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Diet Lifestyle Age older than 40

Diabetic Diminished Increased blood


nephropathy kidney glucose level
function
Thickening in the
Fluid
retention Beta cells
Increased blood stimulated to
Ede
vessels pressure produce insulin
ma
caused by the
urine
Increased Impaired insulin Altered pancreatic
Blood protein leak tissue production insulin secretions
into the urine resistance to
insulin
Glucose Ineffective
Stressed kidney insulin
accumulation in
filtration the blood stream/
mechanism hyperglycemia Glucose cannot
enter the cells
Prolonged Glucosuria without insulin
elevation of Cells become
Increased glucose in starved of glucose
peripheral Polyuria
resistance Increased blood
viscosity Polyphagia
Polydipsia
UTI
Increased BP Sluggish circulation Increased
breakdown of
Weight loss protein as source of
Fatigue Decreased blood energy Increased
flow susceptibilit
y to
Decreased protein
Microvascular Decreased infection
disease circulation in lower

Retinopathy Poor wound


Leg
Weak
Numbness/ Intermittent healing amputat immune
tingling claudication ion system
Blurred
vision

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