptophanyl aminopeptidase
EC 3.4.11.18 methionyl aminopeptidase
EC 3.4.11.19 D-stereospecific aminopeptidase
EC 3.4.11.20 aminopeptidase Ey
EC 3.4.11.21 aspartyl aminopeptidase
EC 3.4.11.22 aminopeptidase I
EC 3.4.11.23 PepB aminopeptidase
EC 3.4.11.24 aminopeptidase S
EC 3.4.12 Peptidylamino-Acid Hydrolases or Acylamino-Acid Hydrolases (now reclassified
within EC 3.4)
EC 3.4.13 Dipeptidases
EC 3.4.13.1 now EC 3.4.13.18
EC 3.4.13.2 now EC 3.4.13.18
EC 3.4.13.3 Xaa-His dipeptidase
EC 3.4.13.4 Xaa-Arg dipeptidase
EC 3.4.13.5 Xaa-methyl-His dipeptidase
EC 3.4.13.6 now EC 3.4.11.2 (Supplement 4)
EC 3.4.13.7 Glu-Glu dipeptidase
EC 3.4.13.8 now EC 3.4.17.21 (Supplement 6)
EC 3.4.13.9 Xaa-Pro dipeptidase
EC 3.4.13.10 now EC 3.4.19.5
EC 3.4.13.11 deleted, included in EC 3.4.13.18
EC 3.4.13.12 Met-Xaa dipeptidase
EC 3.4.13.13 deleted, included in EC 3.4.13.3
EC 3.4.13.14 deleted
EC 3.4.13.15 deleted, included in EC 3.4.13.18
EC 3.4.13.16 deleted
EC 3.4.13.17 non-stereospecific dipeptidase
EC 3.4.13.18 cytosol nonspecific dipeptidase
EC 3.4.13.19 membrane dipeptidase
EC 3.4.13.20 β-Ala-His dipeptidase
EC 3.4.13.21 dipeptidase E
EC 3.4.13.22 D-Ala-D-Ala dipeptidase
EC 3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases
EC 3.4.14.1 dipeptidyl-peptidase I
EC 3.4.14.2 dipeptidyl-peptidase II
EC 3.4.14.3 now EC 3.4.19.1
EC 3.4.14.4 dipeptidyl-peptidase III
EC 3.4.14.5 dipeptidyl-peptidase IV
EC 3.4.14.6 dipeptidyl-dipeptidase
EC 3.4.14.7 deleted
EC 3.4.14.8 now covered by EC 3.4.14.9, EC 3.4.14.9 tripeptidyl-peptidase I
EC 3.4.14.10 tripeptidyl-peptidase II
EC 3.4.14.11 Xaa-Pro dipeptidyl-peptidase
EC 3.4.14.12 prolyltripeptidyl aminopeptidase
EC 3.4.15 Peptidyl-dipeptidases
EC 3.4.15.1 peptidyl-dipeptidase A
EC 3.4.15.2 now EC 3.4.19.2
EC 3.4.15.3 deleted, included in EC 3.4.15.5 (supplement 2)
EC 3.4.15.4 peptidyl-dipeptidase B
EC 3.4.15.5 peptidyl-dipeptidase Dcp
EC 3.4.15.6 cyanophycinase
EC 3.4.16 Serine-type carboxypeptidases
EC 3.4.16.1 deleted, included in EC 3.4.16.5, EC 3.4.16.6 (supplement 1)
EC 3.4.16.2 lysosomal Pro-Xaa carboxypeptidase
EC 3.4.16.3 deleted, included in EC 3.4.16.5 (supplement 1)
EC 3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
EC 3.4.16.5 carboxypeptidase C
EC 3.4.16.6 carboxypeptidase D
EC 3.4.17 Metallocarboxypeptidases
EC 3.4.17.1 carboxypeptidase A
EC 3.4.17.2 carboxypeptidase B
EC 3.4.17.3 lysine carboxypeptidase
EC 3.4.17.4 Gly-Xaa carboxypeptidase
EC 3.4.17.5 deleted
EC 3.4.17.6 alanine carboxypeptidase
EC 3.4.17.7 now EC 3.4.19.10
EC 3.4.17.8 muramoylpentapeptide carboxypeptidase
EC 3.4.17.9 deleted, included in EC 3.4.17.4
EC 3.4.17.10 carboxypeptidase E
EC 3.4.17.11 glutamate carboxypeptidase
EC 3.4.17.12 carboxypeptidase M
EC 3.4.17.13 muramoyltetrapeptide carboxypeptidase
EC 3.4.17.14 zinc D-Ala-D-Ala carboxypeptidase
EC 3.4.17.15 carboxypeptidase A2
EC 3.4.17.16 membrane Pro-Xaa carboxypeptidase
EC 3.4.17.17 tubulinyl-Tyr carboxypeptidase
EC 3.4.17.18 carboxypeptidase T
EC 3.4.17.19 carboxypeptidase Taq
EC 3.4.17.20 carboxypeptidase U
EC 3.4.17.21 glutamate carboxypeptidase II
EC 3.4.17.22 metallocarboxypeptidase D
EC 3.4.17.23 angiotensin-converting enzyme 2
EC 3.4.18 Cysteine-type carboxypeptidases
EC 3.4.18.1 cathepsin X
EC 3.4.19 Omega peptidases
EC 3.4.19.1 acylaminoacyl-peptidase
EC 3.4.19.2 peptidyl-glycinamidase
EC 3.4.19.3 pyroglutamyl-peptidase I
EC 3.4.19.4 deleted
EC 3.4.19.5 β-aspartyl-peptidase
EC 3.4.19.6 pyroglutamyl-peptidase II
EC 3.4.19.7 N-formylmethionyl-peptidase
EC 3.4.19.8 now EC 3.4.17.21 (Supplement 6)
EC 3.4.19.9 γ-glutamyl hydrolase
EC 3.4.19.10 now EC 3.5.1.28 (Supplement 4)
EC 3.4.19.11 γ-D-glutamyl-meso-diaminopimelate peptidase I
EC 3.4.19.12 ubiquitinyl hydrolase 1
EC 3.4.21 Serine endopeptidases
EC 3.4.21.1 chymotrypsin
EC 3.4.21.2 chymotrypsin C
EC 3.4.21.3 metridin
EC 3.4.21.4 trypsin
EC 3.4.21.5 thrombin
EC 3.4.21.6 coagulation factor Xa
EC 3.4.21.7 plasmin
EC 3.4.21.8 now covered by EC 3.4.21.34 and EC 3.4.21.35
EC 3.4.21.9 enteropeptidase
EC 3.4.21.10 acrosin
EC 3.4.21.11 now covered by EC 3.4.21.36 and EC 3.4.21.37
EC 3.4.21.12 α-Lytic endopeptidase
EC 3.4.21.13 now EC 3.4.16.1
EC 3.4.21.14 now covered by EC 3.4.21.62 to EC 3.4.21.65 and EC 3.4.21.67
EC 3.4.21.15 now EC 3.4.21.63
EC 3.4.21.16 deleted
EC 3.4.21.17 deleted
EC 3.4.21.18 deleted
EC 3.4.21.19 glutamyl endopeptidase
EC 3.4.21.20 cathepsin G
EC 3.4.21.21 coagulation factor VIIa
EC 3.4.21.22 coagulation factor IXa
EC 3.4.21.23 deleted
EC 3.4.21.24 deleted
EC 3.4.21.25 cucumisin
EC 3.4.21.26 prolyl oligopeptidase
EC 3.4.21.27 coagulation factor XIa
EC 3.4.21.28 deleted, included in EC 3.4.21.74
EC 3.4.21.29 deleted, included in EC 3.4.21.74
EC 3.4.21.30 deleted, included in EC 3.4.21.74
EC 3.4.21.31 now covered by EC 3.4.21.68 and EC 3.4.21.73
EC 3.4.21.32 brachyurin
EC 3.4.21.33 deleted
EC 3.4.21.34 plasma kallikrein
EC 3.4.21.35 tissue kallikrein
EC 3.4.21.36 pancreatic elastase
EC 3.4.21.37 leukocyte elastase
EC 3.4.21.38 coagulation factor XIIa
EC 3.4.21.39 chymase
EC 3.4.21.40 deleted
EC 3.4.21.41 complement subcomponent C
EC 3.4.21.42 complement subcomponent C
EC 3.4.21.43 classical-complement-pathway C3/C5 convertase
EC 3.4.21.44 deleted, included in EC 3.4.21.43
EC 3.4.21.45 complement factor I
EC 3.4.21.46 complement factor D
EC 3.4.21.47 alternative-complement-pathway C3/C5 convertase
EC 3.4.21.48 cerevisin
EC 3.4.21.49 hypodermin C
EC 3.4.21.50 lysyl endopeptidase
EC 3.4.21.51 deleted
EC 3.4.21.52 deleted
EC 3.4.21.53 endopeptidase La
EC 3.4.21.54 γ-renin
EC 3.4.21.55 venombin AB
EC 3.4.21.56 deleted
EC 3.4.21.57 leucyl endopeptidase
EC 3.4.21.58 deleted
EC 3.4.21.59 tryptase
EC 3.4.21.60 scutelarin
EC 3.4.21.61 kexin
EC 3.4.21.62 subtilisin
EC 3.4.21.63 oryzin
EC 3.4.21.64 peptidase K
EC 3.4.21.65 thermomycolin
EC 3.4.21.66 thermitase
EC 3.4.21.67 endopeptidase So
EC 3.4.21.68 t-plasminogen activator
EC 3.4.21.69 protein C (activated)
EC 3.4.21.70 pancreatic endopeptidase E
EC 3.4.21.71 pancreatic elastase II
EC 3.4.21.72 IgA-specific serine endopeptidase
EC 3.4.21.73 u-plasminogen activator
EC 3.4.21.74 venombin A
EC 3.4.21.75 furin
EC 3.4.21.76 myeloblastin
EC 3.4.21.77 semenogelase
EC 3.4.21.78 granzyme A
EC 3.4.21.79 granzyme B
EC 3.4.21.80 streptogrisin A
EC 3.4.21.81 streptogrisin B
EC 3.4.21.82 glutamyl endopeptidase II
EC 3.4.21.83 oligopeptidase B

