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ituRf;fs;
} } } } } }

kw;iwa %d;W tiff; fpUkpfspy; ,Ue;Jk; ituRf;fs; kpfTk; NtWgl;ljhFk;. ituRf;fs; Rthrpg;gNjh> cz;gNjh> foptfw;WtNjh> ,dg;ngUf;fNkh nra;tjpy;iy. ituRf;fs; capUs;s nghUl;fSf;Fk; capuw;w nghUl;fSf;Fk; ,ilapy; cs;s vspa mikg;ghFk;. ,it Gujf;$l;bdhy; Rw;wg;gl;l kugZf;fspdhyhd DNA my;yJ RNA iaf; nfhz;l vspa mikg;Gf;fshFk;. ,it ,dg;ngUf;fk; nra;tjw;F> Xh; capUs;s fyj;jpw;Fs; nrd;W mjd; rpy gFjpfis cs;nsLj;Jf; nfhs;Sk;. mjd; gpd;dNu ituR jd;Nghd;w gpujpfis cUthf;Fk;.

HIV
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HIV, .

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cq;fs; eph;g;gPldj; njhFjp cq;fs; cly; KOtJk; fhzg;gLk; ,urhadg; nghUl;fs;>fyq;fs;> ,ioaq;fs;> mq;fq;fs; Mfpad Nrh;e;j xU tiyg;gpd;dyhFk;. ,it fpUkpfspypUe;J cq;fisg; ghJfhf;f xd;whfj; njhopw;gLfpd;wd. cq;fs; clYf;Fr; nrhe;jkhdtw;wpw;Fk; nrhe;jk; my;yhjtw;wpw;Fk; cs;s NtWghl;bid cq;fs; eph;g;gPldj; njhFjpahy; fz;L nfhs;s KbAk;. cq;fs; clYf;Fr; nrhe;jky;yhjJ cq;fs; clYf;Fs; GFe;jhy;> cq;fs; cliy eyj;Jld; itj;jpUg;gjw;fhf cq;fs; eph;g;gPldj; njhFjp mjid mopj;Jtpl KaYk;.

HIV njhw;wpd; epiyfs;

HIV njhw;W } NrNuhnfhd;Ntrd } mwpFwpapy;yhj HIV njhw;W } mwpFwpfSs;s HIV njhw;W
} Muk;g

Muk;g HIV njhw;W

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,J> ePq;fs; Kjypy; HIV apdhy; njhw;wg;gl;l fhyj;ijf; Fwpg;gjhFk;. fLikahd njhw;W vd miof;fg;gLk; ,f;fhyj;jpy; ituR Ntfkhfg; ngUFk;. njhw;W Vw;gl;L ,uz;L njhlq;fp ehY thuq;fSf;Fg;gpd; ePq;fs; mnrsf;fpakhf - jbkd;> fha;r;ry; njhz;ilf;fug;gd;> tPq;fpa epzePh;f; fyq;fs;> jiyapb> grpapd;ik my;yJ Njhy; fug;gd; Nghd;wdtw;iw czuyhk;>

Muk;g HIV njhw;W

} }

} } }

,J rpy thuq;fSf;F ePbj;J ,Uf;fyhk;. ,e;jf; fhyj;jpy; cq;fs; T4 fyq;fspd; vz;zpf;if tPo;r;rpailayhk;. mj;Jld;> cq;fs; FUjpapy; iturpd; njhif kpff; $Ljyhfyhk;. ,e;epiyapy;> ePq;fs; HIV ,d; gpwnghUnsjphpfSf;Fg; ghpNrhjid nra;Ak;NghJ mit Njhw;wg;gl khl;lhJ. vdpDk; ituir NtW xUtUf;Ff; flj;jyhk;. ,f;fhy fl;lk; rhsuf; fhyk; vdg;gLk;. kpff; $Ljyhd mstpy; njhw;wpid Vw;gLj;jf;$ba fhyk; ,J.

NrNuhnfhd;Ntrd; Seroconversion
} NrNuhnfhd;Ntrd;

vdg;gLtJ HIV f;F gpwnghUnsjphpfis cz;lhf;Fk; epiyiaf; Fwpf;Fk; nrhy;yhFk;. } ,e;epiy njhw;wpd; gpd; xd;wpypUe;J %d;W khjq;fs;tiu ePbf;Fk;. } ,jd;gpd; gpwnghUs; vjphpf;Fhpa ghpNrhjid nra;Ak;NghJ> mit NeNuw;wkhf (positive) ,Uf;Fk;

mwpFwpapy;yhj HIV njhw;W

} } } } } } }

mwpFwpapy;yhj njhw;W vd;why; mwpFwpfs; ,y;yhjJ vd;gJ fUj;jhFk;. ,e;j epiy> ey;y jpUg;jpfukhd epiyapy; ePq;fs; ,Ug;gjhf czh;e;J gy Mz;LfSf;F ,Uf;fyhk;. vg;gbahapDk;> ,uz;L my;yJ $Ljyhd NtW gFjpfspy; (cjhuzj;jpw;F cq;fs; fOj;Jk; mf;Fs;fSk;) tPq;fpa epzePh;f; fZf;fs; Vw;glf;$Lk;. ,J persistent generalized lymphadenopathy vdg;gl;L> mJ khjq;fSf;F my;yJ rpyNtis Mz;LfSf;Fk; ePbf;fyhk;. cq;fSf;F ntspg;gilahd mwpFwpfs; ,y;yhjpUe;j NghjpYk;> cq;fs; T4 fyq;fspd; vz;zpf;if Fiwaj; njhlq;fyhk;.

mwpFwpfSs;s HIV njhw;W

} cq;fs;

eph;g;gPldj; njhFjp iturpdhy; gyaPdKw;W ,Uf;Fk; Ntisapy;> Njftpay;ghf my;yJ KO clyhy; HIV njhw;wpd; mwpFwpfs; mjpfhpf;fyhk;. } ,itfs;> tPq;fpa epzePh;f; fZf;fs;> ,uT tpah;it> fha;r;ry;> tapw;Nwhl;lk;> cly; epiw ,oj;jy;> fisg;G Mfpatw;Wld; mf;fp Nghd;w njhw;Wf;fs;> epue;ju ngz;Fwp <];w; njhw;Wf;fs;Yhf;Nfhgpshf;fpah MfpadthFk;.

