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Top 150 Prescriptions for 2004 - Retail

Brand Name Generic Name Indication Usual Dose Dose Side Effects
Lorcet; Lortab; Norco; Pain, moderate/ 1-2 tab Q4-6 prn; N/V/C, rash, prurits, urinary
1 hydrocodone/ apap moderately-severe MDD 8 tablets QD
Tablet
retention
Vicodin
abdominal pain, constipation,
2 Lipitor atorvastatin Dyslipidemia 10-80 mg QD Tablet
flatulence, hepatotoxicity
initial 10mg QD,
cough, dizziness, HA, N/V,
Hypertension, CHF, acute maint' 20-40mg QD,
3 Zestril; Prinivil lisinopril MI 5-20mg QD, 5-10mg
Tablet hypotension, angioedema, renal
dysfunction
QD
angina 50-100 mg QD,
Acute MI, angina dizziness, depression, insomnia,
4 Tenormin atenolol pectoris, hypertension
arrythmia 50-100 mg Tablet, IV solution
tiredness, hypotension, lupus
QD, MDD 200mg
1.7 mcg/kg/day
Synthroid; Levothroid; no common decreased bone
5 levothyroxine Hypothyroidism maintenance 100-200 Tablet, powder for IV
density, MI, seizures
Levoxyl mcg QD
Bacterial infection, 500 mg q12h or 250
Capsule, tablet, oral
6 Amoxil; Trimox amoxicillin endocarditis prophylactic, mg q8h, 2g 1 hr prior,
suspension
N/V/D, rash, hypersensitivity
gonorrhea, etc. 3g single dose
25-100 mg QD or BID, hypotension, dizziness,
12.5-25mg initial QD, N/V/D/C, HA, anorexia,
7 Esidrix; Hydrodiuril hydrochlorothiazide Edema, hypertension
increase to 50-100mg
Tablet
impotence, xanthopsia,
QD arrhythmias, lupus
500 mg QD 3 days,
Bacterial infection
8 Zithromax azithromycin (sinusitis, tonsilitis, etc.)
500 mg day 1 250mg Capsule, tablet, poder abdominal pain, N/V/D
days 2-5
anorexia, N/V/D/C, dizziness,
Hypertension, edema, 40mg BID, 20-80mg Tablet, oral solution,
9 Lasix furosemide CHF QD, 250-4000mg QD IV solution
HA, hypotension, aplastic
anemia
5-10mg QD, initial
dizziness, fatigue, flushing, HA,
10 Norvasc amlodipine Angina, hypertension 5mg QD increase to Tablet
MI, angina, arrhythmia
10mg prn
100-400mg QD, 12.5- dizziness, HA, tiredness,
Angina, CHF,
11 Lopressor; Toprol XL metoprolol hypertension
200mg QD, 50-100mg Tablet, IV solution depression, diarrhea,
QD bronchospasm
0.25-0.5mg TID, 0.5-
Anxiety, panic disorders, C, decreased libido, depression,
12 Xanax alprazolam alcohol withdrawal
1mg BID(3-6mg), 0.5- Tablet
dizziness, increased appetite
1mg BID 7-10days

1-2 puffs Q4-6h prn, 2 hypokalemia, N/V, nervousness,


13 Proventil; Ventolin albuterol Asthma, bronchospasm puffs 15-30 min prior Inhaled solution, tablet tachycardia, tremor, Stevens-
to exercise Johnson syndrome

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

50mg QD, 50mg QD, anorexia, dry mouth, dizziness,


Depression, OCD, panic
14 Zoloft sertraline disorder
25mg increase to 50mg Tablet, oral solution HA, tremor, sweating, fatigue,
QD, MDD 200mg seizures, abnormal bleeding
Hypercholesterolemia,
C, GI upset, HA,
15 Zocor simvastatin hyperlipidemia, 5-80mg QPM Tablet
hepatotoxicity, myalgia
Stroke/TIA
500mg BID initially, asthenia, flatulence, N/V/D, Vit
16 Glucophage metformin Diabetes
MDD 2550mg QD
Tablet, oral solution
B 12 deficiency, lactic acidosis
200-400mg Q4-6h,
abdominal pain, N/V/D/C, HA,
Fever, mild to moderate 400mg Q4h, 1200- Tablet, capsule, oral
17 Motrin ibuprofen pain, rheumatoid arthritis 3200mg/day, MDD drops, suspension
tinnitus, edema, GI bleeding,
hepatitis
3200mg
HCTZ 25mg, triam chest pain, hypotension,
18 Dyazide; Maxzide triamterene/ HCTZ Hypertension 37.5mg QD, MDD Capsule, talet tachycardia, anxiety, drowsiness,
50/75mg QD arrhythmias
D, dizziness, drowsiness, dry
19 Ambien zolpidem tartrate Insomnia 10mg QHS Tablet
mouth, drugged feeling
250mg Q6h, 500mg
Cystitis, skin infections, Capsule, tablet, oral abdominal pain, D, transient
20 Keflex cephalexin strepto. infections
Q12h, range 250-
suspension liver enzyme elevation
1000mg Q6h
GERD, H pylori 20-40mg QD for 4-8 abdominal pain, N/D/C, dry
21 Nexium esomeprazole eradication weeks, 20mg QD
Enteric coated capsule
mouth, HA
15mg QD, 15-30mg abdominal pain, D/C, HA,
22 Prevacid lansoprazole Duodenal ulcer, GERD
QD
Capsule
fatigue
sleep disorders, ejaculation
Depression, GAD, 10mg QD, 10-20mg
23 Lexapro escitalopram anxiety with depression QD
Tablet disorder, diaphoresis, fatigue,
N/D
5-60mg QD, 5-10mg
euphoria/depression, GI distress,
Inflammatory conditions, QD, 200mg QD 1x
24 Deltasone; Orasone prednisone adrenal hyperplasia, MS week then 80mg QOD
Tablet impaired healing, osteoporosis,
hyperglycemia, cataracts
1x month
Allergic rhinitis, chronic dry mouth, fatigue, HA,
25 Zyrtec cetirizine urticaria
5-10mg QD Syrup, tablet
somnolence
Churg-Struass syndrome,
26 Singulair montelukast Allergic rhinitis, asthma 10mg QHS Tablet
cholestatic hepatitis
Acute pain, primarry 400mg qd plus 200mg abdominal pain, diarrhea, back
27 Celebrex celecoxib dysmennorhea, prn day 1, 200mg qd, Capsule pain, dizziness, headache,
osteoarthritis, RA 100-200mg qd anemia, arrhythmias
Depression, bulemia, 20mg Qam, 20-60mg abnormal ejaculation, anorexia,
28 Prozac fluoxetine obsessive-compulsive, QD, 20mg QD, 20- Capsule, syrup dry mouth, anxiety, tremor,
body dysmorphic 80mg QD mania, suicide, seizure
abdominal pain, D/C, HA,
Glucocorticoid induced 5 mg QD, 35-70mg
29 Fosamax alendronate osteoporosis, osteoporosis Qweekly
tablet, solution musculoskeletal pain,
esophagitis, ulcer

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

Postmenopausal 0.625mg QD abdominal cramps, bloating,


30 Premarin conjugated estrogens osteoporosis, continuous or cyclic, Tablet depression, HA, migraine,
vulvar/vaginal atrophy 0.3-1.25mg QD breast cancer, hypercalcemia
Alcohol withdrawl, 2mg Q6h then 1mg depression, dizziness,
31 Ativan lorazepam anxiety disorders, Q6h, 2-6mg/day, 2- Tablet, IV solution drowsiness, HA, nausea,
insomnia, preanesthetic 4mg Qhs, 0.05mg/kg weakness, unsteadiness
Chronic idiopathic dizziness, drowsiness, fatigue,
60mg BID, 60mg BID
32 Allegra fexofenadine urticaria, seasonal allergic
or 180mg QD
capsule, tablet dysmenorrhea, dyspepsia, HA,
rhinitis otitis media, URI
minor bleeding, abdominal pain,
Platelet aggregation
33 Plavix clopidogrel inhibitor
75mg QD tablet edema, HA, chest pain, GI
ulcer, atrial fib, CHF
75mg QD to max
anorgasmia, anorexia, D, dry
Depression, generalized 225mg QD, 37.5-75mg
34 Effexor venlafaxine anxiety disorder, PMDD QD, 25mg QD max
Tablet mouth, sweating, rash, bleeding,
hypertension
200mg QD
N/V/D, flatulence, abdominal
K-Dur; K-Tab; Klor-Con; 40-100mEq divided
35 potassium chloride Hypokalemia
into 2-3 doses
Tablet pain, cardiac arrest,
Micro-K; Slow-K hyperkalemia
40mg QD, 40-80mg
36 Protonix pantoprazole GERD, peptic ulcer
QD, MDD 240mg QD
Enteric coated tablet D, HA, hyperglycemia

APAP 650mg/Propoxy abdominal pain, N/V/C,


propoxyphene napsylate/
37 Darvocet-N Pain 100mg Q4h prn, MDD tablet dizziness, liver dysfunction,
apap propoxy 600mg renal papillary necrosis
Cushing's syndrome, HA,
38 Advair fluticasone/ salmeterol Asthma, COPD 100/50, 250/50, 500/50 Inhaled solution, diskus hoarseness, asthma related
death
hemorrhage, purple toe,
2-5mg QD dose adjust hepatitis, skin necrosis,
39 Coumadin warfarin Anticoagulation
according to INR
Tablet, IV solution
hypersensitivity, cholesterol
embolization
dizziness, lightheadedness,
APAP 300-1000mg,
40 Tylenol/ Codeine acetaminophen/ codeine Pain
codeine 15-60mg Q4
Tablet, Capsule sedation, N/V, SOB,
respiratory depression
0.25mg BID X 3 days
aggravation of seizures, ataxia,
Panic disorder, seizure then 0.5mg BID,
41 Klonopin clonazepam disorders 0.5mg TID MDD 20
Tablet drowsiness, dizziness, increased
salivation, respiratory depression
mg/day
Epilepsy, migraine, 300mg TID to 1800mg ataxia, dizziness, somnolence,
42 Neurontin gabapentin peripheral neuropathy, QD, 800mg TID, 900- Capsule, tablet diplopia, myalgia, tremor,
social phobia 3600mg/day seizures, S-J syndrome
epistaxis, oropharyngeal
Asthma, dermatoses, 500-1000mcg BID, 2 Inhaled powder
43 Flonase; Flovent fluticasone rhinitis sprays/nostril QD solution
candidiasis, adrenal
suppression, anaphylaxis

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

75mg QD, blurred vision, drowsiness,


Depression,
44 Elavil amitriptyline polyneuropathy
maintenance 50- Tablet, IV solution dizziness, weakness, fatigue,
100mg HS weight gain, seizure, jaundice
150mg QHS, 150mg N/V/D/C, bradycardia, HA,
45 Zantac ranitidine Duodenal ulcer, GERD
BID
Tablet, syrup, IV
anemia, pancreatitis
N/V/D/C, anorexia, dry mouth,
150mg QD in divided blurred vision, dizziness,
46 Desyrel trazodone Depression doses, MDD Tablet insomnia, lethargy,
400mg/day arrhythmias, priapism,
seizures
Fever, pain, primary 200mg q8-12h, 500mg
N/D/C, dizziness, edema,
dysmenorrhea, Q12h, 250-500mg
47 Anaprox; Naprosyn naproxen osteoarthritis, rheumatoid Q12h, MDD 1500mg
Tablet, oral suspension tinnitus, HA, vertigo, jaundice,
CHF, GI perforation
arthritis QD for up to 6 months
Susceptible infections,
amoxicillin/ clavulanate 500mg Q12, 250 mg rash, urticaria, N/V/D, hepatic
48 Augmentin community acquired
TID
Tablet, powder
toxicity
potassium pneumonia
asthenia, cough, dizziness,
CHF, hypertension, left 2.5mg QD-BID,
hypotension, hyperkalemia, N/V,
49 Vasotec enalapril ventricular dysfunction, maintenance 2.5-20mg Tablet, IV solution
rash, angioedema, hepatic
nephropathy BID, MDD 20mg
failure
Depression, GAD, panic anorexia, C, dry mouth, anxiety,
20mg QD, MDD 75mg
50 Paxil paroxetine disorder, social anxiety
QD
Tablet, suspension abnormal bleeding, mania,
disorder, PTSD seizures
flu-like symptoms, GI
Hyperlipidemia, coronary 40mg QD, 40-80mg
51 Pravachol pravastatin events QD
Tablet disturbances, HA,
hepatotoxicity
25-100mg 1 hour prior flushing, dizziness, HA, D,
52 Viagra sildenafil Erectile dysfunction to sexual activity, Tablet dyspepsia, nasal congestion, MI,
MDD 1 time daily priapism
5mg TID, may
Muscle spasm, asthenia, blurred vision,
increase to 10mg TID,
53 Flexeril cyclobenzaprine temporomandibular
10mg TID, MDD
Tablet drowsiness, HA, confusion,
disorders hepatitis, arrhythmia
60mg/day
cough, dizziness, fatigue,
2.5mg initially, up to
54 Altace ramipril CHF, hypertension
10mg QD
Gelatin capsule hyperkalemia, N/V,
angioedema, hepatic failure
80-160mg BID, MDD cough, dizziness, fatigue, HA,
55 Diovan valsartan CHF, hypertension
320mg QD
Tablet
hypotension, angioedema
2.5/10mg QD, 5/10mg cough, dizziness, edema, HA,
56 Lotrel amlodipine/ benazepril Hypertension
QD, 5/20mg QD
Capsule
angioedema

