Candidates are required to give their answers in their own words as far as practicable. The figure in the
margin indicates full marks.
Group A
Group B
Answer any six questions. Questions are of equal value. 6 × 7 = 42
1 Explain with examples the hydrophobic interaction.
2 Describe the role of genetic mutation in evolution.
3. Describe chemical composition of biological membranes.
4 Explain the differences between and prokaryotic and eukaryotic cells.
5 Derive Henderson – Hesselbach equation.
6. Describe the bicarbonate buffer system.
7. Determine the weight in grams of sodium dihydrogen phosphate (formula weight FW 138.01) and disodium
hydrogen phosphate ( FW 149.98 ) needed to prepare 1 liter of a standard buffer at pH 7.00 with a total phosphate
concentration of 0.100 M. ( pKa of dihydrogen phosphate = 6.86 and pKa of monohydrogen phosphate = 12.4 ).
8 In a hospital laboratory, a 10.0 ml sample of gastric juice , obtained several hours after a meal, was titrated with 0.1
M NaOH to neutrality; 7.2 ml of NaOH was required. The stomach contained no ingested food or drink, thus
assume that no buffers were present. What was the pH of gastric juice ?
Group – C
Answer any eight questions. Questions are of equal value. 8 × 2 = 16
1. Structure of ATP.
2. What is an open, isothermal system?
3. Different between tight junction and gap junction
4. Plasmids
5. Thylakoids
6. How the lysosomes provides a second line of defence against destruction of cytosolic macromolecules.
7. Stereospecificity
8. Enantiomers
9. Entropy
10. Structure of aspartic acid
11. Amphipathic compounds
12. Virions and bacteriophages.
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