Anterior Uveitis Moderate uveitis: Pred forte 1 gtt q1h.

in cases of inc IOP, Rx aqueous suppressants (beta blocker, alpha agonists, no anti-miotics). If steroid doesnt produce change in gr 3+ over 3 days, use periorbital injection or Prednisone PO 60-max 80mg (or 1mg/kg). Drug-induced uveitis: systemically administered PO biphosphanates (tx osteoporosis) and topical metipranolol (beta blocker) and to a lesser extent, PO sulfonamides, rifabutin, topical glucocorticoids. Suspect idiopathic anterior uveitis until proven otherwise, esp for 20-40yo. Tx: Steroid, cycloplege. Recurrent anterior uveitis: suspect sarcoidosis until proven otherwise. Run ESR (elevated), CBC, CRP (elevated), ACE (angiotensin converting enzyme elevated), antinuclear antib, RF, VDRL/FTA-ABS.

Seronegative = negative for rheumatoid factor (RF) CCP can detect early RA even with neg RF.

Spondylarthropathies: inflammatory arthritis of the spine, sacroiliac and oter joints of the boey Enthesopathy: inflammation where the ligaments attach to bone Hereditary factor Absence of physical signs or testing markers that are found in other types of arthritis. 20-30yo, M>F except psoriatic arthritis. Almost never bilateral simultaneously.

Radiology: X-ray or CT scan only shows bone and structure. Bone scan involves radioactive dye in bone cells that have high turnover rate. Ankylosing spondylitis: Systemic tx: start with glucocorticoids, if no resolution then wean off and start DMARDs (methyltrexate), NSAIDs (not terribly effective). Reiters syndrome (***Boards loves this one) know the triad of signs, conjunctivitis can also be uveitis. Only the Extramusculoskeletal syndrome involves the eyes. Bilateral simultaneously. Joint/skin conditions. Probably not idiopathic uveitis when bilateral!!

Behcets Disease (*** Boards loves this one too) know cardinal signs. Mouth ulcers (aphthous stomatitis) heal quickly. Boards loves prick test.