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

headache, N/D, blurred vision,


Chronic bronchitis,
500mg QD, 250mg torsades de points,
57 Levaquin levofloxacin community-acquired
QD, 750mg QD
Tablet, IV solution
hyperglycemia, tendon
pneumonia, sinusitis
rupture
N/V/C, dizziness, dysphoria,
1 tablet Q6, daily dose
Tablet, capsule, lightheadedness, sedation, skin
58 Endocet; Percocet; Roxicet oxycodone/ apap Pain not to exceed
solution rash, pruritis, respiratory
60/4000mg
depression
ataxia, drowsiness, fatigue,
Anxiety, skeletal muscle Tablet, gel, emulsion,
59 Valium diazepam spasms, seizures
2-10mg BID-QID
suppository, IV
hypotension, respiratory
depression, sedation
anxiety, confusion, fatigue, HA,
50mg tablets Q4-6 prn, somnolence, tremors,
60 Ultram tramadol Pain, acute short term
MDD 8 tabs/day
Tablet
diaphoresis, rash, puritus,
albuminuria, seizures
IR 80mg TID may
increase to 360mg/day, C, dizziness, edema, HA,
Calan; Covera; Isoptin; Angina, arrhythmias, Capsule, tablet, IV
61 verapamil hypertension, migraine
240-320mg/day, ER
solution
hypotension, nausea, MI,
Verelan 180mg HS, 80mg TID- angina, syncope
QID
80/12.5mg QD
cough, D, fatigue, hypotension,
62 Diovan HCT valsartan/ HCTZ Hypertension initially, MDD Tablet
HA, angioedema, hepatitis
160/25mg QD
initial 10/12.5mg QD, cough, dizziness, HA, N/V,
Hypertension, CHF, acute
63 Prinzide; Zestoretic lisinopril/ HCTZ MI
maintenance 20- Tablet hypotension, angioedema, renal
40/25mg QD dysfunction
abdominal cramps, bloating,
N/V, amenorrhea, breast
1 tablet QD for 21
ethinyl estradiol/ tenderness, depression,
64 Ortho Evra Contraception days followed by7 Talet
migraine, weight changes,
norelgestromin days 1 inactive tablet
hypertension, arterial
thromboembolism
20mg QD, 10-40mg impotence, fatigue, somnolence,
Depression, headache,
65 Celexa citalopram panic disorder
QD, 20-30 mg QD, tablet, solution nausea, rhinitis, sweating, dry
MDD 60 mg/day mouth, D, leukopenia, MI
cough, dizziness, hyperkalemia,
5mg BID, 20-40mg
66 Accupril quinapril CHF, hypertension
BID, 20-80mg BID
Tablet hypotension, N/V, angioedema,
hepatic failure
drowsiness, dizziness, tremor,
hypotonia, irritability, HA, N/V,
67 Soma carisoprodol Musculoskletal disorders 350mg TID and HS Tablet, capsule
tachycardia, facial flushing,
anaphylactoid shock

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

15-30mg QD, MDD


45mg QD, MDD in anemia, edema, HA, myalgia,
68 Actos pioglitazone Type 2 diabetes mellitus
combo therapy 30mg
Tablet
weight gain, hepatotoxicity
QD
Allergy, anesthesia CNS depression, dermatitis,
25mg HS, or 12.5mg
adjunct, motion sickness, drowsiness, EPS, N/V, dry
before meals and HS, Tablet, syrup,
69 Phenergan promethazine nausea and vomiting,
25-50mg IM or IV, suspension, IV solution
mouth, lower seizure threshold,
postoperative pain, agranulocytosis, respiratory
N/V 25-50mg rectally
sedation depression
5mg QD, 35mg arthralgia, diarrhea, HA, rash,
Osteoporosis prevention,
70 Actonel risedronate treatment, Paget's disease
Qweek, 30mg QD for Tablet abdominal or stomach pain,
2 months colitis
20mg IR then 20mg
Angina pectoris, after 7 hrs, 30-60mg HA, dizziness, N/V/D/C,
71 Imdur isosorbide mononitrate gastrointestinal bleeding, QD, 10-20mg BID w/ Tablet tachycardia, arrhythmias,
myocardial infarction beta blocker, 20mg cardiac failure
QD-TID
200-300mg QD or N/V, prurits, rash, renal failure,
Calcium oxalate calculi, BID, MDD agranulocytosis, anemia, bone
72 Zyloprim allopurinol gout, uric acid calculi 300mg/dose and
Tablet, powder
marrow supression,
800mg/day hepatotoxicity
CHF, diabetic
12.5mg QD titrate at 7
nephropathy, asthenia, fatigue, D, dizziness,
73 Cozaar losartan hypertension, stroke
day intervals to 50mg Tablet
hypotension, angioedema
QD, 25-100mg QD
prevention
200mcg QD, 0.2-
confusion, dry mouth,
0.6mg in divided doses
Hot flashes, hypertension, Tablet, IV solution, hypotension, N/V/C, weakness,
74 Catapress clonidine opiate withdrawal
(BID), 0.1mg BID-
patch somnolence, dizziness, sedation,
QID for 2 days, then
chest pain, tachycardia
taper,
500-750mg Q12,
Susceptible infections, 500mg Q12 for 10
N/D, HA, restlessness, dizziness,
sinusitis, UTI, gonorrhea, days, 250mg Q12, Powder for suspension,
75 Cipro ciprofloxacin infectious diarrhea, 250mg QD, 500mg IV solution
rash, convulsions, increased
intracranial pressure
anthrax Q12 for 5-7 days,
500mg Q12 60days
agitation, anxiety, confusion, C,
Depression, smoking 150mg initially for 3
76 Wellbutrin bupropion cessation days then 150mg BID
Tablet dry mouth, tremor, psychosis,
arrhythmias
2.5-5mg QD initially,
allergic skin reactions,
1.25-20mg QD or
77 Diabeta; Micronase glyburide Type 2 diabetes mellitus
divided, MDD 20mg
Tablet heartburn, hypoglycemia, N,
severe hypoglycemic episodes
QD
4mg QD or in 2 anemia, edema, HA, URI,
78 Avandia rosiglitazone Type 2 diabetes mellitus
divided doses
Tablet
weight gain, hepatotoxicity

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

2g 1h prior to
Endocarditis prophylaxis,
procedure, 250-500mg N/V/D, rash, hemolytic anemia,
79 Pen-Vee K; Veetids penicillin VK pneumo infections,
Q6, 125-250mg Q6-8
Tablet
hypersensitivity reactions
strepto. infections
for 10 days
abdominal pain, arthralgias,
Hypercholesterolemia,
80 Zetia ezetimibe sitosterolemia
10mg QD Tablet back pain, cough, D, HA,
fatigue, sinusitis
cataracts, Cushing's syndrome,
4-48mg QD, MS
Adrenal insufficiency, euphoria, depression, ulcer,
160mg QD for 1 week
81 Medrol; Solu-Medrol methylprednisolone inflammatory conditions,
then 64mg QOD for 1
Tablet growth depression, HTN,
multiple sclerosis hypokalemia, osteoporosis,
month
glaucoma
anorexia, N, bitter/bad taste,
folic acid deficiency,
1mg QD, 0.5-5mg QD, irritability, confusion, altered
82 Folvite folic acid hyperhomocysteinemia,
0.8-1mg QD
Tablet, IV solution
sleep pattern, allergic
neural tube defects
sensitization
20mg QD for 4-8
Duodenal ulcer, GERD,
weeks, hypersecretory- abdominal pain, N/D, HA,
83 Aciphex rabeprazole H. pylori eradication,
60-120mg QD up to
Tablet
insomnia
hypersecretion
100mg in 1 dose

Initial 5mg QD, MDD allergic skin reactions, dizziness,


84 Glucotrol glipizide Type 2 diabetes mellitus 40mg QD, MDD of Tablet HA, hypoglycemia, N/D, severe
XR 20mg QD hypoglycemic episode
chest pain, asthenia, HA,
Benign prostatic 0.4mg QD, may
85 Flomax tamsulosin hyperplasia increase to 0.8mg QD
Capsule insomnia, cough, rhinitis, N/D,
arthralgia, priapism
AV block, bradycardia,
30mg QID, MDD dizziness, fainting, gingival
Cardizem; Cartia XT; Capsule, tablet, IV
86 diltiazem Angina, hypertension 360mg QD, 60-120mg hyperplasia, HA, peripheral
Tiazac BID
solution
edema, cardiac conduction
disturbances
abdominal pain, arthralgia,
agitation, anxiety, HA, N/V,
Bipolar mania, 2-3mg QD, 1mg BID Tablet, oral solution,
87 Risperdal risperidone schizophrenia increase to 4-8mg QD powder
rhinitis, tachycardia,
hyper/hypothermia, mania,
polydipsia
Duodenal ulcer, GERD, 20mg QD, doses N/V/D/C, dizziness, URI, rash,
88 Prilosec omeprazole H. pylori eradication, greater than 80mg QD Capsule, tablet abdominal pain, hepatotoxicity,
hypersecretion should be divided pancreatitis
abdominal cramps, bloating,
1 yellow tablet QD for N/V, amenorrhea, breast
drospirenone/ ethinyl
89 Yasmin Contraception 21 days and 1 white Tablet tenderness, depression,
estradiol tab for 7 days migraine, weight increase or
decrease, hypertension

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

100mg BID day 1 then


100mg QD, 100mg gastrointestinal distress,
Susceptible infections,
BID for 60 days, photosensitivity, increased BUN,
90 Monodox; Vibramycin doxycycline anthrax, chlamydia,
100mg BID for 7 days,
Capsule, tablet
bulging fontanels, benign
cholera, lyme disease
100mg BID for 10-20 intracranial hypertension
days
N/V/D, flatulence, muscle pain,
Hypercholesterolemia, 160mg QD, 54-160mg
91 Tricor fenofibrate hypertriglyceridemia QD, MDD 160mg QD
tablet rash, rhinitis, hepatotoxicity,
rhabdomyolysis
C, dry mouth, dyspepsia,
50mg BID, target dose dizziness, somnolence, rhinitis,
Acute bipolar mania, 400mg/day, 25mg tachycardia, postural
92 Seroquel quetiapine schizophrenia BID, range 300-
tablet
hypotension, weight gain,
400mg/day leukopenia, seizures, tardive
dyskinesia
abdominal pain, amoroexia, dry
5-60mg/day in divided mouth, weight loss, dysphoria,
Adderall; Dexedrine; amphetaimine salts;
93 Narcolepsy, ADHD doses, 10mg QD MDD Tablet euphoria, HA, tremor, insomnia,
DextroStat dextroamphetamine 40mg QD chest pain, hyperthermia,
irregular heartbeat

