Multiplication of bacteria
hilar & paratracheal lymphadenopathy
fever
Inflammation-activation of alveolar macrophages & neutrophils malaise
anorexia & weight loss
cough
occasional hemoptysis
Acute Primary PTB
Granuloma formation
cavities filled w/ a cheese-like mass of tubercle bacilli, dead WBC,& necrotic lung tissue
drains in tracheobronchial tree, reinfecting other normal lung tissue or spread to pleura (pleural effusion)
cough out sputum &/or blood(hemoptysis)