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NURSING

GENERIC NAME ACTION CONTRAINDICATION ADVERSE REACTION


RESPONSIBILITIES
Ranitidine blocks the action Standard considerations. Minor side effects • Assess patient for
Ranitidine of histamine on stomach include constipation, epigastric or abdominal
cells, and reduces stomach diarrhea, fatigue, pain and frank or occult
acid production. Ranitidine headache, insomnia, blood in the stool,
is useful in promoting muscle pain, nausea, emesis, or gastric
healing of stomach and and vomiting. Major aspirate.
duodenal ulcers, and in side effects are rare; • Nurse should know
reducing ulcer pain. they include: agitation, that it may cause false-
Ranitidine has been anemia, confusion, positive results for urine
effective in preventing ulcer depression, easy protein; test with
recurrence when given in bruising or bleeding, sulfosalicylic acid.
low doses for prolonged hallucinations, hair loss, • Inform patient that it
periods of time. In doses irregular heartbeat, may cause drowsiness
higher than that used in rash, visual changes, or dizziness.
ulcer treatment, ranitidine and yellowing of the • Inform patient that
has been helpful in treating skin or eyes. increased fluid and fiber
heartburn and in healing intake may minimize
ulcer and inflammation of constipation.
the esophagus resulting • Advise patient to report
from acid reflux (reflux onset of black, tarry
esophagitis). stools; fever, sore throat;
diarrhea; dizziness;
rash; confusion; or
hallucinations to health
car professional
promptly.
• Inform patient that
medication may
temporarily cause stools
and tongue to appear
gray black.

BRAND NAME INDICATION DOSAGE


Treatment and 14mg TID
Zantac maintenance therapy of
duodenal ulcer;
management of
gastroesophageal reflux
CLASSIFICATION disease (GERD; including
erosive or ulcerative
disease); short-term
Anti-ulcer Agent treatment of benign gastric
ulcer; treatment of
pathologic hypersecretory
conditions (Zollinger-
Ellison); maintenance
therapy for gastric ulcer
patients at reduced dosage
after healing of acute
ulcers; treatment of
endoscopically diagnosed
erosive esophagitis;
maintenance of healing of
erosive esophagitis

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