10-15mg IR or 20mg restlessness, behavior


SR QD, 7.5mg BID disturbances, slurred speech,
ADHD, fatigue,
94 Concerta; Ritalin methylphenidate narcolepsy
titrate up to MDD 60 Tablet, capsule loss of appetite, hallucinations,
mg/day, 10-60mg/day hypertension, tachycardia,
BID or TID thrombocytopenia
burning, epistaxis, HA, viral
2 sprays each nostril
95 Nasonex mometasone Rhinitis
QD
Cream, lotion, ointment infection, adrenal suppression,
glaucoma
Allergic rhinitis, dizziness, dry mouth, flu like
96 Clarinex desloratadine seasonal/perennial
5mg QD Tablet, syrup
symptom
Atherosclerosis, CHD-
initial 20mg QD,
prevention, diarrhea, constipation, headache,
97 Mevacor lovastatin Hypercholesterolemia,
maintenance 10-80mg Tablet
nausea, abdominal pain
QD
Mixed dyslipidemia
1 tablet QD edema, dizziness, abdominal
98 Hyzaar losartan/ HCTZ Hypertension (50/12.5mg), MDD Tablet pain, N/D, cough, URI, back
100/50mg pain
drowsiness, lethargy,
Edema, hirsutism, gynecomastia, HA,
100mg QD initial
99 Aldactone spironolactone hypertension,
MDD 400mg/day
Tablet hyperkalemia, N/V/D, urticaria,
hypokalemia agranulocytosis, gastric
bleeding, metabolic acidosis
asthenia, dizziness,
1-2mg QD initially, 1-
100 Amaryl glimepiride Type 2 diabetes mellitus
4mg QD, MDD 8mg
Tablet hypoglycemia, N, severe
hypoglycemic episode

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

0.125-0.5mg QD,
Capsule, tablet, IV anorexia, N/V/D, HA, visual
101 Digitek; Lanoxin digoxin CHF titrate doses every 2
solution disturbances, arrhythmias
weeks
blurred vision, confusion,
7.5-30mg HS,
fatigue, hangover, lethargy,
102 Restoril temazepam Insomnia gradually taper to Capsule, gel capsule
dependence, N/D, drowsiness,
discontinue
HA, hypotension
400mg QD, 150mg
Bone marrow transplant
single dose, 400mg on Tablet, oral suspension, elevated liver enzymes, HA,
103 Diflucan fluconazole prphylaxis, candidiasis,
first day and 200mg IV solution N/V, rash, itching, anaphylaxis
cryptococcal meningitis
QD for 10 -12 days
Osteoporosis prevention, hot flashes, leg cramps, retinal
104 Evista raloxifene treatment
60mg QD Tablet
vein occlusion
blurred vision, eyelash changes,
1 drop in affected eyes
105 Xalatan latanoprost Glaucoma
QPM
Othphalmic solution eyelid skin darkening, iris
pigmentation, macular edema
allergic skin reactions, injection
individualized,
site pain, lipodystrophy, rash,
106 Lantus insulin glargine Diabetes administered QD same IV solution
diabetic ketoacidosis, severe
time every day
hypoglycemia
angina, atrioventricular block,
bradycardia, fatigue, dizziness,
Angina, CHF,
3.125mg BID initially HA, N/V/D, erectile
107 Coreg carvedilol hypertension, post
up to 50 mg BID
Tablet
dysfunction, rhinitis,
myocardial infarction
hepatotoxicity,
thrombocytopenia
MDI- 2 inhalations
N/V/D, hypertension,
QID, MDD 12/ 24hrs,
tachycardia, HA, dry mouth,
108 Combivent; DuoNeb albuterol/ipratropium COPD inhalation solution- 1- Inhaled solution
dyspepsia, coughing, sinusitis,
3ml vial QID, MDD 6
URI, arrhythmias
doses/24hr
asthenia, GI problems, headache,
109 Crestor rosuvastatin hypercholesterolemia 5-40mg QD tablet myalgia, pharyngitis, upper
respiratory infections
N/V, anorexia, rash, urticaria,
chronic bronchitis,
trimethoprim/ 1 DS tablet or 2 SS Tablet, suspension, IV severe allergic reactions,
110 Bactrim; CoTrim; Septra shigellosis, traveler's
tablets Q12 for 14 days solution fulminant hepatic necrosis,
sulfamethoxazole diarrhea, UTI
aplastic anemia
1g BID for 7-10 days,
N/V, HA, thrombotic
Genital herpes, herpes 1g QD for 5 days, 2g
111 Valtrex valacyclovir labialis, herpes zoster BID for 1 day, 1g TID
Capsule thrombocytopenic purpura,
hemolytic uremic syndrome
for 7 days
abnormal gait, accidental injury,
2.5-10mg IM Q4
Agitation, bipolar asthenia, C, dry mouth,
(MDD 10mg), 5-20mg
112 Zyprexa olanzapine disorder, bipolar mania,
QD, 10-15mg QD, 1-
Tablet dyspepsia, dizziness,
borderline, schizophrenia parkinsonism, tardive
5mg QD, 5-10mg QD
dyskinesia

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

edema, hypotension,
palpitations, anxiety, dizziness,
113 Cardura doxazosin BPH, hypertension 1-16mg QD tablet
fatigue, headache, somnolence,
vertigo, abdominal pain, nausea
asthenia, dizziness, sedation,
10-30 mg IR Q4 prn, N/V/C, dry mouth, pruritis,
114 OxyContin oxycodone Pain
10-40mg CR Q12
Tablet
apnea, respiratory depression,
hypotension
Cushing's syndrome, euphoria,
Dermatoses, neoplastic 8-16mg QD, neo/neph depression, osteoporosis,
Aristocort; Azmacort;
115 triamcinolone disease, nephrotic 16-40mg QD, lupus 3- Tablet, syrup hypertension, GI distress,
Kenalog; Nasocort AQ syndrome, rhinitis, lupus 30mg QD cataracts, glaucoma,
hyperglycemia
amenorrhea, breakthrough
bleeding, spotting, breast
Atropic urethritis,
enlargement, breast tenderness,
vaginitis, breast cancer, Cream, ointment, gel,
Climara; Estrace; Tablet 0.5mg QD, chloasma, melasma, pruritis,
116 estradiol postmenopausal insert, tablet,
depression, headache, edema,
Estraderm; Vivelle osteoporosis, prostate
Patch 0.025mg QD
transdermal patch
weight changes, leukorrhea,
cancer, vulvar atrophy
vaginal discomfort, nausea,
vomiting, skin irritation
abdominal pain, dyspepsia,
fexofenadine/ 1 tablet BID
117 Allegra-D Seasonal allergic rhinitis
(60/120mg)
Tablet agitation, HA, insomnia, nausea,
pseudoephedrine palpitation, URI
abdominal pain, D, flatulence,
Hyperlipidemia, reduction dyspepsia, muscle pain, rash,
118 Lopid gemfibrozil of coronary risk
600mg BID Tablet, capsule
xerostomia, abnormal liver
funtion tests, rhabdomyolysis
Ortho Tri-Cyclen; Ortho abdominal pain, N, HA, breast
1 patch Qweek for 3
ethinyl estradiol/ symptoms, emotional lability,
119 Tri-Cyclen Lo; TriNessa; Contraception weeks, week 4 is patch Tablet
venous thrombosis,
norgestimate free
Tri-Sprintec hypertension, MI
constipation, drowsiness,
Gastroesophageal reflux dystonic reactions, fatigue, fluid
0.15mg/kg, Solution IV, Syrup,
120 Reglan metoclopramide disease, Nausea and
0.25mg/kg/dose IV Tablet
retention, restlessness, sedation,
vomiting tremors

Anxiety, pruritus
121 Atarax; Vistaril hydroxyzine 50-100mg QD Capule, suspension drowsiness, dry mouth, headache
Hypertension, 150mg QD, MDD D, HA, dyspepsia,/heartburn,
122 Avapro irbesartan nephropathy 300mg
Tablet
fatigue, URI, angioedema
asthenia, fatigue, tremor, ataxia,
25-50mg QD initial, confusion, dizziness, diplopia,
200mg BID N, speech or language problems,
123 Topamax topiramate Seizures
maintenance, MDD
tablet, capsule
hyperthermia, anemia,
1600mg leukopenia, dyspnea, hepatic
failure

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

dizziness, fatigue, asthenia,


25-100mg repeat after
dyspnea, flushing, numbness,
124 Imitrex sumatriptan Headache 2 hours if needed, Nasal spray
sweating, N/V/D, myocardial
MDD 200mg/day
infarction, hypertensive crisis
anorexia, N/C, dry mouth,
weight loss, dizziness, HA,
Attention deficit 40mg QD, target 80mg
125 Strattera atomoxetine hyperactivity disorder QD, MDD 100mg QD
Capsule insomia, dysmenorrhea, erectile
disturbance, tachycardia,
paresthesia, mania
blurred vision, C, HA, dry
2mg IR BID, 4mg XR
126 Detrol tolterodine Overactive bladder
QD
Tablet mouth, dyspepsia,
anaphylactoid reactions
Sinusitis, chronic
300mg BID for 10
bronchitis, community
127 Omnicef cefdinir acquired pneumonia, skin
days, or 600 mg QD Capsule, suspension N/D, vaginal moniliasis, HA
for 10 days
infections
128 Antivert meclizine Motion sickness, vertigo 12.5-25mg BID tablet drowsiness, sedation, xerostomia
anxiety, confusion, fatigue, HA,
2 tablets Q4-6 prn, somnolence, tremors,
129 Ultracet tramadol/ apap Pain, acute short term
MDD 8 tabs/day
Tablet
diaphoresis, rash, puritus,
albuminuria, seizures
130 Cleocin clindamycin Bacterial infection 150-300 mg Q6hr Capule diarrhea, nausea, rash
ataxia, dizziness, headache,
peripheral neuropathy, seizures,
anorexia, GI discomfort,
Cream, gel, tablet, IV metallic taste perversion, N/V,
131 Flagyl metronidazole Infection 7.5mg/kg IV QD
solution symptomatic candida
cervicitis/vaginitis, vaginal
discharge, disulfiram-like
reaction, herxheimer reaction
1-2 tablet TID, AAA Suspension, ointment,
132 Mycostatin; Nystop nystatin Candidia infections
TID, cream, powder, tablet
nausea and vomiting
bradycardia, chest pain, edema,
hypotension, dizziness, fatigue,
headache, insomnia,
Initial 2.5/6.25mg QD, hyperglycemia, hyperuricemia,
133 Ziac bisoprolol/ HCTZ Hypertension titrate to 20/12.5mg Tablet hypokalemia, diarrhea,
QD dyspepsia, nausea, impotence,
cough, rhinitis, upper respiratory
tract infection, muscle cramps,
myalgia

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

5-10mg/kg/day, MDD
anorexia, alopecia, asthenia,
60mg/kg/day,
Epilepsy, mania, migraine ataxia, N/V/D, HA, diplopia,
134 Depakote divalproex prophylaxis
750mg/day, 250mg capsule
weight changes, hepatic failure,
BID, MDD
thrombocytopenia
1000mg/day
10mg QD,
maintenance 20-40mg cough, dizziness, edema,
135 Lotensin benazapril Hypertension, CHF QD, MDD 80mg QD, Tablet hyperkalemia, hypotension,
5mg QD maintenance angioedema
5-10mg QD
Initial 200mg, then dizziness, light-headedness,
136 Minocin minocycline Infection, Acne
100mg BID
capsule
vertigo
abnormal dreams/thinking,
somnolence, C, increased
15mg HS, MDD 45mg
137 Remeron mirtazapine Depression
HS
Tablet appetite, weight gain,
agranulocytopenia, mania,
seizures
Cushing's syndrome, epistaxis,
2 sprays each nostril HA, nasal dryness/stinging,
138 Pulmicort; Rhinocort Aqua budesonide Rhinitis
BID
Inhaler, spray
throat irritation, cataract,
glaucoma, adrenal suppression
bradycardia, AV block,
Angina, anxiety, 80-320mg IR QD cognitive dysfunction,
139 Inderal propranolol arrhythmias, CHF, divided doses, low Tablet, capsule, IV depression, insomnia, parethesia,
hypertension, migraine initial titrate to dose anorexia, N/V, dyspnea,
bronchospasm
N/V/C, sedation, heart rate
Cough, upper respiratory 5ml orally Q4-6 not to changes, blood pressure
140 Phenergan/ Codeine promethazine/ codeine symptoms exceed 30ml/day
Syrup
changes, respiratory
depression
1mg HS initial, 1- edema, hypotension, palpitation,
Benign prostatic 10mg HS MDD 20mg tachycardia, asthenia, dizziness,
141 Hytrin terazosin hyperplasia, hypertension QD, 1-5mg QD-BID
Capsule
nasal congestion, blurred vision,
MDD 20-40mg QD blood dyscrasias, priapism
N, HA, abdominal pain, back
1 tablet QD
conjugated estrogens/ Menopausal symptoms, pain, depression, deep vein
142 Premphase; Prempro osteoporosis
(0.625/2.5mg) or Tablet
thrombosis, stroke, myocardial
medroxyprogesterone (0.625/5mg)
infarction
anorexia, N/V/D, fatigue,
143 Aricept donepezil Alzheimers type dementia 5-10mg HS Tablet, solution
insomnia, muscle cramps
blurred vision, dizziness,
headache, nausea, nervousness,
144 BuSpar buspirone Anxiety 5-7.5mg BID Tablet
excitement, anger/hostility,
confusion, numbness, weakness