EC 3.4.21.84 limulus clotting factor

EC 3.4.21.85 limulus clotting factor


EC 3.4.21.86 limulus clotting enzyme
EC 3.4.21.87 now EC 3.4.23.49
EC 3.4.21.88 repressor LexA
EC 3.4.21.89 signal peptidase I
EC 3.4.21.90 togavirin
EC 3.4.21.91 flavivirin
EC 3.4.21.92 endopeptidase Clp
EC 3.4.21.93 proprotein convertase 1
EC 3.4.21.94 proprotein convertase 2
EC 3.4.21.95 snake venom factor V activator
EC 3.4.21.96 lactocepin
EC 3.4.21.97 assemblin
EC 3.4.21.98 hepacivirin
EC 3.4.21.99 spermosin
EC 3.4.21.100 sedolisin
EC 3.4.21.101 xanthomonalisin
EC 3.4.21.102 C-terminal processing peptidase
EC 3.4.21.103 physarolisin
EC 3.4.21.104 mannan-binding lectin-associated serine protease-2
EC 3.4.21.105 rhomboid protease
EC 3.4.21.106 hepsin
EC 3.4.21.107 peptidase Do
EC 3.4.21.108 HtrA2 peptidase
EC 3.4.21.109 matriptase
EC 3.4.21.110 C5a peptidase
EC 3.4.21.111 aqualysin 1
EC 3.4.21.112 site-1 protease
EC 3.4.21.113 pestivirus NS3 polyprotein peptidase
EC 3.4.21.114 equine arterivirus serine peptidase
EC 3.4.21.115 infectious pancreatic necrosis birnavirus Vp4 peptidase
EC 3.4.21.116 SpoIVB peptidase
EC 3.4.21.117 stratum corneum chymotryptic enzyme
EC 3.4.21.118 kallikrein 8
EC 3.4.21.119 kallikrein 13
EC 3.4.21.120 oviductin
EC 3.4.22 Cysteine endopeptidases
EC 3.4.22.1 cathepsin B
EC 3.4.22.2 papain
EC 3.4.22.3 ficain
EC 3.4.22.4 now covered by EC 3.4.22.32 and EC 3.4.22.33
EC 3.4.22.5 now EC 3.4.22.33
EC 3.4.22.6 chymopapain
EC 3.4.22.7 asclepain
EC 3.4.22.8 clostripain
EC 3.4.22.9 now EC 3.4.21.48
EC 3.4.22.10 streptopain
EC 3.4.22.11 now EC 3.4.24.56 (supplement 3)
EC 3.4.22.12 now EC 3.4.19.9
EC 3.4.22.13 deleted
EC 3.4.22.14 actinidain
EC 3.4.22.15 cathepsin L
EC 3.4.22.16 cathepsin H
EC 3.4.22.17 now EC 3.4.22.52 and EC 3.4.22.53
EC 3.4.22.18 deleted, included in EC 3.4.21.26
EC 3.4.22.19 deleted, included in EC 3.4.24.15
EC 3.4.22.20 deleted
EC 3.4.22.21 deleted, included in EC 3.4.99.46
EC 3.4.22.22 now EC 3.4.24.37
EC 3.4.22.23 deleted, included in EC 3.4.21.61
EC 3.4.22.24 cathepsin T
EC 3.4.22.25 glycyl endopeptidase
EC 3.4.22.26 cancer procoagulant
EC 3.4.22.27 cathepsin S
EC 3.4.22.28 picornain 3C
EC 3.4.22.29 picornain 2A
EC 3.4.22.30 caricain
EC 3.4.22.31 ananain
EC 3.4.22.32 stem bromelain
EC 3.4.22.33 fruit bromelain
EC 3.4.22.34 legumain
EC 3.4.22.35 histolysain
EC 3.4.22.36 caspase-1
EC 3.4.22.37 gingipain R
EC 3.4.22.38 cathepsin K
EC 3.4.22.39 adenain
EC 3.4.22.40 bleomycin hydrolase
EC 3.4.22.41 cathepsin F
EC 3.4.22.42 cathepsin O
EC 3.4.22.43 cathepsin V
EC 3.4.22.44 nuclear-inclusion-a endopeptidase
EC 3.4.22.45 helper-component proteinase
EC 3.4.22.46 L-peptidase
EC 3.4.22.47 gingipain K
EC 3.4.22.48 staphopain
EC 3.4.22.49 separase
EC 3.4.22.50 V-cath endopeptidase
EC 3.4.22.51 cruzipain
EC 3.4.22.52 calpain-1
EC 3.4.22.53 calpain-2
EC 3.4.22.54 calpain-3
EC 3.4.22.55 caspase-2
EC 3.4.22.56 caspase-3
EC 3.4.22.57 caspase-4
EC 3.4.22.58 caspase-5
EC 3.4.22.59 caspase-6
EC 3.4.22.60 caspase-7
EC 3.4.22.61 caspase-8
EC 3.4.22.62 caspase-9
EC 3.4.22.63 caspase-10
EC 3.4.22.64 caspase-11
EC 3.4.22.65 peptidase 1 (mite)
EC 3.4.22.66 calicivirin
EC 3.4.22.67 zingipain
EC 3.4.22.68 Ulp1 peptidase
EC 3.4.22.69 SARS coronavirus main proteinase
EC 3.4.22.70 sortase A
EC 3.4.22.71 sortase B
EC 3.4.23 Aspartic endopeptidases
EC 3.4.23.1 pepsin A
EC 3.4.23.2 pepsin B
EC 3.4.23.3 gastricsin
EC 3.4.23.4 chymosin
EC 3.4.23.5 cathepsin D
EC 3.4.23.6 now covered by EC 3.4.23.18 to EC 3.4.23.28 and EC 3.4.23.30
EC 3.4.23.7 now EC 3.4.24.20
EC 3.4.23.8 now EC 3.4.24.25
EC 3.4.23.9 now EC 3.4.24.21
EC 3.4.23.10 now EC 3.4.24.22
EC 3.4.23.11 deleted
EC 3.4.23.12 nepenthesin
EC 3.4.23.13 deleted
EC 3.4.23.14 deleted
EC 3.4.23.15 renin
EC 3.4.23.16 HIV-1 retropepsin
EC 3.4.23.17 Pro-opiomelanocortin converting enzyme
EC 3.4.23.18 aspergillopepsin I
EC 3.4.23.19 aspergillopepsin II
EC 3.4.23.20 penicillopepsin
EC 3.4.23.21 rhizopuspepsin
EC 3.4.23.22 endothiapepsin
EC 3.4.23.23 mucorpepsin
EC 3.4.23.24 candidapepsin
EC 3.4.23.25 saccharopepsin
EC 3.4.23.26 rhodotorulapepsin
EC 3.4.23.27 now EC 3.4.21.103
EC 3.4.23.28 acrocylindropepsin
EC 3.4.23.29 polyporopepsin
EC 3.4.23.30 pycnoporopepsin
EC 3.4.23.31 scytalidopepsin A
EC 3.4.23.32 scytalidopepsin B
EC 3.4.23.33 now EC 3.4.21.101
EC 3.4.23.34 cathepsin E
EC 3.4.23.35 barrierpepsin
EC 3.4.23.36 signal peptidase II
EC 3.4.23.37 now EC 3.4.21.100,
EC 3.4.23.38 plasmepsin I
EC 3.4.23.39 plasmepsin II
EC 3.4.23.40 phytepsin
EC 3.4.23.41 yapsin 1
EC 3.4.23.42 thermopsin
EC 3.4.23.43 prepilin peptidase
EC 3.4.23.44 nodavirus endopeptidase
EC 3.4.23.45 memapsin 1
EC 3.4.23.46 memapsin 2
EC 3.4.23.47 HIV-2 retropepsin
EC 3.4.23.48 plasminogen activator Pla
EC 3.4.23.49 omptin
EC 3.4.23.50 human endogenous retrovirus K endopeptidase
EC 3.4.23.51 HycI peptidase
EC 3.4.24 Metalloendopeptidases
EC 3.4.24.1 atrolysin A
EC 3.4.24.2 deleted
EC 3.4.24.3 microbial collagenase
EC 3.4.24.4 now covered by EC 3.4.24.25 to EC 3.4.24.32, EC 3.4.24.39 and EC
3.4.24.40
EC 3.4.24.5 now covered by EC 3.4.22.17 and EC 3.4.25.1
EC 3.4.24.6 leucolysin
EC 3.4.24.7 interstitial collagenase
EC 3.4.24.8 deleted, included in EC 3.4.24.3
EC 3.4.24.9 deleted
EC 3.4.24.10 deleted
EC 3.4.24.11 neprilysin
EC 3.4.24.12 envelysin
EC 3.4.24.13 IgA-specific metalloendopeptidase
EC 3.4.24.14 procollagen N-endopeptidase
EC 3.4.24.15 thimet oligopeptidase
EC 3.4.24.16 neurolysin
EC 3.4.24.17 stromelysin 1
EC 3.4.24.18 meprin A
EC 3.4.24.19 procollagen C-endopeptidase
EC 3.4.24.20 peptidyl-Lys metalloendopeptidase
EC 3.4.24.21 astacin
EC 3.4.24.22 stromelysin 2
EC 3.4.24.23 matrilysin
EC 3.4.24.24 gelatinase A
EC 3.4.24.25 vibriolysin
EC 3.4.24.26 pseudolysin
EC 3.4.24.27 thermolysin
EC 3.4.24.28 bacillolysin
EC 3.4.24.29 aureolysin
EC 3.4.24.30 coccolysin
EC 3.4.24.31 mycolysin
EC 3.4.24.32 β-lytic metalloendopeptidase
EC 3.4.24.33 peptidyl-Asp metalloendopeptidase
EC 3.4.24.34 neutrophil collagenase
EC 3.4.24.35 gelatinase B
EC 3.4.24.36 leishmanolysin
EC 3.4.24.37 saccharolysin
EC 3.4.24.38 gametolysin
EC 3.4.24.39 deuterolysin
EC 3.4.24.40 serralysin
EC 3.4.24.41 atrolysin B
EC 3.4.24.42 atrolysin C
EC 3.4.24.43 atroxase
EC 3.4.24.44 atrolysin E
EC 3.4.24.45 atrolysin F
EC 3.4.24.46 adamalysin
EC 3.4.24.47 horrilysin
EC 3.4.24.48 ruberlysin
EC 3.4.24.49 bothropasin
EC 3.4.24.50 bothrolysin
EC 3.4.24.51 ophiolysin
EC 3.4.24.52 trimerelysin I
EC 3.4.24.53 trimerelysin II
EC 3.4.24.54 mucrolysin
EC 3.4.24.55 pitrilysin
EC 3.4.24.56 insulysin
EC 3.4.24.57 O-sialoglycoprotein endopeptidase
EC 3.4.24.58 russellysin
EC 3.4.24.59 mitochondrial intermediate peptidase
EC 3.4.24.60 dactylysin
EC 3.4.24.61 nardilysin
EC 3.4.24.62 magnolysin
EC 3.4.24.63 meprin B
EC 3.4.24.64 mitochondrial processing peptidase
EC 3.4.24.65 macrophage elastase
EC 3.4.24.66 choriolysin L
EC 3.4.24.67 choriolysin H
EC 3.4.24.68 tentoxilysin
EC 3.4.24.69 bontoxilysin
EC 3.4.24.70 oligopeptidase A
EC 3.4.24.71 endothelin-converting enzyme
EC 3.4.24.72 fibrolase
EC 3.4.24.73 jararhagin
EC 3.4.24.74 fragilysin
EC 3.4.24.75 lysostaphin
EC 3.4.24.76 flavastacin
EC 3.4.24.77 snapalysin
EC 3.4.24.78 gpr endopeptidase
EC 3.4.24.79 pappalysin-1
EC 3.4.24.80 membrane-type matrix metalloproteinase-1
EC 3.4.24.81 ADAM10 endopeptidase
EC 3.4.24.82 ADAMTS-4 endopeptidase
EC 3.4.24.83 anthrax lethal factor endopeptidase
EC 3.4.24.84 Ste24 endopeptidase
EC 3.4.24.85 S2P endopeptidase
EC 3.4.24.86 ADAM 17 endopeptidase
EC 3.4.24.87 ADAMTS13 endopeptidase
EC 3.4.25 Threonine endopeptidases
EC 3.4.25.1 proteasome endopeptidase complex
EC 3.4.25.2 HslU—HslV peptidase
EC 3.4.99 Endopeptidases of unknown catalytic mechanism
EC 3.4.99.1 now EC 3.4.23.28
EC 3.4.99.2 deleted
EC 3.4.99.3 deleted
EC 3.4.99.4 now EC 3.4.23.12
EC 3.4.99.5 now EC 3.4.24.3
EC 3.4.99.6 now EC 3.4.24.21
EC 3.4.99.7 deleted
EC 3.4.99.8 deleted
EC 3.4.99.9 deleted
EC 3.4.99.10 now EC 3.4.24.56 (supplement 3)
EC 3.4.99.11 deleted
EC 3.4.99.12 deleted
EC 3.4.99.13 now EC 3.4.24.32
EC 3.4.99.14 deleted
EC 3.4.99.15 deleted
EC 3.4.99.16 deleted
EC 3.4.99.17 deleted
EC 3.4.99.18 deleted
EC 3.4.99.19 now EC 3.4.23.15
EC 3.4.99.20 deleted
EC 3.4.99.21 deleted
EC 3.4.99.22 now EC 3.4.24.29
EC 3.4.99.23 deleted
EC 3.4.99.24 deleted
EC 3.4.99.25 deleted, included in EC 3.4.23.21
EC 3.4.99.26 now covered by EC 3.4.24.73 and EC 3.4.21.68
EC 3.4.99.27 deleted
EC 3.4.99.28 now EC 3.4.21.60
EC 3.4.99.29 deleted
EC 3.4.99.30 deleted, included in EC 3.4.24.20
EC 3.4.99.31 deleted, included in EC 3.4.24.15
EC 3.4.99.32 now EC 3.4.24.20
EC 3.4.99.33 deleted
EC 3.4.99.34 deleted
EC 3.4.99.35 now EC 3.4.23.36 (supplement 2)
EC 3.4.99.36 now EC 3.4.21.89 (supplement 2)
EC 3.4.99.37 deleted
EC 3.4.99.38 now EC 3.4.23.17
EC 3.4.99.39 deleted
EC 3.4.99.40 deleted
EC 3.4.99.41 now EC 3.4.24.64 (supplement 2)
EC 3.4.99.42 deleted
EC 3.4.99.43 now EC 3.4.23.42 (supplement 6)
EC 3.4.99.44 now EC 3.4.24.55 (supplement 1)
EC 3.4.99.45 now EC 3.4.24.56 (supplement 1)
EC 3.4.99.46 now EC 3.4.25.1 (supplement 6)
EC 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
EC 3.5.1 In Linear Amides
EC 3.5.1.1 asparaginase
EC 3.5.1.2 glutaminase
EC 3.5.1.3 ω-amidase
EC 3.5.1.4 amidase
EC 3.5.1.5 urease
EC 3.5.1.6 β-ureidopropionase
EC 3.5.1.7 ureidosuccinase
EC 3.5.1.8 formylaspartate deformylase
EC 3.5.1.9 arylformamidase
EC 3.5.1.10 formyltetrahydrofolate deformylase
EC 3.5.1.11 penicillin amidase
EC 3.5.1.12 biotinidase
EC 3.5.1.13 aryl-acylamidase
EC 3.5.1.14 aminoacylase
EC 3.5.1.15 aspartoacylase
EC 3.5.1.16 acetylornithine deacetylase
EC 3.5.1.17 acyl-lysine deacylase
EC 3.5.1.18 succinyl-diaminopimelate desuccinylase
EC 3.5.1.19 nicotinamidase
EC 3.5.1.20 citrullinase
EC 3.5.1.21 N-acetyl-β-alanine deacetylase
EC 3.5.1.22 pantothenase
EC 3.5.1.23 ceramidase
EC 3.5.1.24 choloylglycine hydrolase
EC 3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase
EC 3.5.1.26 N4-(β-N-acetylglucosaminyl)-L-asparaginase
EC 3.5.1.27 N-formylmethionylaminoacyl-tRNA deformylase
EC 3.5.1.28 N-acetylmuramoyl-L-alanine amidase
EC 3.5.1.29 2-(acetamidomethylene)succinate hydrolase
EC 3.5.1.30 5-aminopentanamidase
EC 3.5.1.31 formylmethionine deformylase
EC 3.5.1.32 hippurate hydrolase
EC 3.5.1.33 N-acetylglucosamine deacetylase
EC 3.5.1.34 deleted, same as EC 3.4.13.5
EC 3.5.1.35 D-glutaminase
EC 3.5.1.36 N-methyl-2-oxoglutaramate hydrolase
EC 3.5.1.37 deleted, same as EC 3.5.1.26
EC 3.5.1.38 glutamin-(asparagin-)ase
EC 3.5.1.39 alkylamidase
EC 3.5.1.40 acylagmatine amidase
EC 3.5.1.41 chitin deacetylase
EC 3.5.1.42 nicotinamide-nucleotide amidase
EC 3.5.1.43 peptidyl-glutaminase
EC 3.5.1.44 protein-glutamine glutaminase
EC 3.5.1.45 now EC 6.3.4.6
EC 3.5.1.46 6-aminohexanoate-dimer hydrolase
EC 3.5.1.47 N-acetyldiaminopimelate deacetylase
EC 3.5.1.48 acetylspermidine deacetylase
EC 3.5.1.49 formamidase
EC 3.5.1.50 pentanamidase
EC 3.5.1.51 4-acetamidobutyryl-CoA deacetylase
EC 3.5.1.52 peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase
EC 3.5.1.53 N-carbamoylputrescine amidase
EC 3.5.1.54 allophanate hydrolase
EC 3.5.1.55 long-chain-fatty-acyl-glutamate deacylase
EC 3.5.1.56 N,N-dimethylformamidase
EC 3.5.1.57 tryptophanamidase
EC 3.5.1.58 N-benzyloxycarbonylglycine hydrolase
EC 3.5.1.59 N-carbamoylsarcosine amidase
EC 3.5.1.60 N-(long-chain-acyl)ethanolamine deacylase
EC 3.5.1.61 mimosinase
EC 3.5.1.62 acetylputrescine deacetylase
EC 3.5.1.63 4-acetamidobutyrate deacetylase
EC 3.5.1.64 Nα-benzyloxycarbonylleucine hydrolase
EC 3.5.1.65 theanine hydrolase
EC 3.5.1.66 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase
EC 3.5.1.67 4-methyleneglutaminase
EC 3.5.1.68 N-formylglutamate deformylase
EC 3.5.1.69 glycosphingolipid deacylase
EC 3.5.1.70 aculeacin-A deacylase
EC 3.5.1.71 N-feruloylglycine deacylase
EC 3.5.1.72 D-benzoylarginine-4-nitroanilide amidase
EC 3.5.1.73 carnitinamidase
EC 3.5.1.74 chenodeoxycholoyltaurine hydrolase
EC 3.5.1.75 urethanase
EC 3.5.1.76 arylalkyl acylamidase
EC 3.5.1.77 N-carbamoyl-D-amino acid hydrolase
EC 3.5.1.78 glutathionylspermidine amidase
EC 3.5.1.79 phthalyl amidase
EC 3.5.1.80 N-acetylgalactosamine-6-phosphate deacetylase
EC 3.5.1.81 N-acyl-D-amino-acid deacylase
EC 3.5.1.82 N-acyl-D-glutamate deacylase
EC 3.5.1.83 N-acyl-D-aspartate deacylase
EC 3.5.1.84 biuret amidohydrolase
EC 3.5.1.85 (S)-N-acetyl-1-phenylethylamine hydrolase
EC 3.5.1.86 mandelamide amidase
EC 3.5.1.87 N-carbamoyl-L-amino-acid hydrolase
EC 3.5.1.88 peptide deformylase
EC 3.5.1.89 N-acetylglucosaminylphosphatidylinositol deacetylase
EC 3.5.1.90 adenosylcobinamide hydrolase
EC 3.5.1.91 N-substituted formamide deformylase
EC 3.5.1.92 pantetheine hydrolase
EC 3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase
EC 3.5.1.94 γ-glutamyl-γ-aminobutyrate hydrolase
EC 3.5.1.95 N-malonylurea hydrolase
EC 3.5.1.96 succinylglutamate desuccinylase
EC 3.5.1.97 acyl-homoserine-lactone acylase
EC 3.5.1.98 histone deacetylase
EC 3.5.1.99 fatty acid amide hydrolase
EC 3.5.1.100 (R)-amidase
EC 3.5.1.101 L-proline amide hydrolase
EC 3.5.1.102 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-
monophosphate deformylase
EC 3.5.1.103 N-acetyl-1D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside
deacetylase
EC 3.5.2 In Cyclic Amides
EC 3.5.2.1 barbiturase
EC 3.5.2.2 dihydropyrimidinase
EC 3.5.2.3 dihydroorotase
EC 3.5.2.4 carboxymethylhydantoinase
EC 3.5.2.5 allantoinase
EC 3.5.2.6 β-lactamase
EC 3.5.2.7 imidazolonepropionase
EC 3.5.2.8 deleted, included in EC 3.5.2.6
EC 3.5.2.9 5-oxoprolinase (ATP-hydrolysing)
EC 3.5.2.10 creatininase
EC 3.5.2.11 L-lysine-lactamase
EC 3.5.2.12 6-aminohexanoate-cyclic-dimer hydrolase
EC 3.5.2.13 2,5-dioxopiperazine hydrolase
EC 3.5.2.14 N-methylhydantoinase (ATP-hydrolysing)
EC 3.5.2.15 cyanuric acid amidohydrolase
EC 3.5.2.16 maleimide hydrolase
EC 3.5.2.17 hydroxyisourate hydrolase
EC 3.5.2.18 enamidase
EC 3.5.3 In Linear Amidines
EC 3.5.3.1 arginase
EC 3.5.3.2 guanidinoacetase
EC 3.5.3.3 creatinase
EC 3.5.3.4 allantoicase
EC 3.5.3.5 formiminoaspartate deiminase
EC 3.5.3.6 arginine deiminase
EC 3.5.3.7 guanidinobutyrase
EC 3.5.3.8 formimidoylglutamase
EC 3.5.3.9 allantoate deiminase
EC 3.5.3.10 D-arginase
EC 3.5.3.11 agmatinase
EC 3.5.3.12 agmatine deiminase
EC 3.5.3.13 formiminoglutamate deiminase
EC 3.5.3.14 amidinoaspartase
EC 3.5.3.15 protein-arginine deiminase
EC 3.5.3.16 methylguanidinase
EC 3.5.3.17 guanidinopropionase
EC 3.5.3.18 dimethylargininase
EC 3.5.3.19 ureidoglycolate hydrolase
EC 3.5.3.20 diguanidinobutanase
EC 3.5.3.21 methylenediurea deaminase
EC 3.5.3.22 proclavaminate amidinohydrolase
EC 3.5.3.23 N-succinylarginine dihydrolase
EC 3.5.4 In Cyclic Amidines
EC 3.5.4.1 cytosine deaminase
EC 3.5.4.2 adenine deaminase
EC 3.5.4.3 guanine deaminase
EC 3.5.4.4 adenosine deaminase
EC 3.5.4.5 cytidine deaminase
EC 3.5.4.6 AMP deaminase
EC 3.5.4.7 ADP deaminase
EC 3.5.4.8 aminoimidazolase
EC 3.5.4.9 methenyltetrahydrofolate cyclohydrolase
EC 3.5.4.10 IMP cyclohydrolase
EC 3.5.4.11 pterin deaminase
EC 3.5.4.12 dCMP deaminase
EC 3.5.4.13 dCTP deaminase
EC 3.5.4.14 deoxycytidine deaminase
EC 3.5.4.15 guanosine deaminase
EC 3.5.4.16 GTP cyclohydrolase I
EC 3.5.4.17 adenosine-phosphate deaminase
EC 3.5.4.18 ATP deaminase
EC 3.5.4.19 phosphoribosyl-AMP cyclohydrolase
EC 3.5.4.20 pyrithiamine deaminase
EC 3.5.4.21 creatinine deaminase
EC 3.5.4.22 1-pyrroline-4-hydroxy-2-carboxylate deaminase
EC 3.5.4.23 blasticidin-S deaminase
EC 3.5.4.24 sepiapterin deaminase
EC 3.5.4.25 GTP cyclohydrolase II
EC 3.5.4.26 diaminohydroxyphosphoribosylaminopyrimidine deaminase
EC 3.5.4.27 methenyltetrahydromethanopterin cyclohydrolase
EC 3.5.4.28 S-adenosylhomocysteine deaminase
EC 3.5.4.29 GTP cyclohydrolase IIa
EC 3.5.4.30 dCTP deaminase (dUMP-forming)
EC 3.5.5 In Nitriles
EC 3.5.5.1 nitrilase
EC 3.5.5.2 ricinine nitrilase
EC 3.5.5.3 now EC 4.3.99.1
EC 3.5.5.4 cyanoalanine nitrilase
EC 3.5.5.5 arylacetonitrilase
EC 3.5.5.6 bromoxynil nitrilase
EC 3.5.5.7 aliphatic nitrilase
EC 3.5.5.8 thiocyanate hydrolase
EC 3.5.99 In Other Compounds
EC 3.5.99.1 riboflavinase
EC 3.5.99.2 thiaminase
EC 3.5.99.3 hydroxydechloroatrazine ethylaminohydrolase
EC 3.5.99.4 N-isopropylammelide isopropylaminohydrolase
EC 3.5.99.5 2-aminomuconate deaminase
EC 3.5.99.6 glucosamine-6-phosphate deaminase
EC 3.5.99.7 1-aminocyclopropane-1-carboxylate deaminase
EC 3.6 Acting on acid anhydrides
EC 3.6.1 In Phosphorus-Containing Anhydrides
EC 3.6.1.1 inorganic diphosphatase
EC 3.6.1.2 trimetaphosphatase
EC 3.6.1.3 adenosinetriphosphatase
EC 3.6.1.4 deleted, included in EC 3.6.1.3
EC 3.6.1.5 apyrase
EC 3.6.1.6 nucleoside-diphosphatase
EC 3.6.1.7 acylphosphatase
EC 3.6.1.8 ATP diphosphatase
EC 3.6.1.9 nucleotide diphosphatase
EC 3.6.1.10 endopolyphosphatase
EC 3.6.1.11 exopolyphosphatase
EC 3.6.1.12 dCTP diphosphatase
EC 3.6.1.13 ADP-ribose diphosphatase
EC 3.6.1.14 adenosine-tetraphosphatase
EC 3.6.1.15 nucleoside-triphosphatase
EC 3.6.1.16 CDP-glycerol diphosphatase
EC 3.6.1.17 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
EC 3.6.1.18 FAD diphosphatase
EC 3.6.1.19 nucleoside-triphosphate diphosphatase
EC 3.6.1.20 5'-acylphosphoadenosine hydrolase
EC 3.6.1.21 ADP-sugar diphosphatase
EC 3.6.1.22 NAD diphosphatase
EC 3.6.1.23 dUTP diphosphatase
EC 3.6.1.24 nucleoside phosphoacylhydrolase
EC 3.6.1.25 triphosphatase
EC 3.6.1.26 CDP-diacylglycerol-diphosphatase
EC 3.6.1.27 undecaprenyl-diphosphatase
EC 3.6.1.28 thiamine-triphosphatase
EC 3.6.1.29 bis(5'-adenosyl)-triphosphatase
EC 3.6.1.30 m7G(5')pppN diphosphatase
EC 3.6.1.31 phosphoribosyl-ATP diphosphatase
EC 3.6.1.32 now EC 3.6.4.1
EC 3.6.1.33 now EC 3.6.4.2
EC 3.6.1.34 now EC 3.6.3.14
EC 3.6.1.35 now EC 3.6.3.6
EC 3.6.1.36 now EC 3.6.3.10
EC 3.6.1.37 now EC 3.6.3.9
EC 3.6.1.38 now EC 3.6.3.8
EC 3.6.1.39 thymidine-triphosphatase
EC 3.6.1.40 guanosine-5'-triphosphate,3'-diphosphate diphosphatase
EC 3.6.1.41 bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
EC 3.6.1.42 guanosine-diphosphatase
EC 3.6.1.43 dolichyldiphosphatase
EC 3.6.1.44 oligosaccharide-diphosphodolichol diphosphatase
EC 3.6.1.45 UDP-sugar diphosphatase
EC 3.6.1.46 now EC 3.6.5.1
EC 3.6.1.47 now EC 3.6.5.2
EC 3.6.1.48 now EC 3.6.5.3
EC 3.6.1.49 now EC 3.6.5.4
EC 3.6.1.50 now EC 3.6.5.5
EC 3.6.1.51 now EC 3.6.5.6
EC 3.6.1.52 diphosphoinositol-polyphosphate diphosphatase
EC 3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
EC 3.6.2 In Sulfonyl-Containing Anhydrides
EC 3.6.2.1 adenylylsulfatase
EC 3.6.2.2 phosphoadenylylsulfatase
EC 3.6.3 Acting on acid anhydrides; catalysing transmembrane movement of substances
EC 3.6.3.1 Mg2+-ATPase
EC 3.6.3.2 Mg2+-importing ATPase
EC 3.6.3.3 Cd2+-exporting ATPase
EC 3.6.3.4 Cu2+-exporting ATPase
EC 3.6.3.5 Zn2+-exporting ATPase
EC 3.6.3.6 H+-exporting ATPase
EC 3.6.3.7 Na+-exporting ATPase
EC 3.6.3.8 Ca2+-transporting ATPase
EC 3.6.3.9 Na+/K+-exchanging ATPase
EC 3.6.3.10 H+/K+-exchanging ATPase
EC 3.6.3.11 Cl--transporting ATPase
EC 3.6.3.12 K+-transporting ATPase
EC 3.6.3.13 deleted
EC 3.6.3.14 H+-transporting two-sector ATPase
EC 3.6.3.15 Na+-transporting two-sector ATPase
EC 3.6.3.16 arsenite-transporting ATPase
EC 3.6.3.17 monosaccharide-transporting ATPase
EC 3.6.3.18 oligosaccharide-transporting ATPase
EC 3.6.3.19 maltose-transporting ATPase
EC 3.6.3.20 glycerol-3-phosphate-transporting ATPase
EC 3.6.3.21 polar-amino-acid-transporting ATPase
EC 3.6.3.22 nonpolar-amino-acid-transporting ATPase
EC 3.6.3.23 oligopeptide-transporting ATPase
EC 3.6.3.24 nickel-transporting ATPase
EC 3.6.3.25 sulfate-transporting ATPase
EC 3.6.3.26 nitrate-transporting ATPase
EC 3.6.3.27 phosphate-transporting ATPase
EC 3.6.3.28 phosphonate-transporting ATPase
EC 3.6.3.29 molybdate-transporting ATPase
EC 3.6.3.30 Fe3+-transporting ATPase
EC 3.6.3.31 polyamine-transporting ATPase
EC 3.6.3.32 quaternary-amine-transporting ATPase
EC 3.6.3.33 vitamin B12-transporting ATPase
EC 3.6.3.34 iron-chelate-transporting ATPase
EC 3.6.3.35 manganese-transporting ATPase
EC 3.6.3.36 taurine-transporting ATPase
EC 3.6.3.37 guanine-transporting ATPase
EC 3.6.3.38 capsular-polysaccharide-transporting ATPase
EC 3.6.3.39 lipopolysaccharide-transporting ATPase
EC 3.6.3.40 teichoic-acid-transporting ATPase
EC 3.6.3.41 heme-transporting ATPase
EC 3.6.3.42 β-glucan-transporting ATPase
EC 3.6.3.43 peptide-transporting ATPase
EC 3.6.3.44 xenobiotic-transporting ATPase
EC 3.6.3.45 now EC 3.6.3.44
EC 3.6.3.46 cadmium-transporting ATPase
EC 3.6.3.47 fatty-acyl-CoA-transporting ATPase
EC 3.6.3.48 α-factor-transporting ATPase
EC 3.6.3.49 channel-conductance-controlling ATPase
EC 3.6.3.50 protein-secreting ATPase
EC 3.6.3.51 mitochondrial protein-transporting ATPase
EC 3.6.3.52 chloroplast protein-transporting ATPase
EC 3.6.3.53 Ag+-exporting ATPase
EC 3.6.4 Acting on ATP; involved in cellular and subcellular movement
EC 3.6.4.1 myosin ATPase
EC 3.6.4.2 dynein ATPase
EC 3.6.4.3 microtubule-severing ATPase
EC 3.6.4.4 plus-end-directed kinesin ATPase
EC 3.6.4.5 minus-end-directed kinesin ATPase
EC 3.6.4.6 vesicle-fusing ATPase
EC 3.6.4.7 peroxisome-assembly ATPase
EC 3.6.4.8 proteasome ATPase
EC 3.6.4.9 chaperonin ATPase
EC 3.6.4.10 non-chaperonin molecular chaperone ATPase
EC 3.6.4.11 nucleoplasmin ATPase
EC 3.6.4.12 DNA helicase
EC 3.6.4.13 RNA helicase
EC 3.6.5 Acting on GTP; involved in cellular and subcellular movement
EC 3.6.5.1 heterotrimeric G-protein GTPase
EC 3.6.5.2 small monomeric GTPase
EC 3.6.5.3 protein-synthesizing GTPase
EC 3.6.5.4 signal-recognition-particle GTPase
EC 3.6.5.5 dynamin GTPase
EC 3.6.5.6 tubulin GTPase
EC 3.7 Acting on carbon-carbon bonds
EC 3.7.1 In Ketonic Substances
EC 3.7.1.1 oxaloacetase
EC 3.7.1.2 fumarylacetoacetase
EC 3.7.1.3 kynureninase
EC 3.7.1.4 phloretin hydrolase
EC 3.7.1.5 acylpyruvate hydrolase
EC 3.7.1.6 acetylpyruvate hydrolase
EC 3.7.1.7 β-diketone hydrolase
EC 3.7.1.8 2,6-dioxo-6-phenylhexa-3-enoate hydrolase
EC 3.7.1.9 2-hydroxymuconate-semialdehyde hydrolase
EC 3.7.1.10 cyclohexane-1,3-dione hydrolase
EC 3.7.1.11 cyclohexane-1,2-dione hydrolase
EC 3.8 Acting on halide bonds
EC 3.8.1 In C-Halide Compounds
EC 3.8.1.1 alkylhalidase
EC 3.8.1.2 (S)-2-haloacid dehalogenase
EC 3.8.1.3 haloacetate dehalogenase
EC 3.8.1.4 now EC 1.97.1.10
EC 3.8.1.5 haloalkane dehalogenase
EC 3.8.1.6 4-chlorobenzoate dehalogenase
EC 3.8.1.7 4-chlorobenzoyl-CoA dehalogenase
EC 3.8.1.8 atrazine chlorohydrolase
EC 3.8.1.9 (R)-2-haloacid dehalogenase
EC 3.8.1.10 2-haloacid dehalogenase (configuration-inverting)
EC 3.8.1.11 2-haloacid dehalogenase (configuration-retaining)
EC 3.8.2 In P-Halide Compounds
EC 3.8.2.1 now EC 3.1.8.2
EC 3.9 Acting on phosphorus-nitrogen bonds
EC 3.9.1 (only sub-subclass identified to date)
EC 3.9.1.1 phosphoamidase
EC 3.10 Acting on sulfur-nitrogen bonds
EC 3.10.1 (only sub-subclass identified to date)
EC 3.10.1.1 N-sulfoglucosamine sulfohydrolase
EC 3.10.1.2 cyclamate sulfohydrolase
EC 3.11 Acting on carbon-phosphorus bonds
EC 3.11.1 (only sub-subclass identified to date)
EC 3.11.1.1 phosphonoacetaldehyde hydrolase
EC 3.11.1.2 phosphonoacetate hydrolase
EC 3.11.1.3 phosphonopyruvate hydrolase

