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  • Megaloblastic Anemia

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    MyNurse Myrna
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    Table 3 summarizes drugs that can interact with oral iron supplementation by either reducing iron absorption, such as antacids, or increasing iron absorption, such as vitamin C. Table 4 lists causes of resistant iron deficiency anemia, including continuing blood loss from menstruation or bleeding, ineffective iron intake due to poor compliance or gastrointestinal side effects, and ineffective iron absorption due to malabsorption states like celiac disease or Crohn's disease.

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    Table 3 summarizes drugs that can interact with oral iron supplementation by either reducing iron absorption, such as antacids, or increasing iron absorption, such as vitamin C. Table 4 lists causes of resistant iron deficiency anemia, including continuing blood loss from menstruation or bleeding, ineffective iron intake due to poor compliance or gastrointestinal side effects, and ineffective iron absorption due to malabsorption states like celiac disease or Crohn's disease.

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    14 tayangan1 halaman

    Megaloblastic Anemia

    Diunggah oleh

    MyNurse Myrna
    Table 3 summarizes drugs that can interact with oral iron supplementation by either reducing iron absorption, such as antacids, or increasing iron absorption, such as vitamin C. Table 4 lists causes of resistant iron deficiency anemia, including continuing blood loss from menstruation or bleeding, ineffective iron intake due to poor compliance or gastrointestinal side effects, and ineffective iron absorption due to malabsorption states like celiac disease or Crohn's disease.

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    Attribution Non-Commercial (BY-NC)
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    dari 1

    TABLE 3 TABLE 4 

    Drugs that Interact with Oral Iron Causes of Resistant Iron


    Supplementation Deficiency Anemia

    Drugs that reduce iron absorption Continuing blood loss 


    • Antacids • Menstruation
    • Histamine H -receptor blockers
    2 • Bleeding hemorrhoids
    • Proton pump inhibitors • Occult malignancy (especially
    • Tetracyclines gastrointestinal)
    • NSAID use and gastrointestinal bleeding
    Drugs that increase iron absorption • Intestinal parasites
    • Vitamin C
    Ineffective iron intake
    Drugs that are less well absorbed when • Poor compliance
    iron is taken • Gastrointestinal side effects
    • Levodopa (Larodopa) • Acid reduction therapy
    • Methyldopa (Aldomet)
    • Penicillamine (Cuprimine) Ineffective iron absorption
    • Quinolones • Malabsorption states
    • Tetracyclines --Celiac disease
    --Crohn's disease
    --Pernicious anemia
    • Gastric surgery

    Adapted with permission from Blood NSAID=nonsteroidal anti-inflammatory drug.


    modifiers. In: Drug Facts and Comparisons.
    St. Louis: Facts and Comparisons, 1998:238-
    Information from Glass J. Iron deficiency
    57.
    anemia. In: Rakel RE, ed. Conn's Current
    therapy. 49th ed. Philadelphia: Saunders,
    1997:349-52.

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