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 150 Prescriptions for 2004 - Retail

drowsiness, dizziness, HA,


nervousness, N/V,
145 Skelaxin metaxalone Musculoskletal disorders 800mg TID-QID Tablet
gastrointestinal upset, jaundice,
hemolytic anemia, leukopenia

abdominal pain, N/D, flatulence,


Osteoarthritis, rheumatoid 7.5mg QD, MDD edema, HA, dizziness, insomnia,
146 Mobic meloxicam arthritis 15mg QD
Tablet
arthralgia, anemia, angina,
CHF, dyspnea, leukopenia
asthenia, confusion, dizziness,
25mcg/hr transdermal
sedation, N/V/C, dry mouth,
gradually increase to
147 Actiq; Duragesic fentanyl Pain, chronic
300mcg/hr prn, replace
Patch pruritis, sweating, urinary
retention, arrhythmias, chest
patch every 72 hours
pain, apnea, hypoventilation
diarrhea, nausea, vomiting,
central nervous system effects;
agitation, confusion, dizziness,
Tablet, capsule,
Chicken pox infections, hallucinations, somnolence,
148 Zovirax acyclovir Herpes infections
200-800mg QID prn ointment, powder for
malaise, burning or stinging of
IV, suspension
the skin (topical), phlebitis (IV),
increased serum creatinine and
BUN (IV)
Esophagitis, GERD,
Tablet, oral suspension,
149 Pepcid famotidine hyperacidity, ulcer 10-40mg BID
IV solution
constipation, diarrhea, dizziness
disease
individualized, allergic skin reactions,
isophane insulin
150 Humulin N; Novolin N Diabetes mellitus administered QD same IV hypoglycemia, lipodystrophy,
suspension (human) time every day pain

* Listed by number of prescriptions dispensed as compiled by NDC Health and found on www.rxlist.com
Top 50 Drugs Used in Hospitals in 2004

Brand Name Generic Name Dosage Forms Indication Dose Side Effects
anemia in cancer,
150u/kg iv/sc 3xwk
HIV, renal failure, arthralgias,clotted
1 Epogen; Procrit (erythropoietic) epoetin alfa SC x8wks, then access,HA,CVA,DVT,HTN,MI,s
reduction of blood eizure
300u/kg 3xwk
transfusion
DVT, ischemic-
non-QT post-MI, 1mg/kg sq q12h x erythema, pain, anemia, fever,
2 Lovenox (anticoagulant/LMWH) enoxaparin deep SC diarrhea, nausea, confusion,
ischemic unstabe 5-17days dyspnea, edema
angina
gram(-) infection
(bone/joint;
gonorrhea; lower
Rocephin (3rd gen A=1-2g q12- diarrhea;pain@injec;rash;↑liver
3 ceftriaxone IV/IM resp; meningitis; enzyme;revserse gallbladder
cephalosporin) 24h;max 4g/day dx;hemolysis (rare)
otitis media; PID;
septicemia; UTI;
skin
nausea/vomit post- 32mg/IV q30 min
Zofran (antiemtic;CNS & 5-HT
4 ondansetron SC;tab;ODT;sol op; prior; 8mg q30 min diarrhea; constipation; dry mouth;
HA; malaise/fatigue; anaphylaxis
receptor antagonist)
chemo/radiation prior then q8h
anemia in cancer,
2.25mcg/kg qwk;
renal edema; fatigue; diarrhea; N/V;
5 Aranesp (erthyropoietic) darbepoetin alfa SC may ↑ to 4.5 HA; HTN; dehydration; dyspnea;
failure/insufficienc fever; arrthymia; sepsis; CHF;
mcg/kg
y
RA; crohn's dx; 3mg/kg over 2h at
Remicade (tumor necrosis factor ab pain; N/V; hepatotox (rare);
6 infliximab IV ankylosing wks0,2,6 then fungal infection; lymphoma;
α neutralizer) blood dyscrasias
spondylitis q8wks
prevention of
Neulasta (hematopoietic/colony 6 mg once per bone pain; N/V; flu-like sx; adult
7 pegfilgrastim SC febrile neutropenia resp distress syndrome; sickle cell
stim factor) chemo cycle crisis; splenic rupture (rare)
in chemo pts

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

B-cell, non-
Rituxan 375 mg/m2 qwk x4- lyphopenia;
N/V; HA; dizziness; rash;
8 rituximab IV hodgkins angina; sepsis; renal
(antineoplastic/monoclonal Ab) 8 doses tox; steven-johnson syndrome;
lymphoma
PCN resistant β-
lactamase
organism;
9 Zosyn (extended spectrum PCN) piperacillin/tazobactam IV (pwd) 3.375 g/iv q 6h allergicrash;
rxn; N/V; diarrhea; HA;
injection rxn
appendicitis; PID;
peritonitis;
pneumonia
myeloid leukemia
10mcg/kg/day
receiving chemo;
Neupogen hematopoietic/colony given IV over 4- resp
bone pain; N/V; flu-like sx; adult
10 filgrastim IV/SC pbone marrow distress syndrome; sickle cell
stim factor) 24h; 5mcg/kg/day crisis; splenic rupture (rare)
transplant;
SC
neutropenia
2mcg/kg bolus then
Natrecor CHF (acutely hypotension; CNS; solmnolence;
11 nesiritide IV 0.001mcg/kg/min tremor; nausea; facial itching
(adrenergic/cardiovascular) decompenstated
contin IV
induction=20-40mg
anesthesia; q10sec
12 Diprivan (anesthetic adjunct) propofol IV injection pain; invol. Muscle move; N/V; anaphylaxis
sedation maintain=50-
200mcg/kg/min
IV bolus=
Integrilin (iibiiia 180mcg/kg; MD minor bleeding; hypotension;
ACS w/ or w/o
13 inhibitor/platelet aggregation eptifibatide IV 22.6mg; maintain= major bleeding; hemorrhagic
PCI stroke
inhibitor) 2mcg/kg/min;MD
15mg/hr x72hr
measles; rubella;
varicella; ped HIV; facial flushing; infusion
Carimune NF; Gammar-P IV; B-cell lymphoma; depends on dx rxn(fever,HA; N/V); local pain;
14 immune globulin IV acute renal failure; anaphylaxis;
Polygam S/D (immune serum) bone marrow being treated anemia; thrombosis; steven-
transplant; johnson; acute resp. distress

Hepatitis A

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

initial =300mg/m2 N/V; electrolyte disturbance;


myelosuppresion; periph.
15 Paraplatin (antineoplastic) carboplatin IV; injection ovarian cancer day 1 q 4wks x6 Neuropathy; visual
cycles distrubances(rare)

2-day dose q2wks ab pain; N/V/D; anorexia;


=(1) 85 mg/m2 in stomatitis; back pain; cough;
colorectal cancer fever; fatigue; anemia;
16 Eloxatin (antineoplastic) oxaliplatin IV (pwd) 250-500ml D5W anaphylaxis; colitis; dyspnea;
(combo w/others)
over 2hr y-lined edema; febrile neutropenia;
neuropathy; thromboembolism
with other Rx)
B=depends on alopecia; asthenia; neuropathy;
breast cancer; lung
Taxotere (antineoplastic/mitotic stage; L&P=75 N/V/D; stomatitis; fever; fluid
17 docetaxel IV cancer; prostate retention; febrile neutropenia;
inhibitor) mg/m2 over 1hr hepatoxicity; infection;
cancer myleosuppression
every 3 wks
agitation; N/V;
0.5-3% bradycardia/tachycardia;
18 Ultane (anesthetic) sevoflurane inhalant anesthesia concentration w/ or hypotension; laryngospasm; resp.
depression; malignant
w/o nitrous oxide hyperthermia(rare); seizure(rare)

HC=4mg
hypercalcemia of infusion>15min; ab pain; N/V/D; alopecia;
malignancy; repeat in 7 days dermatitis; arthraglia; bone pain;
Zometa (Ca regulator;
++
myalgia; chills; fever; fatigue;
19 zoledronic acid IV (pwd) multiple myeloma prn; MM=4mg cough; dyspnea; HA; UTI; URTI;
bisphosphonate)
& metastatic bone infusion>15min 3- hypophosphatemia; hypoK;
hypoMG; anemia; renal tox
lesion 4x wk + oral Ca
w/vitD

aspergillosis;
candida infection; 70mg infusion day
candidemia; 1; then 50mg/day; facial swelling; fever; HA; ↑ liver
20 Cancidas (antifungal/systemic) caspofungin IV (pwd) enzyme; N/V; infusion rxn;
empirical tx for duration depends pruritus; rash
fugnal infection in on dx & response
febrile neutropenia

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

B=1250mg/m2 on
days 1 & 8 of each
21 day cycle;
L=same for 3wk tx; cutaneous rxn; flu-like sx; N/V;
breast cancer; lung
Gemzar 4wk peripheral edema; proteinuria;
21 gemcitabine IV (pwd) cancer; pancreatic hepatotoxicity; arrhythmia; CHF;
(antineoplastic/antimetabolite) tx=1000mg/m2 on MI; pulm toxicity; renal failure;
cancer myleosuppression; vasculitis
days 1,8,&15 of
28day cycle;
P=1000mg/m2/wk
for 7 wks
0.25mg/kg bolus
PCI; unstable over 5min; then
ReoPro (iibiiia inhibitor/platelet hypotension; minor bleeding;
22 abciximab IV angina undergoing 0.125mcg/kg/min N/V; major bleeding;
aggregation inhibitor) thrombocytopenia
PCI (max 10
mcg/min)for 10hr;
hemostatis of
Thrombin-JMI (topical 100units /ml allergic rxn; antibody
23 thrombin sol; pwd accessible formation(rare)
hemostatic) topically prn
capillaries/venules

gram(-) infection
(bone/joint;
dose depends on
endocarditis; lower
where infection;
resp;
mild/mod infection injection
N/V/D; thrombophelbitis;
24 Primaxin (antibiotic) cilastatin/imipenem IV; IM (pwd) gynecological; pain; anaphylaxis(rare);
= 250-500mg q6h seizures(high doses)
intra-ab;
IV; IM=500-750mg
polymicrobic;
q12hr
septicemia; skin;
UTI;

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

gram(+)infection
(entercoccus-
resistant
strain/S.aureas-
resistant strain 600mg IV/oral
only); S.agalactiae, q12h-duration N/V/D; optic & peripheral
25 Zyvox (anti-infective/antibiotic) linezolid tab; oral susp; IV neuropathy; myleosuppression
S.pneumoniae, depends on
S.pyogenes infection type
infections;
pneumonia; skin &
skin structure
infection

Avinza; Kadian; MSContin; moderate/severe N/V; HA; dizziness; constipation;


tab/cr tab; oral sol; depends on pt pain
MSIR; Oramorph; Roxanol acute pain; fluid retention; sedation;
26 morphine rectal supp; IV; severity; typically weakness; allergic rxn;
(analgesic/opioid/anesthetic moderate/severe confusion; hypotension; resp.
IM; SC 5-30mg q4h depression; histamine release
adjunct) chronic pain(CR)
prophylaxis for
perioperative
Trasylol (hemostatic/blood 1-2million units
27 aprotinin IV blood loss during anaphylaxis; thrombosis; shock
modifier) over 20-30mins
coronary artery
bypass graft
colorectal cancer
Camptosar alopecia; diarrhea; hepatic
(usually combo dose depends on dysfxn; grade 3/4 infection;
28 (antineoplastic/topoisomerase I irinotecan IV neutropenic fever; severe
w/leucovorin/5- regimen selected
inhibitor) myleosuppression
fluorouracil
endometriosis; E=3.75mg q month alopecia; bone pain; depression
precocious x6; PC=7.5mg q exacerbation; hot flashes;
Lupron (gonadotropin releasing memory disorder; N/V;
29 leuprolide IM only puberty; prostate month; peripheral edema; vaginal
hormone agonist)
cancer; uterine UFT=3.75mg q hemorrhage; thrombo/pulm
embolism
fibroid tumor month x3