EC 3.12 Acting on sulfur-sulfur bonds


EC 3.12.1 (only sub-subclass identified to date)
EC 3.12.1.1 trithionate hydrolase
EC 3.13 Acting on carbon-sulfur bonds
EC 3.13.1
EC 3.13.1.1 UDP-sulfoquinovose synthase
EC 3.13.1.2 deleted probably EC 4.4.1.21
EC 3.13.1.3 2'-hydroxybiphenyl-2-sulfinate desulfinase
EC 4 Lyases
Enzim-enzim yang mengkatalisis pembuangan gugus dari substrat dengan mekanisme yang
lain dari pada hidrolisis, dan meninggalkan ikatan rangkap.

XY

C-C = X-Y + C=C


EC 4.1 Carbon-carbon lyases
EC 4.1.1 Carboxy-Lyases
EC 4.1.1.1 pyruvate decarboxylase
EC 4.1.1.2 oxalate decarboxylase
EC 4.1.1.3 oxaloacetate decarboxylase
EC 4.1.1.4 acetoacetate decarboxylase
EC 4.1.1.5 acetolactate decarboxylase
EC 4.1.1.6 aconitate decarboxylase
EC 4.1.1.7 benzoylformate decarboxylase
EC 4.1.1.8 oxalyl-CoA decarboxylase
EC 4.1.1.9 malonyl-CoA decarboxylase
EC 4.1.1.10 deleted, included in EC 4.1.1.12
EC 4.1.1.11 aspartate 1-decarboxylase
EC 4.1.1.12 aspartate 4-decarboxylase
EC 4.1.1.13 deleted
EC 4.1.1.14 valine decarboxylase
EC 4.1.1.15 glutamate decarboxylase
EC 4.1.1.16 hydroxyglutamate decarboxylase
EC 4.1.1.17 ornithine decarboxylase
EC 4.1.1.18 lysine decarboxylase
EC 4.1.1.19 arginine decarboxylase
EC 4.1.1.20 diaminopimelate decarboxylase
EC 4.1.1.21 phosphoribosylaminoimidazole carboxylase
EC 4.1.1.21 phosphoribosylaminoimidazole carboxylase
EC 4.1.1.22 histidine decarboxylase
EC 4.1.1.23 orotidine-5'-phosphate decarboxylase
EC 4.1.1.24 aminobenzoate decarboxylase
EC 4.1.1.25 tyrosine decarboxylase
EC 4.1.1.26 deleted, included in EC 4.1.1.28
EC 4.1.1.27 deleted, included in EC 4.1.1.28
EC 4.1.1.28 aromatic-L-amino-acid decarboxylase
EC 4.1.1.29 sulfoalanine decarboxylase
EC 4.1.1.30 pantothenoylcysteine decarboxylase
EC 4.1.1.31 phosphoenolpyruvate carboxylase
EC 4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
EC 4.1.1.33 diphosphomevalonate decarboxylase
EC 4.1.1.34 dehydro-L-gulonate decarboxylase
EC 4.1.1.35 UDP-glucuronate decarboxylase
EC 4.1.1.36 phosphopantothenoylcysteine decarboxylase
EC 4.1.1.37 uroporphyrinogen decarboxylase
EC 4.1.1.38 phosphoenolpyruvate carboxykinase (diphosphate)
EC 4.1.1.39 ribulose-bisphosphate carboxylase
EC 4.1.1.40 hydroxypyruvate decarboxylase
EC 4.1.1.41 methylmalonyl-CoA decarboxylase
EC 4.1.1.42 carnitine decarboxylase
EC 4.1.1.43 phenylpyruvate decarboxylase
EC 4.1.1.44 4-carboxymuconolactone decarboxylase
EC 4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase
EC 4.1.1.46 o-pyrocatechuate decarboxylase
EC 4.1.1.47 tartronate-semialdehyde synthase
EC 4.1.1.48 indole-3-glycerol-phosphate synthase
EC 4.1.1.49 phosphoenolpyruvate carboxykinase (ATP)
EC 4.1.1.50 adenosylmethionine decarboxylase
EC 4.1.1.51 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase
EC 4.1.1.52 6-methylsalicylate decarboxylase
EC 4.1.1.53 phenylalanine decarboxylase
EC 4.1.1.54 dihydroxyfumarate decarboxylase
EC 4.1.1.55 4,5-dihydroxyphthalate decarboxylase
EC 4.1.1.56 3-oxolaurate decarboxylase
EC 4.1.1.57 methionine decarboxylase
EC 4.1.1.58 orsellinate decarboxylase
EC 4.1.1.59 gallate decarboxylase
EC 4.1.1.60 stipitatonate decarboxylase
EC 4.1.1.61 4-hydroxybenzoate decarboxylase
EC 4.1.1.62 gentisate decarboxylase
EC 4.1.1.63 protocatechuate decarboxylase
EC 4.1.1.64 2,2-dialkylglycine decarboxylase (pyruvate)
EC 4.1.1.65 phosphatidylserine decarboxylase
EC 4.1.1.66 uracil-5-carboxylate decarboxylase
EC 4.1.1.67 UDP-galacturonate decarboxylase
EC 4.1.1.68 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase
EC 4.1.1.69 3,4-dihydroxyphthalate decarboxylase
EC 4.1.1.70 glutaconyl-CoA decarboxylase
EC 4.1.1.71 2-oxoglutarate decarboxylase
EC 4.1.1.72 branched-chain-2-oxoacid decarboxylase
EC 4.1.1.73 tartrate decarboxylase
EC 4.1.1.74 indolepyruvate decarboxylase
EC 4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase
EC 4.1.1.76 arylmalonate decarboxylase
EC 4.1.1.77 4-oxalocrotonate decarboxylase
EC 4.1.1.78 acetylenedicarboxylate decarboxylase
EC 4.1.1.79 sulfopyruvate decarboxylase
EC 4.1.1.80 4-hydroxyphenylpyruvate decarboxylase
EC 4.1.1.81 threonine-phosphate decarboxylase
EC 4.1.1.82 phosphonopyruvate decarboxylase
EC 4.1.1.83 4-hydroxyphenylacetate decarboxylase
EC 4.1.1.84 D-dopachrome decarboxylase
EC 4.1.1.85 3-dehydro-L-gulonate-6-phosphate decarboxylase
EC 4.1.1.86 diaminobutyrate decarboxylase
EC 4.1.1.87 malonyl-S-ACP decarboxylase
EC 4.1.1.88 biotin-independent malonate decarboxylase
EC 4.1.1.89 biotin-dependent malonate decarboxylase
EC 4.1.1.90 peptidyl-glutamate 4-carboxylase
EC 4.1.2 Aldehyde-Lyases
EC 4.1.2.1 deleted, included in EC 4.1.3.16
EC 4.1.2.2 ketotetrose-phosphate aldolase
EC 4.1.2.3 deleted
EC 4.1.2.4 deoxyribose-phosphate aldolase
EC 4.1.2.5 threonine aldolase
EC 4.1.2.6 deleted
EC 4.1.2.7 deleted, included in EC 4.1.2.13
EC 4.1.2.8 indole-3-glycerol-phosphate lyase
EC 4.1.2.9 phosphoketolase
EC 4.1.2.10 mandelonitrile lyase
EC 4.1.2.11 hydroxymandelonitrile lyase
EC 4.1.2.12 ketopantoaldolase
EC 4.1.2.13 fructose-bisphosphate aldolase
EC 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase
EC 4.1.2.15 now EC 2.5.1.54
EC 4.1.2.16 now EC 2.5.1.55
EC 4.1.2.17 L-fuculose-phosphate aldolase
EC 4.1.2.18 2-dehydro-3-deoxy-L-pentonate aldolase
EC 4.1.2.19 rhamnulose-1-phosphate aldolase
EC 4.1.2.20 2-dehydro-3-deoxyglucarate aldolase
EC 4.1.2.21 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
EC 4.1.2.22 fructose-6-phosphate phosphoketolase
EC 4.1.2.23 3-deoxy-D-manno-octulosonate aldolase
EC 4.1.2.24 dimethylaniline-N-oxide aldolase
EC 4.1.2.25 dihydroneopterin aldolase
EC 4.1.2.26 phenylserine aldolase
EC 4.1.2.27 sphinganine-1-phosphate aldolase
EC 4.1.2.28 2-dehydro-3-deoxy-D-pentonate aldolase
EC 4.1.2.29 5-dehydro-2-deoxyphosphogluconate aldolase
EC 4.1.2.30 17α-hydroxyprogesterone aldolase
EC 4.1.2.31 deleted, included in EC 4.1.3.16
EC 4.1.2.32 trimethylamine-oxide aldolase
EC 4.1.2.33 fucosterol-epoxide lyase
EC 4.1.2.34 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase
EC 4.1.2.35 propioin synthase
EC 4.1.2.36 lactate aldolase
EC 4.1.2.37 hydroxynitrilase
EC 4.1.2.38 benzoin aldolase
EC 4.1.2.39 deleted, same as EC 4.1.2.37
EC 4.1.2.40 tagatose-bisphosphate aldolase
EC 4.1.2.41 vanillin synthase
EC 4.1.2.42 D-threonine aldolase
EC 4.1.2.43 3-hexulose-6-phosphate synthase
EC 4.1.2.44 benzoyl-CoA-dihydrodiol lyase
EC 4.1.3 Oxo-Acid-Lyases
EC 4.1.3.1 isocitrate lyase
EC 4.1.3.2 now EC 2.3.3.9
EC 4.1.3.3 N-acetylneuraminate lyase
EC 4.1.3.4 hydroxymethylglutaryl-CoA lyase
EC 4.1.3.5 now EC 2.3.3.10
EC 4.1.3.6 citrate (pro-3S)-lyase
EC 4.1.3.7 now EC 2.3.3.1
EC 4.1.3.8 now EC 2.3.3.8
EC 4.1.3.9 now EC 2.3.3.11
EC 4.1.3.10 now EC 2.3.3.7
EC 4.1.3.11 now EC 2.3.3.12
EC 4.1.3.12 now EC 2.3.3.13
EC 4.1.3.13 oxalomalate lyase
EC 4.1.3.14 3-hydroxyaspartate aldolase
EC 4.1.3.15 now EC 2.2.1.5
EC 4.1.3.16 4-hydroxy-2-oxoglutarate aldolase
EC 4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate aldolase
EC 4.1.3.18 now EC 2.2.1.6
EC 4.1.3.19 now EC 2.5.1.56
EC 4.1.3.20 now EC 2.5.1.57
EC 4.1.3.21 now EC 2.3.3.14
EC 4.1.3.22 citramalate lyase
EC 4.1.3.23 now EC 2.3.3.2
EC 4.1.3.24 malyl-CoA lyase
EC 4.1.3.25 citramalyl-CoA lyase
EC 4.1.3.26 3-hydroxy-3-isohexenylglutaryl-CoA lyase
EC 4.1.3.27 anthranilate synthase
EC 4.1.3.28 now EC 2.3.3.3
EC 4.1.3.29 now EC 2.3.3.4
EC 4.1.3.30 methylisocitrate lyase
EC 4.1.3.31 now EC 2.3.3.5
EC 4.1.3.32 2,3-dimethylmalate lyase
EC 4.1.3.33 now EC 2.3.3.6
EC 4.1.3.34 citryl-CoA lyase
EC 4.1.3.35 (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase
EC 4.1.3.36 naphthoate synthase
EC 4.1.3.37 now EC 2.2.1.7
EC 4.1.3.38 aminodeoxychorismate lyase
EC 4.1.3.39 4-hydroxy-2-oxovalerate aldolase
EC 4.1.3.40 chorismate lyase