Phases of Infection

vapl;]; (AIDS) vd;why; vd;d?

vd;w nrhy; Acquired Immune Deficiency Syndrome vd;w Mq;fpyr; nrhw;fspd; KjnyOj;Jf;fshFk;. } vapl;]; (AIDS) vd;w Neha; Vw;gLtjw;F vr;.I.tp HIV vd;w ituRf; fpUkpfs; jhd; fhuzk;.
} vapl;];

A-ACQUIRED - ngwg;gl;l
} } } } }

vr;.I.tp HIV vd;w ituRf; fpUkpfs; cq;fisg; Gwr; #oy;fspy; ,Ue;J jhd; njhw;wpf;nfhs;fpwJ. ,jdhy; ,J Gw ,lj;jpypUe;J ngwg;gl;ljhff; (ACQUIRED) $wg;gLfpd;wJ. HIV fpUkpfis mopf;Fk; ty;yik cq;fs; clYf;F ,y;iy. HIV fpUkpfs; njhw;wpf; nfhz;Ls;s xUtiu HIV+ vd;W miof;fg;gLk;. ,J guk;giu Mdjy;y vd;gijAk; Fwpg;gjhFk;.

I-IMMUNE Nehnajph;g;G
fpUkpfs; clypy; Nehnajph;f;Fk; rf;jpiaj; jhf;fp mopf;fpd;wJ. } Nehnajph;g;G rf;jpjhd; vk;ik gy;NtW fpUkpfspypUe;Jk;> Neha;fspypUe;Jk; ghJfhf;fpd;wJ. } Nehnajph;g;Gr; rf;jp eph;g;gPldk; vd;Wk; miof;fg;gLk;.
} HIV

D-DEFICIENCY - FiwghL
fhyk; HIV fpUkpfs; cq;fs; clypy; jq;Fk; nghOJ> Nehnajph;f;Fk; rf;jp gytPdkilfpd;wJ. } mjdhy; clYf;F Nkw;nfhz;L Neha;fis vjph;f;f Kbahky; Ngha;tpLfpd;wJ. } mjhtJ Nehnajph;f;Fk; rf;jp kpfTk; Fiwe;J tpLfpd;wJ.
} $ba

F A

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HIV-Infected T-Cell
HIV Virus T-Cell HIV Infected T-Cell New HIV Virus

 O H . . M, Jv

S-SYNDROME - gy Neha;fspd; ciwtplk;

Nehnajph;g;Gj; njhFjp kpfTk; gytPdkile;j gpd;G> gyk; Fd;wpa clyhdJ gytpjkhd fpUkpfSk;> Neha;fSk; jhf;ff;$ba xU ciwtplkhf khwptpLfpd;wJ. } vapl;]; vd;gJ xU jdp Neha; my;y> gy Neha;fspd; $l;lhFk;. } HIV njhw;Wf;fNshL T4 fyq;fspd; vz;zpf;iff; FiwT> kw;Wk; gy re;jh;g;gj; njhw;Wf;fs; Mfpatw;wpd; njhFg;G MFk;.
} clypd;

, . .

HIV in Body Fluids

Blood 18,000

Semen 11,000

Vaginal Fluid 7,000

Amniotic Fluid 4,000

Saliva 1

Average number of HIV particles in 1 ml of these body fluids

. . M,
} Sex

blood or blood products } Mother to baby } Use of needles and instruments without sterilization
} Infected

How does HIV enters the body ?

Injecting drugs

Probable Mode of transmission in Sri lanka

10%

4% 85% 1% 0%

[N=539, Data as of end 2005]

Heterosexual Homosexual Perinatal Blood IDU

HIV spread by blood transfusion

Mother to baby during pregnancy, birth and breast feeding

Sharing of needles by drug addicts

AIDS virus is not transmitted through hugging and hand shake

AIDS virus is not transmitted through sharing toilets and cough

AIDS virus is not transmitted through eating together, swimming pools

AIDS virus is not transmitted through sharing clothes, mosquito bites

AIDS virus is not transmitted through parent caring

.
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Symptoms- unexplained fever

Symptoms- unexplained diarrhea

Symptoms- persistent cough

Symptoms- unexplained fatigue and weight loss

Symptoms- white blotches on the tongue or mouth

Stage 4 - HIV @ AIDS

} The

immune system weakens

} The

illnesses become more severe leading to an AIDS diagnosis

Opportunistic Infections associated with AIDS

}Bacterial

(TB) }Strep pneumonia

}Tuberculosis

}Viral
}Kaposi }Herpes }Influenza

Sarcoma (flu)

HIV detected by blood tests

HIV Infection and Antibody Response

---Initial Stage---- ---------------Intermediate or Latent Stage-------------Flu-like Symptoms Or No Symptoms

---Illness Stage---

Symptom-free

AIDS Symptoms

----

Infection Occurs

Virus Antibody

---< 6 month
~ Years ~ Years ~ Years ~ Years

PRVENTION IS THE ONLY CURE FOR HIV / AIDS

AIDS Looks Like

Current reported cases
}220

have full blown AIDS

Clinical Stage II

Clinical Stage III

Contd.

Contd..

Clinical Stage IV