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

supraventricular 6mg bolus over 1-2 chest pain/pressure; dyspnea;


tachycardia; sec; ↑12mg q 1-2 HA; lightheadedness; flushing;
neck/throat/jaw discomfort;
30 Adenoscan (antiarrhythmic) adenosine IV thallium-201 min; nausea; bradycardia;
myocardial 140mcg/kg/min for bronchoconstriction; arrhythmia;
2nd degree heart block
imaging 6min

2mg oral 1hr before


chemo/radiation;
chemo induced
10mcg/kg IV
Kytril (antiemetic/serotonin N/V; radiation ab pain; asthenia; constipation;
31 granisetron tab/oral sol; IV 30min before; 1mg diarrhea; HA; somnolence
receptor antagonist) N/V; postoperative
IV immediately
N/V
before/removal
anesthesia
respiratory
15mg/kg during
Synagis (humanized monoclonal syncytial virus rhinits; upper resp. infection;
32 palivizumab IM (pwd) RSV season x5 wheezing; rash; injection pain
antibody) (rsv) prevention
doses
high risk infants
anticoagulant
w/unstable angina back/pelvic/ab pain; HA; pain;
N/V; dyspepsia; insomnia;
undergoing 1mg/kg bolus then
Angiomax (anticoagulant/hirudin anxiety; hypotension; HTN;
33 bivalirudin IV (pwd) percutaneous 2.5mg/kg/hr bradycardia; fever; hemorrhage;
related agent) retroperitoneal/intracranial bleed;
transluminal infusion x4hr sepsis; v.fib; kidney failure;
coronary cerebral ischemia; thrombus
angioplasty
cough; HA; N/V; apnea;
anesthesia I=0.5-3% in laryngospasm; pharyngitis; HTN;
34 Suprane (anesthetic) desflurane inhalant (induction/maintai oxygen/nitrous brady/tachycardia; CNS
stim(during induction);
n) oxide; M=pt based oxyhemoglobin desaturation
load=4mg/kg over
Herceptin breast cancer anemia; leukopenia; diarrhea;
90min; cardiomyopathy; allergic rxn;
35 (antineoplastic/humanized trastuzumab IV (pwd) expressing HER2 infusion rxn; pulm event;
main=2mg/kg over
monoclonal antibody) protein nephrotic syndrome(rare)
30min wk

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

aerobic gram (-)


(P.aeruginosa);
some gram (+) typically start w/2g; HA; colitis; diarrhea; dyspepsia;
Maxipime (4th generation (S.aureus); febrile frequency local rxn; phlebitis;
36 cefepime IV inflammation; pain;
cephalosporin) neutropenia; intra- determined by encephalopathy; seizure
ab infection; infection
pneumonia; UTI;
skin
Xigris (anti-
37 inflammatory/coagulation drotrecogin alfa IV (pwd) severe sepsis 24mcg/kg/hr x96hr serious bleeding events
inhibitor; profibrinolytic)
AIDS related
kaposi's
sarcoma(2nd line); abnormal liver fxn; alopecia;
135-175mg/m2; arthralgia; myalgia; periph.
Taxol (antineoplastic/mitotic breast cancer(2nd Neuropathy; N/V; bradycardia;
38 paclitaxel IV duration depends hypotension;
inhibitor) line); lung
on dx myleosuppresion/neutropenia;
cancer(in combo); anaphylaxis; hypersensitivity
ovarian cancer(1st
line)
infection(methicilli
n resis
staphylococci; S.
epidermis;
Streptococcous
viridins; S.bovis; IV=2g/day divided
Vancocin entercoccus 6-12 hr; oral = 1/2- N/V; redman/neck syndrome;
39 vanomycin cap/IV ototoxicity; nephrotoxicity;
(antibiotic/glycoprotein) faecalis); 2g q6-8hrx7- neutropenia; anaphylaxis
endocarditis; 10days
Pseudomembranou
s colitis;
streptococcal
colitis;
diptheroidal

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

oral=100mg 1-2 hrs


prior; IV
chemo=1.8mg/kg blurred vision; dizziness;
chemo-induced drowsiness; fatigue; fever; chills;
Anzemet (antiemtic; serotonin 30min prior; HA; increase liver enzyme;
40 dolasetron tab/IV N/V; postoperative prutitis; sleep disorder; urinary
receptor antagonist) postop=12.5mg
N/V retention; arrhythmia;
15min before hypotension
removal anesthesia
or at onset

severe fungal
Abelcet; Ambisome anemia; chills; fever; N/V/D;
infection
(antiinfective; systemic 5mg/kg/day x2 dyspnea; hypoK; hypotension;
41 amphotericin B oral susp/IV susp refractory/intolera anaphylaxis(rare); multiple organ
antifungal; antiprotozoal; wks+ failure; nephrotoxicity; resp.
nt to conventional failure
polyene antibiotic)
amphotericin B
asthenia; HA; ab pain; anorexia;
constipation; diarrhea; stomatits;
Avastin (antineoplastic; nausea; dyspnea; upper resp
humanized monoclonal antibody; colorectal 5mg/kg over 90min infection; epistaxis; exfoliative
42 bevacizumab IV dermatitis; proteinurea; arterial
vascular endothelial growth carcinoma every 2wks thrombosis; CHF; gastro
factor antagonist) perforation; hypertensive crisis;
nephrotic syndrome; wound heal
comps
acute coronary 0.4mcg/kg/min x minor bleeding; bradycardia;
syndrome 30mins; then dizziness; major bleeding;
43 Aggrastat tirofiban IV coronary artery dissection;
undergoing 0.1mcg/kg/min x thrombocytopenia
angioplasty 24-48hours
0.6 mg/kg; then
Zemuron (non-depolarizing intubation; skeletal injection pain; anaphylatic
44 rocuronium IV 0.01-0.012 rxn(rare); arrhythmia(rare); HTN;
neuromuscular blocker) muscle relaxation
mg/kg/min infusion hypotension; tachycardia(rare)

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

PO=800-1600mg
QD x3wks; then bradycardia; corneal deposits;
titrate down to 600- hypotension; malaise; fatigue;
800 mg QD N/V; constipation; anorexia;
periph. Neuropathy; photosens;
Cordarone; Pacerone (group iii ventricular x1mon; poor coord/gait; tremor; visual
45 amiodarone tab/IV disturb; arrhythmia; CHF;
antiarrhythmic) arrhythmias IV=15mg/min hepatotoxicity; pulm tox; shock;
x10min; 1mg/kg steven-johnson syndrome;
x6hr; 0.5mg/min thrombocytopenia; thyroid
abnorm
x18hr; then
0.5mg/min

infection(S.M.&C.
pneumoniae
S.aureus;
S.pyogenes;
H.influenzae; 400mg 1-10days
M.catarrhalis; depending type nausea; diarrhea; dizziness; HA;
vaginitis; hyper/hypoglycemia;
46 Tequin; Zymar (fluoroquinolone) gatifloxacin tab/IV/ eye gtt E.coli; infection;gttts=1q2 periph. Neuropathy; tendon
N.gonorrheae) hx2days; rupture; torsades de pointes(rare)
chronic bronchitis; 1QIDx5days
pneumonia; bact
conjuctivitis;
sinusitis; skin/skin
structure; UTI

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

0.3-
0.35mg/k+F45g IV
balance anesthesia
over 20-30 sec; full
supplementation; hicoughs; N/V; cough;
effect 2min; "oversedation"; HA; drowsiness;
induction general
Versed (anesthetic sed=0.25mg/kg 20- agitation; invol. Movements;
47 midazolam IV/IM; tab anesthesia; apnea; ↓tidal volume & resp rate;
adjunct/benzo/sedative/hypnotic) 30sec 1hr before; oxygen desaturation(esp child);
sedation of mech resp arrest (rare); cardiac arrest
intubated pts=0.05-
vent pts; sedation; (rare); hypotensive crisis
0.2mg/kg loading
amnesia
then 1-
2mcg/kg/min
acute liver failur;
acute nephrosis;
adult resp distress
burns= 5-25%until
syndrome; burns;
reach albumin
Albuminar-5; Albuminar-25 cardiopulm
2.5g/100ml; serious= hypersensitivity (chills;
48 (blood modifier/volume albumin human IV bypass; newborn fever; urticaria(rare))
HoP=200-300ml
expander) hemolytic dx;
25% sol; max
hypoproteinemia;
2g/kg/day
hypovolemic
shock; renal
dialysis

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 Drugs Used in Hospitals in 2004

S.aureus;
S.epidermidis;
group A beta-
hemolytic
streptococci;
S.pneumoniae;
N/V/D; thrombocytopenia;
E.coli; biliary tract mild=250-500mg
Ancef (1st generation leukopenia(rare);
49 cefazolin IV/IM infection; bone & Q8hr; mod/sev= pseudomembranous colitis;
cephalosporin) hepatoxicity; steven-johnson
joint; endocarditis; 0.5-1g Q6-8hr syndrome
genital;
perioperative
prophylaxis; resp
tract; skin/skin
struc infections;
UTI

acromegaly;
diarrhea & ab discomfort; constipation;
A= 50mcg TID;
flushing due to diarrhea; flatulence; nausea;
Sandostatin 100-500mcg TID; biliary tract abnorm; dizziness;
carcinoid tumor; HA; hyper/hypoglycemia;
50 (endocrine/metabolic/somatostati sevoflurane IV/SC/IM doses depend what hypothyroid; injection pain;
diarrhea assoc
n analogue) treating for & pancreatitis; arrhythmia;
w/vasoactive conduction abnorm; sinus
IV/SC/IM bradycardia; worsening CHF
intestinal peptide
tumor

* Listed by dollars sold as compiled by NDC Health and found on www.drugtopics.com


Top 50 OTC Products in 2004

Ingredient Common Brand * Indication Usual Dose Common Side Effects

ADULT Fever: 200-400 mg ORALLY


Q4-6H PRN (MDD 1200 mg/day);
Osteoarthritis,Rheumatoid arthritis:
1200-3200 mg/day ORALLY divided
in 3-4 doses Body fluid retention, Rash, Abdominal pain,
Constipation, Diarrhea, Dyspepsia,
fever,arthritis(r,o),pa PEDIATRIC 6 months-12 years old, 5- Heartburn, Nausea, Stomatitis, Vomiting,
1 ibuprofen Advil; Motrin Increased liver function test (up to
in,dysmenorrhea 10 mg/kg ORALLYQ6-8H PRN (MDD 15%),Dizziness, Headache, Somnolence,
4 doses/day); 12 years and older, 200- Tinnitus
400 mg ORALLY Q4-6H PRN (MDD
1200 mg/day); Juvenile rheumatoid
arthritis: 30-50 mg/kg/day ORALLY in
3-4 divided doses; MAX: 2.4 g/day

ADULT Fever: 650-1000 mg


ORALLY Q4H PRN (MDD 4 g/day)
PEDIATRIC Fever: 10-15 mg/kg/dose
ORALLY Q4-6H (MDD 5 doses/day);
age 6-12 yrs: 325 mg ORALLY Q4-6H
acetaminophen Feverall; Tylenol fever,pain (MDD 2.6 g/DAY); Pain (Mild to rash, hypothermia
Moderate): 10-15 mg/kg/dose
ORALLY Q4-6H (MDD 5 doses/day);
Pain (Mild to Moderate): age 6-12 yrs:
325 mg ORALLY Q4-6H (MDD 2.6
2 g/day)

allergic
rhinitis,common
cold,fever,HA,inso 1 ta or cap PO hs or as directed by a
acetaminophen/diphenhydramine Tylenol PM mnia,mild physician. drowsiness
pain,myalgia,pruritu
s,rhinorrhea,sneezin
g

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

3 omeprazole Prilosec OTC ulcer,GERD 20 mg po qd rash,constipation, diarrhea, nausea,ha

Smoking cessation assistance: ORAL


inhaler, (on wk 1-12) 6-16
cartridges/day, (on wk 13-24) titrate to
lower dose, then off; MAX 16
cartridges/day
Smoking cessation assistance: NASAL
spray, (wk 1-8) 1 spray in each nostril
1-2 times/hr, at least 8 times/day; (wk
9-14) gradually taper over 4-6 wk;
MAX 5 times/hr, 40 times/24 hr
Commit; Nicoderm CQ; Smoking cessation assistance: skin & nasal & oral
4 nicotine smoking cessation TRANSDERMAL patch, smoking irritation,withdrawl,dizziness,ha,insomnia
Nicorette
history over 10 cigarettes/day: one 21
mg patch/day for 4-6 wk, then use one
14 mg patch/day for 2 wk, then use one
7 mg patch/day for 2 wk
Smoking cessation assistance:
TRANSDERMAL patch, smoking
history 10 or fewer cigarettes/day: use
one 14 mg patch/day for 6 wk, then use
one 7 mg patch/day for 2 wk