EC 4.1.99 Other Carbon-Carbon Lyases


EC 4.1.99.1 tryptophanase
EC 4.1.99.2 tyrosine phenol-lyase
EC 4.1.99.3 deoxyribodipyrimidine photo-lyase
EC 4.1.99.4 now EC 3.5.99.7
EC 4.1.99.5 octadecanal decarbonylase
EC 4.1.99.6 now EC 4.2.3.6
EC 4.1.99.7 now EC 4.2.3.9
EC 4.1.99.8 now EC 4.2.3.14
EC 4.1.99.9 now EC 4.2.3.15
EC 4.1.99.10 now EC 4.2.3.16
EC 4.1.99.11 benzylsuccinate synthase
EC 4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase
EC 4.1.99.13 (6-4)DNA photolyase
EC 4.1.99.14 R-specific spore photoproduct lyase
EC 4.1.99.15 S-specific spore photoproduct lyase
EC 4.2 Carbon-oxygen lyases
EC 4.2.1 Hydro-Lyases
EC 4.2.1.1 carbonate dehydratase
EC 4.2.1.2 fumarate hydratase
EC 4.2.1.3 aconitate hydratase
EC 4.2.1.4 citrate dehydratase
EC 4.2.1.5 arabinonate dehydratase
EC 4.2.1.6 galactonate dehydratase
EC 4.2.1.7 altronate dehydratase
EC 4.2.1.8 mannonate dehydratase
EC 4.2.1.9 dihydroxy-acid dehydratase
EC 4.2.1.10 3-dehydroquinate dehydratase
EC 4.2.1.11 phosphopyruvate hydratase
EC 4.2.1.12 phosphogluconate dehydratase
EC 4.2.1.13 now EC 4.3.1.17
EC 4.2.1.14 now EC 4.3.1.17
EC 4.2.1.15 now EC 4.4.1.1
EC 4.2.1.16 now EC 4.3.1.17
EC 4.2.1.17 enoyl-CoA hydratase
EC 4.2.1.18 methylglutaconyl-CoA hydratase
EC 4.2.1.19 imidazoleglycerol-phosphate dehydratase
EC 4.2.1.20 tryptophan synthase
EC 4.2.1.21 now EC 4.2.1.22
EC 4.2.1.22 cystathionine β-synthase
EC 4.2.1.23 deleted
EC 4.2.1.24 porphobilinogen synthase
EC 4.2.1.25 L-arabinonate dehydratase
EC 4.2.1.26 now EC 4.3.1.9
EC 4.2.1.27 acetylenecarboxylate hydratase
EC 4.2.1.28 propanediol dehydratase
EC 4.2.1.29 now EC 4.99.1.6
EC 4.2.1.30 glycerol dehydratase
EC 4.2.1.31 maleate hydratase
EC 4.2.1.32 L(+)-tartrate dehydratase
EC 4.2.1.33 3-isopropylmalate dehydratase
EC 4.2.1.34 (S)-2-methylmalate dehydratase
EC 4.2.1.35 (R)-2-methylmalate dehydratase
EC 4.2.1.36 homoaconitate hydratase
EC 4.2.1.37 now EC 3.3.2.4
EC 4.2.1.38 now EC 4.3.1.17
EC 4.2.1.39 gluconate dehydratase
EC 4.2.1.40 glucarate dehydratase
EC 4.2.1.41 5-dehydro-4-deoxyglucarate dehydratase
EC 4.2.1.42 galactarate dehydratase
EC 4.2.1.43 2-dehydro-3-deoxy-L-arabinonate dehydratase
EC 4.2.1.44 myo-inosose-2 dehydratase
EC 4.2.1.45 CDP-glucose 4,6-dehydratase
EC 4.2.1.46 dTDP-glucose 4,6-dehydratase
EC 4.2.1.47 GDP-mannose 4,6-dehydratase
EC 4.2.1.48 D-glutamate cyclase
EC 4.2.1.49 urocanate hydratase
EC 4.2.1.50 pyrazolylalanine synthase
EC 4.2.1.51 prephenate dehydratase
EC 4.2.1.52 dihydrodipicolinate synthase
EC 4.2.1.53 oleate hydratase
EC 4.2.1.54 lactoyl-CoA dehydratase
EC 4.2.1.55 3-hydroxybutyryl-CoA dehydratase
EC 4.2.1.56 itaconyl-CoA hydratase
EC 4.2.1.57 isohexenylglutaconyl-CoA hydratase
EC 4.2.1.58 crotonoyl-[acyl-carrier-protein] hydratase
EC 4.2.1.59 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase
EC 4.2.1.60 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
EC 4.2.1.61 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase
EC 4.2.1.62 5α-hydroxysteroid dehydratase
EC 4.2.1.63 now EC 3.3.2.3
EC 4.2.1.64 now EC 3.3.2.3
EC 4.2.1.65 3-cyanoalanine hydratase
EC 4.2.1.66 cyanide hydratase
EC 4.2.1.67 D-fuconate dehydratase
EC 4.2.1.68 L-fuconate dehydratase
EC 4.2.1.69 cyanamide hydratase
EC 4.2.1.70 pseudouridylate synthase
EC 4.2.1.71 identical to EC 4.2.1.27
EC 4.2.1.72 now EC 4.1.1.78
EC 4.2.1.73 protoaphin-aglucone dehydratase (cyclizing)
EC 4.2.1.74 long-chain-enoyl-CoA hydratase
EC 4.2.1.75 uroporphyrinogen-III synthase
EC 4.2.1.76 UDP-glucose 4,6-dehydratase
EC 4.2.1.77 trans-L-3-hydroxyproline dehydratase
EC 4.2.1.78 (S)-norcoclaurine synthase
EC 4.2.1.79 2-methylcitrate dehydratase
EC 4.2.1.80 2-oxopent-4-enoate hydratase
EC 4.2.1.81 D(-)-tartrate dehydratase
EC 4.2.1.82 xylonate dehydratase
EC 4.2.1.83 4-oxalmesaconate hydratase
EC 4.2.1.84 nitrile hydratase
EC 4.2.1.85 dimethylmaleate hydratase
EC 4.2.1.86 deleted, identical to EC 4.2.1.98
EC 4.2.1.87 octopamine dehydratase
EC 4.2.1.88 synephrine dehydratase
EC 4.2.1.89 carnitine dehydratase
EC 4.2.1.90 L-rhamnonate dehydratase
EC 4.2.1.91 arogenate dehydratase
EC 4.2.1.92 hydroperoxide dehydratase
EC 4.2.1.93 ATP-dependent NAD(P)H-hydrate dehydratase
EC 4.2.1.94 scytalone dehydratase
EC 4.2.1.95 kievitone hydratase
EC 4.2.1.96 4a-hydroxytetrahydrobiopterin dehydratase
EC 4.2.1.97 phaseollidin hydratase
EC 4.2.1.98 16α-hydroxyprogesterone dehydratase
EC 4.2.1.99 2-methylisocitrate dehydratase
EC 4.2.1.100 cyclohexa-1,5-dienecarbonyl-CoA hydratase
EC 4.2.1.101 trans-feruloyl-CoA hydratase
EC 4.2.1.102 now EC 4.2.1.100
EC 4.2.1.103 cyclohexyl-isocyanide hydratase
EC 4.2.1.104 cyanase
EC 4.2.1.105 2-hydroxyisoflavanone dehydratase
EC 4.2.1.106 bile-acid 7α-dehydratase
EC 4.2.1.107 3α,7α,12αtrihydroxy-5β-cholest-24-enoyl-CoA dehydratase
EC 4.2.1.108 ectoine synthase
EC 4.2.1.109 methylthioribulose 1-phosphate dehydratase
EC 4.2.1.110 aldos-2-ulose dehydratase
EC 4.2.1.111 1,5-anhydro-D-fructose dehydratase
EC 4.2.1.112 acetylene hydratase
EC 4.2.1.113 o-succinylbenzoate synthase
EC 4.2.1.114 methanogen homoaconitase
EC 4.2.1.115 UDP-N-acetylglucosamine 4,6-dehydratase (inverting)
EC 4.2.1.116 3-hydroxypropionyl-CoA dehydratase
EC 4.2.1.117 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
EC 4.2.1.118 3-dehydroshikimate dehydratase
EC 4.2.1.119 enoyl-CoA hydratase 2
EC 4.2.1.120 4-hydroxybutanoyl-CoA dehydratase
EC 4.2.2 Acting on Polysaccharides
EC 4.2.2.1 hyaluronate lyase
EC 4.2.2.2 pectate lyase
EC 4.2.2.3 poly(β-D-mannuronate) lyase
EC 4.2.2.4 now EC 4.2.2.20 and >EC 4.2.2.21
EC 4.2.2.5 chondroitin AC lyase
EC 4.2.2.6 oligogalacturonide lyase
EC 4.2.2.7 heparin lyase
EC 4.2.2.8 heparin-sulfate lyase
EC 4.2.2.9 pectate disaccharide-lyase
EC 4.2.2.10 pectin lyase
EC 4.2.2.11 poly(α-L-guluronate) lyase
EC 4.2.2.12 xanthan lyase
EC 4.2.2.13 exo-(1 4)-α-D-glucan lyase
EC 4.2.2.14 glucuronan lyase
EC 4.2.2.15 anhydrosialidase
EC 4.2.2.16 levan fructotransferase (DFA-IV-forming)
EC 4.2.2.17 inulin fructotransferase (DFA-I-forming)
EC 4.2.2.18 inulin fructotransferase (DFA-III-forming)
EC 4.2.2.19 chondroitin B lyase
EC 4.2.2.20 chondroitin-sulfate-ABC endolyase
EC 4.2.2.21 chondroitin-sulfate-ABC exolyase
EC 4.2.2.22 pectate trisaccharide-lyase
EC 4.2.3 Acting on Phosphates
EC 4.2.3.1 threonine synthase
EC 4.2.3.2 ethanolamine-phosphate phospho-lyase
EC 4.2.3.3 methylglyoxal synthase
EC 4.2.3.4 3-dehydroquinate synthase
EC 4.2.3.5 chorismate synthase
EC 4.2.3.6 trichodiene synthase
EC 4.2.3.7 pentalenene synthase
EC 4.2.3.8 casbene synthase
EC 4.2.3.9 aristolochene synthase
EC 4.2.3.10 (-)-endo-fenchol synthase
EC 4.2.3.11 sabinene-hydrate synthase
EC 4.2.3.12 6-pyruvoyltetrahydropterin synthase
EC 4.2.3.13 (+)-δ-cadinene synthase
EC 4.2.3.14 pinene synthase
EC 4.2.3.15 myrcene synthase
EC 4.2.3.16 (4S)-limonene synthase
EC 4.2.3.17 taxadiene synthase
EC 4.2.3.18 abietadiene synthase
EC 4.2.3.19 ent-kaurene synthase
EC 4.2.3.20 (R)-limonene synthase
EC 4.2.3.21 vetispiradiene synthase
EC 4.2.3.22 germacradienol synthase
EC 4.2.3.23 germacrene-A synthase
EC 4.2.3.24 amorpha-4,11-diene synthase
EC 4.2.3.25 S-linalool synthase
EC 4.2.3.26 R-linalool synthase
EC 4.2.3.27 isoprene synthase
EC 4.2.3.28 ent-cassa-12,15-diene synthase
EC 4.2.3.29 ent-sandaracopimaradiene synthase
EC 4.2.3.30 ent-pimara-8(14),15-diene synthase
EC 4.2.3.31 ent-pimara-9(11),15-diene synthase
EC 4.2.3.32 levopimaradiene synthase
EC 4.2.3.33 stemar-13-ene synthase
EC 4.2.3.34 stemod-13(17)-ene synthase
EC 4.2.3.35 syn-pimara-7,15-diene synthase
EC 4.2.3.36 terpentetriene synthase
EC 4.2.3.37 epi-isozizaene synthase
EC 4.2.3.38 α-bisabolene synthase
EC 4.2.3.39 epi-cedrol synthase
EC 4.2.3.40 (Z)-γ-bisabolene synthase
EC 4.2.3.41 elisabethatriene synthase
EC 4.2.3.42 aphidicolan-16β-ol synthase
EC 4.2.3.43 fusicocca-2,10(14)-diene synthase
EC 4.2.3.44 isopimara-7,15-diene synthase
EC 4.2.3.45 phyllocladan-16α-ol synthase
EC 4.2.99 Other Carbon-Oxygen Lyases
EC 4.2.99.1 now EC 4.2.2.2
EC 4.2.99.2 now EC 4.2.3.1
EC 4.2.99.3 now EC 4.2.2.2
EC 4.2.99.4 now EC 4.2.2.3
EC 4.2.99.5 deleted
EC 4.2.99.6 deleted, included in EC 4.2.2.4 and EC 4.2.2.5
EC 4.2.99.7 now EC 4.2.3.2
EC 4.2.99.8 now EC 2.5.1.47
EC 4.2.99.9 now EC 2.5.1.48
EC 4.2.99.10 now EC 2.5.1.49
EC 4.2.99.11 now EC 4.2.3.3
EC 4.2.99.12 carboxymethyloxysuccinate lyase
EC 4.2.99.13 now EC 2.5.1.50
EC 4.2.99.14 now EC 2.5.1.51
EC 4.2.99.15 now EC 2.5.1.52
EC 4.2.99.16 now EC 2.5.1.53
EC 4.2.99.17 now EC 2.5.1.51
EC 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase
EC 4.2.99.19 now EC 4.4.1.23
EC 4.2.99.20 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase

