DRUG STUDY

STUDENT NAME: GROUP 14 PATIENTS NAME: Melanie Silades DATE:

TRADE NAME
>Ponstan

GENERIC NAME
>Mefenamic Acid

INDICATIONS WHAT TYPE OF PROBLEMS >Short-term relief of mild to moderate pan inluding primary dysmenorrhea

SPECIFICACTIONS/ MECHANISM OF ACTIONS >Anthranilic acid derivative. Like ibuprofen inhibits prostaglandin synthesis and affects platelet function. No evidence that it is superior to aspirin.

SIDE EFFECT
>CNS: Drowsiness, insomia, dizziness, nervousness, confusion, headache. >GI: Severe diarrhea, ulceration, and bleeding; nausea, vomiting, abdominal cramps, flatus, constipation, hepatic toxicity. >Hematologic: prolonged prothrombin time, severe autoimmune hemolytic anemia(long-term use), leukopenia, eosinophilia, agranulocytosis, thrombocytopenic porpura, megaloblastic anemia, pancytopenia, bone marrow hypoplasia. >Urogenital: Nephrotoxicity, dysuria, albuminuria, hematuria, elavation of BUN. >Skin: Urticaria, rash,

CONTRA INDICATIONS
>Hypersensitivity to drug; GI inflammation, or ulceration. Safety in children<1/t y, during pregnancy(category C), or lactation is not established.

NURSING SPECIAL CONSIDERATION/NURSING IMPLICATIONS >Assess patients who develop severe diarrhea and vomiting for dehydration and electrolyte imbalance. >Lab test: with long-term therapy (not recommended) obtain periodic complete blood counts, Hct and Hgb, and kidney function test. >Discontinue drug promptly if diarrhea, dark stools, hematemesis, ecchymoses, epistaxis, or rash occur and do not use again. Contact physician. >Notify physician if persistent GI discomfort, sore throat, fever, or malaise occur. >Do not drive or engage in potentially hazardous activities until response to drug is known. It may cause dizziness and drowsiness. >Monitor blood glucose for loss of glycemic control if diabetic

facial edema. >Special Senses: Eye irritation, loss of color vision(reversible), blurred vision, ear pain> >Body as a Whole: Perspiration. >CV: Palpitation. >Respiratory: Dyspnea; acute exacerbation of asthma, bronchoconstriction(in patients sensitive to aspirin).