Fever,pain (minor) over-the-counter


dosing, 200 mg ORALLY every 8 to 12
edema,
hours as needed; do not take longer palpitations,rash,GI,anemia,dizziness,ha,vert
5 naproxen Aleve pain, fever than 10 days unless directed by igo,tinnitus,dyspnea
physician

allergic rhinitis, Adult, 25-50 mg po q4-6


insomnia,motion Pediatric <6 6.25-12.5 mg q 4-6, >6- dizziness,dyskinesia,sedated,somnolence,dry
6 diphenhydramine Benadryl; Sominex nose and throat,sputum
sickness,parkinsonis 12, 12.5-25 mg q 4-6
m,hives

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Adult Allergic asthma: 10-20 mg


ORALLY once daily for 3 days to 8
weeks
Allergic rhinitis & urticaria: 10 mg
ORALLY once daily
allergic rhinitis,
loratadine Alavert; Claritin idiopathic urticaria Pediatric Allergic rhinitis,urticaria: (2- HA, somnolence, fatigue
-chronic 5yrs) 5 mg ORALLY once daily,
allergic rhinitis,urticaria (>6 yr) 10 mg
7 Allergic asthma: 10-20 mg ORALLY
once daily based on body weight: 10
mg if less than 30 kg; 20 mg if greater
than 30 kg

Asthma: 5/120 mg, 1 tablet ORALLY


twice daily
seasonal allergic dizziness,ha,insomnia,somnolence,nervousne
loratadine/pseudoephedrine Claritin-D Seasonal allergic rhinitis: 5/120 mg, 1 ss,fatigue
rhinitis tablet ORALLY twice daily or 10/240
mg, 1 tablet ORALLY once daily
pain, fever, pain, fever- 325-650 q 4 prn, mdd 4g,
8 aspirin (acetylsalicylic acid) Bayer; Excedrin; Ecotrin cardio health- 81mg,arthritis- 3g
dyspepsia,n&v
arthritis,angina
Adult, GERD,esophagitis- 20-40 mg
BID, ucler maintenance- 20 mg hs
Pediatric- Gastroesophageal reflux
esophagitis,GERD,u disease: (1-16 yrs) 1 mg/kg/day
famotidine Pepcid AC lcer,hyperchlorhydri ORALLY divided twice daily up to 40 constipation, diarrhea, dizziness
mg twice daily
a Gastrointestinal ulcer: (1-16 yrs) 0.5
9 mg/kg/day ORALLY at bedtime or
twice daily up to a maximum of 40
mg/day;

relieves heartburn
famotidine/calcium associated with acid
Pepcid Complete chew 1 tablet,mdd2 constipation, flatulence
carbonate/magnesium hydroxide indigestion and sour
stomach

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

relieves heartburn
associated with acid skin rash, pruritus, diarrhea,N &
10 ranitidine Zantac 400 mg bid V,constipation
indigestion and sour
stomach
diarrhea, travelers
11 bismuth Pepto-Bismol diarrhea prevention, 525mg 30m-1 hr, mdd 4.2 g GI
h pylori infection
LAXATIVE, granules, oral: 1 to 2
constipation,anal rounded teaspoons (6 grams per
12 psyllium Metamucil fissures,hemorrhoids teaspoon) in the evening and/or before abdominal distention, flatulence
,IBS breakfast

Indicated for the


symptomatic relief
of hyperacidity
associated with the
13 calcium carbonate Caltrate; Tums diagnosis of peptic chew 2-4 prn constipation, flatulence
ulcer, gastritis,
peptic esophagitis,
gastric hyperacidity,
and hiatal hernia

Adult- Cough, Expectorant:


liquid/syrup/immediate-release, 200-
400 mg ORALLY every 4 hours
Cough, Expectorant: sustained-release,
600-1200 mg ORALLY every 12 hours
Cough, Expectorant: maximum dose,
2400 mg/day

14 guaifenesin Robitussin cough expectorant N/V

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Pediatric- Cough, Expectorant: (6-


12yrs) liquid/syrup, 100-200 mg
ORALLY every 4 hours
14 guaifenesin Robitussin cough expectorant Cough, Expectorant: (6-12yrs) N/V
maximum dose, 1200 mg/day
Cough, Expectorant: (2-6yrs)
liquid/syrup, 50-100 mg ORALLY
every 4 hours
Cough, Expectorant: (2-6yrs)
maximum dose, 600 mg/day
Cough, Expectorant: (under 2yrs) dose
should be individualized, common
dosage is 25-50 mg ORALLY every 4
hour
Cough, Expectorant: (under 2yrs)
maximum dose, 300 mg/day

sinus pain, ha, nasal


apap/pseudoephedrine Tylenol Sinus Day
and sinus congestion

nasal congestion,
nervousness
sinus pressure, sinus
apap/doxylamine/pseudoephedrin pain,ha, runny
Tylenol Sinus Night
e nose,sneezing, itchy
15 watery eyes,itching 2 every 4-6 hrs,mdd 8
nose/throat

minor aches and


pains, sinus ha,nasal
apap/guaifenesin/pseudoephedrin congestion,promotes
Tylenol Sinus Severe nervous, dizzy, sleepless
e nasal/sinus
drainage,loosen
mucus

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Allergic rhinitis: SR 120 mg ORALLY


every 12hrs (alone or in combination
with an antihistamine)
allergic rhinits,nasal Nasal congestion: 60 mg ORALLY htn, tachycardia,
16 pseudoephedrine Sudafed every 4-6hrs to maximum of 240 insomnia,anxiety,nervous,restless
congestion
mg/day or SR 120 mg ORALLY every
12hrs

17 docosanol Abreva herpes labialis apply 5 times a day until lesions healed application site reaction, ha

Adult 4 mg followed by 2mg up to


16mg/day
Pediatric Diarrhea, acute: (2-5 yr, 13 to
diarrhea, travelers 20 kg) 1 mg ORALLY 3 times daily
loperamide Imodium Diarrhea, acute: (6-8 yr, 20 to 30 kg) 2
diarrhea mg ORALLY twice daily
hyperglycemia,abdominal
18 Diarrhea, acute: (8-12 yr, greater than pain,N&V,dizziness,somnolence,fatigue
30 kg) 2 mg ORALLY 3 times daily

diarrhea,
take 2 with water after first loose stool,
loperamide/simethicone Imodium Advanced bloating,pressure,cra then 1 if needed, mdd4
mps (gas)
bacitracin/polymyxin B Polysporin antibacterial apply small amount 1-3 x daily rash
19
neomycin/polymixin B/bacitracin Neosporin antibacterial apply small amount 1-3 x daily rash

Candidal vulvovaginitis: 200 mg


VAGINALLY at bedtime for 3 days
Candidal vulvovaginitis: 100 mg
candidal VAGINALLY at bedtime for 7 days
Candidal vulvovaginitis: 1200 mg
vulvovaginitis,tinea
20 miconazole Desenex; Monistat VAGINALLY once N&V, vaginal discomfort
coroporis,cruris,pedi Tinea corporis,Tinea cruris,Tinea pedis:
s apply TOPICALLY to affected areas
twice daily
:
:

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

arhtritis, diabetic
21 capsaicin Icy Hot; Zostrix neuropathy,postherp apply thin film 3-5x day irritation, burning, stinging,erythema
etic neuralgia
Constipation: 5-15 mg ORALLY once
constipation, prep daily up to 30 mg/day, pediatric (6-
22 bisacodyl Dulcolax 11yrs) 5 mg once daily
GI
for bowel procedure

allergic
Coricidin HBP Cold & rhinitis,ha,mild/mod
acetaminophen/ chlorpheniramine 2 po q 4 hrs,mdd 8 rash
Flu erate,
rhinorrhea,sneezing

23 allergic
rhinitis,common
acetaminophen/chlorpheniramine/
cold, cough,
dextromethorphan/pseudoephedri Theraflu Severe Cold every 4-6 hours nervous, dizzy, sleepless
fever,ha,mild
ne
pain,congestion,rhin
orrhea, sneezing
aspirin/citric acid/sodium dyspepsia,ha,mild 1-2 tabs dissolved in 120 mls q 4-
24 Alka-Seltzer 6,mdd8
bicarbonate pain,myalgia
arthalgia,bursitis,mil
25 methylsalicylate BenGay d pain, apply 3-4 xday
myalgia,tendinitis

Dry mouth, dizziness, headache, heartburn,


loss of appetite, altered taste sensation,
start with one inhalation, then wait 1 restlessness, anxiety, nervousness, trembling,
26 epinephrine Primatine Mist $14.29 asthma minute. If not relieved, use once more. Inform your doctor if you experience: chest
Do not use again for at least 3 hours. pain, pounding heartbeat, breathing
difficulties.

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Side effects that you should report to your


prescriber or health care professional as soon
as possible:
•bloody or black, tarry stools
•confusion, excitement, restlessness, a false
sense of well-being
•eye pain, decreased or blurred vision, or
bulging eyes
•fever, sore throat, sneezing, cough, or other
signs of infection, wounds that will not heal
•frequent passing of urine
•hallucinations (seeing and hearing things
that are not really there)
•increased thirst
•irregular heartbeat
•menstrual problems
•mental depression, mood swings, mistaken
feelings of self-importance or of being
mistreated
Temporarily relieves •muscle cramps or weakness
itching associated •nausea, vomiting
•pain in hips, back, ribs, arms, shoulders, or
with minor skin Apply to affected area not more than 3 legs
27 hydrocortisone Cortizone; Preparation H •rounding out of face
irritations, to 4 times daily.
•skin problems, acne, thin and shiny skin
inflammation and •stomach pain
rashes •swelling of feet or lower legs
•unusual bruising, pinpoint red spots on the
skin
•unusual tiredness or weakness
•weight gain

Side effects that usually do not require


medical attention (report to your prescriber
or health care professional if they continue
or are bothersome):
•diarrhea or constipation
•headache
•increased appetite
•increased sweating
•nervousness, restlessness, or difficulty
sleeping
•upset stomach
•unusual increased growth of hair on the face
or body

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Side effects that you should report to your


prescriber or health care professional as soon
as possible:
•anxiety or panic reactions
•black, tarry stools
•confusion
•decrease in amount of urine passed
•difficulty breathing, wheezing
•dizziness, drowsiness
•fast or irregular breathing or heartbeat
(palpitations)
•fever or sore throat
•lightheadedness or fainting spells
•muscle twitching
•nausea, vomiting
•not willing to eat
•pain on swallowing
Adults: take 2 geltabs with a glass of •ringing in the ears
water. If symptoms persist or worsen, •seizures (convulsions)
ask your doctor. Do not take more than •skin rash or hives
28 acetaminohen/aspirin/caffeine Excedrin Migraine $4.19 Treats migraine. 2 geltabs in 24 hours, unless directed by
•stomach cramps and pain
•trembling
a doctor. Under 18 years of age: ask a •unusual bleeding or bruising, red or purple
doctor. spots on the skin
•unusual tiredness or weakness
•vomiting up blood, or what looks like coffee
grounds
•yellowing of the skin or eyes

Side effects that usually do not require


medical attention (report to your prescriber
or health care professional if they continue
or are bothersome):
•diarrhea
•frequent passing of urine
•headache
•nausea, vomiting
•nervousness, restlessness
•stomach gas, heartburn, or mild upset
stomach

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Relieves bloating, Swallow 1 or 2 softgels as needed after


pressure or fullness a meal. Do not exceed 2 softgels per There are no reported side effects with
29 simethicone Gas-X ; Phazyme day except under the advice and simethicone.
commonly referred supervision of a physician.
to as gas.

Relieves: heartburn,
sour stomach, acid ROLAIDS is generally well tolerated.
indigestion, upset Chew 2 to 4 tablets, hourly if needed. Constipation or stomach cramps may occur.
30 calcium/magnesium Rolaids Tell your doctor immediately if any of these
stomach due to these serious side effects occur: loss of appetite,
symptoms. vomiting, dizziness, headache.