EC 4.3 Carbon-nitrogen lyases


EC 4.3.1 Ammonia-Lyases
EC 4.3.1.1 aspartate ammonia-lyase
EC 4.3.1.2 methylaspartate ammonia-lyase
EC 4.3.1.3 histidine ammonia-lyase
EC 4.3.1.4 formiminotetrahydrofolate cyclodeaminase
EC 4.3.1.5 transferred, now divided into EC 4.3.1.23, EC 4.3.1.24 and EC 4.3.1.25
EC 4.3.1.6 β-alanyl-CoA ammonia-lyase
EC 4.3.1.7 ethanolamine ammonia-lyase
EC 4.3.1.8 now EC 2.5.1.61
EC 4.3.1.9 glucosaminate ammonia-lyase
EC 4.3.1.10 serine-sulfate ammonia-lyase
EC 4.3.1.11 deleted
EC 4.3.1.12 ornithine cyclodeaminase
EC 4.3.1.13 carbamoyl-serine ammonia-lyase
EC 4.3.1.14 3-aminobutyryl-CoA ammonia-lyase
EC 4.3.1.15 diaminopropionate ammonia-lyase
EC 4.3.1.16 threo-3-hydroxyaspartate ammonia-lyase
EC 4.3.1.17 L-serine ammonia-lyase
EC 4.3.1.18 D-serine ammonia-lyase
EC 4.3.1.19 threonine ammonia-lyase
EC 4.3.1.20 erythro-3-hydroxyaspartate ammonia-lyase
EC 4.3.1.21 identical to EC 4.3.1.9
EC 4.3.1.22 3,4-dihydroxyphenylalanine reductive deaminase
EC 4.3.1.23 tyrosine ammonia-lyase
EC 4.3.1.24 phenylalanine ammonia-lyase
EC 4.3.1.25 phenylalanine/tyrosine ammonia-lyase
EC 4.3.1.26 chromopyrrolate synthase
EC 4.3.2 Lyases Acting on Amides, Amidines, etc.
EC 4.3.2.1 argininosuccinate lyase
EC 4.3.2.2 adenylosuccinate lyase
EC 4.3.2.3 ureidoglycolate lyase
EC 4.3.2.4 purine imidazole-ring cyclase
EC 4.3.2.5 peptidylamidoglycolate lyase
EC 4.3.3 Amine-Lyases
EC 4.3.3.1 3-ketovalidoxylamine C-N-lyase
EC 4.3.3.2 strictosidine synthase
EC 4.3.3.3 deacetylisoipecoside synthase
EC 4.3.3.4 deacetylipecoside synthase
EC 4.3.3.5 4'-demethylrebeccamycin synthase
EC 4.3.99 Other Carbon-Nitrogen Lyases
EC 4.3.99.1 now EC 4.2.1.104
EC 4.3.99.2 carboxybiotin decarboxylase
This subclass contains the enzymes that release ammonia or one of its derivatives, with the
formation of a double bond or ring. Some catalyse the actual elimination of the ammonia,
amine or amide, e.g.
>CH-CH(-NH-R)- >C=CH- + NH2-R

Others, however, catalyse elimination of another component, e.g. water, which is followed by
spontaneous reactions that lead to breakage of the C-N bond, e.g.

as in EC 4.3.1.17 (L-serine ammonia-lyase), so that the overall reaction is

>C(-OH)-CH(-NH2)- >CH2-CO- + NH3

i.e., an elimination with rearrangement.


EC 4.4 Carbon-sulfur lyases
EC 4.4.1 (only sub-subclass identified to date)
EC 4.4.1.1 cystathionine γ-lyase
EC 4.4.1.2 homocysteine desulfhydrase
EC 4.4.1.3 dimethylpropiothetin dethiomethylase
EC 4.4.1.4 alliin lyase
EC 4.4.1.5 lactoylglutathione lyase
EC 4.4.1.6 S-alkylcysteine lyase
EC 4.4.1.7 deleted, included in EC 2.5.1.18
EC 4.4.1.8 cystathionine β-lyase
EC 4.4.1.9 L-3-cyanoalanine synthase
EC 4.4.1.10 cysteine lyase
EC 4.4.1.11 methionine γ-lyase
EC 4.4.1.12 deleted
EC 4.4.1.13 cysteine-S-conjugate β-lyase
EC 4.4.1.14 1-aminocyclopropane-1-carboxylate synthase
EC 4.4.1.15 D-cysteine desulfhydrase
EC 4.4.1.16 selenocysteine lyase
EC 4.4.1.17 holocytochrome-c synthase
EC 4.4.1.18 now EC 1.8.3.5
EC 4.4.1.19 phosphosulfolactate synthase
EC 4.4.1.20 leukotriene-C4 synthase
EC 4.4.1.21 S-ribosylhomocysteine lyase
EC 4.4.1.22 S-(hydroxymethyl)glutathione synthase
EC 4.4.1.23 2-hydroxypropyl-CoM lyase
EC 4.4.1.24 sulfolactate sulfo-lyase
EC 4.4.1.25 L-cysteate sulfo-lyase
EC 4.5 Carbon-halide lyases
EC 4.5.1 (only sub-subclass identified to date)
EC 4.5.1.1 DDT-dehydrochlorinase
EC 4.5.1.2 3-chloro-D-alanine dehydrochlorinase
EC 4.5.1.3 dichloromethane dehalogenase
EC 4.5.1.4 L-2-amino-4-chloropent-4-enoate dehydrochlorinase
EC 4.5.1.5 S-carboxymethylcysteine synthase
EC 4.6 Phosphorus-oxygen lyases
EC 4.6.1 (only sub-subclass identified to date)
EC 4.6.1.1 adenylate cyclase
EC 4.6.1.2 guanylate cyclase
EC 4.6.1.3 now EC 4.2.3.4
EC 4.6.1.4 now EC 4.2.3.5
EC 4.6.1.5 now EC 4.2.3.7
EC 4.6.1.6 cytidylate cyclase
EC 4.6.1.7 now EC 4.2.3.8
EC 4.6.1.8 now EC 4.2.3.10
EC 4.6.1.9 now EC 4.2.3.11
EC 4.6.1.10 now EC 4.2.3.12
EC 4.6.1.11 now EC 4.2.3.13
EC 4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
EC 4.6.1.13 phosphatidylinositol diacylglycerol-lyase
EC 4.6.1.14 glycosylphosphatidylinositol diacylglycerol-lyase
EC 4.6.1.15 FAD-AMP lyase (cyclizing)
EC 4.99 Other lyases
EC 4.99.1 Sole sub-subclass for lyases that do not belong in the other subclasses
EC 4.99.1.1 ferrochelatase
EC 4.99.1.2 alkylmercury lyase
EC 4.99.1.3 sirohydrochlorin cobaltochelatase
EC 4.99.1.4 sirohydrochlorin ferrochelatase
EC 4.99.1.5 aliphatic aldoxime dehydratase
EC 4.99.1.6 indoleacetaldoxime dehydratase
EC 4.99.1.7 phenylacetaldoxime dehydratase
EC 4.99.1.8 heme ligase
EC 5 Isomerases
Yang termasuk kelas ini adalah semua enzim yang mengkatalisis interkonversi isomer-isomer
optik, geometrik, atau posisi.
EC 5.1 Racemases and epimerases
EC 5.1.1 Acting on Amino Acids and Derivatives
EC 5.1.1.1 alanine racemase
EC 5.1.1.2 methionine racemase
EC 5.1.1.3 glutamate racemase
EC 5.1.1.4 proline racemase
EC 5.1.1.5 lysine racemase
EC 5.1.1.6 threonine racemase
EC 5.1.1.7 diaminopimelate epimerase
EC 5.1.1.8 4-hydroxyproline epimerase
EC 5.1.1.9 arginine racemase
EC 5.1.1.10 amino-acid racemase
EC 5.1.1.11 phenylalanine racemase (ATP-hydrolysing)
EC 5.1.1.12 ornithine racemase
EC 5.1.1.13 aspartate racemase
EC 5.1.1.14 nocardicin-A epimerase
EC 5.1.1.15 2-aminohexano-6-lactam racemase
EC 5.1.1.16 protein-serine epimerase
EC 5.1.1.17 isopenicillin-N epimerase
EC 5.1.1.18 serine racemase
EC 5.1.2 Acting on Hydroxy Acids and Derivatives
EC 5.1.2.1 lactate racemase
EC 5.1.2.2 mandelate racemase
EC 5.1.2.3 3-hydroxybutyryl-CoA epimerase
EC 5.1.2.4 acetoin racemase
EC 5.1.2.5 tartrate epimerase
EC 5.1.2.6 isocitrate epimerase
EC 5.1.3 Acting on Carbohydrates and Derivatives
EC 5.1.3.1 ribulose-phosphate 3-epimerase
EC 5.1.3.2 UDP-glucose 4-epimerase
EC 5.1.3.3 aldose 1-epimerase
EC 5.1.3.4 L-ribulose-5-phosphate 4-epimerase
EC 5.1.3.5 UDP-arabinose 4-epimerase
EC 5.1.3.6 UDP-glucuronate 4-epimerase
EC 5.1.3.7 UDP-N-acetylglucosamine 4-epimerase
EC 5.1.3.8 N-acylglucosamine 2-epimerase
EC 5.1.3.9 N-acylglucosamine-6-phosphate 2-epimerase
EC 5.1.3.10 CDP-paratose 2-epimerase
EC 5.1.3.11 cellobiose epimerase
EC 5.1.3.12 UDP-glucuronate 5'-epimerase
EC 5.1.3.13 dTDP-4-dehydrorhamnose 3,5-epimerase
EC 5.1.3.14 UDP-N-acetylglucosamine 2-epimerase
EC 5.1.3.15 glucose-6-phosphate 1-epimerase
EC 5.1.3.16 UDP-glucosamine 4-epimerase
EC 5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase
EC 5.1.3.18 GDP-mannose 3,5-epimerase
EC 5.1.3.19 chondroitin-glucuronate 5-epimerase
EC 5.1.3.20 ADP-glyceromanno-heptose 6-epimerase
EC 5.1.3.21 maltose epimerase
EC 5.1.3.22 L-ribulose-5-phosphate 3-epimerase
EC 5.1.3.23 UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase
EC 5.1.99 Acting on Other Compounds
EC 5.1.99.1 methylmalonyl-CoA epimerase
EC 5.1.99.2 16-hydroxysteroid epimerase
EC 5.1.99.3 allantoin racemase
EC 5.1.99.4 α-methylacyl-CoA racemase
EC 5.1.99.5 hydantoin racemase
EC 5.2 cis-trans-Isomerases
EC 5.2.1 (only sub-subclass identified to date)
EC 5.2.1.1 maleate isomerase
EC 5.2.1.2 maleylacetoacetate isomerase
EC 5.2.1.3 retinal isomerase
EC 5.2.1.4 maleylpyruvate isomerase
EC 5.2.1.5 linoleate isomerase
EC 5.2.1.6 furylfuramide isomerase
EC 5.2.1.7 retinol isomerase
EC 5.2.1.8 peptidylprolyl isomerase
EC 5.2.1.9 farnesol 2-isomerase
EC 5.2.1.10 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
EC 5.2.1.11 deleted entry
EC 5.3 Intramolecular isomerases
EC 5.3.1 Interconverting Aldoses and Ketoses
EC 5.3.1.1 triose-phosphate isomerase
EC 5.3.1.2 deleted
EC 5.3.1.3 arabinose isomerase
EC 5.3.1.4 L-arabinose isomerase
EC 5.3.1.5 xylose isomerase
EC 5.3.1.6 ribose-5-phosphate isomerase
EC 5.3.1.7 mannose isomerase
EC 5.3.1.8 mannose-6-phosphate isomerase
EC 5.3.1.9 glucose-6-phosphate isomerase
EC 5.3.1.10 now EC 3.5.99.6
EC 5.3.1.11 deleted
EC 5.3.1.12 glucuronate isomerase
EC 5.3.1.13 arabinose-5-phosphate isomerase
EC 5.3.1.14 L-rhamnose isomerase
EC 5.3.1.15 D-lyxose ketol-isomerase
EC 5.3.1.16 1-(5-phosphoribosyl)-5-[(5-
phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
EC 5.3.1.17 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
EC 5.3.1.18 deleted
EC 5.3.1.19 now EC 2.6.1.16
EC 5.3.1.20 ribose isomerase
EC 5.3.1.21 corticosteroid side-chain-isomerase
EC 5.3.1.22 hydroxypyruvate isomerase
EC 5.3.1.23 5-methylthioribose-1-phosphate isomerase
EC 5.3.1.24 phosphoribosylanthranilate isomerase
EC 5.3.1.25 L-fucose isomerase
EC 5.3.1.26 galactose-6-phosphate isomerase
EC 5.3.1.27 6-phospho-3-hexuloisomerase
EC 5.3.2 Interconverting Keto- and Enol-Groups
EC 5.3.2.1 phenylpyruvate tautomerase
EC 5.3.2.2 oxaloacetate tautomerase
EC 5.3.3 Transposing C=C Bonds
EC 5.3.3.1 steroid Δ-isomerase
EC 5.3.3.2 isopentenyl-diphosphate Δ-isomerase
EC 5.3.3.3 vinylacetyl-CoA Δ-isomerase
EC 5.3.3.4 muconolactone Δ-isomerase
EC 5.3.3.5 cholestenol Δ-isomerase
EC 5.3.3.6 methylitaconate Δ-isomerase
EC 5.3.3.7 aconitate Δ-isomerase
EC 5.3.3.8 dodecenoyl-CoA Δ-isomerase
EC 5.3.3.9 prostaglandin-A1 Δ-isomerase
EC 5.3.3.10 5-carboxymethyl-2-hydroxymuconate Δ-isomerase
EC 5.3.3.11 isopiperitenone Δ-isomerase
EC 5.3.3.12 L-dopachrome isomerase
EC 5.3.3.13 polyenoic fatty acid isomerase
EC 5.3.3.14 trans-2-decenoyl-[acyl-carrier protein] isomerase
EC 5.3.3.15 ascopyrone tautomerase
EC 5.3.4 Transposing S-S Bonds
EC 5.3.4.1 protein disulfide-isomerase
EC 5.3.99 Other Intramolecular Oxidoreductases
EC 5.3.99.1 deleted
EC 5.3.99.2 prostaglandin-D synthase
EC 5.3.99.3 prostaglandin-E synthase
EC 5.3.99.4 prostaglandin-I synthase
EC 5.3.99.5 thromboxane-A synthase
EC 5.3.99.6 allene-oxide cyclase
EC 5.3.99.7 styrene-oxide isomerase
EC 5.3.99.8 capsanthin/capsorubin synthase
EC 5.3.99.9 neoxanthin synthase
EC 5.4 Intramolecular transferases (mutases)
EC 5.4.1 Transferring Acyl Groups
EC 5.4.1.1 lysolecithin acylmutase
EC 5.4.1.2 precorrin-8X methylmutase
EC 5.4.2 Phosphotransferases (Phosphomutases)
EC 5.4.2.1 phosphoglycerate mutase
EC 5.4.2.2 phosphoglucomutase
EC 5.4.2.3 phosphoacetylglucosamine mutase
EC 5.4.2.4 bisphosphoglycerate mutase
EC 5.4.2.5 phosphoglucomutase (glucose-cofactor)
EC 5.4.2.6 β-phosphoglucomutase
EC 5.4.2.7 phosphopentomutase
EC 5.4.2.8 phosphomannomutase
EC 5.4.2.9 phosphoenolpyruvate mutase
EC 5.4.2.10phosphoglucosamine mutase
EC 5.4.3 Transferring Amino Groups
EC 5.4.3.1 deleted
EC 5.4.3.2 lysine 2,3-aminomutase
EC 5.4.3.3 β-lysine 5,6-aminomutase
EC 5.4.3.4 D-lysine 5,6-aminomutase
EC 5.4.3.5 D-ornithine 4,5-aminomutase
EC 5.4.3.6 tyrosine 2,3-aminomutase
EC 5.4.3.7 leucine 2,3-aminomutase
EC 5.4.3.8 glutamate-1-semialdehyde 2,1-aminomutase
EC 5.4.4 Transferring Hydroxy Groups
EC 5.4.4.1 (hydroxyamino)benzene mutase
EC 5.4.4.2 isochorismate synthase
EC 5.4.4.3 3-(hydroxyamino)phenol mutase
EC 5.4.99 Transferring Other Groups
EC 5.4.99.1 methylaspartate mutase
EC 5.4.99.2 methylmalonyl-CoA mutase
EC 5.4.99.3 2-acetolactate mutase
EC 5.4.99.4 2-methyleneglutarate mutase
EC 5.4.99.5 chorismate mutase
EC 5.4.99.6 now EC 5.4.4.2
EC 5.4.99.7 lanosterol synthase
EC 5.4.99.8 cycloartenol synthase
EC 5.4.99.9 UDP-galactopyranose mutase
EC 5.4.99.10 deleted, included in EC 5.4.99.11
EC 5.4.99.11 isomaltulose synthase
EC 5.4.99.12 tRNA-pseudouridine synthase I
EC 5.4.99.13 isobutyryl-CoA mutase
EC 5.4.99.14 4-carboxymethyl-4-methylbutenolide mutase
EC 5.4.99.15 (1 4)-α-D-glucan 1-α-D-glucosylmutase
EC 5.4.99.16 maltose α-D-glucosyltransferase
EC 5.4.99.17 squalene—hopene cyclase
EC 5.4.99.18 5-(carboxyamino)imidazole ribonucleotide mutase
EC 5.5 Intramolecular lyases
EC 5.5.1 (only sub-subclass identified to date)
EC 5.5.1.1 muconate cycloisomerase
EC 5.5.1.2 3-carboxy-cis,cis-muconate cycloisomerase
EC 5.5.1.3 tetrahydroxypteridine cycloisomerase
EC 5.5.1.4 inositol-3-phosphate synthase
EC 5.5.1.5 carboxy-cis,cis-muconate cyclase
EC 5.5.1.6 chalcone isomerase
EC 5.5.1.7 chloromuconate cycloisomerase
EC 5.5.1.8 bornyl diphosphate synthase
EC 5.5.1.9 cycloeucalenol cycloisomerase
EC 5.5.1.10 α-pinene-oxide decyclase
EC 5.5.1.11 dichloromuconate cycloisomerase
EC 5.5.1.12 copalyl diphosphate synthase
EC 5.5.1.13 ent-copalyl diphosphate synthase
EC 5.5.1.14 syn-copalyl diphosphate synthase
EC 5.5.1.15 terpentedienyl-diphosphate synthase
EC 5.5.1.16 halimadienyl-diphosphate synthase
EC 5.99 Other isomerases
EC 5.99.1 Sole sub-subclass for isomerases that do not belong in the other subclasses
EC 5.99.1.1 thiocyanate isomerase
EC 5.99.1.2 DNA topoisomerase
EC 5.99.1.3 DNA topoisomerase (ATP-hydrolysing)
EC 6 Ligases
Enzim yang mengkatalisis penggabungan 2 senyawa diikuti oleh pemecahan ikatan pirofosfat
pada ATP atau senyawa yang sejenis.

