ethosuximide 250-mg Antiepileptic Control of Contraindicated CNS: Drowsiness, Give drug with
capsules or Succinamide absence (petit with ataxia, dizziness, food to prevent
Brand 250 mg per mal) seizures; hypersensitivity irritability, GI upset
Name: 5 ml of may be given in to succinamides, nervousness,
Zarontin syrup per combination lactation. headache, blurred Monitor CBC and
day with other vision, myopia, differential
antiepileptics Use cautiously photophobia, before and
especially when with hepatic, hiccups, euphoria, frequently during
other forms of renal dreamlike state, therapy.
epilepsy coexist abnormalities, lethargy,
with absence pregnancy, blood hyperactivity, Ask the client to
seizures. dyscrasias, fatigue, insomnia, report rash, joint
intermittent increased frequency pain,
porphyria. of grand mal unexplained
seizures may occur fever, sore
when used alone in throat, unusual
some patients with bleeding
mixed types of
epilepsy, confusion,
instability, mental
slowness,
depression,
hypochondriacal
behaviour, sleep
disturbances, night
terrors,
aggressiveness,
inability to
concentrate
Dermatologic:
Stevens-Johnson
syndrome,
pruritus, urticarial,
pruritic
erythematous
rashes, skin
eruptions, erythema
multiforme,
systemic lupus
erythematosus,
alopecia, hirsutism
GI: nausea,
vomiting, vague
gastric upset,
epigastric and
abdominal pain,
cramps, anorexia,
diarrhea,
constipation, weight
loss, swelling of
tongue, gum
hypertrophy
Hematologic:
Eosinophilia,
granulocytopenia,
leukopenia,
agranulocytosis,
aplastic anemia,
monocytosis,
pancytopenia
Other: Vaginal
bleeding, periorbital
edema, hyperemia,
muscle weakness,
abnormal LFTs,
renal function tests