Stinging, burning, sneezing, increased nasal


discharge, drying of the nostrils, and altered
Temporarily relieves 2 to 3 sprays in each nostril not more taste may occur.Notify your doctor if you
Afrin 12 hour; develop a rapid or pounding heartbeat,
31 oxymetazoline nasal congestion often than every 10 to 12 hours. Do not dizziness, trouble sleeping, shaking of the
Neo-Synephrine 12 hour exceed 2 doses in any 24 hour period. hands, tremors or unusual weakness ,may
cause dizziness.

LAMISIL AT is an
antifungal used on For athlete's foot between the toes spray
the skin to treat skin twice a day (morning and night) for 1 burning, redness or irritation the first few
week or as directed by a doctor. For days as your body adjusts to the medication.
32 terbinafine Lamisil AT infections such as jock itch and ringworm spray affected Notify your doctor if your develop: swelling,
athlete's foot, jock area once a day (morning or night) for 1 oozing, blistering.
itch or ringworm. week

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

constipation, upset
stomach caused by
heartburn, acid
indigestion or sour
stomach; for peptic 1 to 2 tablespoonsful. Children 6 to 11 diarrhea. If diarrhea persists or worsens,
Phillips Milk of Magnesia ulcer, hiatal hernia years: 1/2 to 1 tablespoonful. Children inform your doctor. Notify your doctor if the
33 magnesium hydroxide under 6 years: ask a doctor. following effects occur: black/tarry stools or
(MOM) or other conditions rectal bleeding.
caused by excess
stomach acid; and to
prevent ulcers or
bleeding from
ulcers.

To regrow hair on
top of the scalp
If excessive amounts of ROGAINE are
(vertex only). Not Apply 1 mL with dropper or sprayer (6 absorbed through the skin, headache, nausea,
34 minoxidil Rogaine intended for frontal sprays) 2 times a day directly onto the vomiting, dizziness, change in heart rate or
scalp in the hair loss area. blood pressure, chest pain, swelling of hands
baldness or receding or feet, or fatigue may occur.
hairline.

2 teaspoonfuls every 12 hours, not to


Temporarily relieves exceed 4 teaspoonfuls in 24 hours.
cough due to minor Children 6 to under 12 years of age: 1
throat and bronchial teaspoonful every 12 hours, not to Dizziness, drowsiness, nausea, vomiting, or
Benylin; Delsym; exceed 2 teaspoonfuls in 24 hours. stomach ache, Notify your doctor if you
35 dextromethorphan irritation as may Children 2 to under 6 years of age: 1/2 develop chest pain, a rapid pulse,
Vicks Formula 44 nervousness or become confused while
occur with the teaspoonful every 12 hours, not to taking DELSYM.
common cold or exceed 1 teaspoonful in 24 hours.
inhaled irritants. Children under 2 years of age: consult a
doctor

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Take preferably at bedtime or as


directed by a doctor. Adults and
children 12 years of age or older:
Starting Dosage: 2 tablets once a day. diarrhea, nausea, vomiting, rectal irritation,
Relieves occasional Maximum Dosage: 4 tablets twice a stomach cramps or bloating. Notify your
constipation day. Children 6 to under 12 years:
doctor if you experience: rectal bleeding,
rapid heart rate, weakness, dizziness,
(irregularity). Starting Dosage: 1 tablet once a day. fainting, sweating, skin rash, unrelieved
36 senna Ex Lax; Senokot Maximum Dosage: 2 tablets twice a constipation. SENOKOT may cause the
Generally produces urine to turn pink, red or brownish in color.
a bowel movement day. Children 2 to under 6 years: Do not be alarmed. It is not harmful.
Starting Dosage: 1/2 tablet once a day. Prolonged, frequent or excessive use of
in 6-12 hours. Maximum Dosage: 1 tablet twice a day. laxatives may lead to dependency
Children under 2 years: Starting
Dosage/Maximum Dosage: ask a
doctor.

Cures most athlete's


foot, jock itch, and
ringworm. Relieves For athlete's foot and ringworm, use
itching, burning, daily for 4 weeks; for jock itch, use burning, stinging or redness when first
applied to the skin. This should disappear in
37 clotrimazole Lotrimin cracking, scaling daily for 2 weeks. If condition persists a few days as your body adjusts to the
and discomfort longer, ask a doctor. This product is not medication
effective on the scalp or nails.
which accompany
these conditions.

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Upset stomach, nausea, vomiting, heartburn,


headache, diarrhea, constipation, drowsiness,
and unusual fatigue may occur. If any of
these effects persist or worsen, notify your
doctor. Tell your doctor immediately if any
of these serious side effects occur: stomach
Temporarily relieves pain, swelling of the feet or ankles, ringing
in the ears (tinnitus). Tell your doctor
minor aches and immediately if any of these unlikely but
Take 1 caplet every 8 to 12 hours while
pains due to: symptoms last. Do not exceed 2
serious side effects occur: vision changes,
joint pain, muscle pain or weakness, easy
menstrual cramps, caplets in any 8- to 12-hour period. Do bruising or bleeding, persistent sore throat
muscle aches, not exceed 3 caplets in a 24-hour and fever. Tell your doctor immediately if
38 pamabrom/apap Midol period. Adults over 65 years: Do not
any of these highly unlikely but very serious
headache, backache. side effects occur: changes in amount or
Extended relief for take more than 1 caplet every 12 hours color of urine, yellowing of the eyes or skin.
unless directed by a doctor. Children If you notice any of the following unlikely
up to 12 hours. under 12 years: Ask a doctor. but serious side effects, stop taking MIDOL
CRAMP and consult your doctor or
Maximum strength. pharmacist immediately: black stools,
coffee-ground vomit, persistent
stomach/abdominal pain. An allergic
reaction to MIDOL CRAMP is unlikely, but
seek immediate medical attention if it
occurs. Symptoms of an allergic reaction
include: rash, itching, swelling, dizziness,
trouble breathing.

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

May cause drowsiness, dizziness, headache,


loss of appetite (less likely with
nasal congestion, Do not take more than 4 doses in any cyproheptadine), stomach upset, vision
runny nose; 24-hour period. Adults and children 12
changes, irritability, dry mouth and nose.
These effects should subside as your body
brompheniramine/pseudoephedri sneezing; itchy, years and over: 4 tsp every 4 hours. adjusts to the medication. If they persist or
39 Dimetapp Cold & Allergy become bothersome, inform your doctor.
ne watery eyes; itching Children 6 to under 12 years: 2 tsp Notify your doctor if you develop: breathing
of the nose or throat; every 4 hours. difficulties, pounding or irregular heartbeat,
ringing in the ears, difficulty urinating. If
you notice other effects not listed above,
contact your doctor or pharmacist.

Stinging, burning, sneezing, increased nasal


discharge, drying of the nostrils, and altered
taste may occur. If these effects continue or
cough ,Helps loosen Adults and children 12 years and over: become bothersome, inform your doctor.
Coricidin HBP Chest
phlegm (mucus) and 1 or 2 softgels every 4 hours; not more Notify your doctor if you develop a rapid or
dextromethorphan/guaifenesin Congestion & Cough; than 12 softgels in 24 hours. Children
pounding heartbeat, dizziness, trouble
thin bronchial sleeping, shaking of the hands, tremors or
Robitussin DM under 12 years of age: ask a doctor. unusual weakness while taking CORICIDIN.
secretions CORICIDIN may cause dizziness. Use
caution engaging in activities requiring
alertness.

40

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Temporarily relieves
40 cough due to minor
throat and bronchial
Irritation and nasal Do not exceedperiod.
6 doses in a 24-hour
congestion as may Adult Dose: 2 teaspoonfuls every 4 hrs. Mild dizziness, mild drowsiness, headache,
occur with a cold. Child Dose: 6yrs. to under 12yrs. loss of appetite, nausea, dry mouth or
dextromethorphan/guaifenesin/ nervousness may occur. Notify your doctor if
Robitussin CF Helps loosen 1 teaspoonful every 4 hours. you develop: chest pain, rapid pulse, skin
pseudoephedrine 2yrs. to under 6yrs.
phlegm (mucus) and rash, painful or difficult urination, tremors,
1/2 teaspoonful every 4 hrs. extreme nervousness, trouble sleeping.
thin bronchial Under 2-Consult Your Doctor.
secretions to make
coughs more
productive.

CITRUCEL is generally well tolerated.


Bloating, gas, and a feeling of fullness may
Relieves occur. If these effects continue or become
41 methylcellulose Citracel constipation One scoop up to 3 times a day. bothersome, inform your doctor. Notify your
doctor if you experience: stomach cramps,
(irregularity). nausea, vomiting, rectal bleeding, unrelieved
constipation.

Calcium
Supplement:
Antacid/Antigas: nausea, loss of appetite, constipation or
Calcium Supplement: Chew 2 tablets
For the relief of acid twice diarrhea, weakness, or headache.Notify your
aluminum/magnesium Maalox daily. Antacid/Antigas: Chew 1 doctor if you notice black, tarry stools while
indigestion, to 2 tablets as symptoms occur taking MAALOX.
heartburn, sour
42 stomach, upset
stomach

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
42 Top 50 OTC Products in 2004

Relieves bloating, Take 1-2 softgels as needed after meals generally well tolerated. Notify your doctor
aluminum/magnesium/simethicon if you develop: loss of appetite, vomiting,
Mylanta pressure, and and at bedtime. Do not exceed 4 dizziness, headache. Constipation and
e softgels per day
discomfort of gas stomach cramps may occur.

relief of burning and


irritation due to sting or burn, blurred vision. Notify your
dryness of the eye; Put 1 or 2 drops in the affected eye(s) doctor if you develop: skin rash, eye pain,
43 tetrahydrozoline Visine as needed. swelling in or around the eyes, vision
for protection problems.
against further
irritation.

hay fever or other drowsiness, dizziness, headache, loss of


upper respiratory appetite (less likely with cyproheptadine),
allergies: sneezing; 1 tablet every 4 to 6 hours, not to stomach upset, vision changes, irritability,
chlorpheniramine Chlor-trimeton exceed 6 tablets in 24 hours.
dry mouth and nose. Notify your doctor if
runny nose; itchy, you develop: breathing difficulties, pounding
watery eyes; itching or irregular heartbeat, ringing in the ears,
difficulty urinating.
of the nose or throat.

coughs, runny nose


and sneezing due to Stinging, burning, sneezing, increased nasal
44 chlorpheniramine/dextromethrop Coricidin HBP Cough & the common cold. 1 tablet every 6 hours, not more than 4
discharge, drying of the nostrils, dizziness,
Notify your doctor if you develop a rapid or
Decongestant-free tablets in 24 hours pounding heartbeat, dizziness, trouble
han Cold
cold relief for sleeping, shaking of the hands, tremors or
unusual weakness while taking CORICIDIN.
people with high
blood pressure.

sneezing; itchy nose


or throat; runny Dizziness, headache, loss of appetite,
chlorpheniramine/pseudoephedrin nose; itchy, watery Take every 4 to 6 hours; not more than nausea, nervousness or insomnia Notify your
Triaminic Cold & Allergy 4 doses in 24 hours
doctor if you develop chest pain, a rapid
e eyes due to hay pulse, skin rash, high blood pressure,
fever; nasal and tremors, or nervousness

sinus congestion.

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

drowsiness, dizziness, headache, loss of


appetite (less likely with cyproheptadine),
For prevention and stomach upset, vision changes, irritability,
1 to 2 tablets every 4-6 hours; not more
45 dimenhydrinate Dramamine treatment of nausea, than 8 tablets in 24 hours
dry mouth and nose. Notify your doctor if
you develop: breathing difficulties, pounding
vomiting, dizziness. or irregular heartbeat, ringing in the ears,
difficulty urinating.

Relieves occasional stomach ache, cramping or irritated throat


constipation Adults and children 12 years and over: (liquid forms). Notify your doctor if you
take 1-6 capsules daily. Children 2 to experience: skin rash, rectal bleeding, lack of
(irregularity). bowel movements. Frequent use of laxatives
46 docusate Colace under 12 years of age: take 1-3 capsules can cause dehydration and loss of essential
Generally produces daily. Children under 2 years: ask a nutrients. Symptoms include muscle cramps,
bowel movement in doctor. muscle weakness or dizziness. Maintain an
12 to 72 hours. adequate fluid intake while using COLACE.

Helps to reduce May cause drowsiness, dizziness, headache,


loss of appetite, stomach upset, vision
difficulty in falling 1 softgel (50 mg) at bedtime if needed, changes, irritability, dry mouth and nose.
47 doxylamine Unisom or as directed by a doctor. Notify your doctor if you develop: breathing
asleep. Safe. Proven difficulties, pounding or irregular heartbeat,
effective. ringing in the ears, difficulty urinating.

one hour before travel starts. take 1 to May cause drowsiness, blurred vision,
48 meclizine Bonine motion sickness. 2 tablets once daily stomach upset, headache or dry mouth.