EC 6.1 Forming carbon—oxygen bonds


EC 6.1.1 Ligases Forming Aminoacyl-tRNA and Related Compounds
EC 6.1.1.1 tyrosine—tRNA ligase
EC 6.1.1.2 tryptophan—tRNA ligase
EC 6.1.1.3 threonine—tRNA ligase
EC 6.1.1.4 leucine—tRNA ligase
EC 6.1.1.5 isoleucine—tRNA ligase
EC 6.1.1.6 lysine—tRNA ligase
EC 6.1.1.7 alanine—tRNA ligase
EC 6.1.1.8 deleted
EC 6.1.1.9 valine—tRNA ligase
EC 6.1.1.10 methionine—tRNA ligase
EC 6.1.1.11 serine—tRNA ligase
EC 6.1.1.12 aspartate—tRNA ligase
EC 6.1.1.13 D-alanine—poly(phosphoribitol) ligase
EC 6.1.1.14 glycine—tRNA ligase
EC 6.1.1.15 proline—tRNA ligase
EC 6.1.1.16 cysteine—tRNA ligase
EC 6.1.1.17 glutamate—tRNA ligase
EC 6.1.1.18 glutamine—tRNA ligase
EC 6.1.1.19 arginine—tRNA ligase
EC 6.1.1.20 phenylalanine—tRNA ligase
EC 6.1.1.21 histidine—tRNA ligase
EC 6.1.1.22 asparagine—tRNA ligase
EC 6.1.1.23 aspartate—tRNAAsn ligase
EC 6.1.1.24 glutamate—tRNAGln ligase
EC 6.1.1.25 lysine—tRNAPyl ligase
EC 6.1.1.26 pyrrolysine—tRNAPyl ligase
EC 6.1.1.27 O-phosphoserine—tRNA ligase
EC 6.2 Forming carbon—sulfur bonds
EC 6.2.1 Acid—Thiol Ligases
EC 6.2.1.1 acetate—CoA ligase
EC 6.2.1.2 butyrate—CoA ligase
EC 6.2.1.3 long-chain-fatty-acid—CoA ligase
EC 6.2.1.4 succinate—CoA ligase (GDP-forming)
EC 6.2.1.5 succinate—CoA ligase (ADP-forming)
EC 6.2.1.6 glutarate—CoA ligase
EC 6.2.1.7 cholate—CoA ligase
EC 6.2.1.8 oxalate—CoA ligase
EC 6.2.1.9 malate—CoA ligase
EC 6.2.1.10 acid—CoA ligase (GDP-forming)
EC 6.2.1.11 biotin—CoA ligase
EC 6.2.1.12 4-coumarate—CoA ligase
EC 6.2.1.13 acetate—CoA ligase (ADP-forming)
EC 6.2.1.14 6-carboxyhexanoate—CoA ligase
EC 6.2.1.15 arachidonate—CoA ligase
EC 6.2.1.16 acetoacetate—CoA ligase
EC 6.2.1.17 propionate—CoA ligase
EC 6.2.1.18 citrate—CoA ligase
EC 6.2.1.19 long-chain-fatty-acid—luciferin-component ligase
EC 6.2.1.20 long-chain-fatty-acid—[acyl-carrier-protein] ligase
EC 6.2.1.21 covered by EC 6.2.1.30
EC 6.2.1.22 [citrate (pro-3S)-lyase] ligase
EC 6.2.1.23 dicarboxylate—CoA ligase
EC 6.2.1.24 phytanate—CoA ligase
EC 6.2.1.25 benzoate—CoA ligase
EC 6.2.1.26 o-succinylbenzoate—CoA ligase
EC 6.2.1.27 4-hydroxybenzoate—CoA ligase
EC 6.2.1.28 3α,7α-dihydroxy-5β-cholestanate—CoA ligase
EC 6.2.1.29 deleted now EC 6.2.1.7
EC 6.2.1.30 phenylacetate—CoA ligase
EC 6.2.1.31 2-furoate—CoA ligase
EC 6.2.1.32 anthranilate—CoA ligase
EC 6.2.1.33 4-chlorobenzoate—CoA ligase
EC 6.2.1.34 trans-feruloyl-CoA synthase
EC 6.2.1.35 ACP-SH:acetate ligase
EC 6.2.1.36 3-hydroxypropionyl-CoA synthase
EC 6.3 Forming carbon—nitrogen bonds
EC 6.3.1 Acid—Ammonia (or Amine) Ligases (Amide Synthases)
EC 6.3.1.1 aspartate—ammonia ligase
EC 6.3.1.2 glutamate—ammonia ligase
EC 6.3.1.3 now EC 6.3.4.13
EC 6.3.1.4 aspartate—ammonia ligase (ADP-forming)
EC 6.3.1.5 NAD+ synthase
EC 6.3.1.6 glutamate—ethylamine ligase
EC 6.3.1.7 4-methyleneglutamate—ammonia ligase
EC 6.3.1.8 glutathionylspermidine synthase
EC 6.3.1.9 trypanothione synthase
EC 6.3.1.10 adenosylcobinamide-phosphate synthase
EC 6.3.1.11 glutamate—putrescine ligase
EC 6.3.1.12 D-aspartate ligase)
EC 6.3.1.13 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-α-D-glucopyranoside
ligase
EC 6.3.2 Acid—Amino-Acid Ligases (Peptide Synthases)
EC 6.3.2.1 pantoate—β-alanine ligase
EC 6.3.2.2 glutamate—cysteine ligase
EC 6.3.2.3 glutathione synthase
EC 6.3.2.4 D-alanine—D-alanine ligase
EC 6.3.2.5 phosphopantothenate—cysteine ligase
EC 6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase
EC 6.3.2.7 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—L-lysine ligase
EC 6.3.2.8 UDP-N-acetylmuramate—L-alanine ligase
EC 6.3.2.9 UDP-N-acetylmuramoylalanine—D-glutamate ligase
EC 6.3.2.10 UDP-N-acetylmuramoylalanyl-tripeptide—D-alanyl-D-alanine ligase
EC 6.3.2.11 carnosine synthase
EC 6.3.2.12 dihydrofolate synthase
EC 6.3.2.13 UDP-N-acetylmuramoylalanyl-D-glutamate—2,6-diaminopimelate
ligase
EC 6.3.2.14 2,3-dihydroxybenzoate—serine ligase
EC 6.3.2.15 deleted, due to EC 6.3.2.10
EC 6.3.2.16 D-alanine—alanyl-poly(glycerolphosphate) ligase
EC 6.3.2.17 tetrahydrofolate synthase
EC 6.3.2.18 γ-glutamylhistamine synthase
EC 6.3.2.19 ubiquitin—protein ligase
EC 6.3.2.20 indoleacetate—lysine synthetase
EC 6.3.2.21 ubiquitin—calmodulin ligase
EC 6.3.2.22 diphthine—ammonia ligase
EC 6.3.2.23 homoglutathione synthase
EC 6.3.2.24 tyrosine—arginine ligase
EC 6.3.2.25 tubulin—tyrosine ligase
EC 6.3.2.26 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
EC 6.3.2.27 aerobactin synthase
EC 6.3.2.28 L-amino-acid α-ligase
EC 6.3.2.29 cyanophycin synthase (L-aspartate-adding)
EC 6.3.2.30 cyanophycin synthase (L-arginine-adding)
EC 6.3.3 Cyclo-Ligases
EC 6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
EC 6.3.3.2 5-formyltetrahydrofolate cyclo-ligase
EC 6.3.3.3 dethiobiotin synthase
EC 6.3.3.4 (carboxyethyl)arginine β-lactam-synthase
EC 6.3.4 Other Carbon-Nitrogen Ligases
EC 6.3.4.1 GMP synthase
EC 6.3.4.2 CTP synthase
EC 6.3.4.3 formate—tetrahydrofolate ligase
EC 6.3.4.4 adenylosuccinate synthase
EC 6.3.4.5 argininosuccinate synthase
EC 6.3.4.6 urea carboxylase
EC 6.3.4.7 ribose-5-phosphate—ammonia ligase
EC 6.3.4.8 imidazoleacetate—phosphoribosyldiphosphate ligase
EC 6.3.4.9 biotin—[methylmalonyl-CoA-carboxytransferase] ligase
EC 6.3.4.10 biotin—[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase
EC 6.3.4.11 biotin—[methylcrotonoyl-CoA-carboxylase] ligase
EC 6.3.4.12 glutamate—methylamine ligase
EC 6.3.4.13 phosphoribosylamine—glycine ligase
EC 6.3.4.14 biotin carboxylase
EC 6.3.4.15 biotin—[acetyl-CoA-carboxylase] ligase
EC 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
EC 6.3.4.17 formate—dihydrofolate ligase
EC 6.3.4.18 5-(carboxyamino)imidazole ribonucleotide synthase
EC 6.3.5 Carbon—Nitrogen Ligases with Glutamine as Amido-N-Donor
EC 6.3.5.1 NAD+ synthase (glutamine-hydrolysing)
EC 6.3.5.2 GMP synthase (glutamine-hydrolysing)
EC 6.3.5.3 phosphoribosylformylglycinamidine synthase
EC 6.3.5.4 asparagine synthase (glutamine-hydrolysing)
EC 6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
EC 6.3.5.6 asparaginyl-tRNA synthase (glutamine-hydrolysing)
EC 6.3.5.7 glutaminyl-tRNA synthase (glutamine-hydrolysing)
EC 6.3.5.8 now EC 2.6.1.85
EC 6.3.5.9 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
EC 6.3.5.10 adenosylcobyric acid synthase (glutamine-hydrolysing)
EC 6.4 Forming carbon—carbon bonds
EC 6.4.1
EC 6.4.1.1 pyruvate carboxylase
EC 6.4.1.2 acetyl-CoA carboxylase
EC 6.4.1.3 propionyl-CoA carboxylase
EC 6.4.1.4 methylcrotonoyl-CoA carboxylase
EC 6.4.1.5 geranoyl-CoA carboxylase
EC 6.4.1.6 acetone carboxylase
EC 6.4.1.7 2-oxoglutarate carboxylase
EC 6.5 Forming phosphoric ester bonds
EC 6.5.1
EC 6.5.1.1 DNA ligase (ATP)
EC 6.5.1.2 DNA ligase (NAD+)
EC 6.5.1.3 RNA ligase (ATP)
EC 6.5.1.4 RNA-3'-phosphate cyclase
EC 6.6 Forming nitrogen—metal bonds
EC 6.6.1 Forming coordination complexes
EC 6.6.1.1 magnesium chelatase
EC 6.6.1.2 cobaltochelatase

Contoh Reaksi-reaksi yang dikatalisis


EC 1. Oxidoreductases

➢ EC 1.1Acting on the CH-OH group of donors


EC 1.1.1 With NAD or NADP as acceptor
Accepted name: alcohol dehydrogenase
Reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+
Other name(s): aldehyde reductase; ADH; alcohol dehydrogenase (NAD);
aliphatic alcohol dehydrogenase; ethanol dehydrogenase; NAD-dependent
alcohol dehydrogenase; NAD-specific aromatic alcohol dehydrogenase;
NADH-alcohol dehydrogenase; NADH-aldehyde dehydrogenase; primary
alcohol dehydrogenase; yeast alcohol dehydrogenase
Systematic name: alcohol:NAD+ oxidoreductase
Comments: A zinc protein. Acts on primary or secondary alcohols or hemi-
acetals; the animal, but not the yeast, enzyme acts also on cyclic secondary
alcohols.
EC 1.1.2 With a cytochrome as acceptor
Accepted name: mannitol dehydrogenase (cytochrome)
Reaction: D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c
Other name(s): polyol dehydrogenase
Systematic name: D-mannitol:ferricytochrome-c 2-oxidoreductase
Comments: Acts on polyols with a D-lyxo configuration, such as D-mannitol
and D-sorbitol.
EC 1.1.3 With oxygen as acceptor
Accepted name: glucose oxidase
Reaction: β-D-glucose + O2 = D-glucono-1,5-lactone + H2O2
Other name(s): glucose oxyhydrase; corylophyline; penatin; glucose
aerodehydrogenase; microcid; β-D-glucose oxidase; D-glucose oxidase; D-
glucose-1-oxidase; β-D-glucose:quinone oxidoreductase; glucose oxyhydrase;
deoxin-1; GOD
Systematic name: β-D-glucose:oxygen 1-oxidoreductase
Comments: A flavoprotein (FAD).
EC 1.1.4 With a disulfide as acceptor
Accepted name: vitamin-K-epoxide reductase (warfarin-sensitive)

Reaction: 2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol =


2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-
dithiothreitol
Systematic name: 2-methyl-3-phytyl-1,4-naphthoquinone:oxidized-
dithiothreitol oxidoreductase
Comments: In the reverse reaction, vitamin K 2,3-epoxide is reduced to
vitamin K and possibly to vitamin K hydroquinone by 1,4-dithiothreitol, which
is oxidized to a disulfide; some other dithiols and 4-butanethiol can also act.
Inhibited strongly by warfarin [cf. EC 1.1.4.2 vitamin-K-epoxide reductase
(warfarin-insensitive)].
EC 1.1.5 With a quinone or similar compound as acceptor
Accepted name: glycerol-3-phosphate dehydrogenase

Reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a


quinol
Glossary: glycerone phosphate = dihydroxyacetone phosphate = 3-hydroxy-2-
oxopropyl phosphate
Other name(s): α-glycerophosphate dehydrogenase; α-glycerophosphate
dehydrogenase (acceptor); anaerobic glycerol-3-phosphate dehydrogenase; DL-
glycerol 3-phosphate oxidase (misleading); FAD-dependent glycerol-3-
phosphate dehydrogenase; FAD-dependent sn-glycerol-3-phosphate
dehydrogenase; FAD-GPDH; FAD-linked glycerol 3-phosphate
dehydrogenase; FAD-linked L-glycerol-3-phosphate dehydrogenase; flavin-
linked glycerol-3-phosphate dehydrogenase; flavoprotein-linked L-glycerol 3-
phosphate dehydrogenase; glycerol 3-phosphate cytochrome c reductase
(misleading); glycerol phosphate dehydrogenase; glycerol phosphate
dehydrogenase (acceptor); glycerol phosphate dehydrogenase (FAD); glycerol-
3-phosphate CoQ reductase; glycerol-3-phosphate dehydrogenase (flavin-
linked); glycerol-3-phosphate:CoQ reductase; glycerophosphate
dehydrogenase; L-3-glycerophosphate-ubiquinone oxidoreductase; L-glycerol-
3-phosphate dehydrogenase (ambiguous); L-glycerophosphate dehydrogenase;
mGPD; mitochondrial glycerol phosphate dehydrogenase; NAD+-independent
glycerol phosphate dehydrogenase; pyridine nucleotide-independent L-glycerol
3-phosphate dehydrogenase; sn-glycerol 3-phosphate oxidase (misleading); sn-
glycerol-3-phosphate dehydrogenase; sn-glycerol-3-phosphate:(acceptor) 2-
oxidoreductase; sn-glycerol-3-phosphate:acceptor 2-oxidoreductase
Systematic name: sn-glycerol 3-phosphate:quinone oxidoreductase
Comments: This flavin-dependent dehydrogenase is an essential membrane
enzyme, functioning at the central junction of glycolysis, respiration and
phospholipid biosynthesis. In bacteria, the enzyme is localized to the
cytoplasmic membrane [6], while in eukaryotes it is tightly bound to the outer
surface of the inner mitochondrial membrane [2]. In eukaryotes, this enzyme,
together with the cytosolic enzyme EC 1.1.1.8, glycerol-3-phosphate
dehydrogenase (NAD+), forms the glycerol-3-phosphate shuttle by which
NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to
NAD+ by the mitochondrial electron-transport chain [3]. This shuttle plays a
critical role in transferring reducing equivalents from cytosolic NADH into the
mitochondrial matrix [7,8]. Insect flight muscle uses only CoQ10 as the
physiological quinone whereas hamster and rat mitochondria use mainly CoQ9
[4]. The enzyme is activated by calcium [3].
EC 1.1.99 With other acceptors
Accepted name: choline dehydrogenase

Reaction: choline + acceptor = betaine aldehyde + reduced acceptor


Glossary: betaine aldehyde = N,N,N-trimethyl-2-oxoethylammonium
choline = (2-hydroxyethyl)trimethylammonium
Other name(s): choline oxidase; choline-cytochrome c reductase; choline:
(acceptor) oxidoreductase; choline:(acceptor) 1-oxidoreductase
Systematic name: choline:acceptor 1-oxidoreductase
Comments: A quinoprotein. In many bacteria, plants and animals, the
osmoprotectant betaine is synthesized using different enzymes to catalyse the
conversion of (1) choline into betaine aldehyde and (2) betaine aldehyde into
betaine. In plants, the first reaction is catalysed by EC 1.14.15.7, choline
monooxygenase, whereas in animals and many bacteria, it is catalysed by either
membrane-bound choline dehydrogenase (EC 1.1.99.1) or soluble choline
oxidase (EC 1.1.3.17) [4]. The enzyme involved in the second step, EC 1.2.1.8,
betaine-aldehyde dehydrogenase, appears to be the same in plants, animals and
bacteria.

