Drug Study

NAME OF DRUG ACTION/INDICATION ADVERSE NURSING

EFFECT/CONTRAINDICATION INTERVENTION
Generic Name: Action: Interference Adverse effect: Hypersensitivity,  Skin test
CEFUROXIME with bacterial cell-wall GI disturbances, superinfection. before
synthesis and division Transient pain at IM injection administer.
Brand Name: by binding to cell-wall, site.  Advise patient
Zinacef causing cell to die. to immediately
Active against gram Contraindications: CEFTIN report rash or
Dosage: 750 mg negative and gram products are contraindicated in bleeding.
positive bacteria with patients with known allergy to  Instruct the
Classification: 2nd expanded activity the cephalosporin group of patient to take
Generation against gram negative antibiotics. drug with food
Cephalosporin bacteria. Exhibits every 12
minimal hours as
immunosuppressant prescribed.
activity.  Monitor
kidney and
Indication: Adication of liver function
gram-negative bacilli test results
and gram-positive and intake
organisms; treatment of output.
serious lower
respiratory tract, urinary
tract, skin, and
gonococcal infections,
septicaemia, and
meningitis.
NAME OF DRUG ACTION/INDICATION ADVERSE NURSING
EFFECT/CONTRAINDICATION INTERVENTION
Generic Name: Action: Omeprazole Adverse effect: Diarrhea, skin  Instruct the
OMEPRAZOLE suppresses gastric acid rashes, headache. patient to
secretion by specific take the drug
Brand Name: inhibition of the Contraindications: Diazepam, before a
hydrogen–potassium
Gastriloc phenytoin, warfarin. meal once a
adenosinetriphosphatas
e (H +, K +-ATPase) day.
Dosage: 40 mg enzyme system found at  Monitor VS
the secretory surface of  Advise
Classification: parietal cell. It inhibits patient to
Antacids and the final transport of report if with
antiulcerants. hydrogen ions (via skin rashes,
exchange with
headache,
potassium ions) into the
gastric lumen. Since the diarrhea.
H +, K +-ATPase enzyme
system is regarded as
the acid (proton) pump
of the gastric mucosa,
omeprazole is known as
a gastric acid pump
inhibitor. The inhibitory
effect is dose-
related. Omeprazole
inhibits both basal and
stimulated acid secretion
irrespective of the
stimulus.

Omeprazole does not

have anticholinergic or
histamine H 2-receptor
antagonist properties.
Indication: Duodenal and
gastric ulcers, Zollinger-
Ellison syndrome, reflux
esophagitis.