Reduce Recommended daily dosage of COLD-


EEZE Cold Remedy Lozenges is 6
49 zinc salts Cold EEZE duration/severity of drops per day (79.8 mg zinc).
caused anosmia, the permanent loss of smell
common cold top

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 50 OTC Products in 2004

Temporary relief of
itching and pain temporary redness or minor irritation when
associated with Apply to affected area not more than 3 first applied. Notify your doctor if you
50 calamine/pramoxine Caladryl to 4 times daily. develop: swelling/itching/rash where the
rashes; dries medication was applied.
oozing/weeping

* * ranked by dollar sales as compiled by Information Resources, Inc. and found on www.drugtopics.com
Top 30 Common Herbals/Dietary Supplements

Ingredient Indication Usual Dose Side Effects Drug Interactions


1. prevention & treatment adults=1-10 billion in 3-4
of diarrhea doses; 5-10 billion in 3-4 flatulence; rare bactermia antibiotics (separate by 2h);
1 Acidophilus immunosuppressants
(antibiotic/traveler's/IBS) doses dissolved in & septicema
2. atopic dermatitis rehydration liquid

1.improved congnition insomnia; vaginally


2.↓fasting BG in type 200-600mg/d extract 0.6- bleeding; abnormalities; warfarin=↑INR; caffeine=↑HTN;
antidiabetics=↓BG; ↑ effect;
2 Asian Ginseng 2DM 3.adaptogen 3g 1-3Xday root powder tachycardia; palpatation; stimulants=possibly ↑ effect;
4.immune fxn stimulation 100mg/d anorexia; diarrhea; HA; immunosuppressants=↓ effect
5.cancer prevention BP changes;

1.menopausal sx dried rhizome/root 300-


2.induce labor 2000mg TID liquid GI upset; HA; dizziness;
3 Black Cohosh none
3.PMS extract 0.3-2.0ml poQD weight gain; leg cramping
4.dysmenorrhea tincture 2-4ml poQD
1.DM 200-1000 mcg/day in HA; insomnia; mood iron=↓absorption; zinc=↓C
4 Chromium absorption; vit C=↑absorption
2.hypercholesterolemia divided dose changes

1.CHF
2.prevent cardiotoxicity
100mg BID or TID; 50
assoc w/doxorubicin chemotherapeutic
mg QD; 300,600,1200mg
3.huntington's dx well tolerated; most are agents=specifically alkylating
5 Coenzyme-Q10 in 4 divided dose; 200mg agents warfarin=↓ anticoagulation
4.parkinson's dx GI(<1%)
QD; 150-160 mgQD or effects
5.stimulate HIV pt
2mg/kg/day
immune fxn
6.mitochondrial disorder

* Originally compiled by Drs. N. Allie, Brodeur, Grabe, Kane, Schreck, and Zeolla in March 2003. Edited by Dr. Audette in June 2005.
Top 30 Common Herbals/Dietary Supplements

1.UTI
generally well tolerated;
2.prevention urinary UTI preven=1-10oz
large doses induce GI
catheter blockage juice/day; DM=6 caps cyp450 2c9 substrates=
6 Cranberry upset & diarrhea; long ↓metabolism; warfarin=↑INR
3.DM type 2 (240ml juice equiv)/day
term causes uric acid
4.scurvy for 12 wks
kidney stone
5.antipyretic

oral=3-4g divided dose anticoagulants=↓effect;


1.menopausal sx bleeding; brusing;
7 Dong Quai w/meals extract=1ml ginko/ginger/garlic/ginseng=↑blee
2.vasodilators photosensitivity; ding time
TID
1.prevention & treatment GI upset; dizziness; immunosuppressants=↓ effect;
extract=6.78 mg or 2 tabs
8 Echinacea common cold & flu dyspnea; pruritis; 3A4 inhibition=lovastatin;
TID; 6-9ml/day for 8 wks ketoconazole, ect
2.immuno-stimulant hypersensitivity
1.PMS anesthesia=seizure;
well tolerated; rare nocturnal
9 Evening Primrose 2.endometriosis 3-4 g po QD anticoagulants=may seizure; pregnancy complications
3.menopause sx ↑bleedin

CI in children <2y &


migraine=dried pwd or pregnancy; oral
capsule ulceration; tongue antiplatelet/anticoag=↑ bleeding;
1.migraines NSAIDS=↓ effect; iron=↓
(standardized)125-250mg irriation; ab pain; N/V/D;
10 Feverfew 2.rheumatoid arthritis absorption; cross-allergy
po QD; general use=(leaf) "post-feverfew syndrome" (ragweed/chrysanthemums
3.menstrual irregularities
1-3 leaves chewed daily (nervousness; tension; /marigold/daisies)
w/food HA; insomnia; joint pain;
fatigue); derm rxn

1.hypertriglyceridemia
2.RA
approx 3-4 grams/day GI- belching; N/D; heart anticoagulants= ↑effect; vit E=↓vit
11 Fish Oil (Omega-3) 3.HTN E levels
(upto 6 gm/d) burn
4.psorisis
5.CV risk

* Originally compiled by Drs. N. Allie, Brodeur, Grabe, Kane, Schreck, and Zeolla in March 2003. Edited by Dr. Audette in June 2005.
Top 30 Common Herbals/Dietary Supplements

1.hyperlipidemia
15-30ml/day;
12 Flaxseed Oil 2.laxative 3.EFA diarrhea; allergic rxn anticoag/antiplat=↑ effect
(>30gm/day)
source

general use= (pwd)


900mg po QD; (raw) 4g
1.dyslipidemia
po QD; BV clot=600- breath odor; GI upset; ↓
2.HTN protease inhib=↓ saquinavir [ ] by
13 Garlic 800mg po QD; platelet aggregation; derm 50%; antiplat/anticoag=↑ bleeding
3.atherosclerosis/antioxi
dyslip=600-900mg po rxn; spermatogenesis inhib
4.antibiotic
QD; HTN=200-300mg po
TID

1.motion sickness
2.morning sickness 500-2000mg dried pwd ab discomfort; heartburn; anticoag/antiplat= theoretical risk
(inhibition); BP
14 Ginger 3.vertigo root in 3-4 times/day; or diarrhea; pepper-like antidiabetic/cardiac meds=may
4.others (OA, migraine, 1g 1-4hrs prior to travel irritation; interfere w/effect of each
post-op N/V)

120-240mg/day in anticoag/antiplat=↑ bleeding;


1.alzhemier dx
divided doses leaf extract; GI upset; HA; dizziness; anticovulsant= ↓effect/↑seizure
15 Gingko Biloba 2.memory improvement risk; antidiabetic=possibly ↓
upto 600mg/day used for ↑bleeding risk
3.tinnitus effect/↑ BG levels
mem improvement

GI=nausea; heartburn;
1500mg po QD or in 3 antidiabetics=may ↑ insulin
1.osteoarthritis 2.TMJ diarrhea; constipation;
16 Glucosamine / Chondroitin doses (OA); 500mg TID resistance/↓ production; etoposide
arthritis caution in patients with and doxorubicin
(TMJ)
shellfish allergy
1.prevention of
dried root/tea=0.5-1g b-vits=↓ absorption;
infection/GI disorder GI upset; hallucination;
17 Goldenseal TID; mouthwash=2 tsp in PPI/H2RA/antacid= ↓ effect;
2.mouthwash & eyewash delirium; ↓BP; skin ulcer sedative= ↑ effect; inhibit 3A4
150 ml TID-QID
for inflammed tissue

* Originally compiled by Drs. N. Allie, Brodeur, Grabe, Kane, Schreck, and Zeolla in March 2003. Edited by Dr. Audette in June 2005.
Top 30 Common Herbals/Dietary Supplements

1.antioxidant 2.venous
18 Grapeseed 150-300mg/day some hepatotoxicity warfarin= ↑ bleeding risk
insufficiency
1.improved cognitive fxn dyspepsia; flatulence; caffeine/cimetidine=↑ ADR;
2.GI disorder nausea; vomiting; iron=↓ absorption;
240-320mg polyphenols warfarin=↓effect; CNS
19 Green Tea Extract 3.headache agitation; dizziness;
(3 cups tea) depressents=↓effect;
4.cancer insomnia; tremors; antiplat=↑effect; lithium= abrupt
5.hypercholesteremia restlessness withdrawal↑ levels

CI=pregnancy/lactation;
general use= (dried GI disturbances; digoxin=↑toxicity risk;
fruit)=0.3-1g or tea TID palpitation; HA; dizziness; vasodilator= additive effect; cardio
20 Hawthorne 1.heart failure
po; HF=12-15mg divided sleeplessness; agitation; med= may enhace/interfere others;
TID po x6 wks bronchospasm; chest pain; CNS depress=additive effect
derm rxn

1.symptomatic tx chronic avoid oral ingestion of raw anitcoag/antiplat=↑ bleeding risk;


21 Horse Chestnut venous insufficiency 300mg seed extract BID; bark/leaf; itching; GI antidiabetic=possibly ↑ effect/↓
(varicose vein) irritation; hypersens BG levels

1.insomnia
2.jet lag
1&2=0.3-5mg qHS; INH/immunosup/BDZ=↑ effect
3.BDZ & nicotine ↑HR; sedation; HA;
22 Melatonin 3=2MG qHS x6wks; BDZ; β-block/CCB=↓ effect of
withdrawal confusion; ↓BP; irritability BP; SSRI/steroid/TCA= ↓ effect
4&5=10-50mg QD
4.antioxidant
5.chemotherapy

general use=420mg cyp450 3a4 inhibition;


antidiabetic=↓ BG levels; cross-
1.hepato-protectant poQD of extract; 70-80% diarrhea; bronchospams;
23 Milk Thistle allergenticity=ragweed;
2.protect kidney divide TID x6-8 wks; chest pain; derm rxn chrysanthemums; marigolds;
maintain=280mg poQD daisies

* Originally compiled by Drs. N. Allie, Brodeur, Grabe, Kane, Schreck, and Zeolla in March 2003. Edited by Dr. Audette in June 2005.
Top 30 Common Herbals/Dietary Supplements

1.chronic pain
MSM
24 2.arthritis 1000-3000mg po QD GI; HA; pruritis; allergy none
(Methylsulfonylmethane)
3.joint inflammation

antidepres=additive serotonergic
1.depression flatulence; N/V/D; effect; dextromethorphan=possibly
2.heart disease constipation; dry mouth; additive sertonergic effects;
25 SAM-e 3.fibormyalgia 400-1600mg/day; HA; insomnia; anorexia; levodopa=↓ effect; meperidine=
4.osteoarthritis sweating; dizziness; additive sero effect;
MAOI=serotonin syndrome;
5.alzheimer's dx/dementia nervousness
tramadol=additive sero effect

anticoag/antiplat=↑ bleeding;
1.treatment sx BPH 160mg BID lipophilic rare=well tolerated mild
26 Saw Palmetto hormone tx=may interfere
2.treatment of alopecia extract 80-90% fatty acids GI intolerance w/effects

1.menopausal sx
constipation; bloating; antibiotics= ↓AB efficacy;
27 Soy Isoflavones 2.hyperlipidemia 3.OP 20-60 g/day tamoxifen= ↓ T efficacy
nausea; allergic rxn
prevention

triptan=serotonin syndrome;
insomnia; vivid dreams; antidep=↑ serotogenic; cyp3a4
1.depression 2.antiviral
28 St. John's Wort 300 mg TID anxiety; GI disturbance; inducer==↓ CBZ; cyclosporine;
3.OCD NNRTI; oral contracept; protease
photoderm
inhib; digoxin; theophyl

1.acne/onychomycosis confusion; inability to


5-25-100% topically BID
29 Tea Tree Oil 2.ring worm & walk; disorientation; none
x6mo
scabies 3.athlete's foot ataxia; dermatitis
alcohol/barb/BDZ= ↑ sedation;
1.sedative-hypnotic 400-900mg 2h a HS or long term=BDZ
30 Valerian cyp450 3A4 (↑ lovastatin; ketocon;
2.insomnia 300-450mg/day TID withdrawal syndrome triazolam; ect)

* Originally compiled by Drs. N. Allie, Brodeur, Grabe, Kane, Schreck, and Zeolla in March 2003. Edited by Dr. Audette in June 2005.

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