➢ EC 1.2Acting on the aldehyde or oxo group of donors

EC 1.2.1 With NAD or NADP as acceptor


Accepted name: aldehyde dehydrogenase (NAD)
Reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+
Other name(s): CoA-independent aldehyde dehydrogenase; m-
methylbenzaldehyde dehydrogenase; NAD-aldehyde dehydrogenase; NAD-
dependent 4-hydroxynonenal dehydrogenase; NAD-dependent aldehyde
dehydrogenase; NAD-linked aldehyde dehydrogenase; propionaldehyde
dehydrogenase; aldehyde dehydrogenase (NAD)
Systematic name: aldehyde:NAD+ oxidoreductase
Comments: Wide specificity, including oxidation of D-glucuronolactone to D-
glucarate. Formerly EC 1.1.1.70.
EC 1.2.2 With a cytochrome as acceptor
Accepted name: formate dehydrogenase (cytochrome)
Reaction: formate + 2 ferricytochrome b1 = CO2 + 2 ferrocytochrome b1 + 2 H+
Other name(s): formate dehydrogenase; formate:cytochrome b1
oxidoreductase
Systematic name: formate:ferricytochrome-b1 oxidoreductase
EC 1.2.3 With oxygen as acceptor
Accepted name: glyoxylate oxidase
Reaction: glyoxylate + H2O + O2 = oxalate + H2O2
Systematic name: glyoxylate:oxygen oxidoreductase
EC 1.2.4 With a disulfide as acceptor
Accepted name: pyruvate dehydrogenase (acetyl-transferring)
Reaction: pyruvate + [dihydrolipoyllysine-residue acetyltransferase]
lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-
acetyldihydrolipoyllysine + CO2

Oxo-acid dehydrogenase complexes


© IUBMB 2003

Note 1: The acyl group on the dihydrolipoyl group of EC 2.3.1.12 moves rapidly between S-8
and S-6, with more on S-8 at equilibrium.

Note 2: E1 (EC 1.2.4.1, EC 1.2.4.2 or EC 1.2.4.4) contains thiamine diphosphate

The N6-lipoyllysine residues of E2 (EC 2.3.1.12, EC 2.3.1.61 and EC 2.3.1.168) are the
substrates reductively acylated by EC 1.2.4.1, EC 1.2.4.2, and EC 1.2.4.4 respectively.

The overall reaction is:


R-CO-COO- + NAD+ + HS-CoA = R-CO-S-CoA + NADH + CO2
Other name(s): MtPDC (mitochondrial pyruvate dehydogenase complex);
pyruvate decarboxylase; pyruvate dehydrogenase; pyruvate dehydrogenase
(lipoamide); pyruvate dehydrogenase complex; pyruvate:lipoamide 2-
oxidoreductase (decarboxylating and acceptor-acetylating); pyruvic acid
dehydrogenase; pyruvic dehydrogenase
Systematic name: pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-
lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)
Comments: Contains thiamine diphosphate. It is a component (in multiple
copies) of the multienzyme pyruvate dehydrogenase complex in which it is
bound to a core of molecules of EC 2.3.1.12, dihydrolipoyllysine-residue
acetyltransferase, which also binds multiple copies of EC 1.8.1.4, dihydrolipoyl
dehydrogenase. It does not act on free lipoamide or lipoyllysine, but only on
the lipoyllysine residue in EC 2.3.1.12.
EC 1.2.7 With an iron-sulfur protein as acceptor
Accepted name: pyruvate synthase

Reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2


reduced ferredoxin + 2 H+
Other name(s): pyruvate oxidoreductase; pyruvate synthetase;
pyruvate:ferredoxin oxidoreductase; pyruvic-ferredoxin oxidoreductase
Systematic name: pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)
Comments: Contains thiamine diphosphate and [4Fe-4S] clusters. This
enzyme is one of four 2-oxoacid oxidoreductases that are differentiated by their
abilities to oxidatively decarboxylate different 2-oxoacids and form their CoA
derivatives [see also EC 1.2.7.3, 2-oxoglutarate synthase, EC 1.2.7.7, 3-methyl-
2-oxobutanoate dehydrogenase (ferredoxin) and EC 1.2.7.8, indolepyruvate
ferredoxin oxidoreductase].
EC 1.2.99 With other acceptors
Accepted name: carbon-monoxide dehydrogenase (acceptor)

Reaction: CO + H2O + A = CO2 + AH2


Other name(s): anaerobic carbon monoxide dehydrogenase; carbon monoxide
oxygenase; carbon-monoxide dehydrogenase; carbon-monoxide:(acceptor)
oxidoreductase
Systematic name: carbon-monoxide:acceptor oxidoreductase
Comments: Contains a [Ni3Fe-4S] cluster and [4Fe-4S] clusters. It uses many
electron acceptors, including ferredoxin, methyl viologen and benzyl viologen
and flavins, but not pyridine nucleotides. Forms part of a membrane-bound
multienzyme complex with EC 1.12.99.6, hydrogenase (acceptor), which
catalyses the overall reaction: CO + H2O = CO2 + H2.
➢ EC 1.3Acting on the CH-CH group of donors
EC 1.3.1 With NAD or NADP as acceptor
Accepted name: dihydrouracil dehydrogenase (NAD+)
Reaction: 5,6-dihydrouracil + NAD+ = uracil + NADH + H+
Other name(s): dehydrogenase, dihydrouracil; dihydropyrimidine
dehydrogenase; dihydrothymine dehydrogenase; pyrimidine reductase; thymine
reductase; uracil reductase; dihydrouracil dehydrogenase (NAD)
Systematic name: 5,6-dihydrouracil:NAD+ oxidoreductase
EC 1.3.2 With a cytochrome as acceptor
Accepted name: L-galactonolactone dehydrogenase

Reaction: (1) L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2


ferrocytochrome c + 2 H+
(2) L-ascorbate + 2 ferricytochrome c = L-dehydroascorbate + 2
ferrocytochrome c + 2 H+ (spontaneous)
Other name(s): galactonolactone dehydrogenase; L-galactono-γ-lactone
dehydrogenase; L-galactono-γ-lactone:ferricytochrome-c oxidoreductase;
GLDHase; GLDase
Systematic name: L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase
Comments: This enzyme catalyses the final step in the biosynthesis of L-
ascorbic acid in higher plants and in nearly all higher animals with the
exception of primates and some birds [5]. The enzyme is very specific for its
substrate L-galactono-1,4-lactone as D-galactono-γ-lactone, D-gulono-γ-
lactone, L-gulono-γ-lactone, D-erythronic-γ-lactone, D-xylonic-γ-lactone, L-
mannono-γ-lactone, D-galactonate, D-glucuronate and D-gluconate are not
substrates [5]. FAD, NAD+, NADP+ and O2 (cf. EC 1.3.3.12, L-
galactonolactone oxidase) cannot act as electron acceptor [5].
EC 1.3.3 With oxygen as acceptor
Accepted name: dihydroorotate oxidase

Reaction: (S)-dihydroorotate + O2 = orotate + H2O2


Other name(s): DHOdehase; dihydroorotate dehydrogenase (ambiguous);
dihydoorotic acid dehydrogenase; (DHO) dehydrogenase; 4,5-L-
dihydroorotate:oxygen oxidoreductase
Systematic name: (S)-dihydroorotate:oxygen oxidoreductase
Comments: A flavoprotein (FAD, FMN). Ferricyanide can act as acceptor.
EC 1.3.5 With a quinone or related compound as acceptor
Accepted name: dihydroorotate dehydrogenase
Reaction: (S)-dihydroorotate + a quinone = orotate + a quinol
Other name(s): dihydroorotate:ubiquinone oxidoreductase; (S)-dihydroorotate:
(acceptor) oxidoreductase; (S)-dihydroorotate:acceptor oxidoreductase;
DHODH; DHOD; DHOdehase
Systematic name: (S)-dihydroorotate:quinone oxidoreductase
Comments: This Class 2 dihydroorotate dehydrogenase enzyme contains
flavin [4]. The reaction, which takes place in the mitochondrial membrane, is
the only redox reaction in the de-novo biosynthesis of pyrimidine nucleotides
[2,4]. The best quinone electron acceptors for the enzyme from bovine liver are
coenzymes Q6 and Q7, although simple quinones, such as benzoquinone, can
also act as acceptor but at lower rates [2]. Methyl-, ethyl-, tert-butyl and
benzyl-(S)-dihydroorotates are also substrates, but 1- and 3-methyl and 1,3-
dimethyl methyl-(S)-dihydroorotates are not [2].
EC 1.3.7 With an iron-sulfur protein as acceptor
Accepted name: 6-hydroxynicotinate reductase

Reaction: 6-oxo-1,4,5,6-tetrahydronicotinate + oxidized ferredoxin = 6-


hydroxynicotinate + reduced ferredoxin
Other name(s): 6-oxotetrahydronicotinate dehydrogenase; 6-hydroxynicotinic
reductase; HNA reductase
Systematic name: 6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin
oxidoreductase
EC 1.3.99 With other acceptors
Accepted name: succinate dehydrogenase

Reaction: succinate + acceptor = fumarate + reduced acceptor


Other name(s): succinic dehydrogenase; fumarate reductase; fumaric
hydrogenase; succinodehydrogenase; succinic acid dehydrogenase; succinate
oxidoreductase; succinyl dehydrogenase; succinate:(acceptor) oxidoreductase
Systematic name: succinate:acceptor oxidoreductase
Comments: A flavoprotein (FAD) containing iron-sulfur centres. A component
of EC 1.3.5.1 succinate dehydrogenase (ubiquinone).
➢ EC 1.4Acting on the CH-NH2 group of donors

EC 1.4.1 With NAD or NADP as acceptor


Accepted name: alanine dehydrogenase
Reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+
Other name(s): AlaDH; L-alanine dehydrogenase; NAD-linked alanine
dehydrogenase; α-alanine dehydrogenase; NAD-dependent alanine
dehydrogenase; alanine oxidoreductase; NADH-dependent alanine
dehydrogenase
Systematic name: L-alanine:NAD+ oxidoreductase (deaminating)
EC 1.4.2 With a cytochrome as acceptor
Accepted name: glycine dehydrogenase (cytochrome)
Reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2
ferrocytochrome c + 2 H+
Other name(s): glycine—cytochrome c reductase
Systematic name: glycine:ferricytochrome-c oxidoreductase (deaminating)
EC 1.4.3 With oxygen as acceptor
Accepted name: D-aspartate oxidase
Reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2
Other name(s): aspartic oxidase; D-aspartic oxidase
Systematic name: D-aspartate:oxygen oxidoreductase (deaminating)
Comments: A flavoprotein (FAD).
EC 1.4.4 With a disulfide as acceptor
Accepted name: glycine dehydrogenase (decarboxylating)

Reaction: glycine + H-protein-lipoyllysine = H-protein-S-


aminomethyldihydrolipoyllysine + CO2
Glycine Cleavage System

© IUBMB 2003
The diagram shows how the lipoyl group of the H protein can visit the three
enzymes of the multienzyme system of EC 1.4.4.2 glycine dehydrogenase
(decarboxylating), EC 1.8.1.4 dihydrolipoyl dehydrogenase and EC 2.1.2.10
aminomethyltransferase, being transformed by each.
Other name(s): P-protein; glycine decarboxylase; glycine-cleavage complex;
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-
aminomethylating); protein P1
Systematic name: glycine:H-protein-lipoyllysine oxidoreductase
(decarboxylating, acceptor-amino-methylating)
Comments: A pyridoxal-phosphate protein. A component, with EC 2.1.2.10,
aminomethyltransferase and EC 1.8.1.4, dihydrolipoyl dehydrogenanse, of the
glycine cleavage system, previously known as glycine synthase. The glycine
cleavage system is composed of four components that only loosely associate:
the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC
1.8.1.4) and the lipoyl-bearing H protein [3].
EC 1.4.7 With an iron-sulfur protein as acceptor
Accepted name: glutamate synthase (ferredoxin)
Reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-
oxoglutarate + 2 reduced ferredoxin + 2 H+
Other name(s): ferredoxin-dependent glutamate synthase; ferredoxin-
glutamate synthase; glutamate synthase (ferredoxin-dependent)
Systematic name: L-glutamate:ferredoxin oxidoreductase (transaminating)
Comments: An iron-sulfur flavoprotein.
EC 1.4.99 With other acceptors
Accepted name: D-amino-acid dehydrogenase
Reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced
acceptor
Other name(s): D-amino-acid:(acceptor) oxidoreductase (deaminating)
Systematic name: D-amino-acid:acceptor oxidoreductase (deaminating)
Comments: A flavoprotein (FAD). Acts to some extent on all D-amino acids,
except D-aspartate and D-glutamate.
EC 2 Transferases
➢ EC 2.1Transferring one-carbon groups
EC 2.1.1 Methyltransferases
Accepted name: nicotinamide N-methyltransferase
Reaction: S-adenosyl-L-methionine + nicotinamide = S-adenosyl-L-homocysteine + 1-
methylnicotinamide
Other name(s): nicotinamide methyltransferase
Systematic name: S-adenosyl-L-methionine:nicotinamide N-methyltransferase
➢ EC 2.2Transferring aldehyde or ketonic groups
EC 2.2.1 Transketolases and Transaldolases
Accepted name: transketolase

Reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-


phosphate + D-xylulose 5-phosphate
Transketolase

Mechanism of EC 2.2.1.1 and EC 2.2.1.3


Transketolase
Other name(s): glycolaldehydetransferase
Systematic name: sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate
glycolaldehydetransferase
Comments: A thiamine-diphosphate protein. Wide specificity for both reactants, e.g. converts
hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH. Transketolase from
Alkaligenes faecalis shows high activity with D-erythrose as acceptor.

➢ EC 2.3Acyltransferases
EC 2.3.2 Aminoacyltransferases
Accepted name: D-glutamyltransferase
Reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-
peptide
Other name(s): D-glutamyl transpeptidase; D-γ-glutamyl transpeptidase
Systematic name: glutamine:D-glutamyl-peptide 5-glutamyltransferase
➢ EC 2.4Glycosyltransferases
EC 2.4.1 Hexosyltransferases
Accepted name: amylosucrase
Reaction: sucrose + [(1→4)-α-D-glucosyl]n = D-fructose + [(1→4)-α-D-glucosyl]n+1
Other name(s): sucrose—glucan glucosyltransferase; sucrose-1,4-α-glucan
glucosyltransferase; sucrose:1,4-α-D-glucan 4-α-D-glucosyltransferase
Systematic name: sucrose:(1→4)-α-D-glucan 4-α-D-glucosyltransferase
➢ EC 2.5Transferring alkyl or aryl groups, other than methyl groups
EC 2.5.1 Transferring Alkyl or Aryl Groups, Other than Methyl Groups
Accepted name: galactose-6-sulfurylase

Reaction: Eliminates sulfate from the D-galactose 6-sulfate residues of porphyran,


producing 3,6-anhydrogalactose residues
Other name(s): porphyran sulfatase; galactose-6-sulfatase; galactose 6-sulfatase
Systematic name: D-galactose-6-sulfate:alkyltransferase (cyclizing)
➢ EC 2.6Transferring nitrogenous groups
EC 2.6.1 Transaminases
Accepted name: cysteine transaminase

Reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate


Other name(s): cysteine aminotransferase; L-cysteine aminotransferase; CGT
Systematic name: L-cysteine:2-oxoglutarate aminotransferase
➢ EC 2.7Transferring phosphorus-containing groups
EC 2.7.1 Phosphotransferases with an alcohol group as acceptor
Accepted name: hexokinase
Reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate
Other name(s): hexokinase type IV glucokinase; hexokinase D; hexokinase type IV;
hexokinase (phosphorylating); ATP-dependent hexokinase; glucose ATP
phosphotransferase
Systematic name: ATP:D-hexose 6-phosphotransferase
Comments: D-Glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act
as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes
been called glucokinase.
➢ EC 2.8Transferring sulfur-containing groups
EC 2.8.1 Sulfurtransferases
Accepted name: thiosulfate sulfurtransferase
Reaction: thiosulfate + cyanide = sulfite + thiocyanate
Other name(s): thiosulfate cyanide transsulfurase; thiosulfate thiotransferase;
rhodanese; rhodanase
Systematic name: thiosulfate:cyanide sulfurtransferase
Comments: A few other sulfur compounds can act as donors.
EC 2.9Transferring selenium-containing groups
EC 2.9.1 Selenotransferases
Accepted name: L-seryl-tRNASec selenium transferase

Reaction: L-seryl-tRNASec + selenophosphate = L-selenocysteinyl-tRNASec +


phosphate
Other name(s): L-selenocysteinyl-tRNASel synthase; L-selenocysteinyl-tRNASec
synthase selenocysteine synthase; cysteinyl-tRNASec-selenium transferase; cysteinyl-
tRNASec-selenium transferase
Systematic name: selenophosphate:L-seryl-tRNASec selenium transferase
Comments: a pyridoxal 5'-phosphate enzyme identified in Escherichia coli.
Recognises specifically tRNASec-species. Binding of tRNASec also occurs in the
absence of the seryl group. 2-Aminoacryloyl-tRNA, bound to the enzyme as an imine
with the pyridoxal phosphate, is an intermediate in the reaction. Since the selenium
atom replaces oxygen in serine, the product may also be referred to as L-selenoseryl-
tRNASec. The symbol Sel has also been used for selenocysteine but Sec is preferred.

EC 3 Hydrolases
➢ EC 3.1Acting on ester bonds
EC 3.1.1 Carboxylic Ester Hydrolases
Accepted name: carboxylesterase
Reaction: A carboxylic ester + H2O = an alcohol + a carboxylate
Other name(s): ali-esterase; B-esterase; monobutyrase; cocaine esterase; procaine
esterase; methylbutyrase; vitamin A esterase; butyryl esterase; carboxyesterase;
carboxylate esterase; carboxylic esterase; methylbutyrate esterase; triacetin esterase;
carboxyl ester hydrolase; butyrate esterase; methylbutyrase; α-carboxylesterase;
propionyl esterase; nonspecific carboxylesterase; esterase D; esterase B; esterase A;
serine esterase; carboxylic acid esterase; cocaine esterase
Systematic name: carboxylic-ester hydrolase
EC 3.2Glycosylases
➢ EC 3.2.2 Hydrolysing N-Glycosyl Compounds
Accepted name: purine nucleosidase
Reaction: a purine nucleoside + H2O = D-ribose + a purine base
Other name(s): nucleosidase; purine β-ribosidase; purine nucleoside hydrolase; purine
ribonucleosidase; ribonucleoside hydrolase; nucleoside hydrolase; N-ribosyl purine
ribohydrolase; nucleosidase g; N-D-ribosylpurine ribohydrolase; inosine-adenosine-
guanosine preferring nucleoside hydrolase; purine-specific nucleoside N-
ribohydrolase; IAG-nucleoside hydrolase; IAG-NH
Systematic name: purine-nucleoside ribohydrolase
Comments: The enzyme from the bacterium Ochrobactrum anthropi specifically
catalyses the irreversible N-riboside hydrolysis of purine nucleosides. Pyrimidine
nucleosides, purine and pyrimidine nucleotides, NAD+, NADP+ and nicotinaminde
mononucleotide are not substrates [6].
➢ EC 3.3Acting on ether bonds
EC 3.3.2 Ether hydrolases
Accepted name: isochorismatase

Reaction: isochorismate + H2O = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate


Other name(s): 2,3-dihydro-2,3-dihydroxybenzoate synthase; 2,3-dihydroxy-2,3-
dihydrobenzoate synthase; 2,3-dihydroxy-2,3-dihydrobenzoic synthase
Systematic name: isochorismate pyruvate-hydrolase
➢ EC 3.4Acting on peptide bonds (peptidases)
EC 3.4.11 Aminopeptidases
Accepted name: leucyl aminopeptidase

Reaction: Release of an N-terminal amino acid, Xaa Yaa-, in which Xaa is


preferably Leu, but may be other amino acids including Pro although not Arg or Lys,
and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolysed,
but rates on arylamides are exceedingly low
Other names: leucine aminopeptidase; leucyl peptidase; peptidase S; cytosol
aminopeptidase; cathepsin III; L-leucine aminopeptidase; leucinaminopeptidase;
leucinamide aminopeptidase; FTBL proteins; proteinates FTBL; aminopeptidase II;
aminopeptidase III; aminopeptidase I
➢ EC 3.5Acting on carbon-nitrogen bonds, other than peptide bonds
EC 3.5.1 In Linear Amides
Accepted name: asparaginase
Reaction: L-asparagine + H2O = L-aspartate + NH3
Other name(s): asparaginase II; L-asparaginase; colaspase; elspar; leunase; crasnitin;
α-asparaginase
Systematic name: L-asparagine amidohydrolase
➢ EC 3.6Acting on acid anhydrides
EC 3.6.1 In Phosphorus-Containing Anhydrides
Accepted name: inorganic diphosphatase

Reaction: diphosphate + H2O = 2 phosphate


Systematic name: diphosphate phosphohydrolase
Comments: Specificity varies with the source and with the activating metal ion. The
enzyme from some sources may be identical with EC 3.1.3.1 (alkaline phosphatase) or
EC 3.1.3.9 (glucose-6-phosphatase). A form of this enzyme with a molecular mass of
about 90 kDa is found in tonoplasts of plants and fungi, where it imports protons from
the cytosol into the vacuolar lumen.
➢ EC 3.7Acting on carbon-carbon bonds
EC 3.7.1 In Ketonic Substances
Accepted name: oxaloacetase
Reaction: oxaloacetate + H2O = oxalate + acetate
Other name(s):oxalacetic hydrolase
Systematic name: oxaloacetate acetylhydrolase
➢ EC 3.8Acting on halide bonds
EC 3.8.1 In C-Halide Compounds
Accepted name: alkylhalidase
Reaction: bromochloromethane + H2O = formaldehyde + bromide + chloride
Other name(s): halogenase; haloalkane halidohydrolase; haloalkane dehalogenase
Systematic name: alkyl-halide halidohydrolase

➢ EC 3.9Acting on phosphorus-nitrogen bonds


Accepted name: phosphoamidase

Reaction: N-phosphocreatine + H2O = creatine + phosphate


Other name(s): creatine phosphatase
Systematic name: phosphamide hydrolase
Comments: Also acts on N-phospho-arginine and other phosphoamides. Possibly
identical with EC 3.1.3.9 (glucose-6-phosphatase) or EC 3.1.3.16 (phosphoprotein
phosphatase).
➢ EC 3.10Acting on sulfur-nitrogen bonds
Accepted name: cyclamate sulfohydrolase
Reaction: cyclohexylsulfamate + H2O = cyclohexylamine + sulfate
Other name(s): cyclamate sulfamatase; cyclamate sulfamidase; cyclohexylsulfamate
sulfamidase
Systematic name: cyclohexylsulfamate sulfohydrolase
Comments: Also readily hydrolyses aliphatic sulfamates with 3 to 8 carbons.
➢ EC 3.11Acting on carbon-phosphorus bonds
Accepted name: phosphonoacetaldehyde hydrolase
Reaction: phosphonoacetaldehyde + H2O = acetaldehyde + phosphate
Other name(s): phosphonatase; 2-phosphonoacetylaldehyde phosphonohydrolase
Systematic name: 2-oxoethylphosphonate phosphonohydrolas
➢ EC 3.12Acting on sulfur-sulfur bonds
Accepted name: trithionate hydrolase
Reaction: trithionate + H2O = thiosulfate + sulfate + 2 H+
Systematic name: trithionate thiosulfohydrolase

➢ EC 3.13Acting on carbon-sulfur bonds


Accepted name: 2'-hydroxybiphenyl-2-sulfinate desulfinase

Reaction: 2'-hydroxybiphenyl-2-sulfinate + H2O = 2-hydroxybiphenyl + sulfite


Other name(s): gene dszB-encoded hydrolase; 2-(2-hydroxyphenyl)
benzenesulfinate:H2O hydrolase; DszB; HBPSi desulfinase; 2-(2-hydroxyphenyl)
benzenesulfinate sulfohydrolase; HPBS desulfinase; 2-(2-
hydroxyphenyl)benzenesulfinate hydrolase; 2-(2'-hydroxyphenyl)benzenesulfinate
desulfinase; 2-(2-hydroxyphenyl)benzenesulfinate desulfinase
Systematic name: 2'-hydroxybiphenyl-2-sulfinate sulfohydrolase
Comments: The enzyme from Rhodococcus sp. strain IGTS8 is encoded by the
plasmid-encoded dibenzothiophene-desulfurization (dsz) operon. The enzyme has a
narrow substrate specificity with biphenyl-2-sulfinate being the only other substrate
known to date [2].

EC 4 Lyases
➢ EC 4.1Carbon-carbon lyases
EC 4.1.2 Aldehyde-Lyases
Accepted name: ketotetrose-phosphate aldolase
Reaction: erythrulose 1-phosphate = glycerone phosphate + formaldehyde
Other name(s): phosphoketotetrose aldolase; erythrulose-1-phosphate synthetase;
erythrose-1-phosphate synthase; erythrulose-1-phosphate formaldehyde-lyase
Systematic name: erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-
forming)
➢ EC 4.2Carbon-oxygen lyases
EC 4.2.1 Hydro-Lyases
Accepted name: carbonate dehydratase
Reaction: H2CO3 = CO2 + H2O
Other name(s): carbonic anhydrase; anhydrase; carbonate anhydrase; carbonic acid
anhydrase; carboxyanhydrase; carbonic anhydrase A; carbonate hydro-lyase
Systematic name: carbonate hydro-lyase (carbon-dioxide-forming)
Comments: A zinc protein.
➢ EC 4.3Carbon-nitrogen lyases
EC 4.3.1 Ammonia-Lyases
Accepted name: aspartate ammonia-lyase
Reaction: L-aspartate = fumarate + NH3
Other name(s): aspartase; fumaric aminase; L-aspartase; L-aspartate ammonia-lyase
Systematic name: L-aspartate ammonia-lyase (fumarate-forming)
➢ EC 4.4Carbon-sulfur lyases
Accepted name: alliin lyase
Reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate
Other name(s): alliinase; cysteine sulfoxide lyase; alkylcysteine sulfoxide lyase; S-
alkylcysteine sulfoxide lyase; L-cysteine sulfoxide lyase; S-alkyl-L-cysteine sulfoxide
lyase; alliin alkyl-sulfenate-lyase
Systematic name: S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase (2-aminoacrylate-
forming)
Comments: A pyridoxal-phosphate protein.
➢ EC 4.5Carbon-halide lyases
Accepted name: DDT-dehydrochlorinase
Reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-
chlorophenyl)ethylene + chloride
Other name(s): DDT-as; 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase
➢ Systematic name: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-
dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]
EC 4.6Phosphorus-oxygen lyases
Accepted name: adenylate cyclase

Reaction: ATP = 3',5'-cyclic AMP + diphosphate


Other name(s): adenylylcyclase; adenyl cyclase; 3',5'-cyclic AMP synthetase; ATP
diphosphate-lyase (cyclizing)
Systematic name: ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming)
Comments: Also acts on dATP to form 3',5'-cyclic dAMP. Requires pyruvate.
Activated by NAD+ in the presence of EC 2.4.2.31 NAD(P)+—arginine ADP-
ribosyltransferase .
➢ EC 4.99Other lyases
Accepted name: ferrochelatase

Reaction: protoheme + 2 H+ = protoporphyrin + Fe2+


Other name(s): ferro-protoporphyrin chelatase; iron chelatase; heme synthetase; heme
synthase; protoheme ferro-lyase
Systematic name: protoheme ferro-lyase (protoporphyrin-forming)

EC 5Isomerases
➢ EC 5.1Racemases and epimerases
EC 5.1.1 Acting on Amino Acids and Derivatives
Accepted name: alanine racemase
Reaction: L-alanine = D-alanine
Other name(s): L-alanine racemase
Systematic name: alanine racemase
Comments: A pyridoxal-phosphate protein.
➢ EC 5.2cis-trans-Isomerases
Accepted name: maleate isomerase
Reaction: maleate = fumarate
Systematic name: maleate cis-trans-isomerase
➢ EC 5.3Intramolecular isomerases
EC 5.3.1 Interconverting Aldoses and Ketoses
Accepted name: triose-phosphate isomerase

Reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate


For diagram of reaction click here, alternative click here.
Other name(s): phosphotriose isomerase; triose phosphoisomerase; triose phosphate
mutase; D-glyceraldehyde-3-phosphate ketol-isomerase
Systematic name: D-glyceraldehyde-3-phosphate aldose-ketose-isomerase
➢ EC 5.4Intramolecular transferases (mutases)
EC 5.4.1 Transferring Acyl Groups
Accepted name: lysolecithin acylmutase
Reaction: 2-lysolecithin = 3-lysolecithin
Other name(s): lysolecithin migratase
Systematic name: lysolecithin 2,3-acylmutase
➢ EC 5.5Intramolecular lyases
Accepted name: muconate cycloisomerase

Reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate


Other name(s): muconate cycloisomerase I; cis,cis-muconate-lactonizing enzyme;
cis,cis-muconate cycloisomerase; muconate lactonizing enzyme; 4-carboxymethyl-4-
hydroxyisocrotonolactone lyase (decyclizing); CatB; MCI
➢ Systematic name: 2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)
EC 5.99Other isomerases
Accepted name: thiocyanate isomerase
Reaction: benzyl isothiocyanate = benzyl thiocyanate
Other name(s): isothiocyanate isomerase
Systematic name: benzyl-thiocyanate isomerase
EC 6Ligases
➢ EC 6.1Forming carbon—oxygen bonds
EC 6.1.1 Ligases Forming Aminoacyl-tRNA and Related Compounds
Accepted name: tyrosine—tRNA ligase
Reaction: ATP + L-tyrosine + tRNATyr = AMP + diphosphate + L-tyrosyl-tRNATyr
Other name(s): tyrosyl-tRNA synthetase; L-tyrosine-tRNATyr ligase (AMP-forming);
tyrosyl-transfer ribonucleate synthetase; tyrosyl-transfer RNA synthetase; tyrosyl-
transfer ribonucleic acid synthetase; tyrosyl-tRNA ligase; tyrosine-transfer RNA
ligase; tyrosine-transfer ribonucleate synthetase; tyrosine translase; tyrosine tRNA
synthetase
Systematic name: L-tyrosine:tRNATyr ligase (AMP-forming)
➢ EC 6.2Forming carbon—sulfur bonds
EC 6.2.1 Acid—Thiol Ligases
Accepted name: acetate—CoA ligase
Reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
Other name(s): acetyl-CoA synthetase; acetyl activating enzyme; acetate thiokinase;
acyl-activating enzyme; acetyl coenzyme A synthetase; acetic thiokinase; acetyl CoA
ligase; acetyl CoA synthase; acetyl-coenzyme A synthase; short chain fatty acyl-CoA
synthetase; short-chain acyl-coenzyme A synthetase; ACS
Systematic name: acetate:CoA ligase (AMP-forming)
Comments: Also acts on propanoate and propenoate.
➢ EC 6.3Forming carbon—nitrogen bonds
EC 6.3.1 Acid—Ammonia (or Amine) Ligases (Amide Synthases)
Accepted name: aspartate—ammonia ligase
Reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine
Other name(s): asparagine synthetase; L-asparagine synthetase
Systematic name: L-aspartate:ammonia ligase (AMP-forming)
➢ EC 6.4Forming carbon—carbon bonds
Accepted name: pyruvate carboxylase
Reaction: ATP + pyruvate + HCO3- = ADP + phosphate + oxaloacetate
Other name(s): pyruvic carboxylase
Systematic name: pyruvate:carbon-dioxide ligase (ADP-forming)
Comments: A biotinyl-protein containing manganese (animal tissues) or zinc (yeast).
The animal enzyme requires acetyl-CoA.
➢ EC 6.5Forming phosphoric ester bonds
Accepted name: DNA ligase (ATP)
Reaction: ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m = AMP +
diphosphate + (deoxyribonucleotide)n+m
Other name(s): polydeoxyribonucleotide synthase (ATP); polynucleotide ligase;
sealase; DNA repair enzyme; DNA joinase; DNA ligase; deoxyribonucleic ligase;
deoxyribonucleate ligase; DNA-joining enzyme; deoxyribonucleic-joining enzyme;
deoxyribonucleic acid-joining enzyme; deoxyribonucleic repair enzyme;
deoxyribonucleic joinase; deoxyribonucleic acid ligase; deoxyribonucleic acid joinase;
deoxyribonucleic acid repair enzyme
Systematic name: poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase
(AMP-forming)
Comments: Catalyses the formation of a phosphodiester at the site of a single-strand
break in duplex DNA. RNA can also act as substrate, to some extent.
➢ EC 6.6Forming nitrogen—metal bonds
EC 6.6.1 Forming coordination complexes
Accepted name: magnesium chelatase

Reaction: ATP + protoporphyrin IX + Mg2+ + H2O = ADP + phosphate + Mg-


protoporphyrin IX + 2 H+
For diagram of reaction click here (heme and chlorophyll biosynthesis).
Other name(s): protoporphyrin IX magnesium-chelatase; protoporphyrin IX Mg-
chelatase; magnesium-protoporphyrin IX chelatase; magnesium-protoporphyrin
chelatase; magnesium-chelatase; Mg-chelatase; Mg-protoporphyrin IX magnesio-lyase
Systematic name: Mg-protoporphyrin IX magnesium-lyase
Comments: This is the first committed step of chlorophyll biosynthesis and is a
branchpoint of two major routes in the tetrapyrrole pathway.
DAFTAR PUSTAKA

Anonim, 2010. Enzyme Nomenclature; Recommendations of the Nomenclature


Committee of the International Union of Biochemistry and Molecular Biology on the
Nomenclature and Classification of Enzymes by the Reactions they Catalyse
Available at : http://www.chem.qmul.ac.uk/iubmb/enzyme/
Last opened : 23 Mei 2010

Indah, Mutiara. 2010. Enzim. Fakultas Kedokteran Universitas Sumatera Utara. Sumatra
Utara